ID	4ENHA	STANDARD;	PRT;	456	AA.
DT	CONVERTED FROM PDB (SEQRES) 4ENH
DE	Cholesterol 24-hydroxylase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.500
CC	R-Factor	0.213
FT	#HET	32	  80 	PHE	A	2	602 	FVX	A	S	2
FT	#HET	56	 104 	LYS	A	1	601 	HEM	A	S	7
FT	#HET	61	 109 	TYR	A	1	601 	HEM	A	S	5
FT	#HET	73	 121 	PHE	A	2	602 	FVX	A	S	3
FT	#HET	77	 125 	LEU	A	1	601 	HEM	A	A	10
FT	#HET	78	 126 	VAL	A	1	601 	HEM	A	S	3
FT	#HET	86	 134 	TRP	A	1	601 	HEM	A	S	7
FT	#HET	90	 138 	ARG	A	1	601 	HEM	A	S	5
FT	#HET	97	 145 	PHE	A	1	601 	HEM	A	S	2
FT	#HET	171	 219 	LEU	A	2	602 	FVX	A	S	1
FT	#HET	174	 222 	ILE	A	2	602 	FVX	A	S	1
FT	#HET	251	 299 	PHE	A	1	601 	HEM	A	S	2
FT	#HET	253	 301 	ILE	A	2	602 	FVX	A	S	2
FT	#HET	254	 302 	ALA	A	1	601 	HEM	A	A	7
FT	#HET	254	 302 	ALA	A	2	602 	FVX	A	A	7
FT	#HET	255	 303 	GLY	A	1	601 	HEM	A	B	6
FT	#HET	258	 306 	THR	A	1	601 	HEM	A	A	13
FT	#HET	258	 306 	THR	A	2	602 	FVX	A	S	4
FT	#HET	259	 307 	SER	A	1	601 	HEM	A	A	5
FT	#HET	262	 310 	HIS	A	1	601 	HEM	A	S	3
FT	#HET	319	 367 	ALA	A	1	601 	HEM	A	S	1
FT	#HET	319	 367 	ALA	A	2	602 	FVX	A	S	1
FT	#HET	320	 368 	TRP	A	2	602 	FVX	A	S	13
FT	#HET	321	 369 	GLY	A	2	602 	FVX	A	B	5
FT	#HET	322	 370 	THR	A	1	601 	HEM	A	A	7
FT	#HET	322	 370 	THR	A	2	602 	FVX	A	B	1
FT	#HET	323	 371 	PHE	A	2	602 	FVX	A	S	5
FT	#HET	324	 372 	ARG	A	1	601 	HEM	A	S	1
FT	#HET	381	 429 	PRO	A	1	601 	HEM	A	B	3
FT	#HET	382	 430 	PHE	A	1	601 	HEM	A	A	14
FT	#HET	383	 431 	SER	A	1	601 	HEM	A	A	2
FT	#HET	387	 435 	ARG	A	1	601 	HEM	A	A	4
FT	#HET	388	 436 	SER	A	1	601 	HEM	A	B	1
FT	#HET	389	 437 	CYS	A	1	601 	HEM	A	A	20
FT	#HET	390	 438 	ILE	A	1	601 	HEM	A	A	4
FT	#HET	391	 439 	GLY	A	1	601 	HEM	A	B	4
FT	#HET	394	 442 	PHE	A	1	601 	HEM	A	S	1
FT	#HET	395	 443 	ALA	A	1	601 	HEM	A	S	4
FT	#HET	426	 474 	ALA	A	2	602 	FVX	A	A	3
FT	#HET	427	 475 	THR	A	2	602 	FVX	A	S	1
FT	DISORDER	1	10
FT	DISORDER	182	187
FT	DISORDER	443	456
CC	SEQUENCE	426 AA (ATOM);
CC	VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM YRALQTVFGE
CC	RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL EAKADGQTPV
CC	SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT LKRKQLREVR
CC	ESIRFLRQVG RDWVQRRREA LKRGEEVPAD ILTQILKAEE GAQDDEGLLD NFVTFFIAGH
CC	ETSANHLAFT VMELSRQPEI VARLQAEVDE VIGSKRYLDF EDLGRLQYLS QVLKESLRLY
CC	PPAWGTFRLL EEETLIDGVR VPGNTPLLFS TYVMGRMDTY FEDPLTFNPD RFGPGAPKPR
CC	FTYFPFSLGH RSCIGQQFAQ MEVKVVMAKL LQRLEFRLVP GQRFGLQEQA TLKPLDPVLC
CC	TLRPRG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	ATOM   ----------VLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	                 ****************************************
CC	SEQRES STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	ATOM   STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	       **************************************************
CC	SEQRES SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	ATOM   SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	       **************************************************
CC	SEQRES METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	ATOM   METSMLLGAQKPLSQAVKLMLEGITASRNTL------KRKQLREVRESIR
CC	       *******************************      *************
CC	SEQRES FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	ATOM   FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	       **************************************************
CC	SEQRES FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	ATOM   FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	       **************************************************
CC	SEQRES RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	ATOM   RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	       **************************************************
CC	SEQRES GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	ATOM   GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	       **************************************************
CC	SEQRES VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPP
CC	ATOM   VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRG--------
CC	       ******************************************        
CC	SEQRES PCHHHH
CC	ATOM   ------
CC	             
SQ	SEQUENCE	456 AA;      MW;         CN;
	MAKKDEVGGR VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM
	YRALQTVFGE RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL
	EAKADGQTPV SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT
	LAKFLPGKRK QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD
	DEGLLDNFVT FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG
	RLQYLSQVLK ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP
	LTFNPDRFGP GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF
	GLQEQATLKP LDPVLCTLRP RGWQPAPPPP PCHHHH
//