ID	4EFKA	STANDARD;	PRT;	300	AA.
DT	CONVERTED FROM PDB (SEQRES) 4EFK
DE	Pantothenate synthetase
OS	Mycobacterium tuberculosis
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.700
CC	R-Factor	0.173
FT	#SUB	25	  25 	ARG	A	178	 178 	ASP	B	Protein	S	3
FT	#SUB	115	 115 	ARG	A	119	 119 	GLN	B	Protein	B	1
FT	#SUB	115	 115 	ARG	A	120	 120 	PRO	B	Protein	B	1
FT	#SUB	115	 115 	ARG	A	121	 121 	GLY	B	Protein	B	4
FT	#SUB	115	 115 	ARG	A	170	 170 	GLN	B	Protein	S	16
FT	#SUB	115	 115 	ARG	A	174	 174 	ASP	B	Protein	A	13
FT	#SUB	116	 116 	THR	A	118	 118 	VAL	B	Protein	S	1
FT	#SUB	116	 116 	THR	A	119	 119 	GLN	B	Protein	A	3
FT	#SUB	116	 116 	THR	A	170	 170 	GLN	B	Protein	S	2
FT	#SUB	116	 116 	THR	A	171	 171 	LEU	B	Protein	S	3
FT	#SUB	116	 116 	THR	A	174	 174 	ASP	B	Protein	A	9
FT	#SUB	116	 116 	THR	A	175	 175 	PHE	B	Protein	A	4
FT	#SUB	117	 117 	THR	A	118	 118 	VAL	B	Protein	B	2
FT	#SUB	117	 117 	THR	A	119	 119 	GLN	B	Protein	A	10
FT	#SUB	117	 117 	THR	A	175	 175 	PHE	B	Protein	B	5
FT	#SUB	118	 118 	VAL	A	116	 116 	THR	B	Protein	S	1
FT	#SUB	118	 118 	VAL	A	117	 117 	THR	B	Protein	B	2
FT	#SUB	118	 118 	VAL	A	175	 175 	PHE	B	Protein	S	1
FT	#SUB	119	 119 	GLN	A	116	 116 	THR	B	Protein	B	3
FT	#SUB	119	 119 	GLN	A	117	 117 	THR	B	Protein	A	11
FT	#SUB	119	 119 	GLN	A	119	 119 	GLN	B	Protein	S	1
FT	#SUB	121	 121 	GLY	A	115	 115 	ARG	B	Protein	B	4
FT	#SUB	144	 144 	LEU	A	175	 175 	PHE	B	Protein	S	4
FT	#SUB	145	 145 	LYS	A	174	 174 	ASP	B	Protein	S	4
FT	#SUB	145	 145 	LYS	A	175	 175 	PHE	B	Protein	S	1
FT	#SUB	145	 145 	LYS	A	176	 176 	ASN	B	Protein	A	7
FT	#SUB	148	 148 	GLN	A	148	 148 	GLN	B	Protein	S	6
FT	#SUB	148	 148 	GLN	A	151	 151 	ARG	B	Protein	S	1
FT	#SUB	148	 148 	GLN	A	175	 175 	PHE	B	Protein	S	2
FT	#SUB	148	 148 	GLN	A	176	 176 	ASN	B	Protein	A	4
FT	#SUB	148	 148 	GLN	A	177	 177 	LEU	B	Protein	S	3
FT	#SUB	149	 149 	ILE	A	176	 176 	ASN	B	Protein	S	3
FT	#SUB	151	 151 	ARG	A	151	 151 	ARG	B	Protein	S	12
FT	#SUB	151	 151 	ARG	A	176	 176 	ASN	B	Protein	S	1
FT	#SUB	151	 151 	ARG	A	177	 177 	LEU	B	Protein	S	2
FT	#SUB	151	 151 	ARG	A	178	 178 	ASP	B	Protein	S	9
FT	#SUB	170	 170 	GLN	A	115	 115 	ARG	B	Protein	A	15
FT	#SUB	170	 170 	GLN	A	116	 116 	THR	B	Protein	A	3
FT	#SUB	171	 171 	LEU	A	116	 116 	THR	B	Protein	B	2
FT	#SUB	174	 174 	ASP	A	115	 115 	ARG	B	Protein	S	12
FT	#SUB	174	 174 	ASP	A	116	 116 	THR	B	Protein	S	9
FT	#SUB	174	 174 	ASP	A	145	 145 	LYS	B	Protein	B	5
FT	#SUB	175	 175 	PHE	A	116	 116 	THR	B	Protein	S	3
FT	#SUB	175	 175 	PHE	A	117	 117 	THR	B	Protein	S	5
FT	#SUB	175	 175 	PHE	A	118	 118 	VAL	B	Protein	S	2
FT	#SUB	175	 175 	PHE	A	144	 144 	LEU	B	Protein	S	3
FT	#SUB	175	 175 	PHE	A	145	 145 	LYS	B	Protein	B	1
FT	#SUB	175	 175 	PHE	A	148	 148 	GLN	B	Protein	B	2
FT	#SUB	176	 176 	ASN	A	145	 145 	LYS	B	Protein	S	7
FT	#SUB	176	 176 	ASN	A	148	 148 	GLN	B	Protein	B	4
FT	#SUB	176	 176 	ASN	A	149	 149 	ILE	B	Protein	S	6
FT	#SUB	177	 177 	LEU	A	148	 148 	GLN	B	Protein	S	3
FT	#SUB	178	 178 	ASP	A	25	  25 	ARG	B	Protein	S	1
FT	#HET	24	  24 	SER	A	7	407 	EOH	A	A	4
FT	#HET	25	  25 	ARG	A	7	407 	EOH	A	B	2
FT	#HET	28	  28 	ARG	A	7	407 	EOH	A	S	4
FT	#HET	38	  38 	PRO	A	1	401 	0OC	A	A	7
FT	#HET	39	  39 	THR	A	1	401 	0OC	A	B	4
FT	#HET	40	  40 	MET	A	1	401 	0OC	A	S	3
FT	#HET	67	  67 	PHE	A	1	401 	0OC	A	B	2
FT	#HET	69	  69 	ASN	A	1	401 	0OC	A	A	2
FT	#HET	70	  70 	PRO	A	2	402 	0OC	A	S	1
FT	#HET	70	  70 	PRO	A	6	406 	IMD	A	S	3
FT	#HET	71	  71 	MET	A	2	402 	0OC	A	B	1
FT	#HET	72	  72 	GLN	A	2	402 	0OC	A	A	8
FT	#HET	72	  72 	GLN	A	6	406 	IMD	A	S	3
FT	#HET	109	 109 	MET	A	3	403 	GOL	A	B	3
FT	#HET	110	 110 	TYR	A	3	403 	GOL	A	A	7
FT	#HET	110	 110 	TYR	A	6	406 	IMD	A	S	6
FT	#HET	111	 111 	PRO	A	3	403 	GOL	A	A	2
FT	#HET	112	 112 	ASP	A	3	403 	GOL	A	A	5
FT	#HET	113	 113 	GLY	A	3	403 	GOL	A	B	7
FT	#HET	114	 114 	LEU	A	3	403 	GOL	A	B	2
FT	#HET	114	 114 	LEU	A	4	404 	EOH	A	B	3
FT	#HET	114	 114 	LEU	A	6	406 	IMD	A	S	8
FT	#HET	115	 115 	ARG	A	3	403 	GOL	A	A	4
FT	#HET	115	 115 	ARG	A	4	404 	EOH	A	B	5
FT	#HET	116	 116 	THR	A	3	403 	GOL	A	B	4
FT	#HET	117	 117 	THR	A	4	404 	EOH	A	A	6
FT	#HET	139	 139 	VAL	A	1	401 	0OC	A	S	1
FT	#HET	142	 142 	VAL	A	1	401 	0OC	A	S	6
FT	#HET	143	 143 	VAL	A	1	401 	0OC	A	A	5
FT	#HET	145	 145 	LYS	A	3	403 	GOL	A	S	4
FT	#HET	146	 146 	LEU	A	1	401 	0OC	A	S	2
FT	#HET	150	 150 	VAL	A	7	407 	EOH	A	B	1
FT	#HET	151	 151 	ARG	A	7	407 	EOH	A	B	3
FT	#HET	157	 157 	PHE	A	1	401 	0OC	A	S	1
FT	#HET	164	 164 	GLN	A	1	401 	0OC	A	S	3
FT	#HET	178	 178 	ASP	A	11	404 	GOL	B	S	7
FT	#HET	218	 218 	THR	A	5	405 	EOH	A	S	3
FT	DISORDER	1	3
FT	DISORDER	74	80
FT	DISORDER	260	261
FT	DISORDER	293	300
CC	Miss-SC	1
CC	SEQUENCE	280 AA (ATOM);
CC	PAFHPGELNV YSAPGDVADV SRALRLTGRR VMLVPTMGAL HEGHLALVRA AKRVPGSVVV
CC	VSIFVNPMQF AYPRTPDDDL AQLRAEGVEI AFTPTTAAMY PDGLRTTVQP GPLAAELEGG
CC	PRPTHFAGVL TVVLKLLQIV RPDRVFFGEK DYQQLVLIRQ LVADFNLDVA VVGVPTVREA
CC	DGLAMSSRNR YLDPAQRAAA VALSAALTAA AHAATAGAQA ALDAARAVLD AAPGVAVDYL
CC	ELRDIGLGPL NGSGRLLVAA RLGTTRLLDN IAIEIGTFAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLAL
CC	ATOM   ---PAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLAL
CC	          ***********************************************
CC	SEQRES VRAAKRVPGSVVVVSIFVNPMQFGAGGDLDAYPRTPDDDLAQLRAEGVEI
CC	ATOM   VRAAKRVPGSVVVVSIFVNPMQF-------AYPRTPDDDLAQLRAEGVEI
CC	       ***********************       ********************
CC	SEQRES AFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIV
CC	ATOM   AFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIV
CC	       **************************************************
CC	SEQRES RPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNR
CC	ATOM   RPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNR
CC	       **************************************************
CC	SEQRES YLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYL
CC	ATOM   YLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYL
CC	       **************************************************
CC	SEQRES ELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
CC	ATOM   ELRDIGLGP--LNGSGRLLVAARLGTTRLLDNIAIEIGTFAG--------
CC	       *********  *******************************        
CC	SEQRES 
CC	ATOM   
CC	       
SQ	SEQUENCE	300 AA;      MW;         CN;
	MAIPAFHPGE LNVYSAPGDV ADVSRALRLT GRRVMLVPTM GALHEGHLAL VRAAKRVPGS
	VVVVSIFVNP MQFGAGGDLD AYPRTPDDDL AQLRAEGVEI AFTPTTAAMY PDGLRTTVQP
	GPLAAELEGG PRPTHFAGVL TVVLKLLQIV RPDRVFFGEK DYQQLVLIRQ LVADFNLDVA
	VVGVPTVREA DGLAMSSRNR YLDPAQRAAA VALSAALTAA AHAATAGAQA ALDAARAVLD
	AAPGVAVDYL ELRDIGLGPM PLNGSGRLLV AARLGTTRLL DNIAIEIGTF AGTDRPDGYR
//
ID	4EFKB	STANDARD;	PRT;	300	AA.
DT	CONVERTED FROM PDB (SEQRES) 4EFK
DE	Pantothenate synthetase
OS	Mycobacterium tuberculosis
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.700
CC	R-Factor	0.173
FT	#SUB	25	  25 	ARG	B	178	 178 	ASP	A	Protein	S	1
FT	#SUB	115	 115 	ARG	B	121	 121 	GLY	A	Protein	A	4
FT	#SUB	115	 115 	ARG	B	170	 170 	GLN	A	Protein	S	15
FT	#SUB	115	 115 	ARG	B	174	 174 	ASP	A	Protein	A	12
FT	#SUB	116	 116 	THR	B	118	 118 	VAL	A	Protein	S	1
FT	#SUB	116	 116 	THR	B	119	 119 	GLN	A	Protein	A	3
FT	#SUB	116	 116 	THR	B	170	 170 	GLN	A	Protein	S	3
FT	#SUB	116	 116 	THR	B	171	 171 	LEU	A	Protein	S	2
FT	#SUB	116	 116 	THR	B	174	 174 	ASP	A	Protein	A	9
FT	#SUB	116	 116 	THR	B	175	 175 	PHE	A	Protein	A	3
FT	#SUB	117	 117 	THR	B	118	 118 	VAL	A	Protein	B	2
FT	#SUB	117	 117 	THR	B	119	 119 	GLN	A	Protein	A	11
FT	#SUB	117	 117 	THR	B	175	 175 	PHE	A	Protein	B	5
FT	#SUB	118	 118 	VAL	B	116	 116 	THR	A	Protein	S	1
FT	#SUB	118	 118 	VAL	B	117	 117 	THR	A	Protein	B	2
FT	#SUB	118	 118 	VAL	B	175	 175 	PHE	A	Protein	A	2
FT	#SUB	119	 119 	GLN	B	115	 115 	ARG	A	Protein	B	1
FT	#SUB	119	 119 	GLN	B	116	 116 	THR	A	Protein	B	3
FT	#SUB	119	 119 	GLN	B	117	 117 	THR	A	Protein	A	10
FT	#SUB	119	 119 	GLN	B	119	 119 	GLN	A	Protein	S	1
FT	#SUB	120	 120 	PRO	B	115	 115 	ARG	A	Protein	B	1
FT	#SUB	121	 121 	GLY	B	115	 115 	ARG	A	Protein	B	4
FT	#SUB	144	 144 	LEU	B	175	 175 	PHE	A	Protein	S	3
FT	#SUB	145	 145 	LYS	B	174	 174 	ASP	A	Protein	S	5
FT	#SUB	145	 145 	LYS	B	175	 175 	PHE	A	Protein	S	1
FT	#SUB	145	 145 	LYS	B	176	 176 	ASN	A	Protein	A	7
FT	#SUB	148	 148 	GLN	B	148	 148 	GLN	A	Protein	S	6
FT	#SUB	148	 148 	GLN	B	175	 175 	PHE	A	Protein	S	2
FT	#SUB	148	 148 	GLN	B	176	 176 	ASN	A	Protein	A	4
FT	#SUB	148	 148 	GLN	B	177	 177 	LEU	A	Protein	S	3
FT	#SUB	149	 149 	ILE	B	176	 176 	ASN	A	Protein	S	6
FT	#SUB	151	 151 	ARG	B	148	 148 	GLN	A	Protein	S	1
FT	#SUB	151	 151 	ARG	B	151	 151 	ARG	A	Protein	S	12
FT	#SUB	170	 170 	GLN	B	115	 115 	ARG	A	Protein	A	16
FT	#SUB	170	 170 	GLN	B	116	 116 	THR	A	Protein	B	2
FT	#SUB	171	 171 	LEU	B	116	 116 	THR	A	Protein	A	3
FT	#SUB	174	 174 	ASP	B	115	 115 	ARG	A	Protein	S	13
FT	#SUB	174	 174 	ASP	B	116	 116 	THR	A	Protein	S	9
FT	#SUB	174	 174 	ASP	B	145	 145 	LYS	A	Protein	B	4
FT	#SUB	175	 175 	PHE	B	116	 116 	THR	A	Protein	S	4
FT	#SUB	175	 175 	PHE	B	117	 117 	THR	A	Protein	S	5
FT	#SUB	175	 175 	PHE	B	118	 118 	VAL	A	Protein	S	1
FT	#SUB	175	 175 	PHE	B	144	 144 	LEU	A	Protein	S	4
FT	#SUB	175	 175 	PHE	B	145	 145 	LYS	A	Protein	B	1
FT	#SUB	175	 175 	PHE	B	148	 148 	GLN	A	Protein	B	2
FT	#SUB	176	 176 	ASN	B	145	 145 	LYS	A	Protein	S	7
FT	#SUB	176	 176 	ASN	B	148	 148 	GLN	A	Protein	B	4
FT	#SUB	176	 176 	ASN	B	149	 149 	ILE	A	Protein	S	3
FT	#SUB	176	 176 	ASN	B	151	 151 	ARG	A	Protein	B	1
FT	#SUB	177	 177 	LEU	B	148	 148 	GLN	A	Protein	S	3
FT	#SUB	177	 177 	LEU	B	151	 151 	ARG	A	Protein	B	2
FT	#SUB	178	 178 	ASP	B	25	  25 	ARG	A	Protein	S	3
FT	#SUB	178	 178 	ASP	B	151	 151 	ARG	A	Protein	A	9
FT	#HET	6	   6 	PHE	B	12	405 	EOH	B	S	1
FT	#HET	21	  21 	ALA	B	11	404 	GOL	B	A	8
FT	#HET	24	  24 	SER	B	11	404 	GOL	B	S	2
FT	#HET	25	  25 	ARG	B	11	404 	GOL	B	A	7
FT	#HET	26	  26 	ALA	B	12	405 	EOH	B	S	1
FT	#HET	27	  27 	LEU	B	12	405 	EOH	B	S	1
FT	#HET	38	  38 	PRO	B	8	401 	0OC	B	A	7
FT	#HET	39	  39 	THR	B	8	401 	0OC	B	B	2
FT	#HET	39	  39 	THR	B	13	406 	EOH	B	A	3
FT	#HET	40	  40 	MET	B	8	401 	0OC	B	S	1
FT	#HET	40	  40 	MET	B	13	406 	EOH	B	A	5
FT	#HET	44	  44 	HIS	B	10	403 	SO4	B	S	2
FT	#HET	46	  46 	GLY	B	10	403 	SO4	B	B	2
FT	#HET	47	  47 	HIS	B	10	403 	SO4	B	S	3
FT	#HET	47	  47 	HIS	B	13	406 	EOH	B	S	2
FT	#HET	50	  50 	LEU	B	10	403 	SO4	B	S	1
FT	#HET	67	  67 	PHE	B	8	401 	0OC	B	B	2
FT	#HET	69	  69 	ASN	B	8	401 	0OC	B	A	2
FT	#HET	119	 119 	GLN	B	4	404 	EOH	A	A	2
FT	#HET	120	 120 	PRO	B	4	404 	EOH	A	B	1
FT	#HET	126	 126 	GLU	B	15	408 	EOH	B	S	1
FT	#HET	139	 139 	VAL	B	8	401 	0OC	B	A	2
FT	#HET	142	 142 	VAL	B	8	401 	0OC	B	S	6
FT	#HET	143	 143 	VAL	B	8	401 	0OC	B	A	4
FT	#HET	146	 146 	LEU	B	8	401 	0OC	B	S	2
FT	#HET	148	 148 	GLN	B	11	404 	GOL	B	B	3
FT	#HET	149	 149 	ILE	B	11	404 	GOL	B	B	7
FT	#HET	150	 150 	VAL	B	11	404 	GOL	B	B	2
FT	#HET	151	 151 	ARG	B	11	404 	GOL	B	S	4
FT	#HET	157	 157 	PHE	B	8	401 	0OC	B	S	1
FT	#HET	160	 160 	LYS	B	10	403 	SO4	B	S	1
FT	#HET	161	 161 	ASP	B	10	403 	SO4	B	S	1
FT	#HET	164	 164 	GLN	B	8	401 	0OC	B	S	3
FT	#HET	174	 174 	ASP	B	3	403 	GOL	A	A	10
FT	#HET	206	 206 	GLN	B	14	407 	EOH	B	S	4
FT	#HET	244	 244 	GLY	B	9	402 	GOL	B	B	5
FT	#HET	246	 246 	ALA	B	9	402 	GOL	B	A	3
FT	#HET	253	 253 	ARG	B	15	408 	EOH	B	S	6
FT	#HET	257	 257 	LEU	B	15	408 	EOH	B	B	2
FT	#HET	258	 258 	GLY	B	15	408 	EOH	B	B	5
FT	#HET	259	 259 	PRO	B	15	408 	EOH	B	A	5
FT	#HET	273	 273 	ARG	B	9	402 	GOL	B	A	6
FT	#HET	274	 274 	LEU	B	9	402 	GOL	B	B	3
FT	#HET	275	 275 	GLY	B	9	402 	GOL	B	B	7
FT	#HET	275	 275 	GLY	B	14	407 	EOH	B	B	5
FT	#HET	276	 276 	THR	B	14	407 	EOH	B	A	7
FT	DISORDER	71	84
FT	DISORDER	289	300
CC	SEQUENCE	274 AA (ATOM);
CC	MAIPAFHPGE LNVYSAPGDV ADVSRALRLT GRRVMLVPTM GALHEGHLAL VRAAKRVPGS
CC	VVVVSIFVNP TPDDDLAQLR AEGVEIAFTP TTAAMYPDGL RTTVQPGPLA AELEGGPRPT
CC	HFAGVLTVVL KLLQIVRPDR VFFGEKDYQQ LVLIRQLVAD FNLDVAVVGV PTVREADGLA
CC	MSSRNRYLDP AQRAAAVALS AALTAAAHAA TAGAQAALDA ARAVLDAAPG VAVDYLELRD
CC	IGLGPMPLNG SGRLLVAARL GTTRLLDNIA IEIG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLAL
CC	ATOM   MAIPAFHPGELNVYSAPGDVADVSRALRLTGRRVMLVPTMGALHEGHLAL
CC	       **************************************************
CC	SEQRES VRAAKRVPGSVVVVSIFVNPMQFGAGGDLDAYPRTPDDDLAQLRAEGVEI
CC	ATOM   VRAAKRVPGSVVVVSIFVNP--------------TPDDDLAQLRAEGVEI
CC	       ********************              ****************
CC	SEQRES AFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIV
CC	ATOM   AFTPTTAAMYPDGLRTTVQPGPLAAELEGGPRPTHFAGVLTVVLKLLQIV
CC	       **************************************************
CC	SEQRES RPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNR
CC	ATOM   RPDRVFFGEKDYQQLVLIRQLVADFNLDVAVVGVPTVREADGLAMSSRNR
CC	       **************************************************
CC	SEQRES YLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYL
CC	ATOM   YLDPAQRAAAVALSAALTAAAHAATAGAQAALDAARAVLDAAPGVAVDYL
CC	       **************************************************
CC	SEQRES ELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIGTFAGTDRPDGYR
CC	ATOM   ELRDIGLGPMPLNGSGRLLVAARLGTTRLLDNIAIEIG------------
CC	       **************************************            
CC	SEQRES 
CC	ATOM   
CC	       
SQ	SEQUENCE	300 AA;      MW;         CN;
	MAIPAFHPGE LNVYSAPGDV ADVSRALRLT GRRVMLVPTM GALHEGHLAL VRAAKRVPGS
	VVVVSIFVNP MQFGAGGDLD AYPRTPDDDL AQLRAEGVEI AFTPTTAAMY PDGLRTTVQP
	GPLAAELEGG PRPTHFAGVL TVVLKLLQIV RPDRVFFGEK DYQQLVLIRQ LVADFNLDVA
	VVGVPTVREA DGLAMSSRNR YLDPAQRAAA VALSAALTAA AHAATAGAQA ALDAARAVLD
	AAPGVAVDYL ELRDIGLGPM PLNGSGRLLV AARLGTTRLL DNIAIEIGTF AGTDRPDGYR
//