ID	4E4MA	STANDARD;	PRT;	302	AA.
DT	CONVERTED FROM PDB (SEQRES) 4E4M
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.193
FT	#SUB	22	 852 	LEU	A	101	 931 	TYR	B	Protein	S	2
FT	#SUB	22	 852 	LEU	A	103	 933 	PRO	B	Protein	A	4
FT	#SUB	23	 853 	GLN	A	23	 853 	GLN	B	Protein	S	5
FT	#SUB	25	 855 	LEU	A	23	 853 	GLN	B	Protein	S	1
FT	#SUB	35	 865 	MET	A	23	 853 	GLN	B	Protein	S	3
FT	#SUB	35	 865 	MET	A	35	 865 	MET	B	Protein	S	2
FT	#SUB	37	 867 	ARG	A	48	 878 	VAL	B	Protein	S	2
FT	#SUB	44	 874 	ASN	A	47	 877 	GLU	B	Protein	B	1
FT	#SUB	45	 875 	THR	A	45	 875 	THR	B	Protein	B	4
FT	#SUB	47	 877 	GLU	A	44	 874 	ASN	B	Protein	S	1
FT	#SUB	48	 878 	VAL	A	37	 867 	ARG	B	Protein	A	2
FT	#SUB	101	 931 	TYR	A	22	 852 	LEU	B	Protein	S	6
FT	#SUB	101	 931 	TYR	A	23	 853 	GLN	B	Protein	S	3
FT	#SUB	103	 933 	PRO	A	21	 851 	PHE	B	Protein	A	3
FT	#SUB	103	 933 	PRO	A	22	 852 	LEU	B	Protein	A	5
FT	#SUB	104	 934 	TYR	A	21	 851 	PHE	B	Protein	S	4
FT	#SUB	16	 846 	GLU	A	298	1128 	ASP	D	Protein	S	1
FT	#SUB	21	 851 	PHE	A	302	1132 	GLY	D	Protein	S	8
FT	#SUB	53	 883 	LYS	A	299	1129 	ASN	D	Protein	S	7
FT	#SUB	53	 883 	LYS	A	300	1130 	MET	D	Protein	S	2
FT	#SUB	53	 883 	LYS	A	301	1131 	ALA	D	Protein	S	2
FT	#SUB	54	 884 	LEU	A	299	1129 	ASN	D	Protein	B	4
FT	#SUB	55	 885 	GLN	A	299	1129 	ASN	D	Protein	S	2
FT	#SUB	56	 886 	HIS	A	267	1097 	GLU	D	Protein	A	4
FT	#SUB	89	 919 	SER	A	298	1128 	ASP	D	Protein	S	6
FT	#SUB	90	 920 	ALA	A	298	1128 	ASP	D	Protein	A	4
FT	#SUB	93	 923 	ARG	A	291	1121 	LEU	D	Protein	S	4
FT	#SUB	93	 923 	ARG	A	294	1124 	ASP	D	Protein	S	4
FT	#SUB	93	 923 	ARG	A	295	1125 	GLN	D	Protein	B	3
FT	#SUB	94	 924 	ASN	A	295	1125 	GLN	D	Protein	S	4
FT	#SUB	94	 924 	ASN	A	298	1128 	ASP	D	Protein	S	5
FT	#SUB	94	 924 	ASN	A	299	1129 	ASN	D	Protein	S	3
FT	#SUB	96	 926 	LYS	A	298	1128 	ASP	D	Protein	S	4
FT	#SUB	5	 835 	ALA	A	172	1002 	PRO	E	Protein	A	3
FT	#SUB	5	 835 	ALA	A	175	1005 	LYS	E	Protein	B	2
FT	#SUB	5	 835 	ALA	A	177	1007 	PTR	E	Protein	A	5
FT	#SUB	5	 835 	ALA	A	178	1008 	PTR	E	Protein	A	4
FT	#SUB	5	 835 	ALA	A	179	1009 	LYS	E	Protein	B	5
FT	#SUB	6	 836 	PHE	A	179	1009 	LYS	E	Protein	A	11
FT	#SUB	6	 836 	PHE	A	181	1011 	LYS	E	Protein	S	1
FT	#SUB	7	 837 	GLU	A	169	 999 	LYS	E	Protein	S	5
FT	#SUB	7	 837 	GLU	A	178	1008 	PTR	E	Protein	S	17
FT	#SUB	7	 837 	GLU	A	179	1009 	LYS	E	Protein	A	4
FT	#SUB	7	 837 	GLU	A	180	1010 	VAL	E	Protein	B	2
FT	#SUB	7	 837 	GLU	A	181	1011 	LYS	E	Protein	B	2
FT	#SUB	7	 837 	GLU	A	182	1012 	GLU	E	Protein	S	1
FT	#SUB	8	 838 	ASP	A	181	1011 	LYS	E	Protein	S	2
FT	#SUB	9	 839 	ARG	A	60	 890 	GLU	E	Protein	S	6
FT	#SUB	9	 839 	ARG	A	64	 894 	ASP	E	Protein	S	8
FT	#SUB	9	 839 	ARG	A	181	1011 	LYS	E	Protein	A	4
FT	#SUB	9	 839 	ARG	A	182	1012 	GLU	E	Protein	S	5
FT	#SUB	9	 839 	ARG	A	183	1013 	PRO	E	Protein	B	1
FT	#SUB	10	 840 	ASP	A	181	1011 	LYS	E	Protein	A	2
FT	#SUB	10	 840 	ASP	A	182	1012 	GLU	E	Protein	S	2
FT	#SUB	10	 840 	ASP	A	183	1013 	PRO	E	Protein	S	4
FT	#SUB	13	 843 	GLN	A	181	1011 	LYS	E	Protein	B	3
FT	#SUB	13	 843 	GLN	A	182	1012 	GLU	E	Protein	S	2
FT	#SUB	15	 845 	GLU	A	179	1009 	LYS	E	Protein	S	4
FT	#SUB	15	 845 	GLU	A	181	1011 	LYS	E	Protein	S	1
FT	#SUB	59	 889 	GLU	A	238	1068 	ASP	E	Protein	S	2
FT	#SUB	59	 889 	GLU	A	243	1073 	MET	E	Protein	S	3
FT	#SUB	62	 892 	LEU	A	243	1073 	MET	E	Protein	S	1
FT	#SUB	62	 892 	LEU	A	246	1076 	PHE	E	Protein	S	2
FT	#SUB	63	 893 	ARG	A	240	1070 	GLN	E	Protein	S	6
FT	#SUB	63	 893 	ARG	A	241	1071 	GLY	E	Protein	S	1
FT	#SUB	66	 896 	GLU	A	241	1071 	GLY	E	Protein	S	2
FT	#SUB	66	 896 	GLU	A	242	1072 	GLN	E	Protein	S	6
FT	#SUB	88	 918 	TYR	A	242	1072 	GLN	E	Protein	S	5
FT	#SUB	91	 921 	GLY	A	197	1027 	THR	E	Protein	B	1
FT	#SUB	92	 922 	ARG	A	196	1026 	LEU	E	Protein	S	3
FT	#SUB	92	 922 	ARG	A	197	1027 	THR	E	Protein	S	9
FT	#SUB	92	 922 	ARG	A	198	1028 	GLU	E	Protein	S	1
FT	#SUB	92	 922 	ARG	A	199	1029 	SER	E	Protein	S	6
FT	#SUB	92	 922 	ARG	A	246	1076 	PHE	E	Protein	B	2
FT	#SUB	92	 922 	ARG	A	249	1079 	ILE	E	Protein	A	2
FT	#SUB	93	 923 	ARG	A	246	1076 	PHE	E	Protein	A	9
FT	#SUB	93	 923 	ARG	A	249	1079 	ILE	E	Protein	S	2
FT	#SUB	93	 923 	ARG	A	250	1080 	GLU	E	Protein	S	5
FT	#SUB	93	 923 	ARG	A	253	1083 	LYS	E	Protein	S	1
FT	#SUB	94	 924 	ASN	A	246	1076 	PHE	E	Protein	B	6
FT	#HET	25	 855 	LEU	A	1	1201 	0NH	A	A	7
FT	#HET	26	 856 	GLY	A	1	1201 	0NH	A	B	2
FT	#HET	27	 857 	LYS	A	1	1201 	0NH	A	B	3
FT	#HET	28	 858 	GLY	A	1	1201 	0NH	A	B	2
FT	#HET	33	 863 	VAL	A	1	1201 	0NH	A	S	4
FT	#HET	50	 880 	ALA	A	1	1201 	0NH	A	S	3
FT	#HET	99	 929 	MET	A	1	1201 	0NH	A	S	1
FT	#HET	100	 930 	GLU	A	1	1201 	0NH	A	B	3
FT	#HET	101	 931 	TYR	A	1	1201 	0NH	A	A	5
FT	#HET	102	 932 	LEU	A	1	1201 	0NH	A	B	9
FT	#HET	105	 935 	GLY	A	1	1201 	0NH	A	B	3
FT	#HET	150	 980 	ARG	A	1	1201 	0NH	A	B	1
FT	#HET	151	 981 	ASN	A	1	1201 	0NH	A	S	1
FT	#HET	153	 983 	LEU	A	1	1201 	0NH	A	S	5
FT	#HET	164	 994 	ASP	A	1	1201 	0NH	A	A	5
FT	DISORDER	1	4
CC	SEQUENCE	298 AA (ATOM);
CC	AFEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
CC	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
CC	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
CC	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
CC	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	ATOM   ----AFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	           **********************************************
CC	SEQRES VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	ATOM   VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	       **************************************************
CC	SEQRES YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	ATOM   YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	       **************************************************
CC	SEQRES NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	ATOM   NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	       **************************************************
CC	SEQRES FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	ATOM   FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	       **************************************************
CC	SEQRES LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	ATOM   LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	       **************************************************
CC	SEQRES AG
CC	ATOM   AG
CC	       **
SQ	SEQUENCE	302 AA;      MW;         CN;
	GSSGAFEDRD PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA VKKLQHSTEE
	HLRDFEREIE ILKSLQHDNI VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH
	IKLLQYTSQI CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV LPQDKEYYKV
	KEPGESPIFW YAPESLTESK FSVASDVWSF GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ
	GQMIVFHLIE LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA LRVDQIRDNM
	AG
//
ID	4E4MB	STANDARD;	PRT;	302	AA.
DT	CONVERTED FROM PDB (SEQRES) 4E4M
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.193
FT	#SUB	21	 851 	PHE	B	103	 933 	PRO	A	Protein	A	3
FT	#SUB	21	 851 	PHE	B	104	 934 	TYR	A	Protein	S	4
FT	#SUB	22	 852 	LEU	B	101	 931 	TYR	A	Protein	A	6
FT	#SUB	22	 852 	LEU	B	103	 933 	PRO	A	Protein	B	5
FT	#SUB	23	 853 	GLN	B	23	 853 	GLN	A	Protein	S	5
FT	#SUB	23	 853 	GLN	B	25	 855 	LEU	A	Protein	S	1
FT	#SUB	23	 853 	GLN	B	35	 865 	MET	A	Protein	S	3
FT	#SUB	23	 853 	GLN	B	101	 931 	TYR	A	Protein	S	3
FT	#SUB	35	 865 	MET	B	35	 865 	MET	A	Protein	S	2
FT	#SUB	37	 867 	ARG	B	48	 878 	VAL	A	Protein	S	2
FT	#SUB	44	 874 	ASN	B	47	 877 	GLU	A	Protein	S	1
FT	#SUB	45	 875 	THR	B	45	 875 	THR	A	Protein	A	4
FT	#SUB	47	 877 	GLU	B	44	 874 	ASN	A	Protein	B	1
FT	#SUB	48	 878 	VAL	B	37	 867 	ARG	A	Protein	S	2
FT	#SUB	101	 931 	TYR	B	22	 852 	LEU	A	Protein	S	2
FT	#SUB	103	 933 	PRO	B	22	 852 	LEU	A	Protein	A	4
FT	#SUB	113	 943 	LYS	B	302	1132 	GLY	D	Protein	S	4
FT	#SUB	114	 944 	HIS	B	302	1132 	GLY	D	Protein	S	2
FT	#SUB	115	 945 	LYS	B	116	 946 	GLU	D	Protein	B	1
FT	#SUB	116	 946 	GLU	B	116	 946 	GLU	D	Protein	B	3
FT	#SUB	116	 946 	GLU	B	117	 947 	ARG	D	Protein	B	1
FT	#SUB	116	 946 	GLU	B	118	 948 	ILE	D	Protein	B	3
FT	#SUB	116	 946 	GLU	B	119	 949 	ASP	D	Protein	A	5
FT	#SUB	117	 947 	ARG	B	116	 946 	GLU	D	Protein	B	1
FT	#SUB	117	 947 	ARG	B	117	 947 	ARG	D	Protein	A	8
FT	#SUB	117	 947 	ARG	B	119	 949 	ASP	D	Protein	S	6
FT	#SUB	117	 947 	ARG	B	121	 951 	ILE	D	Protein	S	1
FT	#SUB	118	 948 	ILE	B	116	 946 	GLU	D	Protein	B	3
FT	#SUB	119	 949 	ASP	B	116	 946 	GLU	D	Protein	A	5
FT	#SUB	119	 949 	ASP	B	117	 947 	ARG	D	Protein	S	4
FT	#HET	25	 855 	LEU	B	2	1201 	0NH	B	A	7
FT	#HET	27	 857 	LYS	B	2	1201 	0NH	B	B	2
FT	#HET	28	 858 	GLY	B	2	1201 	0NH	B	B	1
FT	#HET	33	 863 	VAL	B	2	1201 	0NH	B	S	1
FT	#HET	50	 880 	ALA	B	2	1201 	0NH	B	S	2
FT	#HET	100	 930 	GLU	B	2	1201 	0NH	B	B	2
FT	#HET	101	 931 	TYR	B	2	1201 	0NH	B	A	5
FT	#HET	102	 932 	LEU	B	2	1201 	0NH	B	A	12
FT	#HET	105	 935 	GLY	B	2	1201 	0NH	B	B	2
FT	#HET	150	 980 	ARG	B	2	1201 	0NH	B	B	2
FT	#HET	151	 981 	ASN	B	2	1201 	0NH	B	B	2
FT	#HET	153	 983 	LEU	B	2	1201 	0NH	B	S	3
FT	#HET	164	 994 	ASP	B	2	1201 	0NH	B	A	5
FT	DISORDER	1	4
CC	SEQUENCE	298 AA (ATOM);
CC	AFEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
CC	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
CC	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
CC	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
CC	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	ATOM   ----AFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	           **********************************************
CC	SEQRES VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	ATOM   VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	       **************************************************
CC	SEQRES YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	ATOM   YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	       **************************************************
CC	SEQRES NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	ATOM   NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	       **************************************************
CC	SEQRES FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	ATOM   FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	       **************************************************
CC	SEQRES LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	ATOM   LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	       **************************************************
CC	SEQRES AG
CC	ATOM   AG
CC	       **
SQ	SEQUENCE	302 AA;      MW;         CN;
	GSSGAFEDRD PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA VKKLQHSTEE
	HLRDFEREIE ILKSLQHDNI VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH
	IKLLQYTSQI CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV LPQDKEYYKV
	KEPGESPIFW YAPESLTESK FSVASDVWSF GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ
	GQMIVFHLIE LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA LRVDQIRDNM
	AG
//
ID	4E4MD	STANDARD;	PRT;	302	AA.
DT	CONVERTED FROM PDB (SEQRES) 4E4M
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.193
FT	#SUB	267	1097 	GLU	D	56	 886 	HIS	A	Protein	S	4
FT	#SUB	291	1121 	LEU	D	93	 923 	ARG	A	Protein	S	4
FT	#SUB	294	1124 	ASP	D	93	 923 	ARG	A	Protein	S	4
FT	#SUB	295	1125 	GLN	D	93	 923 	ARG	A	Protein	S	3
FT	#SUB	295	1125 	GLN	D	94	 924 	ASN	A	Protein	S	4
FT	#SUB	298	1128 	ASP	D	16	 846 	GLU	A	Protein	S	1
FT	#SUB	298	1128 	ASP	D	89	 919 	SER	A	Protein	S	6
FT	#SUB	298	1128 	ASP	D	90	 920 	ALA	A	Protein	S	4
FT	#SUB	298	1128 	ASP	D	94	 924 	ASN	A	Protein	S	5
FT	#SUB	298	1128 	ASP	D	96	 926 	LYS	A	Protein	A	4
FT	#SUB	299	1129 	ASN	D	53	 883 	LYS	A	Protein	A	7
FT	#SUB	299	1129 	ASN	D	54	 884 	LEU	A	Protein	S	4
FT	#SUB	299	1129 	ASN	D	55	 885 	GLN	A	Protein	B	2
FT	#SUB	299	1129 	ASN	D	94	 924 	ASN	A	Protein	S	3
FT	#SUB	300	1130 	MET	D	53	 883 	LYS	A	Protein	B	2
FT	#SUB	301	1131 	ALA	D	53	 883 	LYS	A	Protein	B	2
FT	#SUB	302	1132 	GLY	D	21	 851 	PHE	A	Protein	B	8
FT	#SUB	116	 946 	GLU	D	115	 945 	LYS	B	Protein	B	1
FT	#SUB	116	 946 	GLU	D	116	 946 	GLU	B	Protein	B	3
FT	#SUB	116	 946 	GLU	D	117	 947 	ARG	B	Protein	B	1
FT	#SUB	116	 946 	GLU	D	118	 948 	ILE	B	Protein	B	3
FT	#SUB	116	 946 	GLU	D	119	 949 	ASP	B	Protein	A	5
FT	#SUB	117	 947 	ARG	D	116	 946 	GLU	B	Protein	B	1
FT	#SUB	117	 947 	ARG	D	117	 947 	ARG	B	Protein	B	8
FT	#SUB	117	 947 	ARG	D	119	 949 	ASP	B	Protein	S	4
FT	#SUB	118	 948 	ILE	D	116	 946 	GLU	B	Protein	B	3
FT	#SUB	119	 949 	ASP	D	116	 946 	GLU	B	Protein	A	5
FT	#SUB	119	 949 	ASP	D	117	 947 	ARG	B	Protein	S	6
FT	#SUB	121	 951 	ILE	D	117	 947 	ARG	B	Protein	S	1
FT	#SUB	302	1132 	GLY	D	113	 943 	LYS	B	Protein	B	4
FT	#SUB	302	1132 	GLY	D	114	 944 	HIS	B	Protein	B	2
FT	#SUB	77	 907 	HIS	D	254	1084 	ASN	E	Protein	S	2
FT	#SUB	132	 962 	LYS	D	250	1080 	GLU	E	Protein	S	2
FT	#SUB	132	 962 	LYS	D	253	1083 	LYS	E	Protein	S	1
FT	#SUB	132	 962 	LYS	D	254	1084 	ASN	E	Protein	A	4
FT	#SUB	135	 965 	GLU	D	250	1080 	GLU	E	Protein	S	10
FT	#SUB	135	 965 	GLU	D	254	1084 	ASN	E	Protein	S	8
FT	#SUB	136	 966 	TYR	D	254	1084 	ASN	E	Protein	B	1
FT	#SUB	136	 966 	TYR	D	255	1085 	ASN	E	Protein	S	4
FT	#SUB	139	 969 	THR	D	254	1084 	ASN	E	Protein	S	1
FT	#SUB	139	 969 	THR	D	255	1085 	ASN	E	Protein	S	8
FT	#SUB	139	 969 	THR	D	256	1086 	GLY	E	Protein	S	1
FT	#SUB	140	 970 	LYS	D	255	1085 	ASN	E	Protein	S	1
FT	#SUB	287	1117 	ARG	D	234	1064 	MET	E	Protein	S	2
FT	#SUB	287	1117 	ARG	D	235	1065 	ILE	E	Protein	S	1
FT	#SUB	287	1117 	ARG	D	247	1077 	HIS	E	Protein	S	2
FT	#SUB	287	1117 	ARG	D	250	1080 	GLU	E	Protein	S	2
FT	#SUB	287	1117 	ARG	D	251	1081 	LEU	E	Protein	S	2
FT	#SUB	288	1118 	ASP	D	247	1077 	HIS	E	Protein	S	1
FT	#SUB	290	1120 	ALA	D	250	1080 	GLU	E	Protein	S	2
FT	#SUB	291	1121 	LEU	D	246	1076 	PHE	E	Protein	S	1
FT	#SUB	291	1121 	LEU	D	247	1077 	HIS	E	Protein	S	6
FT	#SUB	291	1121 	LEU	D	250	1080 	GLU	E	Protein	S	1
FT	#SUB	295	1125 	GLN	D	246	1076 	PHE	E	Protein	S	1
FT	#HET	25	 855 	LEU	D	3	1201 	0NH	D	A	5
FT	#HET	27	 857 	LYS	D	3	1201 	0NH	D	B	1
FT	#HET	28	 858 	GLY	D	3	1201 	0NH	D	B	1
FT	#HET	33	 863 	VAL	D	3	1201 	0NH	D	S	1
FT	#HET	50	 880 	ALA	D	3	1201 	0NH	D	S	3
FT	#HET	99	 929 	MET	D	3	1201 	0NH	D	S	2
FT	#HET	100	 930 	GLU	D	3	1201 	0NH	D	B	3
FT	#HET	101	 931 	TYR	D	3	1201 	0NH	D	A	5
FT	#HET	102	 932 	LEU	D	3	1201 	0NH	D	A	12
FT	#HET	105	 935 	GLY	D	3	1201 	0NH	D	B	2
FT	#HET	150	 980 	ARG	D	3	1201 	0NH	D	B	2
FT	#HET	151	 981 	ASN	D	3	1201 	0NH	D	S	1
FT	#HET	153	 983 	LEU	D	3	1201 	0NH	D	S	5
FT	#HET	164	 994 	ASP	D	3	1201 	0NH	D	A	4
FT	DISORDER	1	4
CC	SEQUENCE	298 AA (ATOM);
CC	AFEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
CC	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
CC	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
CC	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
CC	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	ATOM   ----AFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	           **********************************************
CC	SEQRES VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	ATOM   VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	       **************************************************
CC	SEQRES YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	ATOM   YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	       **************************************************
CC	SEQRES NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	ATOM   NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	       **************************************************
CC	SEQRES FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	ATOM   FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	       **************************************************
CC	SEQRES LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	ATOM   LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	       **************************************************
CC	SEQRES AG
CC	ATOM   AG
CC	       **
SQ	SEQUENCE	302 AA;      MW;         CN;
	GSSGAFEDRD PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA VKKLQHSTEE
	HLRDFEREIE ILKSLQHDNI VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH
	IKLLQYTSQI CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV LPQDKEYYKV
	KEPGESPIFW YAPESLTESK FSVASDVWSF GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ
	GQMIVFHLIE LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA LRVDQIRDNM
	AG
//
ID	4E4ME	STANDARD;	PRT;	302	AA.
DT	CONVERTED FROM PDB (SEQRES) 4E4M
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.193
FT	#SUB	60	 890 	GLU	E	9	 839 	ARG	A	Protein	S	6
FT	#SUB	64	 894 	ASP	E	9	 839 	ARG	A	Protein	S	8
FT	#SUB	169	 999 	LYS	E	7	 837 	GLU	A	Protein	S	5
FT	#SUB	172	1002 	PRO	E	5	 835 	ALA	A	Protein	S	3
FT	#SUB	175	1005 	LYS	E	5	 835 	ALA	A	Protein	S	2
FT	#SUB	177	1007 	PTR	E	5	 835 	ALA	A	Protein	A	5
FT	#SUB	178	1008 	PTR	E	5	 835 	ALA	A	Protein	A	4
FT	#SUB	178	1008 	PTR	E	7	 837 	GLU	A	Protein	S	17
FT	#SUB	179	1009 	LYS	E	5	 835 	ALA	A	Protein	A	5
FT	#SUB	179	1009 	LYS	E	6	 836 	PHE	A	Protein	A	11
FT	#SUB	179	1009 	LYS	E	7	 837 	GLU	A	Protein	B	4
FT	#SUB	179	1009 	LYS	E	15	 845 	GLU	A	Protein	S	4
FT	#SUB	180	1010 	VAL	E	7	 837 	GLU	A	Protein	B	2
FT	#SUB	181	1011 	LYS	E	6	 836 	PHE	A	Protein	S	1
FT	#SUB	181	1011 	LYS	E	7	 837 	GLU	A	Protein	B	2
FT	#SUB	181	1011 	LYS	E	8	 838 	ASP	A	Protein	S	2
FT	#SUB	181	1011 	LYS	E	9	 839 	ARG	A	Protein	B	4
FT	#SUB	181	1011 	LYS	E	10	 840 	ASP	A	Protein	B	2
FT	#SUB	181	1011 	LYS	E	13	 843 	GLN	A	Protein	S	3
FT	#SUB	181	1011 	LYS	E	15	 845 	GLU	A	Protein	S	1
FT	#SUB	182	1012 	GLU	E	7	 837 	GLU	A	Protein	S	1
FT	#SUB	182	1012 	GLU	E	9	 839 	ARG	A	Protein	S	5
FT	#SUB	182	1012 	GLU	E	10	 840 	ASP	A	Protein	B	2
FT	#SUB	182	1012 	GLU	E	13	 843 	GLN	A	Protein	B	2
FT	#SUB	183	1013 	PRO	E	9	 839 	ARG	A	Protein	S	1
FT	#SUB	183	1013 	PRO	E	10	 840 	ASP	A	Protein	A	4
FT	#SUB	196	1026 	LEU	E	92	 922 	ARG	A	Protein	B	3
FT	#SUB	197	1027 	THR	E	91	 921 	GLY	A	Protein	S	1
FT	#SUB	197	1027 	THR	E	92	 922 	ARG	A	Protein	B	9
FT	#SUB	198	1028 	GLU	E	92	 922 	ARG	A	Protein	B	1
FT	#SUB	199	1029 	SER	E	92	 922 	ARG	A	Protein	A	6
FT	#SUB	238	1068 	ASP	E	59	 889 	GLU	A	Protein	S	2
FT	#SUB	240	1070 	GLN	E	63	 893 	ARG	A	Protein	S	6
FT	#SUB	241	1071 	GLY	E	63	 893 	ARG	A	Protein	B	1
FT	#SUB	241	1071 	GLY	E	66	 896 	GLU	A	Protein	B	2
FT	#SUB	242	1072 	GLN	E	66	 896 	GLU	A	Protein	A	6
FT	#SUB	242	1072 	GLN	E	88	 918 	TYR	A	Protein	S	5
FT	#SUB	243	1073 	MET	E	59	 889 	GLU	A	Protein	S	3
FT	#SUB	243	1073 	MET	E	62	 892 	LEU	A	Protein	S	1
FT	#SUB	246	1076 	PHE	E	62	 892 	LEU	A	Protein	S	2
FT	#SUB	246	1076 	PHE	E	92	 922 	ARG	A	Protein	S	2
FT	#SUB	246	1076 	PHE	E	93	 923 	ARG	A	Protein	A	9
FT	#SUB	246	1076 	PHE	E	94	 924 	ASN	A	Protein	S	6
FT	#SUB	249	1079 	ILE	E	92	 922 	ARG	A	Protein	S	2
FT	#SUB	249	1079 	ILE	E	93	 923 	ARG	A	Protein	S	2
FT	#SUB	250	1080 	GLU	E	93	 923 	ARG	A	Protein	S	5
FT	#SUB	253	1083 	LYS	E	93	 923 	ARG	A	Protein	S	1
FT	#SUB	234	1064 	MET	E	287	1117 	ARG	D	Protein	B	2
FT	#SUB	235	1065 	ILE	E	287	1117 	ARG	D	Protein	B	1
FT	#SUB	246	1076 	PHE	E	291	1121 	LEU	D	Protein	B	1
FT	#SUB	246	1076 	PHE	E	295	1125 	GLN	D	Protein	S	1
FT	#SUB	247	1077 	HIS	E	287	1117 	ARG	D	Protein	A	2
FT	#SUB	247	1077 	HIS	E	288	1118 	ASP	D	Protein	S	1
FT	#SUB	247	1077 	HIS	E	291	1121 	LEU	D	Protein	A	6
FT	#SUB	250	1080 	GLU	E	132	 962 	LYS	D	Protein	S	2
FT	#SUB	250	1080 	GLU	E	135	 965 	GLU	D	Protein	A	10
FT	#SUB	250	1080 	GLU	E	287	1117 	ARG	D	Protein	S	2
FT	#SUB	250	1080 	GLU	E	290	1120 	ALA	D	Protein	S	2
FT	#SUB	250	1080 	GLU	E	291	1121 	LEU	D	Protein	S	1
FT	#SUB	251	1081 	LEU	E	287	1117 	ARG	D	Protein	S	2
FT	#SUB	253	1083 	LYS	E	132	 962 	LYS	D	Protein	S	1
FT	#SUB	254	1084 	ASN	E	77	 907 	HIS	D	Protein	S	2
FT	#SUB	254	1084 	ASN	E	132	 962 	LYS	D	Protein	S	4
FT	#SUB	254	1084 	ASN	E	135	 965 	GLU	D	Protein	S	8
FT	#SUB	254	1084 	ASN	E	136	 966 	TYR	D	Protein	B	1
FT	#SUB	254	1084 	ASN	E	139	 969 	THR	D	Protein	B	1
FT	#SUB	255	1085 	ASN	E	136	 966 	TYR	D	Protein	S	4
FT	#SUB	255	1085 	ASN	E	139	 969 	THR	D	Protein	A	8
FT	#SUB	255	1085 	ASN	E	140	 970 	LYS	D	Protein	S	1
FT	#SUB	256	1086 	GLY	E	139	 969 	THR	D	Protein	B	1
FT	#HET	25	 855 	LEU	E	4	1201 	0NH	E	A	4
FT	#HET	26	 856 	GLY	E	4	1201 	0NH	E	B	2
FT	#HET	27	 857 	LYS	E	4	1201 	0NH	E	B	2
FT	#HET	28	 858 	GLY	E	4	1201 	0NH	E	B	2
FT	#HET	33	 863 	VAL	E	4	1201 	0NH	E	S	3
FT	#HET	50	 880 	ALA	E	4	1201 	0NH	E	S	3
FT	#HET	99	 929 	MET	E	4	1201 	0NH	E	S	1
FT	#HET	100	 930 	GLU	E	4	1201 	0NH	E	B	2
FT	#HET	101	 931 	TYR	E	4	1201 	0NH	E	A	5
FT	#HET	102	 932 	LEU	E	4	1201 	0NH	E	B	9
FT	#HET	105	 935 	GLY	E	4	1201 	0NH	E	B	3
FT	#HET	150	 980 	ARG	E	4	1201 	0NH	E	B	1
FT	#HET	151	 981 	ASN	E	4	1201 	0NH	E	S	1
FT	#HET	153	 983 	LEU	E	4	1201 	0NH	E	S	5
FT	#HET	164	 994 	ASP	E	4	1201 	0NH	E	A	7
FT	DISORDER	1	4
CC	SEQUENCE	298 AA (ATOM);
CC	AFEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
CC	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
CC	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
CC	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
CC	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSSGAFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	ATOM   ----AFEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVA
CC	           **********************************************
CC	SEQRES VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	ATOM   VKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIME
CC	       **************************************************
CC	SEQRES YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	ATOM   YLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATR
CC	       **************************************************
CC	SEQRES NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	ATOM   NILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESK
CC	       **************************************************
CC	SEQRES FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	ATOM   FSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
CC	       **************************************************
CC	SEQRES LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	ATOM   LLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNM
CC	       **************************************************
CC	SEQRES AG
CC	ATOM   AG
CC	       **
SQ	SEQUENCE	302 AA;      MW;         CN;
	GSSGAFEDRD PTQFEERHLK FLQQLGKGNF GSVEMCRYDP LQDNTGEVVA VKKLQHSTEE
	HLRDFEREIE ILKSLQHDNI VKYKGVCYSA GRRNLKLIME YLPYGSLRDY LQKHKERIDH
	IKLLQYTSQI CKGMEYLGTK RYIHRDLATR NILVENENRV KIGDFGLTKV LPQDKEYYKV
	KEPGESPIFW YAPESLTESK FSVASDVWSF GVVLYELFTY IEKSKSPPAE FMRMIGNDKQ
	GQMIVFHLIE LLKNNGRLPR PDGCPDEIYM IMTECWNNNV NQRPSFRDLA LRVDQIRDNM
	AG
//