ID	4DPIA	STANDARD;	PRT;	391	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DPI
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.174
FT	#HET	17	  59 	GLY	A	1	501 	0N1	A	B	8
FT	#HET	18	  60 	GLN	A	1	501 	0N1	A	B	12
FT	#HET	19	  61 	GLY	A	1	501 	0N1	A	B	11
FT	#HET	36	  78 	LEU	A	1	501 	0N1	A	S	3
FT	#HET	38	  80 	ASP	A	1	501 	0N1	A	S	14
FT	#HET	40	  82 	GLY	A	1	501 	0N1	A	B	16
FT	#HET	41	  83 	SER	A	1	501 	0N1	A	S	4
FT	#HET	75	 117 	VAL	A	1	501 	0N1	A	S	1
FT	#HET	76	 118 	PRO	A	1	501 	0N1	A	B	3
FT	#HET	77	 119 	TYR	A	1	501 	0N1	A	A	20
FT	#HET	78	 120 	THR	A	1	501 	0N1	A	A	16
FT	#HET	79	 121 	GLN	A	1	501 	0N1	A	A	29
FT	#HET	116	 158 	ILE	A	1	501 	0N1	A	S	3
FT	#HET	124	 166 	ILE	A	1	501 	0N1	A	S	4
FT	#HET	132	 174 	ILE	A	1	501 	0N1	A	A	5
FT	#HET	134	 176 	ARG	A	1	501 	0N1	A	S	7
FT	#HET	204	 246 	TYR	A	1	501 	0N1	A	S	13
FT	#HET	234	 276 	ASP	A	1	501 	0N1	A	S	11
FT	#HET	235	 277 	SER	A	1	501 	0N1	A	B	3
FT	#HET	236	 278 	GLY	A	1	501 	0N1	A	B	31
FT	#HET	237	 279 	THR	A	1	501 	0N1	A	A	24
FT	#HET	238	 280 	THR	A	1	501 	0N1	A	A	26
FT	#HET	241	 283 	ARG	A	1	501 	0N1	A	S	3
FT	#HET	341	 383 	ALA	A	1	501 	0N1	A	S	3
FT	DISORDER	1	4
FT	DISORDER	163	175
FT	DISORDER	367	367
CC	SEQUENCE	373 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGVG GSMIIGGIDH SLYTGSLWYT
CC	PIRREWYYEV IIVRVEINGQ DLKMDCKEYN YDKSIVDSGT TNLRLPKKVF EAAVKSIKAA
CC	SSTEKFPDGF WLGEQLVCWQ AGTTPWNIFP VISLYLMGEV TNQSFRITIL PQQYLRPVED
CC	VATSQDDCYK FAISQSSTGT VMGAVIMEGF YVVFDRARKR IGFAVSACHH DEFRTAAVEG
CC	PFVTLDMEDC GYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	ATOM   ----FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	           **********************************************
CC	SEQRES HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	ATOM   HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	       **************************************************
CC	SEQRES VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	ATOM   VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	       **************************************************
CC	SEQRES HVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIR
CC	ATOM   HVPNLFSLQLCG-------------VGGSMIIGGIDHSLYTGSLWYTPIR
CC	       ************             *************************
CC	SEQRES REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	ATOM   REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	       **************************************************
CC	SEQRES VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	ATOM   VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	       **************************************************
CC	SEQRES SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	ATOM   SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	       **************************************************
CC	SEQRES FDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN
CC	ATOM   FDRARKRIGFAVSACH-HDEFRTAAVEGPFVTLDMEDCGYN
CC	       **************** ************************
SQ	SEQUENCE	391 AA;      MW;         CN;
	MRGSFVEMVD NLRGKSGQGY YVEMTVGSPP QTLNILVDTG SSNFAVGAAP HPFLHRYYQR
	QLSSTYRDLR KGVYVPYTQG KWEGELGTDL VSIPHGPNVT VRANIAAITE SDKFFINGSN
	WEGILGLAYA EIARPDDSLE PFFDSLVKQT HVPNLFSLQL CGAGFPLNQS EVLASVGGSM
	IIGGIDHSLY TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK SIVDSGTTNL
	RLPKKVFEAA VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS LYLMGEVTNQ
	SFRITILPQQ YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV FDRARKRIGF
	AVSACHVHDE FRTAAVEGPF VTLDMEDCGY N
//