ID	4DPFA	STANDARD;	PRT;	391	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DPF
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.800
CC	R-Factor	0.194
FT	#HET	17	  59 	GLY	A	1	500 	0LG	A	B	5
FT	#HET	18	  60 	GLN	A	1	500 	0LG	A	A	7
FT	#HET	36	  78 	LEU	A	1	500 	0LG	A	S	2
FT	#HET	38	  80 	ASP	A	1	500 	0LG	A	S	6
FT	#HET	40	  82 	GLY	A	1	500 	0LG	A	B	8
FT	#HET	41	  83 	SER	A	1	500 	0LG	A	S	2
FT	#HET	75	 117 	VAL	A	1	500 	0LG	A	S	1
FT	#HET	76	 118 	PRO	A	1	500 	0LG	A	B	2
FT	#HET	77	 119 	TYR	A	1	500 	0LG	A	A	9
FT	#HET	78	 120 	THR	A	1	500 	0LG	A	A	9
FT	#HET	79	 121 	GLN	A	1	500 	0LG	A	A	15
FT	#HET	116	 158 	ILE	A	1	500 	0LG	A	S	5
FT	#HET	124	 166 	ILE	A	1	500 	0LG	A	S	2
FT	#HET	132	 174 	ILE	A	1	500 	0LG	A	A	3
FT	#HET	204	 246 	TYR	A	1	500 	0LG	A	S	6
FT	#HET	234	 276 	ASP	A	1	500 	0LG	A	S	7
FT	#HET	236	 278 	GLY	A	1	500 	0LG	A	B	12
FT	#HET	237	 279 	THR	A	1	500 	0LG	A	A	10
FT	#HET	238	 280 	THR	A	1	500 	0LG	A	A	9
FT	#HET	239	 281 	ASN	A	1	500 	0LG	A	A	12
FT	#HET	241	 283 	ARG	A	1	500 	0LG	A	S	3
FT	#HET	331	 373 	SER	A	1	500 	0LG	A	S	1
FT	DISORDER	1	4
FT	DISORDER	164	175
CC	SEQUENCE	375 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAV GGSMIIGGID HSLYTGSLWY
CC	TPIRREWYYE VIIVRVEING QDLKMDCKEY NYDKSIVDSG TTNLRLPKKV FEAAVKSIKA
CC	ASSTEKFPDG FWLGEQLVCW QAGTTPWNIF PVISLYLMGE VTNQSFRITI LPQQYLRPVE
CC	DVATSQDDCY KFAISQSSTG TVMGAVIMEG FYVVFDRARK RIGFAVSACH VHDEFRTAAV
CC	EGPFVTLDME DCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	ATOM   ----FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAP
CC	           **********************************************
CC	SEQRES HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	ATOM   HPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVT
CC	       **************************************************
CC	SEQRES VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	ATOM   VRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQT
CC	       **************************************************
CC	SEQRES HVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIR
CC	ATOM   HVPNLFSLQLCGA------------VGGSMIIGGIDHSLYTGSLWYTPIR
CC	       *************            *************************
CC	SEQRES REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	ATOM   REWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAA
CC	       **************************************************
CC	SEQRES VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	ATOM   VKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQ
CC	       **************************************************
CC	SEQRES SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	ATOM   SFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVV
CC	       **************************************************
CC	SEQRES FDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN
CC	ATOM   FDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYN
CC	       *****************************************
SQ	SEQUENCE	391 AA;      MW;         CN;
	MRGSFVEMVD NLRGKSGQGY YVEMTVGSPP QTLNILVDTG SSNFAVGAAP HPFLHRYYQR
	QLSSTYRDLR KGVYVPYTQG KWEGELGTDL VSIPHGPNVT VRANIAAITE SDKFFINGSN
	WEGILGLAYA EIARPDDSLE PFFDSLVKQT HVPNLFSLQL CGAGFPLNQS EVLASVGGSM
	IIGGIDHSLY TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK SIVDSGTTNL
	RLPKKVFEAA VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS LYLMGEVTNQ
	SFRITILPQQ YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV FDRARKRIGF
	AVSACHVHDE FRTAAVEGPF VTLDMEDCGY N
//