ID	4DJYA	STANDARD;	PRT;	414	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DJY
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.860
CC	R-Factor	0.182
FT	#SUB	260	 300 	LYS	A	127	 167 	ASP	B	Protein	S	7
FT	#SUB	263	 303 	GLU	A	125	 165 	GLU	B	Protein	S	9
FT	#SUB	267	 307 	LYS	A	89	 129 	TYR	B	Protein	S	11
FT	#SUB	267	 307 	LYS	A	98	 138 	GLU	B	Protein	S	5
FT	#HET	28	  68 	ARG	A	2	502 	TLA	A	S	6
FT	#HET	31	  71 	SER	A	1	501 	0KR	A	B	3
FT	#HET	32	  72 	GLY	A	1	501 	0KR	A	B	2
FT	#HET	33	  73 	GLN	A	1	501 	0KR	A	B	5
FT	#HET	34	  74 	GLY	A	1	501 	0KR	A	B	7
FT	#HET	49	  89 	ASN	A	2	502 	TLA	A	S	3
FT	#HET	51	  91 	LEU	A	1	501 	0KR	A	S	2
FT	#HET	53	  93 	ASP	A	1	501 	0KR	A	S	11
FT	#HET	55	  95 	GLY	A	1	501 	0KR	A	B	1
FT	#HET	56	  96 	SER	A	1	501 	0KR	A	S	3
FT	#HET	70	 110 	HIS	A	2	502 	TLA	A	S	7
FT	#HET	71	 111 	ARG	A	2	502 	TLA	A	S	10
FT	#HET	92	 132 	TYR	A	1	501 	0KR	A	S	8
FT	#HET	129	 169 	PHE	A	1	501 	0KR	A	A	5
FT	#HET	131	 171 	ILE	A	1	501 	0KR	A	S	1
FT	#HET	135	 175 	ASN	A	2	502 	TLA	A	S	4
FT	#HET	136	 176 	TRP	A	1	501 	0KR	A	S	2
FT	#HET	139	 179 	ILE	A	1	501 	0KR	A	S	2
FT	#HET	249	 289 	ASP	A	1	501 	0KR	A	S	5
FT	#HET	250	 290 	SER	A	1	501 	0KR	A	B	2
FT	#HET	251	 291 	GLY	A	1	501 	0KR	A	B	15
FT	#HET	252	 292 	THR	A	1	501 	0KR	A	A	6
FT	#HET	253	 293 	THR	A	1	501 	0KR	A	A	4
FT	#HET	356	 396 	ALA	A	1	501 	0KR	A	S	1
FT	DISORDER	1	17
FT	DISORDER	408	414
CC	SEQUENCE	390 AA (ATOM);
CC	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
CC	SSTYRDLRKG VYVPYTQGKW EGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
CC	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG AGFPLNQSEV LASVGGSMII
CC	GGIDHSLYTG SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL
CC	PKKVFEAAVK SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF
CC	RITILPQQYL RPVEDVATSQ DDCYKFAISQ SSTGTVMGAV IMEGFYVVFD RARKRIGFAV
CC	SACHVHDEFR TAAVEGPFVT LDMEDCGYNI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES LRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNI
CC	ATOM   -----------------GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNI
CC	                        *********************************
CC	SEQRES LVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGE
CC	ATOM   LVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGE
CC	       **************************************************
CC	SEQRES LGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP
CC	ATOM   LGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP
CC	       **************************************************
CC	SEQRES DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
CC	ATOM   DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
CC	       **************************************************
CC	SEQRES DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDS
CC	ATOM   DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDS
CC	       **************************************************
CC	SEQRES GTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI
CC	ATOM   GTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI
CC	       **************************************************
CC	SEQRES FPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSST
CC	ATOM   FPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSST
CC	       **************************************************
CC	SEQRES GTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDM
CC	ATOM   GTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDM
CC	       **************************************************
CC	SEQRES EDCGYNIPQTDEST
CC	ATOM   EDCGYNI-------
CC	       *******       
SQ	SEQUENCE	414 AA;      MW;         CN;
	LRLPRETDEE PEEPGRRGSF VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA
	VGAAPHPFLH RYYQRQLSST YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI
	AAITESDKFF INGSNWEGIL GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGF
	PLNQSEVLAS VGGSMIIGGI DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE
	YNYDKSIVDS GTTNLRLPKK VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI
	FPVISLYLMG EVTNQSFRIT ILPQQYLRPV EDVATSQDDC YKFAISQSST GTVMGAVIME
	GFYVVFDRAR KRIGFAVSAC HVHDEFRTAA VEGPFVTLDM EDCGYNIPQT DEST
//
ID	4DJYB	STANDARD;	PRT;	414	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DJY
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.860
CC	R-Factor	0.182
FT	#SUB	89	 129 	TYR	B	267	 307 	LYS	A	Protein	S	11
FT	#SUB	98	 138 	GLU	B	267	 307 	LYS	A	Protein	S	5
FT	#SUB	125	 165 	GLU	B	263	 303 	GLU	A	Protein	S	9
FT	#SUB	127	 167 	ASP	B	260	 300 	LYS	A	Protein	S	7
FT	#HET	28	  68 	ARG	B	4	502 	TLA	B	S	6
FT	#HET	31	  71 	SER	B	3	501 	0KR	B	B	3
FT	#HET	32	  72 	GLY	B	3	501 	0KR	B	B	2
FT	#HET	33	  73 	GLN	B	3	501 	0KR	B	B	3
FT	#HET	34	  74 	GLY	B	3	501 	0KR	B	B	7
FT	#HET	49	  89 	ASN	B	4	502 	TLA	B	S	3
FT	#HET	51	  91 	LEU	B	3	501 	0KR	B	S	2
FT	#HET	53	  93 	ASP	B	3	501 	0KR	B	S	11
FT	#HET	55	  95 	GLY	B	3	501 	0KR	B	B	2
FT	#HET	56	  96 	SER	B	3	501 	0KR	B	S	3
FT	#HET	70	 110 	HIS	B	4	502 	TLA	B	S	7
FT	#HET	71	 111 	ARG	B	4	502 	TLA	B	S	9
FT	#HET	92	 132 	TYR	B	3	501 	0KR	B	S	2
FT	#HET	94	 134 	GLN	B	3	501 	0KR	B	S	1
FT	#HET	129	 169 	PHE	B	3	501 	0KR	B	A	6
FT	#HET	131	 171 	ILE	B	3	501 	0KR	B	S	2
FT	#HET	135	 175 	ASN	B	4	502 	TLA	B	S	6
FT	#HET	136	 176 	TRP	B	3	501 	0KR	B	S	3
FT	#HET	139	 179 	ILE	B	3	501 	0KR	B	S	1
FT	#HET	249	 289 	ASP	B	3	501 	0KR	B	S	5
FT	#HET	250	 290 	SER	B	3	501 	0KR	B	B	2
FT	#HET	251	 291 	GLY	B	3	501 	0KR	B	B	15
FT	#HET	252	 292 	THR	B	3	501 	0KR	B	A	5
FT	#HET	253	 293 	THR	B	3	501 	0KR	B	A	4
FT	#HET	356	 396 	ALA	B	3	501 	0KR	B	S	1
FT	DISORDER	1	17
FT	DISORDER	407	414
CC	SEQUENCE	389 AA (ATOM);
CC	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
CC	SSTYRDLRKG VYVPYTQGKW EGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
CC	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG AGFPLNQSEV LASVGGSMII
CC	GGIDHSLYTG SLWYTPIRRE WYYEVIIVRV EINGQDLKMD CKEYNYDKSI VDSGTTNLRL
CC	PKKVFEAAVK SIKAASSTEK FPDGFWLGEQ LVCWQAGTTP WNIFPVISLY LMGEVTNQSF
CC	RITILPQQYL RPVEDVATSQ DDCYKFAISQ SSTGTVMGAV IMEGFYVVFD RARKRIGFAV
CC	SACHVHDEFR TAAVEGPFVT LDMEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES LRLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNI
CC	ATOM   -----------------GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNI
CC	                        *********************************
CC	SEQRES LVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGE
CC	ATOM   LVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGE
CC	       **************************************************
CC	SEQRES LGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP
CC	ATOM   LGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARP
CC	       **************************************************
CC	SEQRES DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
CC	ATOM   DDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGI
CC	       **************************************************
CC	SEQRES DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDS
CC	ATOM   DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDS
CC	       **************************************************
CC	SEQRES GTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI
CC	ATOM   GTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNI
CC	       **************************************************
CC	SEQRES FPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSST
CC	ATOM   FPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSST
CC	       **************************************************
CC	SEQRES GTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDM
CC	ATOM   GTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDM
CC	       **************************************************
CC	SEQRES EDCGYNIPQTDEST
CC	ATOM   EDCGYN--------
CC	       ******        
SQ	SEQUENCE	414 AA;      MW;         CN;
	LRLPRETDEE PEEPGRRGSF VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA
	VGAAPHPFLH RYYQRQLSST YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPNVTVRANI
	AAITESDKFF INGSNWEGIL GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGF
	PLNQSEVLAS VGGSMIIGGI DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE
	YNYDKSIVDS GTTNLRLPKK VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI
	FPVISLYLMG EVTNQSFRIT ILPQQYLRPV EDVATSQDDC YKFAISQSST GTVMGAVIME
	GFYVVFDRAR KRIGFAVSAC HVHDEFRTAA VEGPFVTLDM EDCGYNIPQT DEST
//