ID	4DFNA	STANDARD;	PRT;	274	AA.
DT	CONVERTED FROM PDB (SEQRES) 4DFN
DE	Tyrosine-protein kinase SYK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.480
CC	R-Factor	0.222
FT	#HET	15	 377 	LEU	A	1	701 	0K1	A	A	7
FT	#HET	16	 378 	GLY	A	1	701 	0K1	A	B	2
FT	#HET	20	 382 	PHE	A	1	701 	0K1	A	S	5
FT	#HET	23	 385 	VAL	A	1	701 	0K1	A	S	2
FT	#HET	38	 400 	ALA	A	1	701 	0K1	A	S	5
FT	#HET	71	 433 	VAL	A	1	701 	0K1	A	S	1
FT	#HET	86	 448 	MET	A	1	701 	0K1	A	S	4
FT	#HET	87	 449 	GLU	A	1	701 	0K1	A	B	3
FT	#HET	88	 450 	MET	A	1	701 	0K1	A	A	3
FT	#HET	89	 451 	ALA	A	1	701 	0K1	A	A	11
FT	#HET	92	 454 	GLY	A	1	701 	0K1	A	B	2
FT	#HET	93	 455 	PRO	A	1	701 	0K1	A	S	5
FT	#HET	96	 458 	LYS	A	1	701 	0K1	A	S	5
FT	#HET	139	 501 	LEU	A	1	701 	0K1	A	S	7
FT	#HET	149	 511 	SER	A	1	701 	0K1	A	S	2
FT	#HET	150	 512 	ASP	A	1	701 	0K1	A	A	4
FT	DISORDER	44	48
CC	SEQUENCE	269 AA (ATOM);
CC	VYLDRKLLTL EDKELGSGNF GTVKKGYYQM KKVVKTVAVK ILKPALKDEL LAEANVMQQL
CC	DNPYIVRMIG ICEAESWMLV MEMAELGPLN KYLQQNRHVK DKNIIELVHQ VSMGMKYLEE
CC	SNFVHRDLAA RNVLLVTQHY AKISDFGLSK ALRADENYYK AQTHGKWPVK WYAPECINYY
CC	KFSSKSDVWS FGVLMWEAFS YGQKPYRGMK GSEVTAMLEK GERMGCPAGC PREMYDLMNL
CC	CWTYDVENRP GFAAVELRLR NYYYDVVNE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPA
CC	ATOM   VYLDRKLLTLEDKELGSGNFGTVKKGYYQMKKVVKTVAVKILK-----PA
CC	       *******************************************     **
CC	SEQRES LKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQ
CC	ATOM   LKDELLAEANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQ
CC	       **************************************************
CC	SEQRES NRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD
CC	ATOM   NRHVKDKNIIELVHQVSMGMKYLEESNFVHRDLAARNVLLVTQHYAKISD
CC	       **************************************************
CC	SEQRES FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
CC	ATOM   FGLSKALRADENYYKAQTHGKWPVKWYAPECINYYKFSSKSDVWSFGVLM
CC	       **************************************************
CC	SEQRES WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYD
CC	ATOM   WEAFSYGQKPYRGMKGSEVTAMLEKGERMGCPAGCPREMYDLMNLCWTYD
CC	       **************************************************
CC	SEQRES VENRPGFAAVELRLRNYYYDVVNE
CC	ATOM   VENRPGFAAVELRLRNYYYDVVNE
CC	       ************************
SQ	SEQUENCE	274 AA;      MW;         CN;
	VYLDRKLLTL EDKELGSGNF GTVKKGYYQM KKVVKTVAVK ILKNEANDPA LKDELLAEAN
	VMQQLDNPYI VRMIGICEAE SWMLVMEMAE LGPLNKYLQQ NRHVKDKNII ELVHQVSMGM
	KYLEESNFVH RDLAARNVLL VTQHYAKISD FGLSKALRAD ENYYKAQTHG KWPVKWYAPE
	CINYYKFSSK SDVWSFGVLM WEAFSYGQKP YRGMKGSEVT AMLEKGERMG CPAGCPREMY
	DLMNLCWTYD VENRPGFAAV ELRLRNYYYD VVNE
//