ID	4CQFA	STANDARD;	PRT;	446	AA.
DT	CONVERTED FROM PDB (SEQRES) 4CQF
DE	HISTONE DEACETYLASE 8
OS	SCHISTOSOMA MANSONI
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.192
FT	#SUB	10	  10 	GLN	A	218	 218 	GLY	B	Protein	S	2
FT	#SUB	10	  10 	GLN	A	219	 219 	THR	B	Protein	S	2
FT	#SUB	39	  39 	PRO	A	90	  90 	LEU	B	Protein	B	1
FT	#SUB	40	  40 	GLU	A	90	  90 	LEU	B	Protein	B	2
FT	#SUB	41	  41 	LEU	A	90	  90 	LEU	B	Protein	B	2
FT	#SUB	42	  42 	SER	A	90	  90 	LEU	B	Protein	B	1
FT	#SUB	42	  42 	SER	A	93	  93 	ASP	B	Protein	S	4
FT	#SUB	43	  43 	ARG	A	96	  96 	SER	B	Protein	S	1
FT	#SUB	43	  43 	ARG	A	147	 147 	GLU	B	Protein	S	2
FT	#SUB	45	  45 	PRO	A	99	  99 	TYR	B	Protein	S	1
FT	#SUB	48	  48 	GLN	A	214	 214 	GLY	B	Protein	A	4
FT	#SUB	48	  48 	GLN	A	216	 216 	PHE	B	Protein	S	6
FT	#SUB	48	  48 	GLN	A	217	 217 	PRO	B	Protein	S	3
FT	#SUB	49	  49 	TRP	A	214	 214 	GLY	B	Protein	A	5
FT	#SUB	49	  49 	TRP	A	215	 215 	PHE	B	Protein	B	1
FT	#SUB	50	  50 	ASP	A	215	 215 	PHE	B	Protein	B	2
FT	#SUB	50	  50 	ASP	A	292	 292 	HIS	B	Protein	A	8
FT	#SUB	50	  50 	ASP	A	294	 294 	ILE	B	Protein	B	1
FT	#SUB	51	  51 	SER	A	292	 292 	HIS	B	Protein	S	1
FT	#SUB	51	  51 	SER	A	294	 294 	ILE	B	Protein	A	2
FT	#SUB	52	  52 	PRO	A	210	 210 	HIS	B	Protein	S	2
FT	#SUB	52	  52 	PRO	A	212	 212 	SER	B	Protein	S	1
FT	#SUB	52	  52 	PRO	A	251	 251 	GLU	B	Protein	S	5
FT	#SUB	55	  55 	MET	A	213	 213 	PRO	B	Protein	S	2
FT	#SUB	72	  72 	LYS	A	213	 213 	PRO	B	Protein	S	3
FT	#SUB	79	  79 	CYS	A	231	 231 	PRO	B	Protein	A	3
FT	#SUB	108	 108 	PHE	A	213	 213 	PRO	B	Protein	S	4
FT	#SUB	109	 109 	ASP	A	213	 213 	PRO	B	Protein	S	2
FT	#SUB	112	 112 	LEU	A	213	 213 	PRO	B	Protein	S	3
FT	#SUB	112	 112 	LEU	A	214	 214 	GLY	B	Protein	S	2
FT	#SUB	116	 116 	GLN	A	214	 214 	GLY	B	Protein	S	1
FT	#SUB	124	 124 	ALA	A	99	  99 	TYR	B	Protein	S	1
FT	#SUB	129	 129 	HIS	A	89	  89 	GLU	B	Protein	S	2
FT	#SUB	129	 129 	HIS	A	93	  93 	ASP	B	Protein	S	5
FT	#SUB	129	 129 	HIS	A	99	  99 	TYR	B	Protein	S	1
FT	#SUB	362	 362 	LYS	A	90	  90 	LEU	B	Protein	S	1
FT	#SUB	199	 199 	TYR	A	393	 393 	PRO	C	Protein	S	3
FT	#SUB	199	 199 	TYR	A	394	 394 	HIS	C	Protein	S	7
FT	#SUB	201	 201 	PRO	A	392	 392 	PHE	C	Protein	S	3
FT	#SUB	202	 202 	ARG	A	392	 392 	PHE	C	Protein	S	1
FT	#SUB	236	 236 	GLY	A	312	 312 	SER	C	Protein	B	1
FT	#SUB	237	 237 	ALA	A	312	 312 	SER	C	Protein	A	3
FT	#SUB	238	 238 	GLY	A	312	 312 	SER	C	Protein	B	1
FT	#SUB	238	 238 	GLY	A	314	 314 	CYS	C	Protein	B	3
FT	#SUB	239	 239 	ARG	A	300	 300 	PHE	C	Protein	S	3
FT	#SUB	239	 239 	ARG	A	314	 314 	CYS	C	Protein	A	2
FT	#SUB	239	 239 	ARG	A	389	 389 	ILE	C	Protein	S	1
FT	#SUB	239	 239 	ARG	A	391	 391 	TYR	C	Protein	S	6
FT	#SUB	239	 239 	ARG	A	392	 392 	PHE	C	Protein	S	3
FT	#SUB	241	 241 	ARG	A	312	 312 	SER	C	Protein	S	2
FT	#SUB	241	 241 	ARG	A	313	 313 	GLU	C	Protein	S	2
FT	#HET	18	  18 	SER	A	5	800 	DMF	A	S	4
FT	#HET	19	  19 	PRO	A	5	800 	DMF	A	A	3
FT	#HET	20	  20 	LYS	A	5	800 	DMF	A	A	6
FT	#HET	21	  21 	PHE	A	5	800 	DMF	A	S	2
FT	#HET	99	  99 	TYR	A	4	700 	9Z8	A	A	9
FT	#HET	100	 100 	ASP	A	4	700 	9Z8	A	A	18
FT	#HET	100	 100 	ASP	A	5	800 	DMF	A	B	1
FT	#HET	104	 104 	PHE	A	5	800 	DMF	A	S	4
FT	#HET	110	 110 	TYR	A	5	800 	DMF	A	S	3
FT	#HET	141	 141 	HIS	A	4	700 	9Z8	A	S	1
FT	#HET	142	 142 	HIS	A	4	700 	9Z8	A	S	4
FT	#HET	150	 150 	GLY	A	4	700 	9Z8	A	B	3
FT	#HET	151	 151 	PHE	A	4	700 	9Z8	A	S	9
FT	#HET	151	 151 	PHE	A	5	800 	DMF	A	A	6
FT	#HET	153	 153 	TYR	A	5	800 	DMF	A	S	7
FT	#HET	184	 184 	ASP	A	3	601 	K	A	A	5
FT	#HET	185	 185 	LEU	A	3	601 	K	A	B	1
FT	#HET	186	 186 	ASP	A	1	500 	ZN	A	S	3
FT	#HET	186	 186 	ASP	A	3	601 	K	A	A	5
FT	#HET	186	 186 	ASP	A	4	700 	9Z8	A	S	3
FT	#HET	188	 188 	HIS	A	1	500 	ZN	A	A	5
FT	#HET	188	 188 	HIS	A	3	601 	K	A	B	2
FT	#HET	188	 188 	HIS	A	4	700 	9Z8	A	S	12
FT	#HET	197	 197 	PHE	A	2	600 	K	A	A	3
FT	#HET	200	 200 	SER	A	2	600 	K	A	B	2
FT	#HET	203	 203 	VAL	A	2	600 	K	A	B	2
FT	#HET	207	 207 	SER	A	3	601 	K	A	S	1
FT	#HET	208	 208 	VAL	A	3	601 	K	A	B	2
FT	#HET	209	 209 	HIS	A	3	601 	K	A	S	1
FT	#HET	216	 216 	PHE	A	4	700 	9Z8	A	S	7
FT	#HET	243	 243 	SER	A	2	600 	K	A	A	4
FT	#HET	285	 285 	ASP	A	1	500 	ZN	A	S	3
FT	#HET	285	 285 	ASP	A	4	700 	9Z8	A	S	2
FT	#HET	301	 301 	TYR	A	6	801 	DMF	A	S	3
FT	#HET	339	 339 	GLY	A	4	700 	9Z8	A	B	2
FT	#HET	341	 341 	TYR	A	4	700 	9Z8	A	S	6
FT	#HET	352	 352 	ARG	A	6	801 	DMF	A	B	1
FT	#HET	355	 355 	ALA	A	6	801 	DMF	A	B	1
FT	#HET	356	 356 	LEU	A	6	801 	DMF	A	B	2
FT	#HET	359	 359 	GLU	A	6	801 	DMF	A	S	3
FT	#HET	366	 366 	MET	A	6	801 	DMF	A	B	3
FT	#HET	368	 368 	ILE	A	6	801 	DMF	A	S	3
FT	DISORDER	1	1
FT	DISORDER	168	176
FT	DISORDER	225	231
FT	DISORDER	303	314
FT	DISORDER	394	401
FT	DISORDER	436	446
CC	SEQUENCE	398 AA (ATOM);
CC	SVGIVYGDQY RQLCCSSPKF GDRYALVMDL INAYKLIPEL SRVPPLQWDS PSRMYEAVTA
CC	FHSTEYVDAL KKLQMLHCEE KELTADDELL MDSFSLNYDC PGFPSVFDYS LAAVQGSLAA
CC	ASALICRHCE VVINWGGGWH HAKRSEASGF CYLNDIVLAI HRLVSSQTRV LYVDLDLHHG
CC	DGVEEAFWYS PRVVTFSVHH ASPGFFPGTG TWNMIFLNGA GRGRFSAFNL PLEEGINDLD
CC	WSNAIGPILD SLNIVIQPSY VVVQCGADCL ATDPHRIFRL TNFYPSLSGY LYAIKKILSW
CC	KVPTLILGGG GYNFPDTARL WTRVTALTIE EVKGKKMTIS PEIPEHSYFS RYGPDFELDI
CC	DYFPDSIQKH HRRILEQLRN YADLNKLIYD YDQVYQLY
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	ATOM   -SVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	        *************************************************
CC	SEQRES SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	ATOM   SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	       **************************************************
CC	SEQRES CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	ATOM   CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	       **************************************************
CC	SEQRES FCYLNDIVLAIHRLVSSTPPETSPNRQTRVLYVDLDLHHGDGVEEAFWYS
CC	ATOM   FCYLNDIVLAIHRLVSS---------QTRVLYVDLDLHHGDGVEEAFWYS
CC	       *****************         ************************
CC	SEQRES PRVVTFSVHHASPGFFPGTGTWNMVDNDKLPIFLNGAGRGRFSAFNLPLE
CC	ATOM   PRVVTFSVHHASPGFFPGTGTWNM-------IFLNGAGRGRFSAFNLPLE
CC	       ************************       *******************
CC	SEQRES EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	ATOM   EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	       **************************************************
CC	SEQRES YPNLNLDSDCDSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	ATOM   YP------------SLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	       **            ************************************
CC	SEQRES TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPHESHNKT
CC	ATOM   TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFP-------
CC	       *******************************************       
CC	SEQRES LDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	ATOM   -DSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLY-----------
CC	        **********************************           
SQ	SEQUENCE	446 AA;      MW;         CN;
	MSVGIVYGDQ YRQLCCSSPK FGDRYALVMD LINAYKLIPE LSRVPPLQWD SPSRMYEAVT
	AFHSTEYVDA LKKLQMLHCE EKELTADDEL LMDSFSLNYD CPGFPSVFDY SLAAVQGSLA
	AASALICRHC EVVINWGGGW HHAKRSEASG FCYLNDIVLA IHRLVSSTPP ETSPNRQTRV
	LYVDLDLHHG DGVEEAFWYS PRVVTFSVHH ASPGFFPGTG TWNMVDNDKL PIFLNGAGRG
	RFSAFNLPLE EGINDLDWSN AIGPILDSLN IVIQPSYVVV QCGADCLATD PHRIFRLTNF
	YPNLNLDSDC DSECSLSGYL YAIKKILSWK VPTLILGGGG YNFPDTARLW TRVTALTIEE
	VKGKKMTISP EIPEHSYFSR YGPDFELDID YFPHESHNKT LDSIQKHHRR ILEQLRNYAD
	LNKLIYDYDQ VYQLYNLTGM GSLVPR
//
ID	4CQFB	STANDARD;	PRT;	446	AA.
DT	CONVERTED FROM PDB (SEQRES) 4CQF
DE	HISTONE DEACETYLASE 8
OS	SCHISTOSOMA MANSONI
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.192
FT	#SUB	89	  89 	GLU	B	129	 129 	HIS	A	Protein	S	2
FT	#SUB	90	  90 	LEU	B	39	  39 	PRO	A	Protein	S	1
FT	#SUB	90	  90 	LEU	B	40	  40 	GLU	A	Protein	S	2
FT	#SUB	90	  90 	LEU	B	41	  41 	LEU	A	Protein	S	2
FT	#SUB	90	  90 	LEU	B	42	  42 	SER	A	Protein	S	1
FT	#SUB	90	  90 	LEU	B	362	 362 	LYS	A	Protein	S	1
FT	#SUB	93	  93 	ASP	B	42	  42 	SER	A	Protein	S	4
FT	#SUB	93	  93 	ASP	B	129	 129 	HIS	A	Protein	S	5
FT	#SUB	96	  96 	SER	B	43	  43 	ARG	A	Protein	S	1
FT	#SUB	99	  99 	TYR	B	45	  45 	PRO	A	Protein	S	1
FT	#SUB	99	  99 	TYR	B	124	 124 	ALA	A	Protein	S	1
FT	#SUB	99	  99 	TYR	B	129	 129 	HIS	A	Protein	S	1
FT	#SUB	147	 147 	GLU	B	43	  43 	ARG	A	Protein	S	2
FT	#SUB	210	 210 	HIS	B	52	  52 	PRO	A	Protein	S	2
FT	#SUB	212	 212 	SER	B	52	  52 	PRO	A	Protein	S	1
FT	#SUB	213	 213 	PRO	B	55	  55 	MET	A	Protein	B	2
FT	#SUB	213	 213 	PRO	B	72	  72 	LYS	A	Protein	S	3
FT	#SUB	213	 213 	PRO	B	108	 108 	PHE	A	Protein	S	4
FT	#SUB	213	 213 	PRO	B	109	 109 	ASP	A	Protein	S	2
FT	#SUB	213	 213 	PRO	B	112	 112 	LEU	A	Protein	A	3
FT	#SUB	214	 214 	GLY	B	48	  48 	GLN	A	Protein	B	4
FT	#SUB	214	 214 	GLY	B	49	  49 	TRP	A	Protein	B	5
FT	#SUB	214	 214 	GLY	B	112	 112 	LEU	A	Protein	B	2
FT	#SUB	214	 214 	GLY	B	116	 116 	GLN	A	Protein	B	1
FT	#SUB	215	 215 	PHE	B	49	  49 	TRP	A	Protein	S	1
FT	#SUB	215	 215 	PHE	B	50	  50 	ASP	A	Protein	S	2
FT	#SUB	216	 216 	PHE	B	48	  48 	GLN	A	Protein	A	6
FT	#SUB	217	 217 	PRO	B	48	  48 	GLN	A	Protein	B	3
FT	#SUB	218	 218 	GLY	B	10	  10 	GLN	A	Protein	B	2
FT	#SUB	219	 219 	THR	B	10	  10 	GLN	A	Protein	S	2
FT	#SUB	231	 231 	PRO	B	79	  79 	CYS	A	Protein	S	3
FT	#SUB	251	 251 	GLU	B	52	  52 	PRO	A	Protein	S	5
FT	#SUB	292	 292 	HIS	B	50	  50 	ASP	A	Protein	A	8
FT	#SUB	292	 292 	HIS	B	51	  51 	SER	A	Protein	B	1
FT	#SUB	294	 294 	ILE	B	50	  50 	ASP	A	Protein	S	1
FT	#SUB	294	 294 	ILE	B	51	  51 	SER	A	Protein	S	2
FT	#SUB	300	 300 	PHE	B	239	 239 	ARG	D	Protein	S	2
FT	#SUB	312	 312 	SER	B	234	 234 	LEU	D	Protein	S	1
FT	#SUB	312	 312 	SER	B	236	 236 	GLY	D	Protein	S	2
FT	#SUB	312	 312 	SER	B	237	 237 	ALA	D	Protein	B	3
FT	#SUB	312	 312 	SER	B	238	 238 	GLY	D	Protein	B	2
FT	#SUB	312	 312 	SER	B	241	 241 	ARG	D	Protein	A	7
FT	#SUB	313	 313 	GLU	B	241	 241 	ARG	D	Protein	A	6
FT	#SUB	314	 314 	CYS	B	238	 238 	GLY	D	Protein	S	2
FT	#SUB	314	 314 	CYS	B	239	 239 	ARG	D	Protein	S	2
FT	#SUB	389	 389 	ILE	B	239	 239 	ARG	D	Protein	B	1
FT	#SUB	391	 391 	TYR	B	239	 239 	ARG	D	Protein	B	6
FT	#SUB	392	 392 	PHE	B	201	 201 	PRO	D	Protein	S	3
FT	#SUB	392	 392 	PHE	B	202	 202 	ARG	D	Protein	S	1
FT	#SUB	392	 392 	PHE	B	239	 239 	ARG	D	Protein	S	4
FT	#SUB	393	 393 	PRO	B	199	 199 	TYR	D	Protein	B	3
FT	#SUB	394	 394 	HIS	B	199	 199 	TYR	D	Protein	A	6
FT	#HET	7	   7 	TYR	B	12	801 	DMF	B	S	14
FT	#HET	12	  12 	ARG	B	12	801 	DMF	B	S	1
FT	#HET	18	  18 	SER	B	11	800 	DMF	B	S	4
FT	#HET	19	  19 	PRO	B	11	800 	DMF	B	A	3
FT	#HET	20	  20 	LYS	B	11	800 	DMF	B	A	6
FT	#HET	21	  21 	PHE	B	11	800 	DMF	B	S	2
FT	#HET	29	  29 	MET	B	12	801 	DMF	B	B	2
FT	#HET	30	  30 	ASP	B	12	801 	DMF	B	S	1
FT	#HET	33	  33 	ASN	B	12	801 	DMF	B	S	3
FT	#HET	38	  38 	ILE	B	12	801 	DMF	B	S	5
FT	#HET	43	  43 	ARG	B	12	801 	DMF	B	S	1
FT	#HET	43	  43 	ARG	B	13	802 	DMF	B	S	16
FT	#HET	58	  58 	ALA	B	14	901 	GOL	B	A	11
FT	#HET	61	  61 	ALA	B	14	901 	GOL	B	S	3
FT	#HET	99	  99 	TYR	B	10	700 	9Z8	B	A	9
FT	#HET	100	 100 	ASP	B	10	700 	9Z8	B	A	11
FT	#HET	100	 100 	ASP	B	11	800 	DMF	B	B	1
FT	#HET	104	 104 	PHE	B	11	800 	DMF	B	S	2
FT	#HET	110	 110 	TYR	B	11	800 	DMF	B	S	3
FT	#HET	119	 119 	LEU	B	14	901 	GOL	B	S	4
FT	#HET	141	 141 	HIS	B	10	700 	9Z8	B	S	1
FT	#HET	142	 142 	HIS	B	10	700 	9Z8	B	S	6
FT	#HET	150	 150 	GLY	B	10	700 	9Z8	B	B	4
FT	#HET	151	 151 	PHE	B	10	700 	9Z8	B	S	7
FT	#HET	151	 151 	PHE	B	11	800 	DMF	B	A	6
FT	#HET	153	 153 	TYR	B	11	800 	DMF	B	S	7
FT	#HET	159	 159 	LEU	B	14	901 	GOL	B	A	5
FT	#HET	162	 162 	HIS	B	14	901 	GOL	B	S	3
FT	#HET	163	 163 	ARG	B	14	901 	GOL	B	A	6
FT	#HET	184	 184 	ASP	B	9	601 	K	B	A	5
FT	#HET	185	 185 	LEU	B	9	601 	K	B	B	1
FT	#HET	186	 186 	ASP	B	7	500 	ZN	B	S	3
FT	#HET	186	 186 	ASP	B	9	601 	K	B	B	4
FT	#HET	186	 186 	ASP	B	10	700 	9Z8	B	S	3
FT	#HET	188	 188 	HIS	B	7	500 	ZN	B	A	5
FT	#HET	188	 188 	HIS	B	9	601 	K	B	B	2
FT	#HET	188	 188 	HIS	B	10	700 	9Z8	B	S	11
FT	#HET	189	 189 	HIS	B	15	902 	GOL	B	S	2
FT	#HET	194	 194 	GLU	B	15	902 	GOL	B	S	4
FT	#HET	197	 197 	PHE	B	8	600 	K	B	A	3
FT	#HET	200	 200 	SER	B	8	600 	K	B	B	2
FT	#HET	203	 203 	VAL	B	8	600 	K	B	B	2
FT	#HET	207	 207 	SER	B	9	601 	K	B	S	1
FT	#HET	208	 208 	VAL	B	9	601 	K	B	B	3
FT	#HET	209	 209 	HIS	B	9	601 	K	B	S	1
FT	#HET	216	 216 	PHE	B	10	700 	9Z8	B	S	9
FT	#HET	219	 219 	THR	B	15	902 	GOL	B	A	2
FT	#HET	220	 220 	GLY	B	15	902 	GOL	B	B	5
FT	#HET	221	 221 	THR	B	15	902 	GOL	B	B	6
FT	#HET	223	 223 	ASN	B	15	902 	GOL	B	S	1
FT	#HET	232	 232 	ILE	B	15	902 	GOL	B	B	1
FT	#HET	233	 233 	PHE	B	15	902 	GOL	B	A	3
FT	#HET	234	 234 	LEU	B	15	902 	GOL	B	A	9
FT	#HET	243	 243 	SER	B	8	600 	K	B	A	3
FT	#HET	246	 246 	ASN	B	15	902 	GOL	B	S	1
FT	#HET	285	 285 	ASP	B	7	500 	ZN	B	S	3
FT	#HET	285	 285 	ASP	B	10	700 	9Z8	B	S	1
FT	#HET	339	 339 	GLY	B	10	700 	9Z8	B	B	2
FT	#HET	341	 341 	TYR	B	10	700 	9Z8	B	S	6
FT	DISORDER	1	1
FT	DISORDER	81	83
FT	DISORDER	168	176
FT	DISORDER	224	228
FT	DISORDER	303	310
FT	DISORDER	395	401
CC	SEQUENCE	413 AA (ATOM);
CC	SVGIVYGDQY RQLCCSSPKF GDRYALVMDL INAYKLIPEL SRVPPLQWDS PSRMYEAVTA
CC	FHSTEYVDAL KKLQMLHCEL TADDELLMDS FSLNYDCPGF PSVFDYSLAA VQGSLAAASA
CC	LICRHCEVVI NWGGGWHHAK RSEASGFCYL NDIVLAIHRL VSSQTRVLYV DLDLHHGDGV
CC	EEAFWYSPRV VTFSVHHASP GFFPGTGTWN KLPIFLNGAG RGRFSAFNLP LEEGINDLDW
CC	SNAIGPILDS LNIVIQPSYV VVQCGADCLA TDPHRIFRLT NFYPDSECSL SGYLYAIKKI
CC	LSWKVPTLIL GGGGYNFPDT ARLWTRVTAL TIEEVKGKKM TISPEIPEHS YFSRYGPDFE
CC	LDIDYFPHDS IQKHHRRILE QLRNYADLNK LIYDYDQVYQ LYNLTGMGSL VPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	ATOM   -SVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	        *************************************************
CC	SEQRES SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	ATOM   SPSRMYEAVTAFHSTEYVDALKKLQMLHCE---LTADDELLMDSFSLNYD
CC	       ******************************   *****************
CC	SEQRES CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	ATOM   CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	       **************************************************
CC	SEQRES FCYLNDIVLAIHRLVSSTPPETSPNRQTRVLYVDLDLHHGDGVEEAFWYS
CC	ATOM   FCYLNDIVLAIHRLVSS---------QTRVLYVDLDLHHGDGVEEAFWYS
CC	       *****************         ************************
CC	SEQRES PRVVTFSVHHASPGFFPGTGTWNMVDNDKLPIFLNGAGRGRFSAFNLPLE
CC	ATOM   PRVVTFSVHHASPGFFPGTGTWN-----KLPIFLNGAGRGRFSAFNLPLE
CC	       ***********************     **********************
CC	SEQRES EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	ATOM   EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	       **************************************************
CC	SEQRES YPNLNLDSDCDSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	ATOM   YP--------DSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	       **        ****************************************
CC	SEQRES TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPHESHNKT
CC	ATOM   TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPH------
CC	       ********************************************      
CC	SEQRES LDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	ATOM   -DSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	        *********************************************
SQ	SEQUENCE	446 AA;      MW;         CN;
	MSVGIVYGDQ YRQLCCSSPK FGDRYALVMD LINAYKLIPE LSRVPPLQWD SPSRMYEAVT
	AFHSTEYVDA LKKLQMLHCE EKELTADDEL LMDSFSLNYD CPGFPSVFDY SLAAVQGSLA
	AASALICRHC EVVINWGGGW HHAKRSEASG FCYLNDIVLA IHRLVSSTPP ETSPNRQTRV
	LYVDLDLHHG DGVEEAFWYS PRVVTFSVHH ASPGFFPGTG TWNMVDNDKL PIFLNGAGRG
	RFSAFNLPLE EGINDLDWSN AIGPILDSLN IVIQPSYVVV QCGADCLATD PHRIFRLTNF
	YPNLNLDSDC DSECSLSGYL YAIKKILSWK VPTLILGGGG YNFPDTARLW TRVTALTIEE
	VKGKKMTISP EIPEHSYFSR YGPDFELDID YFPHESHNKT LDSIQKHHRR ILEQLRNYAD
	LNKLIYDYDQ VYQLYNLTGM GSLVPR
//
ID	4CQFC	STANDARD;	PRT;	446	AA.
DT	CONVERTED FROM PDB (SEQRES) 4CQF
DE	HISTONE DEACETYLASE 8
OS	SCHISTOSOMA MANSONI
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.192
FT	#SUB	300	 300 	PHE	C	239	 239 	ARG	A	Protein	S	3
FT	#SUB	312	 312 	SER	C	236	 236 	GLY	A	Protein	S	1
FT	#SUB	312	 312 	SER	C	237	 237 	ALA	A	Protein	B	3
FT	#SUB	312	 312 	SER	C	238	 238 	GLY	A	Protein	B	1
FT	#SUB	312	 312 	SER	C	241	 241 	ARG	A	Protein	B	2
FT	#SUB	313	 313 	GLU	C	241	 241 	ARG	A	Protein	A	2
FT	#SUB	314	 314 	CYS	C	238	 238 	GLY	A	Protein	S	3
FT	#SUB	314	 314 	CYS	C	239	 239 	ARG	A	Protein	S	2
FT	#SUB	389	 389 	ILE	C	239	 239 	ARG	A	Protein	B	1
FT	#SUB	391	 391 	TYR	C	239	 239 	ARG	A	Protein	B	6
FT	#SUB	392	 392 	PHE	C	201	 201 	PRO	A	Protein	S	3
FT	#SUB	392	 392 	PHE	C	202	 202 	ARG	A	Protein	S	1
FT	#SUB	392	 392 	PHE	C	239	 239 	ARG	A	Protein	S	3
FT	#SUB	393	 393 	PRO	C	199	 199 	TYR	A	Protein	B	3
FT	#SUB	394	 394 	HIS	C	199	 199 	TYR	A	Protein	A	7
FT	#SUB	89	  89 	GLU	C	129	 129 	HIS	D	Protein	S	2
FT	#SUB	90	  90 	LEU	C	40	  40 	GLU	D	Protein	S	2
FT	#SUB	90	  90 	LEU	C	41	  41 	LEU	D	Protein	S	2
FT	#SUB	90	  90 	LEU	C	42	  42 	SER	D	Protein	S	1
FT	#SUB	90	  90 	LEU	C	362	 362 	LYS	D	Protein	S	1
FT	#SUB	93	  93 	ASP	C	42	  42 	SER	D	Protein	S	4
FT	#SUB	93	  93 	ASP	C	129	 129 	HIS	D	Protein	S	6
FT	#SUB	99	  99 	TYR	C	45	  45 	PRO	D	Protein	S	2
FT	#SUB	99	  99 	TYR	C	124	 124 	ALA	D	Protein	S	1
FT	#SUB	99	  99 	TYR	C	129	 129 	HIS	D	Protein	S	2
FT	#SUB	210	 210 	HIS	C	52	  52 	PRO	D	Protein	S	2
FT	#SUB	212	 212 	SER	C	52	  52 	PRO	D	Protein	S	1
FT	#SUB	213	 213 	PRO	C	55	  55 	MET	D	Protein	B	2
FT	#SUB	213	 213 	PRO	C	72	  72 	LYS	D	Protein	S	4
FT	#SUB	213	 213 	PRO	C	108	 108 	PHE	D	Protein	S	4
FT	#SUB	213	 213 	PRO	C	109	 109 	ASP	D	Protein	S	2
FT	#SUB	213	 213 	PRO	C	112	 112 	LEU	D	Protein	A	3
FT	#SUB	214	 214 	GLY	C	48	  48 	GLN	D	Protein	B	4
FT	#SUB	214	 214 	GLY	C	49	  49 	TRP	D	Protein	B	4
FT	#SUB	214	 214 	GLY	C	112	 112 	LEU	D	Protein	B	1
FT	#SUB	214	 214 	GLY	C	116	 116 	GLN	D	Protein	B	1
FT	#SUB	215	 215 	PHE	C	49	  49 	TRP	D	Protein	A	2
FT	#SUB	215	 215 	PHE	C	50	  50 	ASP	D	Protein	S	3
FT	#SUB	216	 216 	PHE	C	48	  48 	GLN	D	Protein	A	4
FT	#SUB	217	 217 	PRO	C	48	  48 	GLN	D	Protein	B	2
FT	#SUB	218	 218 	GLY	C	10	  10 	GLN	D	Protein	B	4
FT	#SUB	219	 219 	THR	C	10	  10 	GLN	D	Protein	S	1
FT	#SUB	224	 224 	MET	C	105	 105 	PRO	D	Protein	S	1
FT	#SUB	224	 224 	MET	C	106	 106 	SER	D	Protein	S	2
FT	#SUB	224	 224 	MET	C	109	 109 	ASP	D	Protein	S	1
FT	#SUB	230	 230 	LEU	C	79	  79 	CYS	D	Protein	S	1
FT	#SUB	230	 230 	LEU	C	80	  80 	GLU	D	Protein	S	2
FT	#SUB	230	 230 	LEU	C	81	  81 	GLU	D	Protein	S	2
FT	#SUB	231	 231 	PRO	C	79	  79 	CYS	D	Protein	S	3
FT	#SUB	251	 251 	GLU	C	52	  52 	PRO	D	Protein	S	5
FT	#SUB	292	 292 	HIS	C	50	  50 	ASP	D	Protein	S	7
FT	#SUB	292	 292 	HIS	C	51	  51 	SER	D	Protein	B	1
FT	#SUB	294	 294 	ILE	C	50	  50 	ASP	D	Protein	S	1
FT	#SUB	294	 294 	ILE	C	51	  51 	SER	D	Protein	S	3
FT	#HET	7	   7 	TYR	C	21	801 	DMF	C	S	14
FT	#HET	12	  12 	ARG	C	21	801 	DMF	C	S	1
FT	#HET	15	  15 	CYS	C	24	900 	GOL	C	B	5
FT	#HET	16	  16 	CYS	C	24	900 	GOL	C	B	1
FT	#HET	18	  18 	SER	C	20	800 	DMF	C	A	5
FT	#HET	19	  19 	PRO	C	20	800 	DMF	C	A	3
FT	#HET	20	  20 	LYS	C	20	800 	DMF	C	A	6
FT	#HET	21	  21 	PHE	C	20	800 	DMF	C	S	1
FT	#HET	21	  21 	PHE	C	24	900 	GOL	C	A	8
FT	#HET	22	  22 	GLY	C	24	900 	GOL	C	B	2
FT	#HET	24	  24 	ARG	C	24	900 	GOL	C	A	12
FT	#HET	25	  25 	TYR	C	24	900 	GOL	C	A	11
FT	#HET	29	  29 	MET	C	21	801 	DMF	C	A	3
FT	#HET	30	  30 	ASP	C	21	801 	DMF	C	S	1
FT	#HET	33	  33 	ASN	C	21	801 	DMF	C	S	5
FT	#HET	38	  38 	ILE	C	21	801 	DMF	C	S	2
FT	#HET	43	  43 	ARG	C	22	802 	DMF	C	S	7
FT	#HET	99	  99 	TYR	C	19	700 	9Z8	C	A	9
FT	#HET	100	 100 	ASP	C	19	700 	9Z8	C	A	17
FT	#HET	100	 100 	ASP	C	20	800 	DMF	C	B	1
FT	#HET	104	 104 	PHE	C	20	800 	DMF	C	S	4
FT	#HET	110	 110 	TYR	C	20	800 	DMF	C	S	3
FT	#HET	110	 110 	TYR	C	24	900 	GOL	C	S	3
FT	#HET	131	 131 	GLU	C	23	803 	DMF	C	A	6
FT	#HET	132	 132 	VAL	C	23	803 	DMF	C	S	1
FT	#HET	136	 136 	TRP	C	24	900 	GOL	C	B	1
FT	#HET	140	 140 	TRP	C	24	900 	GOL	C	S	4
FT	#HET	141	 141 	HIS	C	19	700 	9Z8	C	S	1
FT	#HET	142	 142 	HIS	C	19	700 	9Z8	C	S	5
FT	#HET	150	 150 	GLY	C	19	700 	9Z8	C	B	4
FT	#HET	151	 151 	PHE	C	19	700 	9Z8	C	S	10
FT	#HET	151	 151 	PHE	C	20	800 	DMF	C	A	6
FT	#HET	153	 153 	TYR	C	20	800 	DMF	C	S	6
FT	#HET	184	 184 	ASP	C	17	600 	K	C	A	5
FT	#HET	186	 186 	ASP	C	16	500 	ZN	C	S	3
FT	#HET	186	 186 	ASP	C	17	600 	K	C	A	5
FT	#HET	186	 186 	ASP	C	19	700 	9Z8	C	S	3
FT	#HET	188	 188 	HIS	C	16	500 	ZN	C	A	5
FT	#HET	188	 188 	HIS	C	17	600 	K	C	B	2
FT	#HET	188	 188 	HIS	C	19	700 	9Z8	C	S	10
FT	#HET	189	 189 	HIS	C	25	901 	GOL	C	S	2
FT	#HET	194	 194 	GLU	C	25	901 	GOL	C	S	4
FT	#HET	197	 197 	PHE	C	18	601 	K	C	A	3
FT	#HET	200	 200 	SER	C	18	601 	K	C	B	2
FT	#HET	203	 203 	VAL	C	18	601 	K	C	B	2
FT	#HET	207	 207 	SER	C	17	600 	K	C	S	1
FT	#HET	208	 208 	VAL	C	17	600 	K	C	B	3
FT	#HET	209	 209 	HIS	C	17	600 	K	C	S	1
FT	#HET	216	 216 	PHE	C	19	700 	9Z8	C	S	7
FT	#HET	219	 219 	THR	C	25	901 	GOL	C	A	3
FT	#HET	220	 220 	GLY	C	25	901 	GOL	C	B	5
FT	#HET	221	 221 	THR	C	25	901 	GOL	C	B	6
FT	#HET	233	 233 	PHE	C	25	901 	GOL	C	A	3
FT	#HET	234	 234 	LEU	C	25	901 	GOL	C	A	8
FT	#HET	243	 243 	SER	C	18	601 	K	C	A	4
FT	#HET	246	 246 	ASN	C	25	901 	GOL	C	S	1
FT	#HET	285	 285 	ASP	C	16	500 	ZN	C	S	3
FT	#HET	285	 285 	ASP	C	19	700 	9Z8	C	S	2
FT	#HET	291	 291 	PRO	C	34	901 	GOL	D	B	6
FT	#HET	292	 292 	HIS	C	34	901 	GOL	D	B	6
FT	#HET	301	 301 	TYR	C	26	902 	GOL	C	S	9
FT	#HET	330	 330 	LYS	C	23	803 	DMF	C	A	9
FT	#HET	331	 331 	VAL	C	23	803 	DMF	C	B	3
FT	#HET	339	 339 	GLY	C	19	700 	9Z8	C	B	2
FT	#HET	341	 341 	TYR	C	19	700 	9Z8	C	S	6
FT	#HET	352	 352 	ARG	C	26	902 	GOL	C	S	3
FT	#HET	355	 355 	ALA	C	26	902 	GOL	C	S	1
FT	#HET	361	 361 	VAL	C	23	803 	DMF	C	A	2
FT	#HET	366	 366 	MET	C	26	902 	GOL	C	B	5
FT	#HET	367	 367 	THR	C	26	902 	GOL	C	B	3
FT	#HET	368	 368 	ILE	C	26	902 	GOL	C	A	9
FT	DISORDER	1	1
FT	DISORDER	81	83
FT	DISORDER	169	176
FT	DISORDER	225	228
FT	DISORDER	304	311
FT	DISORDER	395	399
CC	SEQUENCE	417 AA (ATOM);
CC	SVGIVYGDQY RQLCCSSPKF GDRYALVMDL INAYKLIPEL SRVPPLQWDS PSRMYEAVTA
CC	FHSTEYVDAL KKLQMLHCEL TADDELLMDS FSLNYDCPGF PSVFDYSLAA VQGSLAAASA
CC	LICRHCEVVI NWGGGWHHAK RSEASGFCYL NDIVLAIHRL VSSTQTRVLY VDLDLHHGDG
CC	VEEAFWYSPR VVTFSVHHAS PGFFPGTGTW NMKLPIFLNG AGRGRFSAFN LPLEEGINDL
CC	DWSNAIGPIL DSLNIVIQPS YVVVQCGADC LATDPHRIFR LTNFYPNSEC SLSGYLYAIK
CC	KILSWKVPTL ILGGGGYNFP DTARLWTRVT ALTIEEVKGK KMTISPEIPE HSYFSRYGPD
CC	FELDIDYFPH TLDSIQKHHR RILEQLRNYA DLNKLIYDYD QVYQLYNLTG MGSLVPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	ATOM   -SVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	        *************************************************
CC	SEQRES SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	ATOM   SPSRMYEAVTAFHSTEYVDALKKLQMLHCE---LTADDELLMDSFSLNYD
CC	       ******************************   *****************
CC	SEQRES CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	ATOM   CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	       **************************************************
CC	SEQRES FCYLNDIVLAIHRLVSSTPPETSPNRQTRVLYVDLDLHHGDGVEEAFWYS
CC	ATOM   FCYLNDIVLAIHRLVSST--------QTRVLYVDLDLHHGDGVEEAFWYS
CC	       ******************        ************************
CC	SEQRES PRVVTFSVHHASPGFFPGTGTWNMVDNDKLPIFLNGAGRGRFSAFNLPLE
CC	ATOM   PRVVTFSVHHASPGFFPGTGTWNM----KLPIFLNGAGRGRFSAFNLPLE
CC	       ************************    **********************
CC	SEQRES EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	ATOM   EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	       **************************************************
CC	SEQRES YPNLNLDSDCDSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	ATOM   YPN--------SECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	       ***        ***************************************
CC	SEQRES TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPHESHNKT
CC	ATOM   TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPH-----T
CC	       ********************************************     *
CC	SEQRES LDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	ATOM   LDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	       **********************************************
SQ	SEQUENCE	446 AA;      MW;         CN;
	MSVGIVYGDQ YRQLCCSSPK FGDRYALVMD LINAYKLIPE LSRVPPLQWD SPSRMYEAVT
	AFHSTEYVDA LKKLQMLHCE EKELTADDEL LMDSFSLNYD CPGFPSVFDY SLAAVQGSLA
	AASALICRHC EVVINWGGGW HHAKRSEASG FCYLNDIVLA IHRLVSSTPP ETSPNRQTRV
	LYVDLDLHHG DGVEEAFWYS PRVVTFSVHH ASPGFFPGTG TWNMVDNDKL PIFLNGAGRG
	RFSAFNLPLE EGINDLDWSN AIGPILDSLN IVIQPSYVVV QCGADCLATD PHRIFRLTNF
	YPNLNLDSDC DSECSLSGYL YAIKKILSWK VPTLILGGGG YNFPDTARLW TRVTALTIEE
	VKGKKMTISP EIPEHSYFSR YGPDFELDID YFPHESHNKT LDSIQKHHRR ILEQLRNYAD
	LNKLIYDYDQ VYQLYNLTGM GSLVPR
//
ID	4CQFD	STANDARD;	PRT;	446	AA.
DT	CONVERTED FROM PDB (SEQRES) 4CQF
DE	HISTONE DEACETYLASE 8
OS	SCHISTOSOMA MANSONI
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.192
FT	#SUB	199	 199 	TYR	D	393	 393 	PRO	B	Protein	S	3
FT	#SUB	199	 199 	TYR	D	394	 394 	HIS	B	Protein	S	6
FT	#SUB	201	 201 	PRO	D	392	 392 	PHE	B	Protein	S	3
FT	#SUB	202	 202 	ARG	D	392	 392 	PHE	B	Protein	S	1
FT	#SUB	234	 234 	LEU	D	312	 312 	SER	B	Protein	S	1
FT	#SUB	236	 236 	GLY	D	312	 312 	SER	B	Protein	B	2
FT	#SUB	237	 237 	ALA	D	312	 312 	SER	B	Protein	A	3
FT	#SUB	238	 238 	GLY	D	312	 312 	SER	B	Protein	B	2
FT	#SUB	238	 238 	GLY	D	314	 314 	CYS	B	Protein	B	2
FT	#SUB	239	 239 	ARG	D	300	 300 	PHE	B	Protein	S	2
FT	#SUB	239	 239 	ARG	D	314	 314 	CYS	B	Protein	A	2
FT	#SUB	239	 239 	ARG	D	389	 389 	ILE	B	Protein	S	1
FT	#SUB	239	 239 	ARG	D	391	 391 	TYR	B	Protein	S	6
FT	#SUB	239	 239 	ARG	D	392	 392 	PHE	B	Protein	S	4
FT	#SUB	241	 241 	ARG	D	312	 312 	SER	B	Protein	S	7
FT	#SUB	241	 241 	ARG	D	313	 313 	GLU	B	Protein	S	6
FT	#SUB	10	  10 	GLN	D	218	 218 	GLY	C	Protein	S	4
FT	#SUB	10	  10 	GLN	D	219	 219 	THR	C	Protein	S	1
FT	#SUB	40	  40 	GLU	D	90	  90 	LEU	C	Protein	B	2
FT	#SUB	41	  41 	LEU	D	90	  90 	LEU	C	Protein	B	2
FT	#SUB	42	  42 	SER	D	90	  90 	LEU	C	Protein	B	1
FT	#SUB	42	  42 	SER	D	93	  93 	ASP	C	Protein	S	4
FT	#SUB	45	  45 	PRO	D	99	  99 	TYR	C	Protein	S	2
FT	#SUB	48	  48 	GLN	D	214	 214 	GLY	C	Protein	A	4
FT	#SUB	48	  48 	GLN	D	216	 216 	PHE	C	Protein	S	4
FT	#SUB	48	  48 	GLN	D	217	 217 	PRO	C	Protein	S	2
FT	#SUB	49	  49 	TRP	D	214	 214 	GLY	C	Protein	A	4
FT	#SUB	49	  49 	TRP	D	215	 215 	PHE	C	Protein	B	2
FT	#SUB	50	  50 	ASP	D	215	 215 	PHE	C	Protein	B	3
FT	#SUB	50	  50 	ASP	D	292	 292 	HIS	C	Protein	A	7
FT	#SUB	50	  50 	ASP	D	294	 294 	ILE	C	Protein	B	1
FT	#SUB	51	  51 	SER	D	292	 292 	HIS	C	Protein	S	1
FT	#SUB	51	  51 	SER	D	294	 294 	ILE	C	Protein	A	3
FT	#SUB	52	  52 	PRO	D	210	 210 	HIS	C	Protein	S	2
FT	#SUB	52	  52 	PRO	D	212	 212 	SER	C	Protein	S	1
FT	#SUB	52	  52 	PRO	D	251	 251 	GLU	C	Protein	S	5
FT	#SUB	55	  55 	MET	D	213	 213 	PRO	C	Protein	S	2
FT	#SUB	72	  72 	LYS	D	213	 213 	PRO	C	Protein	S	4
FT	#SUB	79	  79 	CYS	D	230	 230 	LEU	C	Protein	B	1
FT	#SUB	79	  79 	CYS	D	231	 231 	PRO	C	Protein	A	3
FT	#SUB	80	  80 	GLU	D	230	 230 	LEU	C	Protein	B	2
FT	#SUB	81	  81 	GLU	D	230	 230 	LEU	C	Protein	A	2
FT	#SUB	105	 105 	PRO	D	224	 224 	MET	C	Protein	B	1
FT	#SUB	106	 106 	SER	D	224	 224 	MET	C	Protein	S	2
FT	#SUB	108	 108 	PHE	D	213	 213 	PRO	C	Protein	S	4
FT	#SUB	109	 109 	ASP	D	213	 213 	PRO	C	Protein	S	2
FT	#SUB	109	 109 	ASP	D	224	 224 	MET	C	Protein	S	1
FT	#SUB	112	 112 	LEU	D	213	 213 	PRO	C	Protein	S	3
FT	#SUB	112	 112 	LEU	D	214	 214 	GLY	C	Protein	S	1
FT	#SUB	116	 116 	GLN	D	214	 214 	GLY	C	Protein	S	1
FT	#SUB	124	 124 	ALA	D	99	  99 	TYR	C	Protein	S	1
FT	#SUB	129	 129 	HIS	D	89	  89 	GLU	C	Protein	S	2
FT	#SUB	129	 129 	HIS	D	93	  93 	ASP	C	Protein	S	6
FT	#SUB	129	 129 	HIS	D	99	  99 	TYR	C	Protein	S	2
FT	#SUB	362	 362 	LYS	D	90	  90 	LEU	C	Protein	S	1
FT	#HET	18	  18 	SER	D	31	800 	DMF	D	A	6
FT	#HET	19	  19 	PRO	D	31	800 	DMF	D	A	3
FT	#HET	20	  20 	LYS	D	31	800 	DMF	D	A	7
FT	#HET	21	  21 	PHE	D	31	800 	DMF	D	S	2
FT	#HET	50	  50 	ASP	D	34	901 	GOL	D	S	3
FT	#HET	51	  51 	SER	D	34	901 	GOL	D	S	5
FT	#HET	54	  54 	ARG	D	34	901 	GOL	D	S	7
FT	#HET	99	  99 	TYR	D	30	700 	9Z8	D	A	5
FT	#HET	100	 100 	ASP	D	30	700 	9Z8	D	A	14
FT	#HET	100	 100 	ASP	D	31	800 	DMF	D	B	1
FT	#HET	104	 104 	PHE	D	31	800 	DMF	D	S	2
FT	#HET	110	 110 	TYR	D	31	800 	DMF	D	S	3
FT	#HET	131	 131 	GLU	D	32	801 	DMF	D	A	7
FT	#HET	132	 132 	VAL	D	32	801 	DMF	D	S	1
FT	#HET	141	 141 	HIS	D	30	700 	9Z8	D	S	1
FT	#HET	142	 142 	HIS	D	30	700 	9Z8	D	S	6
FT	#HET	150	 150 	GLY	D	30	700 	9Z8	D	B	3
FT	#HET	151	 151 	PHE	D	30	700 	9Z8	D	S	7
FT	#HET	151	 151 	PHE	D	31	800 	DMF	D	A	6
FT	#HET	153	 153 	TYR	D	31	800 	DMF	D	S	6
FT	#HET	184	 184 	ASP	D	29	601 	K	D	A	5
FT	#HET	186	 186 	ASP	D	27	500 	ZN	D	S	3
FT	#HET	186	 186 	ASP	D	29	601 	K	D	A	5
FT	#HET	186	 186 	ASP	D	30	700 	9Z8	D	S	3
FT	#HET	188	 188 	HIS	D	27	500 	ZN	D	A	5
FT	#HET	188	 188 	HIS	D	29	601 	K	D	B	2
FT	#HET	188	 188 	HIS	D	30	700 	9Z8	D	S	14
FT	#HET	189	 189 	HIS	D	33	900 	GOL	D	S	2
FT	#HET	194	 194 	GLU	D	33	900 	GOL	D	S	4
FT	#HET	197	 197 	PHE	D	28	600 	K	D	B	2
FT	#HET	200	 200 	SER	D	28	600 	K	D	B	2
FT	#HET	203	 203 	VAL	D	28	600 	K	D	B	2
FT	#HET	207	 207 	SER	D	29	601 	K	D	S	1
FT	#HET	208	 208 	VAL	D	29	601 	K	D	B	3
FT	#HET	209	 209 	HIS	D	29	601 	K	D	S	1
FT	#HET	216	 216 	PHE	D	30	700 	9Z8	D	S	8
FT	#HET	219	 219 	THR	D	33	900 	GOL	D	A	5
FT	#HET	220	 220 	GLY	D	33	900 	GOL	D	B	5
FT	#HET	221	 221 	THR	D	33	900 	GOL	D	B	6
FT	#HET	223	 223 	ASN	D	33	900 	GOL	D	S	4
FT	#HET	232	 232 	ILE	D	33	900 	GOL	D	B	1
FT	#HET	233	 233 	PHE	D	33	900 	GOL	D	A	4
FT	#HET	234	 234 	LEU	D	33	900 	GOL	D	A	8
FT	#HET	243	 243 	SER	D	28	600 	K	D	A	4
FT	#HET	246	 246 	ASN	D	33	900 	GOL	D	S	1
FT	#HET	285	 285 	ASP	D	27	500 	ZN	D	S	3
FT	#HET	285	 285 	ASP	D	30	700 	9Z8	D	S	1
FT	#HET	327	 327 	LEU	D	32	801 	DMF	D	B	1
FT	#HET	330	 330 	LYS	D	32	801 	DMF	D	A	5
FT	#HET	331	 331 	VAL	D	32	801 	DMF	D	B	6
FT	#HET	339	 339 	GLY	D	30	700 	9Z8	D	B	2
FT	#HET	341	 341 	TYR	D	30	700 	9Z8	D	S	6
FT	#HET	361	 361 	VAL	D	32	801 	DMF	D	S	1
FT	DISORDER	1	1
FT	DISORDER	169	176
FT	DISORDER	224	230
FT	DISORDER	304	314
FT	DISORDER	394	401
FT	DISORDER	436	446
CC	SEQUENCE	400 AA (ATOM);
CC	SVGIVYGDQY RQLCCSSPKF GDRYALVMDL INAYKLIPEL SRVPPLQWDS PSRMYEAVTA
CC	FHSTEYVDAL KKLQMLHCEE KELTADDELL MDSFSLNYDC PGFPSVFDYS LAAVQGSLAA
CC	ASALICRHCE VVINWGGGWH HAKRSEASGF CYLNDIVLAI HRLVSSTQTR VLYVDLDLHH
CC	GDGVEEAFWY SPRVVTFSVH HASPGFFPGT GTWNPIFLNG AGRGRFSAFN LPLEEGINDL
CC	DWSNAIGPIL DSLNIVIQPS YVVVQCGADC LATDPHRIFR LTNFYPNSLS GYLYAIKKIL
CC	SWKVPTLILG GGGYNFPDTA RLWTRVTALT IEEVKGKKMT ISPEIPEHSY FSRYGPDFEL
CC	DIDYFPDSIQ KHHRRILEQL RNYADLNKLI YDYDQVYQLY
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MSVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	ATOM   -SVGIVYGDQYRQLCCSSPKFGDRYALVMDLINAYKLIPELSRVPPLQWD
CC	        *************************************************
CC	SEQRES SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	ATOM   SPSRMYEAVTAFHSTEYVDALKKLQMLHCEEKELTADDELLMDSFSLNYD
CC	       **************************************************
CC	SEQRES CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	ATOM   CPGFPSVFDYSLAAVQGSLAAASALICRHCEVVINWGGGWHHAKRSEASG
CC	       **************************************************
CC	SEQRES FCYLNDIVLAIHRLVSSTPPETSPNRQTRVLYVDLDLHHGDGVEEAFWYS
CC	ATOM   FCYLNDIVLAIHRLVSST--------QTRVLYVDLDLHHGDGVEEAFWYS
CC	       ******************        ************************
CC	SEQRES PRVVTFSVHHASPGFFPGTGTWNMVDNDKLPIFLNGAGRGRFSAFNLPLE
CC	ATOM   PRVVTFSVHHASPGFFPGTGTWN-------PIFLNGAGRGRFSAFNLPLE
CC	       ***********************       ********************
CC	SEQRES EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	ATOM   EGINDLDWSNAIGPILDSLNIVIQPSYVVVQCGADCLATDPHRIFRLTNF
CC	       **************************************************
CC	SEQRES YPNLNLDSDCDSECSLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	ATOM   YPN-----------SLSGYLYAIKKILSWKVPTLILGGGGYNFPDTARLW
CC	       ***           ************************************
CC	SEQRES TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFPHESHNKT
CC	ATOM   TRVTALTIEEVKGKKMTISPEIPEHSYFSRYGPDFELDIDYFP-------
CC	       *******************************************       
CC	SEQRES LDSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLYNLTGMGSLVPR
CC	ATOM   -DSIQKHHRRILEQLRNYADLNKLIYDYDQVYQLY-----------
CC	        **********************************           
SQ	SEQUENCE	446 AA;      MW;         CN;
	MSVGIVYGDQ YRQLCCSSPK FGDRYALVMD LINAYKLIPE LSRVPPLQWD SPSRMYEAVT
	AFHSTEYVDA LKKLQMLHCE EKELTADDEL LMDSFSLNYD CPGFPSVFDY SLAAVQGSLA
	AASALICRHC EVVINWGGGW HHAKRSEASG FCYLNDIVLA IHRLVSSTPP ETSPNRQTRV
	LYVDLDLHHG DGVEEAFWYS PRVVTFSVHH ASPGFFPGTG TWNMVDNDKL PIFLNGAGRG
	RFSAFNLPLE EGINDLDWSN AIGPILDSLN IVIQPSYVVV QCGADCLATD PHRIFRLTNF
	YPNLNLDSDC DSECSLSGYL YAIKKILSWK VPTLILGGGG YNFPDTARLW TRVTALTIEE
	VKGKKMTISP EIPEHSYFSR YGPDFELDID YFPHESHNKT LDSIQKHHRR ILEQLRNYAD
	LNKLIYDYDQ VYQLYNLTGM GSLVPR
//