ID 4CHYA STANDARD; PRT; 183 AA. DT CONVERTED FROM PDB (SEQRES) 4CHY DE INTEGRASE OS HUMAN IMMUNODEFICIENCY VIRUS 1 CC EXPDTA X-RAY DIFFRACTION CC RESOLU 1.700 CC R-Factor 0.211 FT #SUB 54 83 TYR A 78 107 ARG B Protein S 7 FT #SUB 56 85 GLU A 78 107 ARG B Protein S 9 FT #SUB 57 86 ALA A 78 107 ARG B Protein B 2 FT #SUB 70 99 TYR A 144 173 LYS B Protein S 7 FT #SUB 70 99 TYR A 145 174 THR B Protein S 2 FT #SUB 70 99 TYR A 148 177 GLN B Protein S 4 FT #SUB 73 102 LEU A 145 174 THR B Protein S 1 FT #SUB 73 102 LEU A 148 177 GLN B Protein S 2 FT #SUB 73 102 LEU A 149 178 MET B Protein S 2 FT #SUB 74 103 LYS A 148 177 GLN B Protein S 3 FT #SUB 76 105 ALA A 152 181 PHE B Protein A 5 FT #SUB 76 105 ALA A 156 185 HIS B Protein B 2 FT #SUB 77 106 GLY A 152 181 PHE B Protein B 4 FT #SUB 77 106 GLY A 155 184 ASN B Protein B 3 FT #SUB 78 107 ARG A 54 83 TYR B Protein A 7 FT #SUB 78 107 ARG A 56 85 GLU B Protein S 9 FT #SUB 78 107 ARG A 57 86 ALA B Protein S 2 FT #SUB 78 107 ARG A 79 108 TRP B Protein B 1 FT #SUB 78 107 ARG A 148 177 GLN B Protein S 5 FT #SUB 78 107 ARG A 151 180 VAL B Protein S 1 FT #SUB 79 108 TRP A 78 107 ARG B Protein S 1 FT #SUB 79 108 TRP A 79 108 TRP B Protein S 8 FT #SUB 103 132 TRP A 139 168 GLN B Protein S 4 FT #SUB 103 132 TRP A 149 178 MET B Protein S 13 FT #SUB 103 132 TRP A 152 181 PHE B Protein S 2 FT #SUB 103 132 TRP A 153 182 ILE B Protein S 1 FT #SUB 104 133 ALA A 152 181 PHE B Protein A 6 FT #SUB 139 168 GLN A 103 132 TRP B Protein S 4 FT #SUB 144 173 LYS A 70 99 TYR B Protein A 7 FT #SUB 145 174 THR A 70 99 TYR B Protein A 2 FT #SUB 145 174 THR A 73 102 LEU B Protein B 1 FT #SUB 148 177 GLN A 70 99 TYR B Protein S 4 FT #SUB 148 177 GLN A 73 102 LEU B Protein S 2 FT #SUB 148 177 GLN A 74 103 LYS B Protein S 3 FT #SUB 148 177 GLN A 78 107 ARG B Protein S 5 FT #SUB 149 178 MET A 73 102 LEU B Protein A 2 FT #SUB 149 178 MET A 103 132 TRP B Protein A 13 FT #SUB 151 180 VAL A 78 107 ARG B Protein S 1 FT #SUB 152 181 PHE A 76 105 ALA B Protein S 5 FT #SUB 152 181 PHE A 77 106 GLY B Protein A 4 FT #SUB 152 181 PHE A 103 132 TRP B Protein S 2 FT #SUB 152 181 PHE A 104 133 ALA B Protein S 6 FT #SUB 153 182 ILE A 103 132 TRP B Protein S 1 FT #SUB 155 184 ASN A 77 106 GLY B Protein S 3 FT #SUB 156 185 HIS A 76 105 ALA B Protein S 2 FT #SUB 169 198 GLU A 179 208 ILE B Protein S 4 FT #SUB 172 201 VAL A 172 201 VAL B Protein A 2 FT #SUB 172 201 VAL A 175 204 ILE B Protein S 1 FT #SUB 172 201 VAL A 176 205 ALA B Protein S 3 FT #SUB 172 201 VAL A 179 208 ILE B Protein S 1 FT #SUB 173 202 ASP A 179 208 ILE B Protein S 2 FT #SUB 173 202 ASP A 180 209 GLN B Protein S 5 FT #SUB 175 204 ILE A 172 201 VAL B Protein S 1 FT #SUB 176 205 ALA A 172 201 VAL B Protein A 3 FT #SUB 176 205 ALA A 176 205 ALA B Protein S 1 FT #SUB 179 208 ILE A 169 198 GLU B Protein S 4 FT #SUB 179 208 ILE A 172 201 VAL B Protein S 1 FT #SUB 179 208 ILE A 173 202 ASP B Protein S 1 FT #SUB 180 209 GLN A 173 202 ASP B Protein S 5 FT #HET 37 66 THR A 1 1210 SO4 A A 8 FT #HET 38 67 HIS A 1 1210 SO4 A A 12 FT #HET 40 69 GLU A 3 1212 SO4 A S 1 FT #HET 42 71 LYS A 3 1212 SO4 A S 2 FT #HET 56 85 GLU A 7 1216 EDO A S 5 FT #HET 57 86 ALA A 7 1216 EDO A B 1 FT #HET 65 94 GLY A 2 1211 SO4 A B 2 FT #HET 66 95 GLN A 6 1215 ACY A A 3 FT #HET 66 95 GLN A 9 1218 C5Q A A 5 FT #HET 67 96 GLU A 6 1215 ACY A A 5 FT #HET 69 98 ALA A 9 1218 C5Q A A 4 FT #HET 70 99 TYR A 4 1213 ACY A S 6 FT #HET 70 99 TYR A 6 1215 ACY A S 5 FT #HET 70 99 TYR A 9 1218 C5Q A A 5 FT #HET 71 100 PHE A 7 1216 EDO A A 7 FT #HET 73 102 LEU A 9 1218 C5Q A S 1 FT #HET 74 103 LYS A 4 1213 ACY A S 3 FT #HET 74 103 LYS A 7 1216 EDO A A 3 FT #HET 75 104 LEU A 7 1216 EDO A A 5 FT #HET 76 105 ALA A 15 1215 C5Q B B 1 FT #HET 77 106 GLY A 15 1215 C5Q B B 1 FT #HET 78 107 ARG A 15 1215 C5Q B B 3 FT #HET 79 108 TRP A 15 1215 C5Q B B 6 FT #HET 80 109 PRO A 15 1215 C5Q B A 13 FT #HET 94 123 SER A 2 1211 SO4 A A 6 FT #HET 95 124 THR A 2 1211 SO4 A A 5 FT #HET 96 125 THR A 2 1211 SO4 A A 7 FT #HET 96 125 THR A 9 1218 C5Q A A 5 FT #HET 99 128 ALA A 9 1218 C5Q A A 4 FT #HET 100 129 ALA A 9 1218 C5Q A A 6 FT #HET 102 131 TRP A 9 1218 C5Q A S 4 FT #HET 103 132 TRP A 9 1218 C5Q A S 1 FT #HET 130 159 LYS A 1 1210 SO4 A S 4 FT #HET 137 166 ARG A 3 1212 SO4 A S 1 FT #HET 139 168 GLN A 14 1214 C5Q B B 5 FT #HET 141 170 GLU A 3 1212 SO4 A B 1 FT #HET 142 171 HIS A 3 1212 SO4 A A 10 FT #HET 143 172 LEU A 3 1212 SO4 A A 5 FT #HET 144 173 LYS A 13 1213 ACY B S 2 FT #HET 145 174 THR A 14 1214 C5Q B S 1 FT #HET 149 178 MET A 14 1214 C5Q B S 3 FT #HET 156 185 HIS A 8 1217 C5Q A A 12 FT #HET 158 187 ARG A 8 1217 C5Q A S 2 FT #HET 166 195 SER A 8 1217 C5Q A S 4 FT #HET 168 197 GLY A 8 1217 C5Q A B 9 FT #HET 169 198 GLU A 8 1217 C5Q A A 6 FT #HET 175 204 ILE A 15 1215 C5Q B S 2 FT #HET 178 207 ASP A 15 1215 C5Q B S 3 FT #HET 179 208 ILE A 15 1215 C5Q B S 1 FT DISORDER 1 27 FT DISORDER 160 164 FT DISORDER 181 183 CC SEQUENCE 148 AA (ATOM); CC SPGIWQLDCT HLEGKVILVA VHVASGYIEA EVIPAETGQE TAYFLLKLAG RWPVKTVHTD CC NGSNFTSTTV KAACWWAGIK QEDGIPYNPQ SQGVIESMNK ELKKIIGQVR DQAEHLKTAV CC QMAVFIHNHK RKYSAGERIV DIIATDIQ CC !---- CC ALIGNMENT OF SEQRES AND ATOMRES CC SEQRES MGSSHHHHHHSSGLVPRGSHMHGQVDSSPGIWQLDCTHLEGKVILVAVHV CC ATOM ---------------------------SPGIWQLDCTHLEGKVILVAVHV CC *********************** CC SEQRES ASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAA CC ATOM ASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAA CC ************************************************** CC SEQRES CWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMA CC ATOM CWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMA CC ************************************************** CC SEQRES VFIHNHKRKGGIGGYSAGERIVDIIATDIQTKE CC ATOM VFIHNHKRK-----YSAGERIVDIIATDIQ--- CC ********* **************** SQ SEQUENCE 183 AA; MW; CN; MGSSHHHHHH SSGLVPRGSH MHGQVDSSPG IWQLDCTHLE GKVILVAVHV ASGYIEAEVI PAETGQETAY FLLKLAGRWP VKTVHTDNGS NFTSTTVKAA CWWAGIKQED GIPYNPQSQG VIESMNKELK KIIGQVRDQA EHLKTAVQMA VFIHNHKRKG GIGGYSAGER IVDIIATDIQ TKE // ID 4CHYB STANDARD; PRT; 183 AA. DT CONVERTED FROM PDB (SEQRES) 4CHY DE INTEGRASE OS HUMAN IMMUNODEFICIENCY VIRUS 1 CC EXPDTA X-RAY DIFFRACTION CC RESOLU 1.700 CC R-Factor 0.211 FT #SUB 54 83 TYR B 78 107 ARG A Protein S 7 FT #SUB 56 85 GLU B 78 107 ARG A Protein S 9 FT #SUB 57 86 ALA B 78 107 ARG A Protein B 2 FT #SUB 70 99 TYR B 144 173 LYS A Protein S 7 FT #SUB 70 99 TYR B 145 174 THR A Protein S 2 FT #SUB 70 99 TYR B 148 177 GLN A Protein S 4 FT #SUB 73 102 LEU B 145 174 THR A Protein S 1 FT #SUB 73 102 LEU B 148 177 GLN A Protein S 2 FT #SUB 73 102 LEU B 149 178 MET A Protein S 2 FT #SUB 74 103 LYS B 148 177 GLN A Protein S 3 FT #SUB 76 105 ALA B 152 181 PHE A Protein A 5 FT #SUB 76 105 ALA B 156 185 HIS A Protein B 2 FT #SUB 77 106 GLY B 152 181 PHE A Protein B 4 FT #SUB 77 106 GLY B 155 184 ASN A Protein B 3 FT #SUB 78 107 ARG B 54 83 TYR A Protein A 7 FT #SUB 78 107 ARG B 56 85 GLU A Protein S 9 FT #SUB 78 107 ARG B 57 86 ALA A Protein S 2 FT #SUB 78 107 ARG B 79 108 TRP A Protein B 1 FT #SUB 78 107 ARG B 148 177 GLN A Protein S 5 FT #SUB 78 107 ARG B 151 180 VAL A Protein S 1 FT #SUB 79 108 TRP B 78 107 ARG A Protein S 1 FT #SUB 79 108 TRP B 79 108 TRP A Protein S 8 FT #SUB 103 132 TRP B 139 168 GLN A Protein S 4 FT #SUB 103 132 TRP B 149 178 MET A Protein S 13 FT #SUB 103 132 TRP B 152 181 PHE A Protein S 2 FT #SUB 103 132 TRP B 153 182 ILE A Protein S 1 FT #SUB 104 133 ALA B 152 181 PHE A Protein A 6 FT #SUB 139 168 GLN B 103 132 TRP A Protein S 4 FT #SUB 144 173 LYS B 70 99 TYR A Protein A 7 FT #SUB 145 174 THR B 70 99 TYR A Protein A 2 FT #SUB 145 174 THR B 73 102 LEU A Protein B 1 FT #SUB 148 177 GLN B 70 99 TYR A Protein S 4 FT #SUB 148 177 GLN B 73 102 LEU A Protein S 2 FT #SUB 148 177 GLN B 74 103 LYS A Protein S 3 FT #SUB 148 177 GLN B 78 107 ARG A Protein S 5 FT #SUB 149 178 MET B 73 102 LEU A Protein A 2 FT #SUB 149 178 MET B 103 132 TRP A Protein A 13 FT #SUB 151 180 VAL B 78 107 ARG A Protein S 1 FT #SUB 152 181 PHE B 76 105 ALA A Protein S 5 FT #SUB 152 181 PHE B 77 106 GLY A Protein A 4 FT #SUB 152 181 PHE B 103 132 TRP A Protein S 2 FT #SUB 152 181 PHE B 104 133 ALA A Protein S 6 FT #SUB 153 182 ILE B 103 132 TRP A Protein S 1 FT #SUB 155 184 ASN B 77 106 GLY A Protein S 3 FT #SUB 156 185 HIS B 76 105 ALA A Protein S 2 FT #SUB 169 198 GLU B 179 208 ILE A Protein S 4 FT #SUB 172 201 VAL B 172 201 VAL A Protein A 2 FT #SUB 172 201 VAL B 175 204 ILE A Protein S 1 FT #SUB 172 201 VAL B 176 205 ALA A Protein S 3 FT #SUB 172 201 VAL B 179 208 ILE A Protein S 1 FT #SUB 173 202 ASP B 179 208 ILE A Protein S 1 FT #SUB 173 202 ASP B 180 209 GLN A Protein S 5 FT #SUB 175 204 ILE B 172 201 VAL A Protein S 1 FT #SUB 176 205 ALA B 172 201 VAL A Protein A 3 FT #SUB 176 205 ALA B 176 205 ALA A Protein S 1 FT #SUB 179 208 ILE B 169 198 GLU A Protein S 4 FT #SUB 179 208 ILE B 172 201 VAL A Protein S 1 FT #SUB 179 208 ILE B 173 202 ASP A Protein S 2 FT #SUB 180 209 GLN B 173 202 ASP A Protein S 5 FT #HET 37 66 THR B 10 1210 SO4 B A 8 FT #HET 38 67 HIS B 10 1210 SO4 B A 11 FT #HET 42 71 LYS B 11 1211 SO4 B S 1 FT #HET 65 94 GLY B 12 1212 SO4 B B 2 FT #HET 66 95 GLN B 13 1213 ACY B B 2 FT #HET 66 95 GLN B 14 1214 C5Q B A 5 FT #HET 67 96 GLU B 13 1213 ACY B A 6 FT #HET 69 98 ALA B 14 1214 C5Q B A 5 FT #HET 70 99 TYR B 5 1214 ACY A S 6 FT #HET 70 99 TYR B 13 1213 ACY B S 7 FT #HET 70 99 TYR B 14 1214 C5Q B A 5 FT #HET 73 102 LEU B 14 1214 C5Q B S 1 FT #HET 74 103 LYS B 5 1214 ACY A S 3 FT #HET 76 105 ALA B 8 1217 C5Q A B 1 FT #HET 77 106 GLY B 8 1217 C5Q A B 1 FT #HET 78 107 ARG B 7 1216 EDO A S 3 FT #HET 78 107 ARG B 8 1217 C5Q A B 2 FT #HET 79 108 TRP B 8 1217 C5Q A B 7 FT #HET 80 109 PRO B 8 1217 C5Q A A 9 FT #HET 94 123 SER B 12 1212 SO4 B A 6 FT #HET 95 124 THR B 12 1212 SO4 B A 5 FT #HET 96 125 THR B 12 1212 SO4 B A 7 FT #HET 96 125 THR B 14 1214 C5Q B A 5 FT #HET 99 128 ALA B 14 1214 C5Q B A 4 FT #HET 100 129 ALA B 14 1214 C5Q B A 6 FT #HET 102 131 TRP B 14 1214 C5Q B S 3 FT #HET 103 132 TRP B 14 1214 C5Q B S 1 FT #HET 130 159 LYS B 10 1210 SO4 B S 4 FT #HET 137 166 ARG B 11 1211 SO4 B S 1 FT #HET 139 168 GLN B 9 1218 C5Q A B 5 FT #HET 141 170 GLU B 11 1211 SO4 B B 1 FT #HET 142 171 HIS B 11 1211 SO4 B A 10 FT #HET 143 172 LEU B 11 1211 SO4 B A 5 FT #HET 144 173 LYS B 6 1215 ACY A S 2 FT #HET 145 174 THR B 9 1218 C5Q A S 2 FT #HET 149 178 MET B 9 1218 C5Q A S 3 FT #HET 156 185 HIS B 15 1215 C5Q B A 13 FT #HET 158 187 ARG B 15 1215 C5Q B S 2 FT #HET 166 195 SER B 15 1215 C5Q B S 3 FT #HET 168 197 GLY B 15 1215 C5Q B B 9 FT #HET 169 198 GLU B 15 1215 C5Q B B 3 FT DISORDER 1 27 FT DISORDER 160 164 FT DISORDER 181 183 CC SEQUENCE 148 AA (ATOM); CC SPGIWQLDCT HLEGKVILVA VHVASGYIEA EVIPAETGQE TAYFLLKLAG RWPVKTVHTD CC NGSNFTSTTV KAACWWAGIK QEDGIPYNPQ SQGVIESMNK ELKKIIGQVR DQAEHLKTAV CC QMAVFIHNHK RKYSAGERIV DIIATDIQ CC !---- CC ALIGNMENT OF SEQRES AND ATOMRES CC SEQRES MGSSHHHHHHSSGLVPRGSHMHGQVDSSPGIWQLDCTHLEGKVILVAVHV CC ATOM ---------------------------SPGIWQLDCTHLEGKVILVAVHV CC *********************** CC SEQRES ASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAA CC ATOM ASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSNFTSTTVKAA CC ************************************************** CC SEQRES CWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMA CC ATOM CWWAGIKQEDGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMA CC ************************************************** CC SEQRES VFIHNHKRKGGIGGYSAGERIVDIIATDIQTKE CC ATOM VFIHNHKRK-----YSAGERIVDIIATDIQ--- CC ********* **************** SQ SEQUENCE 183 AA; MW; CN; MGSSHHHHHH SSGLVPRGSH MHGQVDSSPG IWQLDCTHLE GKVILVAVHV ASGYIEAEVI PAETGQETAY FLLKLAGRWP VKTVHTDNGS NFTSTTVKAA CWWAGIKQED GIPYNPQSQG VIESMNKELK KIIGQVRDQA EHLKTAVQMA VFIHNHKRKG GIGGYSAGER IVDIIATDIQ TKE //