ID	4B00A	STANDARD;	PRT;	411	AA.
DT	CONVERTED FROM PDB (SEQRES) 4B00
DE	BETA-SECRETASE 1
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.830
CC	R-Factor	0.176
FT	#HET	29	  10 	SER	A	5	1507 	I6X	A	B	2
FT	#HET	30	  11 	GLY	A	5	1507 	I6X	A	B	1
FT	#HET	31	  12 	GLN	A	5	1507 	I6X	A	B	3
FT	#HET	32	  13 	GLY	A	5	1507 	I6X	A	B	5
FT	#HET	49	  30 	LEU	A	5	1507 	I6X	A	S	1
FT	#HET	51	  32 	ASP	A	5	1507 	I6X	A	S	12
FT	#HET	53	  34 	GLY	A	5	1507 	I6X	A	B	2
FT	#HET	54	  35 	SER	A	5	1507 	I6X	A	S	6
FT	#HET	85	  66 	GLY	A	3	1505 	ACT	A	B	4
FT	#HET	86	  67 	VAL	A	3	1505 	ACT	A	B	1
FT	#HET	87	  68 	TYR	A	3	1505 	ACT	A	S	1
FT	#HET	88	  69 	VAL	A	5	1507 	I6X	A	S	3
FT	#HET	90	  71 	TYR	A	5	1507 	I6X	A	S	6
FT	#HET	92	  73 	GLN	A	5	1507 	I6X	A	S	2
FT	#HET	95	  76 	TRP	A	5	1507 	I6X	A	S	5
FT	#HET	96	  77 	GLU	A	3	1505 	ACT	A	S	3
FT	#HET	112	  93 	VAL	A	4	1506 	ACT	A	B	2
FT	#HET	113	  94 	THR	A	4	1506 	ACT	A	A	3
FT	#HET	127	 108 	PHE	A	5	1507 	I6X	A	A	6
FT	#HET	129	 110 	ILE	A	5	1507 	I6X	A	S	4
FT	#HET	134	 115 	TRP	A	5	1507 	I6X	A	S	1
FT	#HET	137	 118 	ILE	A	5	1507 	I6X	A	S	5
FT	#HET	207	 188 	LEU	A	2	1504 	ACT	A	B	3
FT	#HET	208	 189 	TRP	A	2	1504 	ACT	A	S	10
FT	#HET	217	 198 	TYR	A	1	1503 	ACT	A	S	6
FT	#HET	243	 224 	LYS	A	1	1503 	ACT	A	S	3
FT	#HET	247	 228 	ASP	A	5	1507 	I6X	A	S	4
FT	#HET	248	 229 	SER	A	5	1507 	I6X	A	B	2
FT	#HET	249	 230 	GLY	A	5	1507 	I6X	A	B	13
FT	#HET	250	 231 	THR	A	5	1507 	I6X	A	A	4
FT	#HET	251	 232 	THR	A	5	1507 	I6X	A	S	1
FT	#HET	348	 329 	THR	A	1	1503 	ACT	A	S	3
FT	#HET	354	 335 	ALA	A	5	1507 	I6X	A	S	1
FT	DISORDER	1	15
FT	DISORDER	177	189
FT	DISORDER	404	411
CC	SEQUENCE	375 AA (ATOM);
CC	GSFVEMVDNL RGKSGQGYYV EMTVGSPPQT LNILVDTGSS NFAVGAAPHP FLHRYYQRQL
CC	SSTYRDLRKG VYVPYTQGKW EGELGTDLVS IPHGPNVTVR ANIAAITESD KFFINGSNWE
CC	GILGLAYAEI ARPDDSLEPF FDSLVKQTHV PNLFSLQLCG AGGSMIIGGI DHSLYTGSLW
CC	YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK VFEAAVKSIK
CC	AASSTEKFPD GFWLGEQLVC WQAGTTPWNI FPVISLYLMG EVTNQSFRIT ILPQQYLRPV
CC	EDVATSQDDC YKFAISQSST GTVMGAVIME GFYVVFDRAR KRIGFAVSAC HVHDEFRTAA
CC	VEGPFVTLDM EDCGY
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES LPRETDEEPEEPGKKGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILV
CC	ATOM   ---------------GSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILV
CC	                      ***********************************
CC	SEQRES DTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELG
CC	ATOM   DTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELG
CC	       **************************************************
CC	SEQRES TDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDD
CC	ATOM   TDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDD
CC	       **************************************************
CC	SEQRES SLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDH
CC	ATOM   SLEPFFDSLVKQTHVPNLFSLQLCGA-------------GGSMIIGGIDH
CC	       **************************             ***********
CC	SEQRES SLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGT
CC	ATOM   SLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGT
CC	       **************************************************
CC	SEQRES TNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFP
CC	ATOM   TNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFP
CC	       **************************************************
CC	SEQRES VISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGT
CC	ATOM   VISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGT
CC	       **************************************************
CC	SEQRES VMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMED
CC	ATOM   VMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMED
CC	       **************************************************
CC	SEQRES CGYNIPQTDES
CC	ATOM   CGY--------
CC	       ***        
SQ	SEQUENCE	411 AA;      MW;         CN;
	LPRETDEEPE EPGKKGSFVE MVDNLRGKSG QGYYVEMTVG SPPQTLNILV DTGSSNFAVG
	AAPHPFLHRY YQRQLSSTYR DLRKGVYVPY TQGKWEGELG TDLVSIPHGP NVTVRANIAA
	ITESDKFFIN GSNWEGILGL AYAEIARPDD SLEPFFDSLV KQTHVPNLFS LQLCGAGFPL
	NQSEVLASVG GSMIIGGIDH SLYTGSLWYT PIRREWYYEV IIVRVEINGQ DLKMDCKEYN
	YDKSIVDSGT TNLRLPKKVF EAAVKSIKAA SSTEKFPDGF WLGEQLVCWQ AGTTPWNIFP
	VISLYLMGEV TNQSFRITIL PQQYLRPVED VATSQDDCYK FAISQSSTGT VMGAVIMEGF
	YVVFDRARKR IGFAVSACHV HDEFRTAAVE GPFVTLDMED CGYNIPQTDE S
//