ID	3WB5A	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 3WB5
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.500
CC	R-Factor	0.204
FT	#HET	32	   9 	LYS	A	5	505 	GOL	A	B	1
FT	#HET	33	  10 	SER	A	5	505 	GOL	A	B	1
FT	#HET	34	  11 	GLY	A	5	505 	GOL	A	B	8
FT	#HET	34	  11 	GLY	A	6	506 	DMS	A	B	1
FT	#HET	35	  12 	GLN	A	5	505 	GOL	A	B	1
FT	#HET	35	  12 	GLN	A	6	506 	DMS	A	B	1
FT	#HET	36	  13 	GLY	A	5	505 	GOL	A	B	4
FT	#HET	36	  13 	GLY	A	6	506 	DMS	A	B	4
FT	#HET	37	  14 	TYR	A	5	505 	GOL	A	S	6
FT	#HET	53	  30 	LEU	A	6	506 	DMS	A	S	1
FT	#HET	53	  30 	LEU	A	7	507 	0B4	A	S	1
FT	#HET	55	  32 	ASP	A	7	507 	0B4	A	S	11
FT	#HET	57	  34 	GLY	A	7	507 	0B4	A	B	3
FT	#HET	58	  35 	SER	A	7	507 	0B4	A	S	2
FT	#HET	68	  45 	HIS	A	2	502 	IOD	A	S	1
FT	#HET	94	  71 	TYR	A	7	507 	0B4	A	S	5
FT	#HET	119	  96 	ARG	A	1	501 	IOD	A	B	1
FT	#HET	127	 104 	GLU	A	2	502 	IOD	A	B	3
FT	#HET	128	 105 	SER	A	2	502 	IOD	A	A	2
FT	#HET	131	 108 	PHE	A	7	507 	0B4	A	A	6
FT	#HET	141	 118 	ILE	A	7	507 	0B4	A	S	1
FT	#HET	157	 134 	GLU	A	1	501 	IOD	A	S	1
FT	#HET	166	 143 	GLN	A	1	501 	IOD	A	S	1
FT	#HET	193	 170 	VAL	A	5	505 	GOL	A	S	2
FT	#HET	204	 181 	HIS	A	4	504 	GOL	A	B	3
FT	#HET	207	 184 	TYR	A	4	504 	GOL	A	A	12
FT	#HET	208	 185 	THR	A	4	504 	GOL	A	B	2
FT	#HET	209	 186 	GLY	A	4	504 	GOL	A	B	6
FT	#HET	251	 228 	ASP	A	7	507 	0B4	A	S	5
FT	#HET	253	 230 	GLY	A	6	506 	DMS	A	B	5
FT	#HET	253	 230 	GLY	A	7	507 	0B4	A	B	1
FT	#HET	254	 231 	THR	A	7	507 	0B4	A	S	1
FT	#HET	255	 232 	THR	A	5	505 	GOL	A	S	1
FT	#HET	255	 232 	THR	A	6	506 	DMS	A	S	2
FT	#HET	358	 335 	ALA	A	5	505 	GOL	A	S	1
FT	#HET	362	 339 	GLU	A	5	505 	GOL	A	S	5
FT	#HET	372	 349 	ARG	A	3	503 	IOD	A	S	1
FT	DISORDER	1	21
FT	DISORDER	180	190
FT	DISORDER	297	299
FT	DISORDER	332	342
FT	DISORDER	387	387
FT	DISORDER	409	416
CC	Miss-SC	4
CC	SEQUENCE	361 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAS VGGSMIIGGI DHSLYTGSLW
CC	YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK VFEAAVKSIK
CC	AASSTEKFPD GFWLGEQLVC WQAGWNIFPV ISLYLMGEVT NQSFRITILP QQYLRPYKFA
CC	ISQSSTGTVM GAVIMEGFYV VFDRARKRIG FAVSACHVHD FRTAAVEGPF VTLDMEDCGY
CC	N
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ---------------------FVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                            *****************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCG-----------ASVGGSMIIG
CC	       *****************************           **********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAG---W
CC	       **********************************************   *
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRP-----------YKFAISQS
CC	       *******************************           ********
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHD-FRTAAVEGPFVTL
CC	       ************************************ *************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYN--------
CC	       ********        
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//