ID	3WB4A	STANDARD;	PRT;	416	AA.
DT	CONVERTED FROM PDB (SEQRES) 3WB4
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.213
FT	#HET	32	   9 	LYS	A	1	501 	GOL	A	B	1
FT	#HET	33	  10 	SER	A	1	501 	GOL	A	B	3
FT	#HET	34	  11 	GLY	A	1	501 	GOL	A	B	8
FT	#HET	35	  12 	GLN	A	1	501 	GOL	A	B	2
FT	#HET	36	  13 	GLY	A	1	501 	GOL	A	B	4
FT	#HET	37	  14 	TYR	A	1	501 	GOL	A	S	1
FT	#HET	40	  17 	GLU	A	2	502 	GOL	A	S	5
FT	#HET	49	  26 	THR	A	2	502 	GOL	A	S	3
FT	#HET	51	  28 	ASN	A	2	502 	GOL	A	S	7
FT	#HET	53	  30 	LEU	A	7	507 	0B3	A	S	2
FT	#HET	55	  32 	ASP	A	7	507 	0B3	A	S	10
FT	#HET	57	  34 	GLY	A	7	507 	0B3	A	B	1
FT	#HET	58	  35 	SER	A	7	507 	0B3	A	S	1
FT	#HET	73	  50 	ARG	A	2	502 	GOL	A	S	8
FT	#HET	73	  50 	ARG	A	3	503 	GOL	A	A	4
FT	#HET	74	  51 	TYR	A	3	503 	GOL	A	A	9
FT	#HET	76	  53 	GLN	A	3	503 	GOL	A	S	3
FT	#HET	94	  71 	TYR	A	7	507 	0B3	A	S	7
FT	#HET	98	  75 	LYS	A	6	506 	IOD	A	S	1
FT	#HET	119	  96 	ARG	A	5	505 	IOD	A	B	1
FT	#HET	127	 104 	GLU	A	6	506 	IOD	A	S	1
FT	#HET	131	 108 	PHE	A	7	507 	0B3	A	B	1
FT	#HET	133	 110 	ILE	A	7	507 	0B3	A	S	1
FT	#HET	137	 114 	ASN	A	2	502 	GOL	A	S	1
FT	#HET	138	 115 	TRP	A	7	507 	0B3	A	S	1
FT	#HET	141	 118 	ILE	A	7	507 	0B3	A	S	1
FT	#HET	193	 170 	VAL	A	1	501 	GOL	A	S	1
FT	#HET	204	 181 	HIS	A	4	504 	GOL	A	A	8
FT	#HET	207	 184 	TYR	A	4	504 	GOL	A	A	8
FT	#HET	209	 186 	GLY	A	4	504 	GOL	A	B	3
FT	#HET	251	 228 	ASP	A	7	507 	0B3	A	S	6
FT	#HET	253	 230 	GLY	A	7	507 	0B3	A	B	3
FT	#HET	254	 231 	THR	A	7	507 	0B3	A	S	1
FT	#HET	255	 232 	THR	A	1	501 	GOL	A	S	1
FT	#HET	358	 335 	ALA	A	1	501 	GOL	A	S	2
FT	#HET	362	 339 	GLU	A	1	501 	GOL	A	S	3
FT	DISORDER	1	21
FT	DISORDER	181	190
FT	DISORDER	275	277
FT	DISORDER	296	300
FT	DISORDER	333	341
FT	DISORDER	409	416
CC	Miss-SC	1
CC	SEQUENCE	360 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAA SVGGSMIIGG IDHSLYTGSL
CC	WYTPIRREWY YEVIIVRVEI NGQDLKMDCK EYNYDKSIVD SGTTNLRLPK KVFEAAVKSI
CC	KAAEKFPDGF WLGEQLVCWQ ANIFPVISLY LMGEVTNQSF RITILPQQYL RPVCYKFAIS
CC	QSSTGTVMGA VIMEGFYVVF DRARKRIGFA VSACHVHDEF RTAAVEGPFV TLDMEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSHMLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	ATOM   ---------------------FVEMVDNLRGKSGQGYYVEMTVGSPPQTL
CC	                            *****************************
CC	SEQRES NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	ATOM   NILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWE
CC	       **************************************************
CC	SEQRES GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	ATOM   GELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIA
CC	       **************************************************
CC	SEQRES RPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIG
CC	ATOM   RPDDSLEPFFDSLVKQTHVPNLFSLQLCGA----------ASVGGSMIIG
CC	       ******************************          **********
CC	SEQRES GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	ATOM   GIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIV
CC	       **************************************************
CC	SEQRES DSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPW
CC	ATOM   DSGTTNLRLPKKVFEAAVKSIKAA---EKFPDGFWLGEQLVCWQA-----
CC	       ************************   ******************     
CC	SEQRES NIFPVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQS
CC	ATOM   NIFPVISLYLMGEVTNQSFRITILPQQYLRPV---------CYKFAISQS
CC	       ********************************         *********
CC	SEQRES STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	ATOM   STGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTL
CC	       **************************************************
CC	SEQRES DMEDCGYNIPQTDEST
CC	ATOM   DMEDCGYN--------
CC	       ********        
SQ	SEQUENCE	416 AA;      MW;         CN;
	GSHMLPRETD EEPEEPGRRG SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN
	FAVGAAPHPF LHRYYQRQLS STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA
	NIAAITESDK FFINGSNWEG ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA
	GFPLNQSEVL ASVGGSMIIG GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC
	KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW
	NIFPVISLYL MGEVTNQSFR ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI
	MEGFYVVFDR ARKRIGFAVS ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDEST
//