ID	3VQSA	STANDARD;	PRT;	578	AA.
DT	CONVERTED FROM PDB (SEQRES) 3VQS
DE	RNA-directed RNA polymerase
OS	Hepatitis C virus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.172
FT	#SUB	184	 184 	GLN	A	531	 531 	LYS	C	Protein	S	2
FT	#SUB	189	 189 	SER	A	532	 532 	THR	C	Protein	A	2
FT	#SUB	194	 194 	GLN	A	531	 531 	LYS	C	Protein	S	6
FT	#SUB	202	 202 	GLU	A	502	 502 	HIS	C	Protein	S	9
FT	#SUB	202	 202 	GLU	A	505	 505 	ARG	C	Protein	S	6
FT	#SUB	206	 206 	ASN	A	505	 505 	ARG	C	Protein	S	4
FT	#SUB	206	 206 	ASN	A	506	 506 	SER	C	Protein	S	3
FT	#SUB	206	 206 	ASN	A	509	 509 	ALA	C	Protein	B	1
FT	#SUB	209	 209 	LYS	A	506	 506 	SER	C	Protein	S	1
FT	#SUB	209	 209 	LYS	A	509	 509 	ALA	C	Protein	B	1
FT	#SUB	209	 209 	LYS	A	513	 513 	SER	C	Protein	B	2
FT	#SUB	210	 210 	SER	A	509	 509 	ALA	C	Protein	A	3
FT	#SUB	210	 210 	SER	A	512	 512 	LEU	C	Protein	B	1
FT	#SUB	210	 210 	SER	A	513	 513 	SER	C	Protein	B	5
FT	#SUB	211	 211 	LYS	A	513	 513 	SER	C	Protein	B	2
FT	#SUB	212	 212 	LYS	A	512	 512 	LEU	C	Protein	S	1
FT	#SUB	212	 212 	LYS	A	513	 513 	SER	C	Protein	A	5
FT	#SUB	212	 212 	LYS	A	515	 515 	GLY	C	Protein	S	1
FT	#SUB	538	 538 	PRO	A	498	 498 	ARG	C	Protein	S	2
FT	#SUB	502	 502 	HIS	A	202	 202 	GLU	D	Protein	A	8
FT	#SUB	505	 505 	ARG	A	202	 202 	GLU	D	Protein	S	6
FT	#SUB	505	 505 	ARG	A	206	 206 	ASN	D	Protein	A	4
FT	#SUB	506	 506 	SER	A	206	 206 	ASN	D	Protein	A	3
FT	#SUB	509	 509 	ALA	A	206	 206 	ASN	D	Protein	S	1
FT	#SUB	509	 509 	ALA	A	209	 209 	LYS	D	Protein	B	2
FT	#SUB	509	 509 	ALA	A	210	 210 	SER	D	Protein	A	6
FT	#SUB	512	 512 	LEU	A	210	 210 	SER	D	Protein	B	1
FT	#SUB	512	 512 	LEU	A	212	 212 	LYS	D	Protein	B	1
FT	#SUB	513	 513 	SER	A	209	 209 	LYS	D	Protein	S	2
FT	#SUB	513	 513 	SER	A	210	 210 	SER	D	Protein	A	5
FT	#SUB	513	 513 	SER	A	211	 211 	LYS	D	Protein	S	2
FT	#SUB	513	 513 	SER	A	212	 212 	LYS	D	Protein	B	3
FT	#SUB	515	 515 	GLY	A	212	 212 	LYS	D	Protein	B	2
FT	#SUB	531	 531 	LYS	A	184	 184 	GLN	D	Protein	S	2
FT	#SUB	531	 531 	LYS	A	194	 194 	GLN	D	Protein	S	4
FT	#SUB	532	 532 	THR	A	188	 188 	GLY	D	Protein	S	2
FT	#SUB	532	 532 	THR	A	189	 189 	SER	D	Protein	A	6
FT	#HET	179	 179 	VAL	A	1	1000 	JT1	A	A	5
FT	#HET	191	 191 	TYR	A	1	1000 	JT1	A	S	4
FT	#HET	192	 192 	GLY	A	1	1000 	JT1	A	B	1
FT	#HET	193	 193 	PHE	A	1	1000 	JT1	A	A	25
FT	#HET	195	 195 	TYR	A	1	1000 	JT1	A	B	10
FT	#HET	196	 196 	SER	A	1	1000 	JT1	A	A	6
FT	#HET	197	 197 	PRO	A	1	1000 	JT1	A	A	7
FT	#HET	200	 200 	ARG	A	1	1000 	JT1	A	S	7
FT	#HET	288	 288 	SER	A	1	1000 	JT1	A	S	8
FT	#HET	289	 289 	CYS	A	1	1000 	JT1	A	A	3
FT	#HET	316	 316 	ASN	A	1	1000 	JT1	A	S	4
FT	#HET	366	 366 	CYS	A	1	1000 	JT1	A	S	2
FT	#HET	368	 368 	SER	A	1	1000 	JT1	A	S	4
FT	#HET	384	 384 	LEU	A	1	1000 	JT1	A	S	4
FT	#HET	413	 413 	ILE	A	1	1000 	JT1	A	S	1
FT	#HET	414	 414 	MET	A	1	1000 	JT1	A	A	7
FT	#HET	415	 415 	TYR	A	1	1000 	JT1	A	S	6
FT	#HET	447	 447 	ILE	A	1	1000 	JT1	A	A	6
FT	#HET	448	 448 	TYR	A	1	1000 	JT1	A	A	15
FT	#HET	450	 450 	ALA	A	1	1000 	JT1	A	A	2
FT	#HET	452	 452 	TYR	A	1	1000 	JT1	A	S	23
FT	#HET	454	 454 	ILE	A	1	1000 	JT1	A	S	2
FT	#HET	462	 462 	ILE	A	1	1000 	JT1	A	S	1
FT	#HET	466	 466 	LEU	A	1	1000 	JT1	A	S	6
FT	#HET	547	 547 	LEU	A	1	1000 	JT1	A	A	4
FT	#HET	551	 551 	PHE	A	1	1000 	JT1	A	S	10
FT	DISORDER	554	578
CC	SEQUENCE	553 AA (ATOM);
CC	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
CC	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
CC	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
CC	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
CC	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
CC	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
CC	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
CC	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
CC	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
CC	AASQLDLSGW FVA
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	ATOM   SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	       **************************************************
CC	SEQRES KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	ATOM   KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	       **************************************************
CC	SEQRES FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	ATOM   FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	       **************************************************
CC	SEQRES KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	ATOM   KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	       **************************************************
CC	SEQRES VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	ATOM   VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	       **************************************************
CC	SEQRES QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	ATOM   QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	       **************************************************
CC	SEQRES AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	ATOM   AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	       **************************************************
CC	SEQRES GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	ATOM   GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	       **************************************************
CC	SEQRES RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	ATOM   RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	       **************************************************
CC	SEQRES CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	ATOM   CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	       **************************************************
CC	SEQRES RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	ATOM   RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	       **************************************************
CC	SEQRES FVAGYSGGDIYHSLSRARPRGSHHHHHH
CC	ATOM   FVA-------------------------
CC	       ***                         
SQ	SEQUENCE	578 AA;      MW;         CN;
	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
	AASQLDLSGW FVAGYSGGDI YHSLSRARPR GSHHHHHH
//
ID	3VQSB	STANDARD;	PRT;	578	AA.
DT	CONVERTED FROM PDB (SEQRES) 3VQS
DE	RNA-directed RNA polymerase
OS	Hepatitis C virus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.172
FT	#SUB	307	 307 	LYS	B	151	 151 	LYS	C	Protein	S	3
FT	#SUB	338	 338 	VAL	B	149	 149 	PRO	C	Protein	S	1
FT	#SUB	345	 345 	ARG	B	150	 150 	GLU	C	Protein	S	1
FT	#SUB	149	 149 	PRO	B	338	 338 	VAL	D	Protein	B	1
FT	#SUB	150	 150 	GLU	B	341	 341 	GLU	D	Protein	S	1
FT	#SUB	150	 150 	GLU	B	345	 345 	ARG	D	Protein	S	2
FT	#SUB	151	 151 	LYS	B	307	 307 	LYS	D	Protein	B	2
FT	#HET	92	  92 	THR	B	3	602 	CL	B	S	1
FT	#HET	93	  93 	PRO	B	3	602 	CL	B	S	1
FT	#HET	96	  96 	SER	B	3	602 	CL	B	S	2
FT	#HET	168	 168 	ARG	B	3	602 	CL	B	S	5
FT	#HET	172	 172 	LYS	B	3	602 	CL	B	S	1
FT	#HET	179	 179 	VAL	B	2	601 	JT1	B	A	4
FT	#HET	191	 191 	TYR	B	2	601 	JT1	B	S	3
FT	#HET	192	 192 	GLY	B	2	601 	JT1	B	B	1
FT	#HET	193	 193 	PHE	B	2	601 	JT1	B	A	20
FT	#HET	195	 195 	TYR	B	2	601 	JT1	B	B	9
FT	#HET	196	 196 	SER	B	2	601 	JT1	B	A	6
FT	#HET	197	 197 	PRO	B	2	601 	JT1	B	A	7
FT	#HET	200	 200 	ARG	B	2	601 	JT1	B	S	6
FT	#HET	288	 288 	SER	B	2	601 	JT1	B	S	6
FT	#HET	289	 289 	CYS	B	2	601 	JT1	B	A	3
FT	#HET	316	 316 	ASN	B	2	601 	JT1	B	S	3
FT	#HET	366	 366 	CYS	B	2	601 	JT1	B	S	2
FT	#HET	368	 368 	SER	B	2	601 	JT1	B	S	4
FT	#HET	384	 384 	LEU	B	2	601 	JT1	B	S	5
FT	#HET	413	 413 	ILE	B	2	601 	JT1	B	S	1
FT	#HET	414	 414 	MET	B	2	601 	JT1	B	A	7
FT	#HET	415	 415 	TYR	B	2	601 	JT1	B	S	6
FT	#HET	447	 447 	ILE	B	2	601 	JT1	B	A	5
FT	#HET	448	 448 	TYR	B	2	601 	JT1	B	A	15
FT	#HET	450	 450 	ALA	B	2	601 	JT1	B	S	1
FT	#HET	452	 452 	TYR	B	2	601 	JT1	B	S	24
FT	#HET	454	 454 	ILE	B	2	601 	JT1	B	S	1
FT	#HET	462	 462 	ILE	B	2	601 	JT1	B	S	1
FT	#HET	466	 466 	LEU	B	2	601 	JT1	B	S	5
FT	#HET	547	 547 	LEU	B	2	601 	JT1	B	S	1
FT	#HET	555	 555 	TYR	B	2	601 	JT1	B	S	11
FT	#HET	556	 556 	SER	B	2	601 	JT1	B	S	1
FT	DISORDER	558	578
CC	SEQUENCE	557 AA (ATOM);
CC	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
CC	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
CC	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
CC	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
CC	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
CC	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
CC	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
CC	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
CC	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
CC	AASQLDLSGW FVAGYSG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	ATOM   SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	       **************************************************
CC	SEQRES KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	ATOM   KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	       **************************************************
CC	SEQRES FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	ATOM   FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	       **************************************************
CC	SEQRES KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	ATOM   KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	       **************************************************
CC	SEQRES VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	ATOM   VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	       **************************************************
CC	SEQRES QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	ATOM   QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	       **************************************************
CC	SEQRES AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	ATOM   AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	       **************************************************
CC	SEQRES GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	ATOM   GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	       **************************************************
CC	SEQRES RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	ATOM   RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	       **************************************************
CC	SEQRES CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	ATOM   CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	       **************************************************
CC	SEQRES RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	ATOM   RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	       **************************************************
CC	SEQRES FVAGYSGGDIYHSLSRARPRGSHHHHHH
CC	ATOM   FVAGYSG---------------------
CC	       *******                     
SQ	SEQUENCE	578 AA;      MW;         CN;
	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
	AASQLDLSGW FVAGYSGGDI YHSLSRARPR GSHHHHHH
//
ID	3VQSC	STANDARD;	PRT;	578	AA.
DT	CONVERTED FROM PDB (SEQRES) 3VQS
DE	RNA-directed RNA polymerase
OS	Hepatitis C virus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.172
FT	#SUB	498	 498 	ARG	C	538	 538 	PRO	A	Protein	S	2
FT	#SUB	502	 502 	HIS	C	202	 202 	GLU	A	Protein	A	9
FT	#SUB	505	 505 	ARG	C	202	 202 	GLU	A	Protein	S	6
FT	#SUB	505	 505 	ARG	C	206	 206 	ASN	A	Protein	A	4
FT	#SUB	506	 506 	SER	C	206	 206 	ASN	A	Protein	A	3
FT	#SUB	506	 506 	SER	C	209	 209 	LYS	A	Protein	S	1
FT	#SUB	509	 509 	ALA	C	206	 206 	ASN	A	Protein	S	1
FT	#SUB	509	 509 	ALA	C	209	 209 	LYS	A	Protein	B	1
FT	#SUB	509	 509 	ALA	C	210	 210 	SER	A	Protein	A	3
FT	#SUB	512	 512 	LEU	C	210	 210 	SER	A	Protein	B	1
FT	#SUB	512	 512 	LEU	C	212	 212 	LYS	A	Protein	B	1
FT	#SUB	513	 513 	SER	C	209	 209 	LYS	A	Protein	S	2
FT	#SUB	513	 513 	SER	C	210	 210 	SER	A	Protein	A	5
FT	#SUB	513	 513 	SER	C	211	 211 	LYS	A	Protein	S	2
FT	#SUB	513	 513 	SER	C	212	 212 	LYS	A	Protein	B	5
FT	#SUB	515	 515 	GLY	C	212	 212 	LYS	A	Protein	B	1
FT	#SUB	531	 531 	LYS	C	184	 184 	GLN	A	Protein	S	2
FT	#SUB	531	 531 	LYS	C	194	 194 	GLN	A	Protein	S	6
FT	#SUB	532	 532 	THR	C	189	 189 	SER	A	Protein	S	2
FT	#SUB	149	 149 	PRO	C	338	 338 	VAL	B	Protein	B	1
FT	#SUB	150	 150 	GLU	C	345	 345 	ARG	B	Protein	S	1
FT	#SUB	151	 151 	LYS	C	307	 307 	LYS	B	Protein	B	3
FT	#HET	92	  92 	THR	C	5	602 	CL	C	S	1
FT	#HET	93	  93 	PRO	C	5	602 	CL	C	S	1
FT	#HET	96	  96 	SER	C	5	602 	CL	C	S	2
FT	#HET	168	 168 	ARG	C	5	602 	CL	C	S	3
FT	#HET	172	 172 	LYS	C	5	602 	CL	C	S	1
FT	#HET	179	 179 	VAL	C	4	601 	JT1	C	A	4
FT	#HET	191	 191 	TYR	C	4	601 	JT1	C	S	3
FT	#HET	192	 192 	GLY	C	4	601 	JT1	C	B	1
FT	#HET	193	 193 	PHE	C	4	601 	JT1	C	A	21
FT	#HET	195	 195 	TYR	C	4	601 	JT1	C	B	10
FT	#HET	196	 196 	SER	C	4	601 	JT1	C	A	7
FT	#HET	197	 197 	PRO	C	4	601 	JT1	C	A	7
FT	#HET	200	 200 	ARG	C	4	601 	JT1	C	S	7
FT	#HET	288	 288 	SER	C	4	601 	JT1	C	S	6
FT	#HET	289	 289 	CYS	C	4	601 	JT1	C	A	4
FT	#HET	316	 316 	ASN	C	4	601 	JT1	C	S	3
FT	#HET	366	 366 	CYS	C	4	601 	JT1	C	S	2
FT	#HET	368	 368 	SER	C	4	601 	JT1	C	S	4
FT	#HET	384	 384 	LEU	C	4	601 	JT1	C	S	5
FT	#HET	413	 413 	ILE	C	4	601 	JT1	C	S	1
FT	#HET	414	 414 	MET	C	4	601 	JT1	C	A	7
FT	#HET	415	 415 	TYR	C	4	601 	JT1	C	S	6
FT	#HET	447	 447 	ILE	C	4	601 	JT1	C	A	4
FT	#HET	448	 448 	TYR	C	4	601 	JT1	C	A	15
FT	#HET	450	 450 	ALA	C	4	601 	JT1	C	S	2
FT	#HET	452	 452 	TYR	C	4	601 	JT1	C	S	24
FT	#HET	454	 454 	ILE	C	4	601 	JT1	C	S	1
FT	#HET	462	 462 	ILE	C	4	601 	JT1	C	S	1
FT	#HET	466	 466 	LEU	C	4	601 	JT1	C	S	4
FT	#HET	547	 547 	LEU	C	4	601 	JT1	C	S	2
FT	#HET	555	 555 	TYR	C	4	601 	JT1	C	S	9
FT	#HET	556	 556 	SER	C	4	601 	JT1	C	S	2
FT	DISORDER	557	578
CC	SEQUENCE	556 AA (ATOM);
CC	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
CC	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
CC	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
CC	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
CC	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
CC	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
CC	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
CC	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
CC	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
CC	AASQLDLSGW FVAGYS
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	ATOM   SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	       **************************************************
CC	SEQRES KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	ATOM   KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	       **************************************************
CC	SEQRES FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	ATOM   FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	       **************************************************
CC	SEQRES KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	ATOM   KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	       **************************************************
CC	SEQRES VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	ATOM   VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	       **************************************************
CC	SEQRES QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	ATOM   QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	       **************************************************
CC	SEQRES AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	ATOM   AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	       **************************************************
CC	SEQRES GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	ATOM   GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	       **************************************************
CC	SEQRES RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	ATOM   RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	       **************************************************
CC	SEQRES CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	ATOM   CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	       **************************************************
CC	SEQRES RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	ATOM   RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	       **************************************************
CC	SEQRES FVAGYSGGDIYHSLSRARPRGSHHHHHH
CC	ATOM   FVAGYS----------------------
CC	       ******                      
SQ	SEQUENCE	578 AA;      MW;         CN;
	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
	AASQLDLSGW FVAGYSGGDI YHSLSRARPR GSHHHHHH
//
ID	3VQSD	STANDARD;	PRT;	578	AA.
DT	CONVERTED FROM PDB (SEQRES) 3VQS
DE	RNA-directed RNA polymerase
OS	Hepatitis C virus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.172
FT	#SUB	184	 184 	GLN	D	531	 531 	LYS	A	Protein	S	2
FT	#SUB	188	 188 	GLY	D	532	 532 	THR	A	Protein	B	2
FT	#SUB	189	 189 	SER	D	532	 532 	THR	A	Protein	A	6
FT	#SUB	194	 194 	GLN	D	531	 531 	LYS	A	Protein	S	4
FT	#SUB	202	 202 	GLU	D	502	 502 	HIS	A	Protein	S	8
FT	#SUB	202	 202 	GLU	D	505	 505 	ARG	A	Protein	S	6
FT	#SUB	206	 206 	ASN	D	505	 505 	ARG	A	Protein	S	4
FT	#SUB	206	 206 	ASN	D	506	 506 	SER	A	Protein	S	3
FT	#SUB	206	 206 	ASN	D	509	 509 	ALA	A	Protein	B	1
FT	#SUB	209	 209 	LYS	D	509	 509 	ALA	A	Protein	B	2
FT	#SUB	209	 209 	LYS	D	513	 513 	SER	A	Protein	B	2
FT	#SUB	210	 210 	SER	D	509	 509 	ALA	A	Protein	A	6
FT	#SUB	210	 210 	SER	D	512	 512 	LEU	A	Protein	B	1
FT	#SUB	210	 210 	SER	D	513	 513 	SER	A	Protein	B	5
FT	#SUB	211	 211 	LYS	D	513	 513 	SER	A	Protein	B	2
FT	#SUB	212	 212 	LYS	D	512	 512 	LEU	A	Protein	S	1
FT	#SUB	212	 212 	LYS	D	513	 513 	SER	A	Protein	A	3
FT	#SUB	212	 212 	LYS	D	515	 515 	GLY	A	Protein	S	2
FT	#SUB	307	 307 	LYS	D	151	 151 	LYS	B	Protein	S	2
FT	#SUB	338	 338 	VAL	D	149	 149 	PRO	B	Protein	S	1
FT	#SUB	341	 341 	GLU	D	150	 150 	GLU	B	Protein	S	1
FT	#SUB	345	 345 	ARG	D	150	 150 	GLU	B	Protein	S	2
FT	#HET	179	 179 	VAL	D	6	1000 	JT1	D	A	4
FT	#HET	191	 191 	TYR	D	6	1000 	JT1	D	S	4
FT	#HET	192	 192 	GLY	D	6	1000 	JT1	D	B	1
FT	#HET	193	 193 	PHE	D	6	1000 	JT1	D	A	26
FT	#HET	195	 195 	TYR	D	6	1000 	JT1	D	B	10
FT	#HET	196	 196 	SER	D	6	1000 	JT1	D	A	6
FT	#HET	197	 197 	PRO	D	6	1000 	JT1	D	A	7
FT	#HET	200	 200 	ARG	D	6	1000 	JT1	D	S	7
FT	#HET	288	 288 	SER	D	6	1000 	JT1	D	S	8
FT	#HET	289	 289 	CYS	D	6	1000 	JT1	D	A	3
FT	#HET	316	 316 	ASN	D	6	1000 	JT1	D	S	4
FT	#HET	366	 366 	CYS	D	6	1000 	JT1	D	S	3
FT	#HET	368	 368 	SER	D	6	1000 	JT1	D	S	4
FT	#HET	384	 384 	LEU	D	6	1000 	JT1	D	S	4
FT	#HET	413	 413 	ILE	D	6	1000 	JT1	D	S	1
FT	#HET	414	 414 	MET	D	6	1000 	JT1	D	A	7
FT	#HET	415	 415 	TYR	D	6	1000 	JT1	D	S	6
FT	#HET	447	 447 	ILE	D	6	1000 	JT1	D	A	4
FT	#HET	448	 448 	TYR	D	6	1000 	JT1	D	A	13
FT	#HET	450	 450 	ALA	D	6	1000 	JT1	D	S	2
FT	#HET	452	 452 	TYR	D	6	1000 	JT1	D	S	22
FT	#HET	454	 454 	ILE	D	6	1000 	JT1	D	S	1
FT	#HET	462	 462 	ILE	D	6	1000 	JT1	D	S	1
FT	#HET	466	 466 	LEU	D	6	1000 	JT1	D	S	5
FT	#HET	547	 547 	LEU	D	6	1000 	JT1	D	A	6
FT	#HET	551	 551 	PHE	D	6	1000 	JT1	D	S	8
FT	DISORDER	554	578
CC	SEQUENCE	553 AA (ATOM);
CC	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
CC	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
CC	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
CC	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
CC	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
CC	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
CC	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
CC	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
CC	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
CC	AASQLDLSGW FVA
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	ATOM   SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	       **************************************************
CC	SEQRES KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	ATOM   KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	       **************************************************
CC	SEQRES FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	ATOM   FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	       **************************************************
CC	SEQRES KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	ATOM   KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	       **************************************************
CC	SEQRES VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	ATOM   VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	       **************************************************
CC	SEQRES QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	ATOM   QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	       **************************************************
CC	SEQRES AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	ATOM   AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	       **************************************************
CC	SEQRES GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	ATOM   GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	       **************************************************
CC	SEQRES RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	ATOM   RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	       **************************************************
CC	SEQRES CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	ATOM   CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	       **************************************************
CC	SEQRES RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	ATOM   RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKLTPIPAASQLDLSGW
CC	       **************************************************
CC	SEQRES FVAGYSGGDIYHSLSRARPRGSHHHHHH
CC	ATOM   FVA-------------------------
CC	       ***                         
SQ	SEQUENCE	578 AA;      MW;         CN;
	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKLTPIP
	AASQLDLSGW FVAGYSGGDI YHSLSRARPR GSHHHHHH
//