ID	3VF3A	STANDARD;	PRT;	402	AA.
DT	CONVERTED FROM PDB (SEQRES) 3VF3
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.480
CC	R-Factor	0.185
FT	#HET	28	  12 	GLN	A	1	401 	0GS	A	B	1
FT	#HET	46	  30 	LEU	A	1	401 	0GS	A	S	2
FT	#HET	48	  32 	ASP	A	1	401 	0GS	A	S	8
FT	#HET	50	  34 	GLY	A	1	401 	0GS	A	B	9
FT	#HET	51	  35 	SER	A	1	401 	0GS	A	A	4
FT	#HET	85	  69 	VAL	A	1	401 	0GS	A	S	1
FT	#HET	86	  70 	PRO	A	1	401 	0GS	A	B	1
FT	#HET	87	  71 	TYR	A	1	401 	0GS	A	A	12
FT	#HET	88	  72 	THR	A	1	401 	0GS	A	A	8
FT	#HET	89	  73 	GLN	A	1	401 	0GS	A	A	4
FT	#HET	90	  74 	GLY	A	1	401 	0GS	A	B	1
FT	#HET	123	 107 	LYS	A	1	401 	0GS	A	B	1
FT	#HET	124	 108 	PHE	A	1	401 	0GS	A	A	10
FT	#HET	126	 110 	ILE	A	1	401 	0GS	A	S	2
FT	#HET	131	 115 	TRP	A	1	401 	0GS	A	S	1
FT	#HET	134	 118 	ILE	A	1	401 	0GS	A	S	1
FT	#HET	142	 126 	ILE	A	1	401 	0GS	A	A	3
FT	#HET	144	 128 	ARG	A	1	401 	0GS	A	S	2
FT	#HET	214	 185 	TYR	A	1	401 	0GS	A	S	3
FT	#HET	244	 215 	ASP	A	1	401 	0GS	A	S	6
FT	#HET	246	 217 	GLY	A	1	401 	0GS	A	B	4
FT	#HET	247	 218 	THR	A	1	401 	0GS	A	S	3
FT	DISORDER	1	13
FT	DISORDER	172	173
FT	DISORDER	175	183
FT	DISORDER	185	186
FT	DISORDER	402	402
CC	SEQUENCE	375 AA (ATOM);
CC	SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN FAVGAAPHPF LHRYYQRQLS
CC	STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA NIAAITESDK FFINGSNWEG
CC	ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA GGSMIIGGID HSLYTGSLWY
CC	TPIRREWYYE VIIVRVEING QDLKMDCKEY NYDKSIVDSG TTNLRLPKKV FEAAVKSIKA
CC	ASSTEKFPDG FWLGEQLVCW QAGTTPWNIF PVISLYLMGE VTNQSFRITI LPQQYLRPVE
CC	DVATSQDDCY KFAISQSSTG TVMGAVIMEG FYVVFDRARK RIGFAVSACH VHDEFRTAAV
CC	EGPFVTLDME DCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GPDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTG
CC	ATOM   -------------SFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTG
CC	                    *************************************
CC	SEQRES SSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL
CC	ATOM   SSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDL
CC	       **************************************************
CC	SEQRES VSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLE
CC	ATOM   VSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLE
CC	       **************************************************
CC	SEQRES PFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLY
CC	ATOM   PFFDSLVKQTHVPNLFSLQLC--G---------A--GGSMIIGGIDHSLY
CC	       *********************  *         *  **************
CC	SEQRES TGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNL
CC	ATOM   TGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNL
CC	       **************************************************
CC	SEQRES RLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVIS
CC	ATOM   RLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVIS
CC	       **************************************************
CC	SEQRES LYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMG
CC	ATOM   LYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMG
CC	       **************************************************
CC	SEQRES AVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY
CC	ATOM   AVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGY
CC	       **************************************************
CC	SEQRES NI
CC	ATOM   N-
CC	       * 
SQ	SEQUENCE	402 AA;      MW;         CN;
	GPDEEPEEPG RRGSFVEMVD NLRGKSGQGY YVEMTVGSPP QTLNILVDTG SSNFAVGAAP
	HPFLHRYYQR QLSSTYRDLR KGVYVPYTQG KWEGELGTDL VSIPHGPNVT VRANIAAITE
	SDKFFINGSN WEGILGLAYA EIARPDDSLE PFFDSLVKQT HVPNLFSLQL CGAGFPLNQS
	EVLASVGGSM IIGGIDHSLY TGSLWYTPIR REWYYEVIIV RVEINGQDLK MDCKEYNYDK
	SIVDSGTTNL RLPKKVFEAA VKSIKAASST EKFPDGFWLG EQLVCWQAGT TPWNIFPVIS
	LYLMGEVTNQ SFRITILPQQ YLRPVEDVAT SQDDCYKFAI SQSSTGTVMG AVIMEGFYVV
	FDRARKRIGF AVSACHVHDE FRTAAVEGPF VTLDMEDCGY NI
//