ID	3UA1A	STANDARD;	PRT;	487	AA.
DT	CONVERTED FROM PDB (SEQRES) 3UA1
DE	Cytochrome P450 3A4
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.150
CC	R-Factor	0.224
FT	#HET	33	  53 	TYR	A	2	600 	08Y	A	S	1
FT	#HET	37	  57 	PHE	A	2	600 	08Y	A	S	7
FT	#HET	56	  76 	ASP	A	2	600 	08Y	A	S	3
FT	#HET	85	 105 	ARG	A	1	508 	HEM	A	S	15
FT	#HET	85	 105 	ARG	A	2	600 	08Y	A	S	4
FT	#HET	86	 106 	ARG	A	2	600 	08Y	A	S	14
FT	#HET	87	 107 	PRO	A	2	600 	08Y	A	B	1
FT	#HET	88	 108 	PHE	A	2	600 	08Y	A	S	3
FT	#HET	98	 118 	ILE	A	1	508 	HEM	A	A	4
FT	#HET	99	 119 	SER	A	1	508 	HEM	A	A	2
FT	#HET	99	 119 	SER	A	2	600 	08Y	A	S	3
FT	#HET	100	 120 	ILE	A	2	600 	08Y	A	S	2
FT	#HET	106	 126 	TRP	A	1	508 	HEM	A	S	6
FT	#HET	110	 130 	ARG	A	1	508 	HEM	A	S	4
FT	#HET	117	 137 	PHE	A	1	508 	HEM	A	S	2
FT	#HET	192	 212 	ARG	A	2	600 	08Y	A	S	3
FT	#HET	195	 215 	PHE	A	2	600 	08Y	A	S	11
FT	#HET	204	 224 	THR	A	2	600 	08Y	A	S	3
FT	#HET	282	 302 	PHE	A	1	508 	HEM	A	S	3
FT	#HET	284	 304 	PHE	A	2	600 	08Y	A	S	2
FT	#HET	285	 305 	ALA	A	1	508 	HEM	A	A	4
FT	#HET	285	 305 	ALA	A	2	600 	08Y	A	A	4
FT	#HET	286	 306 	GLY	A	1	508 	HEM	A	B	2
FT	#HET	289	 309 	THR	A	1	508 	HEM	A	A	4
FT	#HET	289	 309 	THR	A	2	600 	08Y	A	S	1
FT	#HET	290	 310 	THR	A	1	508 	HEM	A	A	3
FT	#HET	350	 370 	ALA	A	1	508 	HEM	A	S	1
FT	#HET	350	 370 	ALA	A	2	600 	08Y	A	S	1
FT	#HET	352	 372 	ARG	A	2	600 	08Y	A	A	4
FT	#HET	353	 373 	LEU	A	1	508 	HEM	A	S	2
FT	#HET	355	 375 	ARG	A	1	508 	HEM	A	S	8
FT	#HET	414	 434 	PRO	A	1	508 	HEM	A	B	3
FT	#HET	415	 435 	PHE	A	1	508 	HEM	A	A	8
FT	#HET	416	 436 	GLY	A	1	508 	HEM	A	B	3
FT	#HET	417	 437 	SER	A	1	508 	HEM	A	B	2
FT	#HET	420	 440 	ARG	A	1	508 	HEM	A	A	13
FT	#HET	421	 441 	ASN	A	1	508 	HEM	A	B	5
FT	#HET	422	 442 	CYS	A	1	508 	HEM	A	A	20
FT	#HET	423	 443 	ILE	A	1	508 	HEM	A	S	2
FT	#HET	424	 444 	GLY	A	1	508 	HEM	A	B	3
FT	#HET	427	 447 	PHE	A	1	508 	HEM	A	S	1
FT	#HET	428	 448 	ALA	A	1	508 	HEM	A	S	3
FT	DISORDER	1	7
FT	DISORDER	239	241
FT	DISORDER	246	248
FT	DISORDER	260	266
FT	DISORDER	477	487
CC	SEQUENCE	456 AA (ATOM);
CC	HSHGLFKKLG IPGPTPLPFL GNILSYHKGF CMFDMECHKK YGKVWGFYDG QQPVLAITDP
CC	DMIKTVLVKE CYSVFTNRRP FGPVGFMKSA ISIAEDEEWK RLRSLLSPTF TSGKLKEMVP
CC	IIAQYGDVLV RNLRREAETG KPVTLKDVFG AYSMDVITST SFGVNIDSLN NPQDPFVENT
CC	KKLLRFDFLD PFFLSITVFP FLIPILEVLN ICVFPREVTN FLRKSVKRMK EEDTQVDFLQ
CC	LMIDSQHKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE LATHPDVQQK LQEEIDAVLP
CC	NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVCKKD VEINGMFIPK GVVVMIPSYA
CC	LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR NCIGMRFALM NMKLALIRVL
CC	QNFSFKPCKE TQIPLKLSLG GLLQPEKPVV LKVESR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	ATOM   -------HSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMECHKKYGK
CC	              *******************************************
CC	SEQRES VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	ATOM   VWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISI
CC	       **************************************************
CC	SEQRES AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	ATOM   AEDEEWKRLRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPV
CC	       **************************************************
CC	SEQRES TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	ATOM   TLKDVFGAYSMDVITSTSFGVNIDSLNNPQDPFVENTKKLLRFDFLDPFF
CC	       **************************************************
CC	SEQRES LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKESRLEDTQKHRVD
CC	ATOM   LSITVFPFLIPILEVLNICVFPREVTNFLRKSVKRMKE---EDTQ---VD
CC	       **************************************   ****   **
CC	SEQRES FLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	ATOM   FLQLMIDSQ-------HKALSDLELVAQSIIFIFAGYETTSSVLSFIMYE
CC	       *********       **********************************
CC	SEQRES LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	ATOM   LATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIA
CC	       **************************************************
CC	SEQRES MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	ATOM   MRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFS
CC	       **************************************************
CC	SEQRES KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	ATOM   KKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKPCKE
CC	       **************************************************
CC	SEQRES TQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGAHHHH
CC	ATOM   TQIPLKLSLGGLLQPEKPVVLKVESR-----------
CC	       **************************           
SQ	SEQUENCE	487 AA;      MW;         CN;
	MAYLYGTHSH GLFKKLGIPG PTPLPFLGNI LSYHKGFCMF DMECHKKYGK VWGFYDGQQP
	VLAITDPDMI KTVLVKECYS VFTNRRPFGP VGFMKSAISI AEDEEWKRLR SLLSPTFTSG
	KLKEMVPIIA QYGDVLVRNL RREAETGKPV TLKDVFGAYS MDVITSTSFG VNIDSLNNPQ
	DPFVENTKKL LRFDFLDPFF LSITVFPFLI PILEVLNICV FPREVTNFLR KSVKRMKESR
	LEDTQKHRVD FLQLMIDSQN SKETESHKAL SDLELVAQSI IFIFAGYETT SSVLSFIMYE
	LATHPDVQQK LQEEIDAVLP NKAPPTYDTV LQMEYLDMVV NETLRLFPIA MRLERVCKKD
	VEINGMFIPK GVVVMIPSYA LHRDPKYWTE PEKFLPERFS KKNKDNIDPY IYTPFGSGPR
	NCIGMRFALM NMKLALIRVL QNFSFKPCKE TQIPLKLSLG GLLQPEKPVV LKVESRDGTV
	SGAHHHH
//