ID	3TJCA	STANDARD;	PRT;	298	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TJC
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.265
FT	#SUB	111	 945 	LYS	A	275	1109 	ASN	B	Protein	A	2
FT	#SUB	111	 945 	LYS	A	277	1111 	ASN	B	Protein	B	2
FT	#SUB	112	 946 	GLU	A	277	1111 	ASN	B	Protein	B	3
FT	#SUB	114	 948 	ILE	A	277	1111 	ASN	B	Protein	B	4
FT	#SUB	115	 949 	ASP	A	277	1111 	ASN	B	Protein	A	3
FT	#SUB	116	 950 	HIS	A	277	1111 	ASN	B	Protein	S	3
FT	#SUB	214	1048 	PHE	A	278	1112 	GLN	B	Protein	B	2
FT	#SUB	215	1049 	THR	A	278	1112 	GLN	B	Protein	B	1
FT	#SUB	216	1050 	TYR	A	275	1109 	ASN	B	Protein	S	3
FT	#SUB	216	1050 	TYR	A	277	1111 	ASN	B	Protein	S	1
FT	#SUB	216	1050 	TYR	A	278	1112 	GLN	B	Protein	S	5
FT	#SUB	256	1090 	ARG	A	270	1104 	GLU	B	Protein	S	9
FT	#SUB	256	1090 	ARG	A	288	1122 	ARG	B	Protein	S	4
FT	#SUB	258	1092 	ASP	A	273	1107 	ASN	B	Protein	S	1
FT	#SUB	258	1092 	ASP	A	278	1112 	GLN	B	Protein	A	8
FT	#SUB	259	1093 	GLY	A	270	1104 	GLU	B	Protein	B	2
FT	#SUB	259	1093 	GLY	A	278	1112 	GLN	B	Protein	B	3
FT	#SUB	261	1095 	PRO	A	284	1118 	ASP	B	Protein	A	3
FT	#SUB	263	1097 	GLU	A	283	1117 	ARG	B	Protein	S	1
FT	#SUB	296	1130 	MET	A	283	1117 	ARG	B	Protein	S	1
FT	#HET	21	 855 	LEU	A	1	1 	0TP	A	S	5
FT	#HET	22	 856 	GLY	A	1	1 	0TP	A	B	2
FT	#HET	23	 857 	LYS	A	1	1 	0TP	A	B	1
FT	#HET	24	 858 	GLY	A	1	1 	0TP	A	B	4
FT	#HET	29	 863 	VAL	A	1	1 	0TP	A	S	3
FT	#HET	46	 880 	ALA	A	1	1 	0TP	A	S	2
FT	#HET	96	 930 	GLU	A	1	1 	0TP	A	B	3
FT	#HET	97	 931 	TYR	A	1	1 	0TP	A	A	10
FT	#HET	98	 932 	LEU	A	1	1 	0TP	A	A	15
FT	#HET	99	 933 	PRO	A	1	1 	0TP	A	B	2
FT	#HET	101	 935 	GLY	A	1	1 	0TP	A	B	6
FT	#HET	146	 980 	ARG	A	1	1 	0TP	A	S	1
FT	#HET	147	 981 	ASN	A	1	1 	0TP	A	S	3
FT	#HET	149	 983 	LEU	A	1	1 	0TP	A	S	9
FT	#HET	160	 994 	ASP	A	1	1 	0TP	A	S	4
FT	DISORDER	1	8
FT	DISORDER	86	89
CC	SEQUENCE	286 AA (ATOM);
CC	QFEERHLKFL QQLGKGNFGS VEMCRYDPLQ DNTGEVVAVK KLQHSTEEHL RDFEREIEIL
CC	KSLQHDNIVK YKGVCYSNLK LIMEYLPYGS LRDYLQKHKE RIDHIKLLQY TSQICKGMEY
CC	LGTKRYIHRD LATRNILVEN ENRVKIGDFG LTKVLPQDKE YYKVKEPGES PIFWYAPESL
CC	TESKFSVASD VWSFGVVLYE LFTYIEKSKS PPAEFMRMIG NDKQGQMIVF HLIELLKNNG
CC	RLPRPDGCPD EIYMIMTECW NNNVNQRPSF RDLALRVDQI RDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL
CC	ATOM   --------QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL
CC	               ******************************************
CC	SEQRES QHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPY
CC	ATOM   QHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYS----NLKLIMEYLPY
CC	       ***********************************    ***********
CC	SEQRES GSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILV
CC	ATOM   GSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILV
CC	       **************************************************
CC	SEQRES ENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVA
CC	ATOM   ENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVA
CC	       **************************************************
CC	SEQRES SDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKN
CC	ATOM   SDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKN
CC	       **************************************************
CC	SEQRES NGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
CC	ATOM   NGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
CC	       ************************************************
SQ	SEQUENCE	298 AA;      MW;         CN;
	GSEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
//
ID	3TJCB	STANDARD;	PRT;	298	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TJC
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.265
FT	#SUB	270	1104 	GLU	B	256	1090 	ARG	A	Protein	S	9
FT	#SUB	270	1104 	GLU	B	259	1093 	GLY	A	Protein	S	2
FT	#SUB	273	1107 	ASN	B	258	1092 	ASP	A	Protein	S	1
FT	#SUB	275	1109 	ASN	B	111	 945 	LYS	A	Protein	S	2
FT	#SUB	275	1109 	ASN	B	216	1050 	TYR	A	Protein	S	3
FT	#SUB	277	1111 	ASN	B	111	 945 	LYS	A	Protein	S	2
FT	#SUB	277	1111 	ASN	B	112	 946 	GLU	A	Protein	S	3
FT	#SUB	277	1111 	ASN	B	114	 948 	ILE	A	Protein	S	4
FT	#SUB	277	1111 	ASN	B	115	 949 	ASP	A	Protein	S	3
FT	#SUB	277	1111 	ASN	B	116	 950 	HIS	A	Protein	B	3
FT	#SUB	277	1111 	ASN	B	216	1050 	TYR	A	Protein	S	1
FT	#SUB	278	1112 	GLN	B	214	1048 	PHE	A	Protein	S	2
FT	#SUB	278	1112 	GLN	B	215	1049 	THR	A	Protein	S	1
FT	#SUB	278	1112 	GLN	B	216	1050 	TYR	A	Protein	S	5
FT	#SUB	278	1112 	GLN	B	258	1092 	ASP	A	Protein	A	8
FT	#SUB	278	1112 	GLN	B	259	1093 	GLY	A	Protein	B	3
FT	#SUB	283	1117 	ARG	B	263	1097 	GLU	A	Protein	S	1
FT	#SUB	283	1117 	ARG	B	296	1130 	MET	A	Protein	S	1
FT	#SUB	284	1118 	ASP	B	261	1095 	PRO	A	Protein	S	3
FT	#SUB	288	1122 	ARG	B	256	1090 	ARG	A	Protein	S	4
FT	#HET	21	 855 	LEU	B	2	1 	0TP	B	A	10
FT	#HET	22	 856 	GLY	B	2	1 	0TP	B	B	1
FT	#HET	23	 857 	LYS	B	2	1 	0TP	B	B	1
FT	#HET	24	 858 	GLY	B	2	1 	0TP	B	B	5
FT	#HET	29	 863 	VAL	B	2	1 	0TP	B	S	5
FT	#HET	46	 880 	ALA	B	2	1 	0TP	B	S	2
FT	#HET	96	 930 	GLU	B	2	1 	0TP	B	B	1
FT	#HET	97	 931 	TYR	B	2	1 	0TP	B	A	6
FT	#HET	98	 932 	LEU	B	2	1 	0TP	B	A	16
FT	#HET	99	 933 	PRO	B	2	1 	0TP	B	B	2
FT	#HET	101	 935 	GLY	B	2	1 	0TP	B	B	8
FT	#HET	147	 981 	ASN	B	2	1 	0TP	B	S	1
FT	#HET	149	 983 	LEU	B	2	1 	0TP	B	S	7
FT	DISORDER	1	5
FT	DISORDER	86	89
CC	SEQUENCE	289 AA (ATOM);
CC	DPTQFEERHL KFLQQLGKGN FGSVEMCRYD PLQDNTGEVV AVKKLQHSTE EHLRDFEREI
CC	EILKSLQHDN IVKYKGVCYS NLKLIMEYLP YGSLRDYLQK HKERIDHIKL LQYTSQICKG
CC	MEYLGTKRYI HRDLATRNIL VENENRVKIG DFGLTKVLPQ DKEYYKVKEP GESPIFWYAP
CC	ESLTESKFSV ASDVWSFGVV LYELFTYIEK SKSPPAEFMR MIGNDKQGQM IVFHLIELLK
CC	NNGRLPRPDG CPDEIYMIMT ECWNNNVNQR PSFRDLALRV DQIRDNMAG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GSEDRDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL
CC	ATOM   -----DPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKL
CC	            *********************************************
CC	SEQRES QHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPY
CC	ATOM   QHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYS----NLKLIMEYLPY
CC	       ***********************************    ***********
CC	SEQRES GSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILV
CC	ATOM   GSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILV
CC	       **************************************************
CC	SEQRES ENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVA
CC	ATOM   ENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVA
CC	       **************************************************
CC	SEQRES SDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKN
CC	ATOM   SDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKN
CC	       **************************************************
CC	SEQRES NGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
CC	ATOM   NGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG
CC	       ************************************************
SQ	SEQUENCE	298 AA;      MW;         CN;
	GSEDRDPTQF EERHLKFLQQ LGKGNFGSVE MCRYDPLQDN TGEVVAVKKL QHSTEEHLRD
	FEREIEILKS LQHDNIVKYK GVCYSAGRRN LKLIMEYLPY GSLRDYLQKH KERIDHIKLL
	QYTSQICKGM EYLGTKRYIH RDLATRNILV ENENRVKIGD FGLTKVLPQD KEYYKVKEPG
	ESPIFWYAPE SLTESKFSVA SDVWSFGVVL YELFTYIEKS KSPPAEFMRM IGNDKQGQMI
	VFHLIELLKN NGRLPRPDGC PDEIYMIMTE CWNNNVNQRP SFRDLALRVD QIRDNMAG
//