ID	3TIKA	STANDARD;	PRT;	454	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TIK
DE	sterol 14-alpha demethylase (CYP51)
OS	Trypanosoma brucei
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.050
CC	R-Factor	0.189
FT	#SUB	1	  28 	LYS	A	159	 186 	GLU	B	Protein	B	1
FT	#SUB	3	  30 	LYS	A	154	 181 	GLN	B	Protein	S	6
FT	#SUB	3	  30 	LYS	A	157	 184 	PHE	B	Protein	S	3
FT	#SUB	4	  31 	LEU	A	114	 141 	ASN	B	Protein	B	1
FT	#SUB	4	  31 	LEU	A	117	 144 	PRO	B	Protein	S	3
FT	#SUB	4	  31 	LEU	A	118	 145 	ALA	B	Protein	S	2
FT	#SUB	5	  32 	PRO	A	114	 141 	ASN	B	Protein	B	3
FT	#SUB	6	  33 	PRO	A	114	 141 	ASN	B	Protein	B	3
FT	#SUB	7	  34 	VAL	A	113	 140 	GLN	B	Protein	S	2
FT	#SUB	7	  34 	VAL	A	114	 141 	ASN	B	Protein	A	7
FT	#SUB	9	  36 	PRO	A	113	 140 	GLN	B	Protein	A	2
FT	#SUB	10	  37 	VAL	A	306	 333 	ASN	B	Protein	A	8
FT	#SUB	13	  40 	PRO	A	311	 338 	GLU	B	Protein	B	1
FT	#SUB	44	  71 	ASN	A	304	 331 	ASN	B	Protein	S	1
FT	#SUB	47	  74 	GLY	A	300	 327 	PRO	B	Protein	B	3
FT	#SUB	49	  76 	ARG	A	117	 144 	PRO	B	Protein	S	2
FT	#SUB	49	  76 	ARG	A	302	 329 	GLN	B	Protein	A	8
FT	#SUB	339	 366 	ASP	A	121	 148 	HIS	B	Protein	S	6
FT	#SUB	348	 375 	PRO	A	121	 148 	HIS	B	Protein	S	2
FT	#SUB	350	 377 	GLY	A	302	 329 	GLN	B	Protein	B	3
FT	#SUB	351	 378 	ASP	A	302	 329 	GLN	B	Protein	A	4
FT	#SUB	15	  42 	LEU	A	190	 217 	ILE	D	Protein	S	1
FT	#SUB	15	  42 	LEU	A	194	 221 	LEU	D	Protein	S	1
FT	#SUB	18	  45 	ILE	A	194	 221 	LEU	D	Protein	S	1
FT	#SUB	18	  45 	ILE	A	195	 222 	PRO	D	Protein	S	2
FT	#SUB	46	  73 	VAL	A	190	 217 	ILE	D	Protein	S	1
FT	#SUB	179	 206 	SER	A	179	 206 	SER	D	Protein	A	4
FT	#SUB	179	 206 	SER	A	198	 225 	GLN	D	Protein	B	1
FT	#SUB	179	 206 	SER	A	201	 228 	ARG	D	Protein	B	4
FT	#SUB	181	 208 	LEU	A	197	 224 	PRO	D	Protein	B	1
FT	#SUB	181	 208 	LEU	A	198	 225 	GLN	D	Protein	B	3
FT	#SUB	182	 209 	ILE	A	182	 209 	ILE	D	Protein	S	1
FT	#SUB	182	 209 	ILE	A	196	 223 	LEU	D	Protein	S	1
FT	#SUB	182	 209 	ILE	A	198	 225 	GLN	D	Protein	S	1
FT	#SUB	183	 210 	PRO	A	197	 224 	PRO	D	Protein	S	3
FT	#SUB	188	 215 	LEU	A	194	 221 	LEU	D	Protein	S	1
FT	#SUB	190	 217 	ILE	A	14	  41 	ILE	D	Protein	S	2
FT	#SUB	190	 217 	ILE	A	15	  42 	LEU	D	Protein	S	2
FT	#SUB	190	 217 	ILE	A	46	  73 	VAL	D	Protein	S	1
FT	#SUB	191	 218 	LEU	A	191	 218 	LEU	D	Protein	S	1
FT	#SUB	194	 221 	LEU	A	15	  42 	LEU	D	Protein	S	1
FT	#SUB	194	 221 	LEU	A	188	 215 	LEU	D	Protein	S	1
FT	#SUB	195	 222 	PRO	A	19	  46 	ILE	D	Protein	S	2
FT	#SUB	196	 223 	LEU	A	184	 211 	ALA	D	Protein	S	1
FT	#SUB	197	 224 	PRO	A	183	 210 	PRO	D	Protein	S	1
FT	#SUB	198	 225 	GLN	A	179	 206 	SER	D	Protein	S	1
FT	#SUB	198	 225 	GLN	A	181	 208 	LEU	D	Protein	S	4
FT	#SUB	198	 225 	GLN	A	182	 209 	ILE	D	Protein	S	1
FT	#SUB	201	 228 	ARG	A	179	 206 	SER	D	Protein	S	6
FT	#SUB	433	 460 	MET	A	197	 224 	PRO	D	Protein	S	2
FT	#HET	76	 103 	TYR	A	1	482 	HEM	A	S	4
FT	#HET	76	 103 	TYR	A	2	490 	JKF	A	S	9
FT	#HET	78	 105 	PHE	A	2	490 	JKF	A	S	2
FT	#HET	79	 106 	MET	A	2	490 	JKF	A	S	5
FT	#HET	83	 110 	PHE	A	2	490 	JKF	A	S	2
FT	#HET	88	 115 	ALA	A	2	490 	JKF	A	S	1
FT	#HET	89	 116 	TYR	A	1	482 	HEM	A	S	5
FT	#HET	89	 116 	TYR	A	2	490 	JKF	A	S	3
FT	#HET	97	 124 	ARG	A	1	482 	HEM	A	S	4
FT	#HET	100	 127 	LEU	A	1	482 	HEM	A	S	4
FT	#HET	107	 134 	LEU	A	1	482 	HEM	A	S	2
FT	#HET	181	 208 	LEU	A	2	490 	JKF	A	S	1
FT	#HET	261	 288 	ALA	A	1	482 	HEM	A	A	4
FT	#HET	263	 290 	PHE	A	2	490 	JKF	A	S	4
FT	#HET	264	 291 	ALA	A	1	482 	HEM	A	S	7
FT	#HET	264	 291 	ALA	A	2	490 	JKF	A	A	18
FT	#HET	265	 292 	GLY	A	1	482 	HEM	A	B	3
FT	#HET	268	 295 	THR	A	1	482 	HEM	A	A	12
FT	#HET	268	 295 	THR	A	2	490 	JKF	A	S	1
FT	#HET	269	 296 	SER	A	1	482 	HEM	A	A	3
FT	#HET	272	 299 	THR	A	1	482 	HEM	A	S	1
FT	#HET	329	 356 	LEU	A	1	482 	HEM	A	S	2
FT	#HET	329	 356 	LEU	A	2	490 	JKF	A	S	5
FT	#HET	331	 358 	MET	A	2	490 	JKF	A	B	1
FT	#HET	332	 359 	LEU	A	1	482 	HEM	A	S	2
FT	#HET	334	 361 	ARG	A	1	482 	HEM	A	S	8
FT	#HET	387	 414 	GLY	A	1	482 	HEM	A	B	4
FT	#HET	388	 415 	PHE	A	1	482 	HEM	A	A	13
FT	#HET	389	 416 	GLY	A	1	482 	HEM	A	B	1
FT	#HET	392	 419 	VAL	A	1	482 	HEM	A	B	1
FT	#HET	393	 420 	HIS	A	1	482 	HEM	A	A	19
FT	#HET	394	 421 	LYS	A	1	482 	HEM	A	B	1
FT	#HET	395	 422 	CYS	A	1	482 	HEM	A	A	24
FT	#HET	396	 423 	ILE	A	1	482 	HEM	A	A	7
FT	#HET	397	 424 	GLY	A	1	482 	HEM	A	B	14
FT	#HET	433	 460 	MET	A	2	490 	JKF	A	S	5
FT	#HET	434	 461 	VAL	A	2	490 	JKF	A	S	3
FT	DISORDER	451	454
CC	SEQUENCE	450 AA (ATOM);
CC	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
CC	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
CC	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
CC	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
CC	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
CC	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
CC	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
CC	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	ATOM   KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	       **************************************************
CC	SEQRES TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	ATOM   TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	       **************************************************
CC	SEQRES NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	ATOM   NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	       **************************************************
CC	SEQRES TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	ATOM   TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	       **************************************************
CC	SEQRES RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	ATOM   RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	       **************************************************
CC	SEQRES LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	ATOM   LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	       **************************************************
CC	SEQRES AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	ATOM   AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	       **************************************************
CC	SEQRES DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	ATOM   DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	       **************************************************
CC	SEQRES GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	ATOM   GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	       **************************************************
CC	SEQRES AAAA
CC	ATOM   ----
CC	           
SQ	SEQUENCE	454 AA;      MW;         CN;
	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK AAAA
//
ID	3TIKB	STANDARD;	PRT;	454	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TIK
DE	sterol 14-alpha demethylase (CYP51)
OS	Trypanosoma brucei
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.050
CC	R-Factor	0.189
FT	#SUB	113	 140 	GLN	B	7	  34 	VAL	A	Protein	B	2
FT	#SUB	113	 140 	GLN	B	9	  36 	PRO	A	Protein	S	2
FT	#SUB	114	 141 	ASN	B	4	  31 	LEU	A	Protein	S	1
FT	#SUB	114	 141 	ASN	B	5	  32 	PRO	A	Protein	S	3
FT	#SUB	114	 141 	ASN	B	6	  33 	PRO	A	Protein	S	3
FT	#SUB	114	 141 	ASN	B	7	  34 	VAL	A	Protein	S	7
FT	#SUB	117	 144 	PRO	B	4	  31 	LEU	A	Protein	A	3
FT	#SUB	117	 144 	PRO	B	49	  76 	ARG	A	Protein	S	2
FT	#SUB	118	 145 	ALA	B	4	  31 	LEU	A	Protein	B	2
FT	#SUB	121	 148 	HIS	B	339	 366 	ASP	A	Protein	S	6
FT	#SUB	121	 148 	HIS	B	348	 375 	PRO	A	Protein	S	2
FT	#SUB	154	 181 	GLN	B	3	  30 	LYS	A	Protein	A	6
FT	#SUB	157	 184 	PHE	B	3	  30 	LYS	A	Protein	B	3
FT	#SUB	159	 186 	GLU	B	1	  28 	LYS	A	Protein	S	1
FT	#SUB	300	 327 	PRO	B	47	  74 	GLY	A	Protein	S	3
FT	#SUB	302	 329 	GLN	B	49	  76 	ARG	A	Protein	S	8
FT	#SUB	302	 329 	GLN	B	350	 377 	GLY	A	Protein	S	3
FT	#SUB	302	 329 	GLN	B	351	 378 	ASP	A	Protein	S	4
FT	#SUB	304	 331 	ASN	B	44	  71 	ASN	A	Protein	S	1
FT	#SUB	306	 333 	ASN	B	10	  37 	VAL	A	Protein	S	8
FT	#SUB	311	 338 	GLU	B	13	  40 	PRO	A	Protein	S	1
FT	#SUB	66	  93 	ARG	B	378	 405 	ASP	C	Protein	S	1
FT	#SUB	108	 135 	THR	B	298	 325 	GLU	C	Protein	B	2
FT	#SUB	109	 136 	ILE	B	297	 324 	GLU	C	Protein	S	2
FT	#SUB	109	 136 	ILE	B	298	 325 	GLU	C	Protein	A	8
FT	#SUB	309	 336 	MET	B	300	 327 	PRO	C	Protein	B	1
FT	#SUB	310	 337 	ASP	B	300	 327 	PRO	C	Protein	S	3
FT	#SUB	310	 337 	ASP	B	301	 328 	ALA	C	Protein	S	1
FT	#SUB	320	 347 	ARG	B	306	 333 	ASN	C	Protein	S	4
FT	#SUB	341	 368 	LYS	B	382	 409 	GLU	C	Protein	S	1
FT	#SUB	378	 405 	ASP	B	113	 140 	GLN	C	Protein	S	11
FT	#SUB	379	 406 	GLU	B	109	 136 	ILE	C	Protein	B	3
FT	#SUB	379	 406 	GLU	B	305	 332 	TYR	C	Protein	S	2
FT	#SUB	379	 406 	GLU	B	306	 333 	ASN	C	Protein	S	1
FT	#SUB	380	 407 	LYS	B	109	 136 	ILE	C	Protein	B	4
FT	#SUB	382	 409 	GLU	B	109	 136 	ILE	C	Protein	S	1
FT	#SUB	382	 409 	GLU	B	309	 336 	MET	C	Protein	S	1
FT	#SUB	382	 409 	GLU	B	399	 426 	LYS	C	Protein	S	3
FT	#SUB	398	 425 	GLN	B	311	 338 	GLU	C	Protein	S	1
FT	#SUB	399	 426 	LYS	B	298	 325 	GLU	C	Protein	S	3
FT	#SUB	399	 426 	LYS	B	311	 338 	GLU	C	Protein	S	1
FT	#HET	76	 103 	TYR	B	3	482 	HEM	B	S	5
FT	#HET	76	 103 	TYR	B	4	490 	JKF	B	S	10
FT	#HET	78	 105 	PHE	B	4	490 	JKF	B	S	2
FT	#HET	79	 106 	MET	B	4	490 	JKF	B	S	5
FT	#HET	83	 110 	PHE	B	4	490 	JKF	B	S	4
FT	#HET	88	 115 	ALA	B	4	490 	JKF	B	S	1
FT	#HET	89	 116 	TYR	B	3	482 	HEM	B	S	5
FT	#HET	89	 116 	TYR	B	4	490 	JKF	B	S	2
FT	#HET	97	 124 	ARG	B	3	482 	HEM	B	S	4
FT	#HET	100	 127 	LEU	B	3	482 	HEM	B	S	6
FT	#HET	107	 134 	LEU	B	3	482 	HEM	B	S	2
FT	#HET	181	 208 	LEU	B	4	490 	JKF	B	S	1
FT	#HET	261	 288 	ALA	B	3	482 	HEM	B	A	3
FT	#HET	263	 290 	PHE	B	4	490 	JKF	B	A	6
FT	#HET	264	 291 	ALA	B	3	482 	HEM	B	A	8
FT	#HET	264	 291 	ALA	B	4	490 	JKF	B	A	17
FT	#HET	265	 292 	GLY	B	3	482 	HEM	B	B	3
FT	#HET	268	 295 	THR	B	3	482 	HEM	B	A	12
FT	#HET	269	 296 	SER	B	3	482 	HEM	B	A	3
FT	#HET	272	 299 	THR	B	3	482 	HEM	B	S	1
FT	#HET	329	 356 	LEU	B	3	482 	HEM	B	S	3
FT	#HET	329	 356 	LEU	B	4	490 	JKF	B	S	8
FT	#HET	331	 358 	MET	B	4	490 	JKF	B	B	1
FT	#HET	332	 359 	LEU	B	3	482 	HEM	B	S	5
FT	#HET	334	 361 	ARG	B	3	482 	HEM	B	S	8
FT	#HET	387	 414 	GLY	B	3	482 	HEM	B	B	4
FT	#HET	388	 415 	PHE	B	3	482 	HEM	B	A	16
FT	#HET	389	 416 	GLY	B	3	482 	HEM	B	B	3
FT	#HET	392	 419 	VAL	B	3	482 	HEM	B	B	1
FT	#HET	393	 420 	HIS	B	3	482 	HEM	B	A	15
FT	#HET	394	 421 	LYS	B	3	482 	HEM	B	B	1
FT	#HET	395	 422 	CYS	B	3	482 	HEM	B	A	24
FT	#HET	396	 423 	ILE	B	3	482 	HEM	B	A	6
FT	#HET	397	 424 	GLY	B	3	482 	HEM	B	B	14
FT	#HET	433	 460 	MET	B	4	490 	JKF	B	S	6
FT	#HET	434	 461 	VAL	B	4	490 	JKF	B	S	3
FT	DISORDER	451	454
CC	SEQUENCE	450 AA (ATOM);
CC	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
CC	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
CC	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
CC	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
CC	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
CC	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
CC	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
CC	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	ATOM   KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	       **************************************************
CC	SEQRES TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	ATOM   TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	       **************************************************
CC	SEQRES NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	ATOM   NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	       **************************************************
CC	SEQRES TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	ATOM   TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	       **************************************************
CC	SEQRES RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	ATOM   RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	       **************************************************
CC	SEQRES LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	ATOM   LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	       **************************************************
CC	SEQRES AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	ATOM   AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	       **************************************************
CC	SEQRES DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	ATOM   DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	       **************************************************
CC	SEQRES GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	ATOM   GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	       **************************************************
CC	SEQRES AAAA
CC	ATOM   ----
CC	           
SQ	SEQUENCE	454 AA;      MW;         CN;
	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK AAAA
//
ID	3TIKC	STANDARD;	PRT;	454	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TIK
DE	sterol 14-alpha demethylase (CYP51)
OS	Trypanosoma brucei
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.050
CC	R-Factor	0.189
FT	#SUB	109	 136 	ILE	C	379	 406 	GLU	B	Protein	S	3
FT	#SUB	109	 136 	ILE	C	380	 407 	LYS	B	Protein	S	4
FT	#SUB	109	 136 	ILE	C	382	 409 	GLU	B	Protein	S	1
FT	#SUB	113	 140 	GLN	C	378	 405 	ASP	B	Protein	S	11
FT	#SUB	297	 324 	GLU	C	109	 136 	ILE	B	Protein	B	2
FT	#SUB	298	 325 	GLU	C	108	 135 	THR	B	Protein	S	2
FT	#SUB	298	 325 	GLU	C	109	 136 	ILE	B	Protein	A	8
FT	#SUB	298	 325 	GLU	C	399	 426 	LYS	B	Protein	A	3
FT	#SUB	300	 327 	PRO	C	309	 336 	MET	B	Protein	S	1
FT	#SUB	300	 327 	PRO	C	310	 337 	ASP	B	Protein	A	3
FT	#SUB	301	 328 	ALA	C	310	 337 	ASP	B	Protein	B	1
FT	#SUB	305	 332 	TYR	C	379	 406 	GLU	B	Protein	S	2
FT	#SUB	306	 333 	ASN	C	320	 347 	ARG	B	Protein	S	4
FT	#SUB	306	 333 	ASN	C	379	 406 	GLU	B	Protein	S	1
FT	#SUB	309	 336 	MET	C	382	 409 	GLU	B	Protein	S	1
FT	#SUB	311	 338 	GLU	C	398	 425 	GLN	B	Protein	S	1
FT	#SUB	311	 338 	GLU	C	399	 426 	LYS	B	Protein	S	1
FT	#SUB	378	 405 	ASP	C	66	  93 	ARG	B	Protein	S	1
FT	#SUB	382	 409 	GLU	C	341	 368 	LYS	B	Protein	S	1
FT	#SUB	399	 426 	LYS	C	382	 409 	GLU	B	Protein	S	3
FT	#SUB	226	 253 	ASN	C	341	 368 	LYS	D	Protein	A	3
FT	#SUB	228	 255 	ASP	C	339	 366 	ASP	D	Protein	S	2
FT	#HET	76	 103 	TYR	C	5	482 	HEM	C	S	5
FT	#HET	76	 103 	TYR	C	6	490 	JKF	C	S	7
FT	#HET	78	 105 	PHE	C	6	490 	JKF	C	S	2
FT	#HET	83	 110 	PHE	C	6	490 	JKF	C	S	3
FT	#HET	88	 115 	ALA	C	6	490 	JKF	C	S	1
FT	#HET	89	 116 	TYR	C	5	482 	HEM	C	S	6
FT	#HET	89	 116 	TYR	C	6	490 	JKF	C	S	2
FT	#HET	97	 124 	ARG	C	5	482 	HEM	C	S	3
FT	#HET	100	 127 	LEU	C	5	482 	HEM	C	S	4
FT	#HET	107	 134 	LEU	C	5	482 	HEM	C	S	1
FT	#HET	181	 208 	LEU	C	6	490 	JKF	C	S	1
FT	#HET	261	 288 	ALA	C	5	482 	HEM	C	A	4
FT	#HET	263	 290 	PHE	C	6	490 	JKF	C	S	4
FT	#HET	264	 291 	ALA	C	5	482 	HEM	C	S	7
FT	#HET	264	 291 	ALA	C	6	490 	JKF	C	A	16
FT	#HET	265	 292 	GLY	C	5	482 	HEM	C	B	4
FT	#HET	268	 295 	THR	C	5	482 	HEM	C	A	14
FT	#HET	269	 296 	SER	C	5	482 	HEM	C	A	2
FT	#HET	272	 299 	THR	C	5	482 	HEM	C	S	1
FT	#HET	328	 355 	PRO	C	5	482 	HEM	C	S	1
FT	#HET	329	 356 	LEU	C	5	482 	HEM	C	S	4
FT	#HET	329	 356 	LEU	C	6	490 	JKF	C	S	4
FT	#HET	331	 358 	MET	C	6	490 	JKF	C	B	1
FT	#HET	332	 359 	LEU	C	5	482 	HEM	C	S	5
FT	#HET	334	 361 	ARG	C	5	482 	HEM	C	S	8
FT	#HET	387	 414 	GLY	C	5	482 	HEM	C	B	3
FT	#HET	388	 415 	PHE	C	5	482 	HEM	C	A	14
FT	#HET	389	 416 	GLY	C	5	482 	HEM	C	B	2
FT	#HET	392	 419 	VAL	C	5	482 	HEM	C	B	1
FT	#HET	393	 420 	HIS	C	5	482 	HEM	C	A	14
FT	#HET	394	 421 	LYS	C	5	482 	HEM	C	B	1
FT	#HET	395	 422 	CYS	C	5	482 	HEM	C	A	28
FT	#HET	396	 423 	ILE	C	5	482 	HEM	C	A	5
FT	#HET	397	 424 	GLY	C	5	482 	HEM	C	B	14
FT	#HET	433	 460 	MET	C	6	490 	JKF	C	S	6
FT	#HET	434	 461 	VAL	C	6	490 	JKF	C	S	3
FT	DISORDER	451	454
CC	SEQUENCE	450 AA (ATOM);
CC	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
CC	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
CC	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
CC	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
CC	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
CC	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
CC	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
CC	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	ATOM   KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	       **************************************************
CC	SEQRES TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	ATOM   TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	       **************************************************
CC	SEQRES NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	ATOM   NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	       **************************************************
CC	SEQRES TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	ATOM   TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	       **************************************************
CC	SEQRES RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	ATOM   RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	       **************************************************
CC	SEQRES LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	ATOM   LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	       **************************************************
CC	SEQRES AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	ATOM   AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	       **************************************************
CC	SEQRES DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	ATOM   DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	       **************************************************
CC	SEQRES GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	ATOM   GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	       **************************************************
CC	SEQRES AAAA
CC	ATOM   ----
CC	           
SQ	SEQUENCE	454 AA;      MW;         CN;
	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK AAAA
//
ID	3TIKD	STANDARD;	PRT;	454	AA.
DT	CONVERTED FROM PDB (SEQRES) 3TIK
DE	sterol 14-alpha demethylase (CYP51)
OS	Trypanosoma brucei
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.050
CC	R-Factor	0.189
FT	#SUB	14	  41 	ILE	D	190	 217 	ILE	A	Protein	A	2
FT	#SUB	15	  42 	LEU	D	190	 217 	ILE	A	Protein	S	2
FT	#SUB	15	  42 	LEU	D	194	 221 	LEU	A	Protein	S	1
FT	#SUB	19	  46 	ILE	D	195	 222 	PRO	A	Protein	S	2
FT	#SUB	46	  73 	VAL	D	190	 217 	ILE	A	Protein	S	1
FT	#SUB	179	 206 	SER	D	179	 206 	SER	A	Protein	A	4
FT	#SUB	179	 206 	SER	D	198	 225 	GLN	A	Protein	B	1
FT	#SUB	179	 206 	SER	D	201	 228 	ARG	A	Protein	A	6
FT	#SUB	181	 208 	LEU	D	198	 225 	GLN	A	Protein	B	4
FT	#SUB	182	 209 	ILE	D	182	 209 	ILE	A	Protein	S	1
FT	#SUB	182	 209 	ILE	D	198	 225 	GLN	A	Protein	S	1
FT	#SUB	183	 210 	PRO	D	197	 224 	PRO	A	Protein	S	1
FT	#SUB	184	 211 	ALA	D	196	 223 	LEU	A	Protein	S	1
FT	#SUB	188	 215 	LEU	D	194	 221 	LEU	A	Protein	S	1
FT	#SUB	190	 217 	ILE	D	15	  42 	LEU	A	Protein	S	1
FT	#SUB	190	 217 	ILE	D	46	  73 	VAL	A	Protein	S	1
FT	#SUB	191	 218 	LEU	D	191	 218 	LEU	A	Protein	S	1
FT	#SUB	194	 221 	LEU	D	15	  42 	LEU	A	Protein	S	1
FT	#SUB	194	 221 	LEU	D	18	  45 	ILE	A	Protein	S	1
FT	#SUB	194	 221 	LEU	D	188	 215 	LEU	A	Protein	S	1
FT	#SUB	195	 222 	PRO	D	18	  45 	ILE	A	Protein	S	2
FT	#SUB	196	 223 	LEU	D	182	 209 	ILE	A	Protein	S	1
FT	#SUB	197	 224 	PRO	D	181	 208 	LEU	A	Protein	S	1
FT	#SUB	197	 224 	PRO	D	183	 210 	PRO	A	Protein	S	3
FT	#SUB	197	 224 	PRO	D	433	 460 	MET	A	Protein	S	2
FT	#SUB	198	 225 	GLN	D	179	 206 	SER	A	Protein	S	1
FT	#SUB	198	 225 	GLN	D	181	 208 	LEU	A	Protein	S	3
FT	#SUB	198	 225 	GLN	D	182	 209 	ILE	A	Protein	S	1
FT	#SUB	201	 228 	ARG	D	179	 206 	SER	A	Protein	S	4
FT	#SUB	339	 366 	ASP	D	228	 255 	ASP	C	Protein	S	2
FT	#SUB	341	 368 	LYS	D	226	 253 	ASN	C	Protein	S	3
FT	#HET	76	 103 	TYR	D	7	482 	HEM	D	S	5
FT	#HET	76	 103 	TYR	D	8	490 	JKF	D	S	9
FT	#HET	78	 105 	PHE	D	8	490 	JKF	D	S	2
FT	#HET	79	 106 	MET	D	8	490 	JKF	D	S	3
FT	#HET	83	 110 	PHE	D	8	490 	JKF	D	S	3
FT	#HET	88	 115 	ALA	D	8	490 	JKF	D	S	1
FT	#HET	89	 116 	TYR	D	7	482 	HEM	D	S	6
FT	#HET	89	 116 	TYR	D	8	490 	JKF	D	S	4
FT	#HET	97	 124 	ARG	D	7	482 	HEM	D	S	4
FT	#HET	100	 127 	LEU	D	7	482 	HEM	D	S	3
FT	#HET	107	 134 	LEU	D	7	482 	HEM	D	S	1
FT	#HET	181	 208 	LEU	D	8	490 	JKF	D	S	2
FT	#HET	261	 288 	ALA	D	7	482 	HEM	D	A	2
FT	#HET	263	 290 	PHE	D	8	490 	JKF	D	S	2
FT	#HET	264	 291 	ALA	D	7	482 	HEM	D	S	6
FT	#HET	264	 291 	ALA	D	8	490 	JKF	D	A	18
FT	#HET	265	 292 	GLY	D	7	482 	HEM	D	B	2
FT	#HET	268	 295 	THR	D	7	482 	HEM	D	A	13
FT	#HET	268	 295 	THR	D	8	490 	JKF	D	S	1
FT	#HET	269	 296 	SER	D	7	482 	HEM	D	A	2
FT	#HET	272	 299 	THR	D	7	482 	HEM	D	S	1
FT	#HET	329	 356 	LEU	D	7	482 	HEM	D	S	4
FT	#HET	329	 356 	LEU	D	8	490 	JKF	D	S	6
FT	#HET	331	 358 	MET	D	8	490 	JKF	D	B	1
FT	#HET	332	 359 	LEU	D	7	482 	HEM	D	S	3
FT	#HET	332	 359 	LEU	D	8	490 	JKF	D	S	1
FT	#HET	334	 361 	ARG	D	7	482 	HEM	D	S	8
FT	#HET	387	 414 	GLY	D	7	482 	HEM	D	B	4
FT	#HET	388	 415 	PHE	D	7	482 	HEM	D	A	16
FT	#HET	389	 416 	GLY	D	7	482 	HEM	D	B	3
FT	#HET	392	 419 	VAL	D	7	482 	HEM	D	B	1
FT	#HET	393	 420 	HIS	D	7	482 	HEM	D	A	17
FT	#HET	394	 421 	LYS	D	7	482 	HEM	D	B	1
FT	#HET	395	 422 	CYS	D	7	482 	HEM	D	A	25
FT	#HET	396	 423 	ILE	D	7	482 	HEM	D	A	7
FT	#HET	397	 424 	GLY	D	7	482 	HEM	D	B	12
FT	#HET	433	 460 	MET	D	8	490 	JKF	D	S	5
FT	#HET	434	 461 	VAL	D	8	490 	JKF	D	S	3
FT	DISORDER	451	454
CC	SEQUENCE	450 AA (ATOM);
CC	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
CC	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
CC	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
CC	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
CC	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
CC	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
CC	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
CC	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	ATOM   KGKLPPVYPVTVPILGHIIQFGKSPLGFMQECKRQLKSGIFTINIVGKRV
CC	       **************************************************
CC	SEQRES TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	ATOM   TIVGDPHEHSRFFLPRNEVLSPREVYSFMVPVFGEGVAYAAPYPRMREQL
CC	       **************************************************
CC	SEQRES NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	ATOM   NFLAEELTIAKFQNFVPAIQHEVRKFMAANWDKDEGEINLLEDCSTMIIN
CC	       **************************************************
CC	SEQRES TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	ATOM   TACQCLFGEDLRKRLDARRFAQLLAKMESSLIPAAVFLPILLKLPLPQSA
CC	       **************************************************
CC	SEQRES RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	ATOM   RCHEARTELQKILSEIIIARKEEEVNKDSSTSDLLSGLLSAVYRDGTPMS
CC	       **************************************************
CC	SEQRES LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	ATOM   LHEVCGMIVAAMFAGQHTSSITTTWSMLHLMHPANVKHLEALRKEIEEFP
CC	       **************************************************
CC	SEQRES AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	ATOM   AQLNYNNVMDEMPFAERCARESIRRDPPLLMLMRKVMADVKVGSYVVPKG
CC	       **************************************************
CC	SEQRES DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	ATOM   DIIACSPLLSHHDEEAFPEPRRWDPERDEKVEGAFIGFGAGVHKCIGQKF
CC	       **************************************************
CC	SEQRES GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	ATOM   GLLQVKTILATAFRSYDFQLLRDEVPDPDYHTMVVGPTASQCRVKYIRRK
CC	       **************************************************
CC	SEQRES AAAA
CC	ATOM   ----
CC	           
SQ	SEQUENCE	454 AA;      MW;         CN;
	KGKLPPVYPV TVPILGHIIQ FGKSPLGFMQ ECKRQLKSGI FTINIVGKRV TIVGDPHEHS
	RFFLPRNEVL SPREVYSFMV PVFGEGVAYA APYPRMREQL NFLAEELTIA KFQNFVPAIQ
	HEVRKFMAAN WDKDEGEINL LEDCSTMIIN TACQCLFGED LRKRLDARRF AQLLAKMESS
	LIPAAVFLPI LLKLPLPQSA RCHEARTELQ KILSEIIIAR KEEEVNKDSS TSDLLSGLLS
	AVYRDGTPMS LHEVCGMIVA AMFAGQHTSS ITTTWSMLHL MHPANVKHLE ALRKEIEEFP
	AQLNYNNVMD EMPFAERCAR ESIRRDPPLL MLMRKVMADV KVGSYVVPKG DIIACSPLLS
	HHDEEAFPEP RRWDPERDEK VEGAFIGFGA GVHKCIGQKF GLLQVKTILA TAFRSYDFQL
	LRDEVPDPDY HTMVVGPTAS QCRVKYIRRK AAAA
//