ID	3SFFA	STANDARD;	PRT;	378	AA.
DT	CONVERTED FROM PDB (SEQRES) 3SFF
DE	Histone deacetylase 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.179
FT	#HET	35	  34 	ILE	A	1	378 	0DI	A	S	2
FT	#HET	141	 140 	GLY	A	1	378 	0DI	A	B	3
FT	#HET	142	 141 	TRP	A	1	378 	0DI	A	A	18
FT	#HET	143	 142 	HIS	A	1	378 	0DI	A	S	5
FT	#HET	144	 143 	HIS	A	1	378 	0DI	A	S	6
FT	#HET	152	 151 	GLY	A	1	378 	0DI	A	B	7
FT	#HET	153	 152 	PHE	A	1	378 	0DI	A	A	5
FT	#HET	154	 153 	CYS	A	1	378 	0DI	A	S	3
FT	#HET	177	 176 	ASP	A	2	401 	K	A	A	5
FT	#HET	179	 178 	ASP	A	1	378 	0DI	A	S	3
FT	#HET	179	 178 	ASP	A	2	401 	K	A	B	4
FT	#HET	179	 178 	ASP	A	4	403 	ZN	A	S	3
FT	#HET	181	 180 	HIS	A	1	378 	0DI	A	S	12
FT	#HET	181	 180 	HIS	A	2	401 	K	A	B	2
FT	#HET	181	 180 	HIS	A	4	403 	ZN	A	A	5
FT	#HET	190	 189 	PHE	A	3	402 	K	A	B	2
FT	#HET	193	 192 	THR	A	3	402 	K	A	B	2
FT	#HET	196	 195 	VAL	A	3	402 	K	A	B	2
FT	#HET	200	 199 	SER	A	2	401 	K	A	S	1
FT	#HET	201	 200 	LEU	A	2	401 	K	A	B	3
FT	#HET	202	 201 	HIS	A	2	401 	K	A	S	1
FT	#HET	209	 208 	PHE	A	1	378 	0DI	A	S	12
FT	#HET	226	 225 	TYR	A	3	402 	K	A	A	3
FT	#HET	268	 267 	ASP	A	1	378 	0DI	A	S	3
FT	#HET	268	 267 	ASP	A	4	403 	ZN	A	S	3
FT	#HET	275	 274 	MET	A	1	378 	0DI	A	S	1
FT	#HET	304	 303 	GLY	A	1	378 	0DI	A	B	8
FT	#HET	305	 304 	GLY	A	1	378 	0DI	A	B	8
FT	#HET	307	 306 	TYR	A	1	378 	0DI	A	S	3
FT	DISORDER	1	14
FT	DISORDER	85	107
CC	SEQUENCE	341 AA (ATOM);
CC	LVPVYIYSPE YVSMCDSLAK IPKRASMVHS LIEAYALHKQ MRIVKPKVAS MEEMATFHTD
CC	AYLQHLQKVS GIFDYAAAIG GATITAAQCL IDGMCKVAIN WSGGWHHAKK DEASGFCYLN
CC	DAVLGILRLR RKFERILYVD LDLHHGDGVE DAFSFTSKVM TVSLHKFSPG FFPGTGDVSD
CC	VGLGKGRYYS VNVPIQDGIQ DEKYYQICES VLKEVYQAFN PKAVVLQLGA DTIAGDPMCS
CC	FNMTPVGIGK CLKYILQWQL ATLILGGGGY NLANTARCWT YLTGVILGKT LSSEIPDHEF
CC	FTAYGPDYVL EITPSCRPDR NEPHRIQQIL NYIKGNLKHV V
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYA
CC	ATOM   --------------LVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYA
CC	                     ************************************
CC	SEQRES LHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLG
CC	ATOM   LHKQMRIVKPKVASMEEMATFHTDAYLQHLQKVS----------------
CC	       **********************************                
CC	SEQRES YDCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEA
CC	ATOM   -------GIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEA
CC	              *******************************************
CC	SEQRES SGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVS
CC	ATOM   SGFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVS
CC	       **************************************************
CC	SEQRES LHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLK
CC	ATOM   LHKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLK
CC	       **************************************************
CC	SEQRES EVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATL
CC	ATOM   EVYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATL
CC	       **************************************************
CC	SEQRES ILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEIT
CC	ATOM   ILGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEIT
CC	       **************************************************
CC	SEQRES PSCRPDRNEPHRIQQILNYIKGNLKHVV
CC	ATOM   PSCRPDRNEPHRIQQILNYIKGNLKHVV
CC	       ****************************
SQ	SEQUENCE	378 AA;      MW;         CN;
	SMEEPEEPAD SGQSLVPVYI YSPEYVSMCD SLAKIPKRAS MVHSLIEAYA LHKQMRIVKP
	KVASMEEMAT FHTDAYLQHL QKVSQEGDDD HPDSIEYGLG YDCPATEGIF DYAAAIGGAT
	ITAAQCLIDG MCKVAINWSG GWHHAKKDEA SGFCYLNDAV LGILRLRRKF ERILYVDLDL
	HHGDGVEDAF SFTSKVMTVS LHKFSPGFFP GTGDVSDVGL GKGRYYSVNV PIQDGIQDEK
	YYQICESVLK EVYQAFNPKA VVLQLGADTI AGDPMCSFNM TPVGIGKCLK YILQWQLATL
	ILGGGGYNLA NTARCWTYLT GVILGKTLSS EIPDHEFFTA YGPDYVLEIT PSCRPDRNEP
	HRIQQILNYI KGNLKHVV
//