ID	3QU8A	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	74	  93 	GLU	A	266	 285 	HIS	B	Protein	S	2
FT	#SUB	100	 119 	ASN	A	260	 279 	ALA	B	Protein	S	4
FT	#SUB	261	 280 	HIS	A	261	 280 	HIS	B	Protein	S	3
FT	#SUB	353	 372 	THR	A	267	 286 	GLN	B	Protein	B	1
FT	#SUB	354	 373 	GLN	A	266	 285 	HIS	B	Protein	S	4
FT	#SUB	354	 373 	GLN	A	267	 286 	GLN	B	Protein	A	7
FT	#SUB	354	 373 	GLN	A	270	 289 	ASN	B	Protein	S	1
FT	#SUB	355	 374 	HIS	A	88	 107 	PHE	B	Protein	S	7
FT	#SUB	355	 374 	HIS	A	220	 239 	GLN	B	Protein	S	7
FT	#SUB	355	 374 	HIS	A	223	 242 	ASN	B	Protein	S	1
FT	#SUB	355	 374 	HIS	A	267	 286 	GLN	B	Protein	A	6
FT	#SUB	357	 376 	SER	A	224	 243 	ALA	B	Protein	S	2
FT	#SUB	362	 381 	ILE	A	220	 239 	GLN	B	Protein	S	6
FT	#SUB	364	 383 	PRO	A	216	 235 	TYR	B	Protein	S	2
FT	#SUB	365	 384 	LYS	A	92	 111 	TYR	B	Protein	S	4
FT	#SUB	365	 384 	LYS	A	267	 286 	GLN	B	Protein	S	1
FT	#SUB	18	  37 	LEU	A	209	 228 	PRO	C	Protein	S	1
FT	#SUB	19	  38 	PRO	A	208	 227 	PHE	C	Protein	B	1
FT	#SUB	20	  39 	LEU	A	204	 223 	PHE	C	Protein	S	1
FT	#SUB	21	  40 	LEU	A	204	 223 	PHE	C	Protein	S	1
FT	#SUB	21	  40 	LEU	A	208	 227 	PHE	C	Protein	S	6
FT	#SUB	25	  44 	LEU	A	209	 228 	PRO	C	Protein	S	1
FT	#SUB	204	 223 	PHE	A	20	  39 	LEU	C	Protein	S	2
FT	#SUB	208	 227 	PHE	A	19	  38 	PRO	C	Protein	S	1
FT	#SUB	208	 227 	PHE	A	21	  40 	LEU	C	Protein	S	3
FT	#SUB	209	 228 	PRO	A	18	  37 	LEU	C	Protein	S	1
FT	#SUB	316	 335 	HIS	A	174	 193 	GLN	D	Protein	S	10
FT	#SUB	316	 335 	HIS	A	175	 194 	GLU	D	Protein	S	1
FT	#HET	16	  35 	ARG	A	6	602 	CM5	B	S	2
FT	#HET	18	  37 	LEU	A	10	603 	CM5	C	S	2
FT	#HET	19	  38 	PRO	A	6	602 	CM5	B	S	1
FT	#HET	19	  38 	PRO	A	10	603 	CM5	C	S	1
FT	#HET	20	  39 	LEU	A	10	603 	CM5	C	S	1
FT	#HET	79	  98 	ARG	A	1	500 	HEM	A	S	5
FT	#HET	94	 113 	VAL	A	1	500 	HEM	A	A	3
FT	#HET	95	 114 	ILE	A	1	500 	HEM	A	A	7
FT	#HET	102	 121 	TRP	A	1	500 	HEM	A	S	7
FT	#HET	106	 125 	ARG	A	1	500 	HEM	A	S	6
FT	#HET	160	 179 	ILE	A	1	500 	HEM	A	S	2
FT	#HET	187	 206 	PHE	A	2	501 	3QU	A	S	1
FT	#HET	204	 223 	PHE	A	3	601 	CM5	A	S	4
FT	#HET	207	 226 	HIS	A	3	601 	CM5	A	B	7
FT	#HET	208	 227 	PHE	A	3	601 	CM5	A	A	6
FT	#HET	209	 228 	PRO	A	3	601 	CM5	A	A	6
FT	#HET	213	 232 	ARG	A	3	601 	CM5	A	S	5
FT	#HET	276	 295 	LEU	A	1	500 	HEM	A	A	3
FT	#HET	279	 298 	ALA	A	1	500 	HEM	A	A	5
FT	#HET	279	 298 	ALA	A	2	501 	3QU	A	A	8
FT	#HET	280	 299 	GLY	A	1	500 	HEM	A	B	7
FT	#HET	283	 302 	THR	A	1	500 	HEM	A	S	9
FT	#HET	283	 302 	THR	A	2	501 	3QU	A	S	3
FT	#HET	284	 303 	THR	A	1	500 	HEM	A	S	1
FT	#HET	287	 306 	THR	A	1	500 	HEM	A	S	1
FT	#HET	338	 357 	GLN	A	1	500 	HEM	A	S	1
FT	#HET	344	 363 	LEU	A	1	500 	HEM	A	S	3
FT	#HET	344	 363 	LEU	A	2	501 	3QU	A	S	2
FT	#HET	347	 366 	GLY	A	1	500 	HEM	A	B	1
FT	#HET	348	 367 	VAL	A	1	500 	HEM	A	A	6
FT	#HET	350	 369 	HIS	A	1	500 	HEM	A	S	8
FT	#HET	373	 392 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	409	 428 	PRO	A	1	500 	HEM	A	B	2
FT	#HET	410	 429 	PHE	A	1	500 	HEM	A	S	9
FT	#HET	411	 430 	SER	A	1	500 	HEM	A	S	6
FT	#HET	415	 434 	ARG	A	1	500 	HEM	A	A	11
FT	#HET	417	 436 	CYS	A	1	500 	HEM	A	A	21
FT	#HET	418	 437 	LEU	A	1	500 	HEM	A	S	6
FT	#HET	419	 438 	GLY	A	1	500 	HEM	A	B	3
FT	#HET	423	 442 	ALA	A	1	500 	HEM	A	S	1
FT	DISORDER	1	8
FT	DISORDER	119	121
FT	DISORDER	474	476
CC	SEQUENCE	462 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDFGM SVEERIQEEA
CC	QCLIEELRKS KGALMDPTFL FQSITANIIC SIVFGKRFHY QDQEFLKMLN LFYQTFSLIS
CC	SVFGQLFELF SGFLKHFPGA HRQVYKNLQE INAYIGHSVE KHRETLDPSA PRDLIDTYLL
CC	HMEKEKSNAH SEFSHQNLNL NTLSLFFAGT ETTSTTLRYG FLLMLKYPHV AERVYREIEQ
CC	VIGPHRPPEL HDRAKMPYTE AVIYEIQRFS DLLPMGVPHI VTQHTSFRGY IIPKDTEVFL
CC	ILSTALHDPH YFEKPDAFNP DHFLDANGAL KKTEAFIPFS LGKRICLGEG IARAELFLFF
CC	TTILQNFSMA SPVAPEDIDL TPQECGVGKI PPTYQIRFLP RH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRDFGM---SVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ******************   *****************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQIRFLPRH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//
ID	3QU8B	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	88	 107 	PHE	B	355	 374 	HIS	A	Protein	A	7
FT	#SUB	92	 111 	TYR	B	365	 384 	LYS	A	Protein	S	4
FT	#SUB	216	 235 	TYR	B	364	 383 	PRO	A	Protein	S	2
FT	#SUB	220	 239 	GLN	B	355	 374 	HIS	A	Protein	S	7
FT	#SUB	220	 239 	GLN	B	362	 381 	ILE	A	Protein	S	6
FT	#SUB	223	 242 	ASN	B	355	 374 	HIS	A	Protein	S	1
FT	#SUB	224	 243 	ALA	B	357	 376 	SER	A	Protein	A	2
FT	#SUB	260	 279 	ALA	B	100	 119 	ASN	A	Protein	B	4
FT	#SUB	261	 280 	HIS	B	261	 280 	HIS	A	Protein	S	3
FT	#SUB	266	 285 	HIS	B	74	  93 	GLU	A	Protein	S	2
FT	#SUB	266	 285 	HIS	B	354	 373 	GLN	A	Protein	S	4
FT	#SUB	267	 286 	GLN	B	353	 372 	THR	A	Protein	S	1
FT	#SUB	267	 286 	GLN	B	354	 373 	GLN	A	Protein	S	7
FT	#SUB	267	 286 	GLN	B	355	 374 	HIS	A	Protein	S	6
FT	#SUB	267	 286 	GLN	B	365	 384 	LYS	A	Protein	S	1
FT	#SUB	270	 289 	ASN	B	354	 373 	GLN	A	Protein	S	1
FT	#SUB	21	  40 	LEU	B	208	 227 	PHE	E	Protein	S	1
FT	#SUB	208	 227 	PHE	B	19	  38 	PRO	E	Protein	S	1
FT	#SUB	208	 227 	PHE	B	21	  40 	LEU	E	Protein	S	3
FT	#SUB	209	 228 	PRO	B	18	  37 	LEU	E	Protein	S	1
FT	#HET	18	  37 	LEU	B	17	605 	CM5	E	S	1
FT	#HET	20	  39 	LEU	B	7	608 	CM5	B	B	1
FT	#HET	21	  40 	LEU	B	7	608 	CM5	B	S	1
FT	#HET	53	  72 	PRO	B	7	608 	CM5	B	S	4
FT	#HET	79	  98 	ARG	B	4	500 	HEM	B	S	7
FT	#HET	85	 104 	VAL	B	5	501 	3QU	B	S	2
FT	#HET	89	 108 	PHE	B	5	501 	3QU	B	S	2
FT	#HET	94	 113 	VAL	B	4	500 	HEM	B	A	2
FT	#HET	95	 114 	ILE	B	4	500 	HEM	B	A	3
FT	#HET	96	 115 	PHE	B	5	501 	3QU	B	S	3
FT	#HET	102	 121 	TRP	B	4	500 	HEM	B	S	6
FT	#HET	106	 125 	ARG	B	4	500 	HEM	B	S	5
FT	#HET	113	 132 	MET	B	4	500 	HEM	B	S	1
FT	#HET	160	 179 	ILE	B	4	500 	HEM	B	S	1
FT	#HET	187	 206 	PHE	B	5	501 	3QU	B	S	3
FT	#HET	201	 220 	PHE	B	7	608 	CM5	B	S	9
FT	#HET	203	 222 	GLY	B	6	602 	CM5	B	B	1
FT	#HET	203	 222 	GLY	B	7	608 	CM5	B	B	3
FT	#HET	204	 223 	PHE	B	6	602 	CM5	B	A	6
FT	#HET	204	 223 	PHE	B	7	608 	CM5	B	A	9
FT	#HET	206	 225 	LYS	B	7	608 	CM5	B	S	1
FT	#HET	207	 226 	HIS	B	6	602 	CM5	B	A	21
FT	#HET	208	 227 	PHE	B	6	602 	CM5	B	A	7
FT	#HET	209	 228 	PRO	B	6	602 	CM5	B	S	3
FT	#HET	213	 232 	ARG	B	6	602 	CM5	B	S	7
FT	#HET	278	 297 	PHE	B	5	501 	3QU	B	S	7
FT	#HET	279	 298 	ALA	B	4	500 	HEM	B	A	6
FT	#HET	279	 298 	ALA	B	5	501 	3QU	B	A	10
FT	#HET	280	 299 	GLY	B	4	500 	HEM	B	B	7
FT	#HET	283	 302 	THR	B	4	500 	HEM	B	S	7
FT	#HET	283	 302 	THR	B	5	501 	3QU	B	S	8
FT	#HET	284	 303 	THR	B	4	500 	HEM	B	A	3
FT	#HET	287	 306 	THR	B	4	500 	HEM	B	S	1
FT	#HET	338	 357 	GLN	B	4	500 	HEM	B	S	1
FT	#HET	344	 363 	LEU	B	4	500 	HEM	B	S	4
FT	#HET	344	 363 	LEU	B	5	501 	3QU	B	S	2
FT	#HET	348	 367 	VAL	B	4	500 	HEM	B	S	2
FT	#HET	350	 369 	HIS	B	4	500 	HEM	B	S	5
FT	#HET	373	 392 	LEU	B	4	500 	HEM	B	S	1
FT	#HET	409	 428 	PRO	B	4	500 	HEM	B	B	3
FT	#HET	410	 429 	PHE	B	4	500 	HEM	B	A	14
FT	#HET	411	 430 	SER	B	4	500 	HEM	B	S	6
FT	#HET	415	 434 	ARG	B	4	500 	HEM	B	A	15
FT	#HET	417	 436 	CYS	B	4	500 	HEM	B	A	26
FT	#HET	418	 437 	LEU	B	4	500 	HEM	B	S	2
FT	#HET	419	 438 	GLY	B	4	500 	HEM	B	B	2
FT	#HET	423	 442 	ALA	B	4	500 	HEM	B	S	2
FT	DISORDER	1	8
FT	DISORDER	116	121
FT	DISORDER	474	476
CC	SEQUENCE	459 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDSVE ERIQEEAQCL
CC	IEELRKSKGA LMDPTFLFQS ITANIICSIV FGKRFHYQDQ EFLKMLNLFY QTFSLISSVF
CC	GQLFELFSGF LKHFPGAHRQ VYKNLQEINA YIGHSVEKHR ETLDPSAPRD LIDTYLLHME
CC	KEKSNAHSEF SHQNLNLNTL SLFFAGTETT STTLRYGFLL MLKYPHVAER VYREIEQVIG
CC	PHRPPELHDR AKMPYTEAVI YEIQRFSDLL PMGVPHIVTQ HTSFRGYIIP KDTEVFLILS
CC	TALHDPHYFE KPDAFNPDHF LDANGALKKT EAFIPFSLGK RICLGEGIAR AELFLFFTTI
CC	LQNFSMASPV APEDIDLTPQ ECGVGKIPPT YQIRFLPRH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRD------SVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ***************      *****************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQIRFLPRH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//
ID	3QU8C	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	18	  37 	LEU	C	209	 228 	PRO	A	Protein	S	1
FT	#SUB	19	  38 	PRO	C	208	 227 	PHE	A	Protein	B	1
FT	#SUB	20	  39 	LEU	C	204	 223 	PHE	A	Protein	S	2
FT	#SUB	21	  40 	LEU	C	208	 227 	PHE	A	Protein	S	3
FT	#SUB	204	 223 	PHE	C	20	  39 	LEU	A	Protein	S	1
FT	#SUB	204	 223 	PHE	C	21	  40 	LEU	A	Protein	S	1
FT	#SUB	208	 227 	PHE	C	19	  38 	PRO	A	Protein	S	1
FT	#SUB	208	 227 	PHE	C	21	  40 	LEU	A	Protein	S	6
FT	#SUB	209	 228 	PRO	C	18	  37 	LEU	A	Protein	S	1
FT	#SUB	209	 228 	PRO	C	25	  44 	LEU	A	Protein	B	1
FT	#SUB	88	 107 	PHE	C	355	 374 	HIS	E	Protein	A	9
FT	#SUB	92	 111 	TYR	C	365	 384 	LYS	E	Protein	S	4
FT	#SUB	216	 235 	TYR	C	364	 383 	PRO	E	Protein	S	2
FT	#SUB	217	 236 	LYS	C	10	  29 	LYS	E	Protein	S	2
FT	#SUB	220	 239 	GLN	C	355	 374 	HIS	E	Protein	S	9
FT	#SUB	220	 239 	GLN	C	362	 381 	ILE	E	Protein	S	4
FT	#SUB	223	 242 	ASN	C	355	 374 	HIS	E	Protein	S	1
FT	#SUB	224	 243 	ALA	C	357	 376 	SER	E	Protein	A	2
FT	#SUB	231	 250 	GLU	C	72	  91 	LYS	E	Protein	S	1
FT	#SUB	260	 279 	ALA	C	100	 119 	ASN	E	Protein	B	5
FT	#SUB	261	 280 	HIS	C	261	 280 	HIS	E	Protein	S	3
FT	#SUB	266	 285 	HIS	C	74	  93 	GLU	E	Protein	S	2
FT	#SUB	266	 285 	HIS	C	354	 373 	GLN	E	Protein	S	4
FT	#SUB	267	 286 	GLN	C	353	 372 	THR	E	Protein	S	1
FT	#SUB	267	 286 	GLN	C	354	 373 	GLN	E	Protein	S	7
FT	#SUB	267	 286 	GLN	C	355	 374 	HIS	E	Protein	S	6
FT	#SUB	267	 286 	GLN	C	365	 384 	LYS	E	Protein	S	1
FT	#SUB	270	 289 	ASN	C	354	 373 	GLN	E	Protein	S	1
FT	#HET	19	  38 	PRO	C	3	601 	CM5	A	S	1
FT	#HET	20	  39 	LEU	C	3	601 	CM5	A	S	1
FT	#HET	79	  98 	ARG	C	8	500 	HEM	C	S	9
FT	#HET	94	 113 	VAL	C	8	500 	HEM	C	B	1
FT	#HET	95	 114 	ILE	C	8	500 	HEM	C	A	3
FT	#HET	102	 121 	TRP	C	8	500 	HEM	C	S	5
FT	#HET	106	 125 	ARG	C	8	500 	HEM	C	S	5
FT	#HET	160	 179 	ILE	C	8	500 	HEM	C	S	1
FT	#HET	187	 206 	PHE	C	9	501 	3QU	C	S	1
FT	#HET	207	 226 	HIS	C	10	603 	CM5	C	A	15
FT	#HET	208	 227 	PHE	C	10	603 	CM5	C	A	8
FT	#HET	209	 228 	PRO	C	10	603 	CM5	C	A	5
FT	#HET	213	 232 	ARG	C	10	603 	CM5	C	S	4
FT	#HET	276	 295 	LEU	C	8	500 	HEM	C	B	1
FT	#HET	279	 298 	ALA	C	8	500 	HEM	C	A	5
FT	#HET	279	 298 	ALA	C	9	501 	3QU	C	A	8
FT	#HET	280	 299 	GLY	C	8	500 	HEM	C	B	9
FT	#HET	283	 302 	THR	C	8	500 	HEM	C	S	9
FT	#HET	283	 302 	THR	C	9	501 	3QU	C	S	8
FT	#HET	284	 303 	THR	C	8	500 	HEM	C	A	2
FT	#HET	287	 306 	THR	C	8	500 	HEM	C	S	1
FT	#HET	338	 357 	GLN	C	8	500 	HEM	C	S	1
FT	#HET	344	 363 	LEU	C	8	500 	HEM	C	S	4
FT	#HET	344	 363 	LEU	C	9	501 	3QU	C	S	3
FT	#HET	348	 367 	VAL	C	8	500 	HEM	C	A	2
FT	#HET	350	 369 	HIS	C	8	500 	HEM	C	S	6
FT	#HET	373	 392 	LEU	C	8	500 	HEM	C	S	1
FT	#HET	409	 428 	PRO	C	8	500 	HEM	C	B	3
FT	#HET	410	 429 	PHE	C	8	500 	HEM	C	A	10
FT	#HET	411	 430 	SER	C	8	500 	HEM	C	S	6
FT	#HET	415	 434 	ARG	C	8	500 	HEM	C	A	16
FT	#HET	417	 436 	CYS	C	8	500 	HEM	C	A	29
FT	#HET	418	 437 	LEU	C	8	500 	HEM	C	S	4
FT	#HET	419	 438 	GLY	C	8	500 	HEM	C	B	5
FT	#HET	423	 442 	ALA	C	8	500 	HEM	C	S	1
FT	DISORDER	1	8
FT	DISORDER	116	118
FT	DISORDER	474	476
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	462 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDGKR SVEERIQEEA
CC	QCLIEELRKS KGALMDPTFL FQSITANIIC SIVFGKRFHY QDQEFLKMLN LFYQTFSLIS
CC	SVFGQLFELF SGFLKHFPGA HRQVYKNLQE INAYIGHSVE KHRETLDPSA PRDLIDTYLL
CC	HMEKEKSNAH SEFSHQNLNL NTLSLFFAGT ETTSTTLRYG FLLMLKYPHV AERVYREIEQ
CC	VIGPHRPPEL HDRAKMPYTE AVIYEIQRFS DLLPMGVPHI VTQHTSFRGY IIPKDTEVFL
CC	ILSTALHDPH YFEKPDAFNP DHFLDANGAL KKTEAFIPFS LGKRICLGEG IARAELFLFF
CC	TTILQNFSMA SPVAPEDIDL TPQECGVGKI PPTYQIRFLP RH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRD---GKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ***************   ********************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQIRFLPRH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//
ID	3QU8D	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	174	 193 	GLN	D	316	 335 	HIS	A	Protein	A	10
FT	#SUB	175	 194 	GLU	D	316	 335 	HIS	A	Protein	B	1
FT	#SUB	19	  38 	PRO	D	208	 227 	PHE	F	Protein	B	1
FT	#SUB	21	  40 	LEU	D	208	 227 	PHE	F	Protein	S	6
FT	#SUB	208	 227 	PHE	D	19	  38 	PRO	F	Protein	S	1
FT	#SUB	208	 227 	PHE	D	21	  40 	LEU	F	Protein	S	3
FT	#SUB	209	 228 	PRO	D	25	  44 	LEU	F	Protein	B	1
FT	#HET	18	  37 	LEU	D	19	606 	CM5	F	S	2
FT	#HET	19	  38 	PRO	D	19	606 	CM5	F	S	3
FT	#HET	20	  39 	LEU	D	14	607 	CM5	D	A	4
FT	#HET	20	  39 	LEU	D	19	606 	CM5	F	S	4
FT	#HET	21	  40 	LEU	D	14	607 	CM5	D	S	2
FT	#HET	79	  98 	ARG	D	11	500 	HEM	D	S	8
FT	#HET	94	 113 	VAL	D	11	500 	HEM	D	S	1
FT	#HET	95	 114 	ILE	D	11	500 	HEM	D	A	4
FT	#HET	102	 121 	TRP	D	11	500 	HEM	D	S	5
FT	#HET	106	 125 	ARG	D	11	500 	HEM	D	S	6
FT	#HET	160	 179 	ILE	D	11	500 	HEM	D	S	2
FT	#HET	187	 206 	PHE	D	12	501 	3QU	D	S	3
FT	#HET	201	 220 	PHE	D	14	607 	CM5	D	S	6
FT	#HET	203	 222 	GLY	D	14	607 	CM5	D	B	8
FT	#HET	204	 223 	PHE	D	13	604 	CM5	D	S	2
FT	#HET	204	 223 	PHE	D	14	607 	CM5	D	S	1
FT	#HET	206	 225 	LYS	D	14	607 	CM5	D	S	3
FT	#HET	207	 226 	HIS	D	13	604 	CM5	D	A	12
FT	#HET	207	 226 	HIS	D	14	607 	CM5	D	S	3
FT	#HET	208	 227 	PHE	D	13	604 	CM5	D	A	5
FT	#HET	209	 228 	PRO	D	13	604 	CM5	D	A	5
FT	#HET	213	 232 	ARG	D	13	604 	CM5	D	S	3
FT	#HET	276	 295 	LEU	D	11	500 	HEM	D	B	1
FT	#HET	278	 297 	PHE	D	12	501 	3QU	D	S	5
FT	#HET	279	 298 	ALA	D	11	500 	HEM	D	A	4
FT	#HET	279	 298 	ALA	D	12	501 	3QU	D	A	10
FT	#HET	280	 299 	GLY	D	11	500 	HEM	D	B	8
FT	#HET	283	 302 	THR	D	11	500 	HEM	D	S	8
FT	#HET	283	 302 	THR	D	12	501 	3QU	D	S	5
FT	#HET	284	 303 	THR	D	11	500 	HEM	D	A	3
FT	#HET	287	 306 	THR	D	11	500 	HEM	D	S	1
FT	#HET	338	 357 	GLN	D	11	500 	HEM	D	S	1
FT	#HET	344	 363 	LEU	D	11	500 	HEM	D	S	4
FT	#HET	344	 363 	LEU	D	12	501 	3QU	D	S	2
FT	#HET	347	 366 	GLY	D	11	500 	HEM	D	B	1
FT	#HET	348	 367 	VAL	D	11	500 	HEM	D	S	2
FT	#HET	350	 369 	HIS	D	11	500 	HEM	D	S	6
FT	#HET	373	 392 	LEU	D	11	500 	HEM	D	S	1
FT	#HET	409	 428 	PRO	D	11	500 	HEM	D	B	3
FT	#HET	410	 429 	PHE	D	11	500 	HEM	D	A	8
FT	#HET	411	 430 	SER	D	11	500 	HEM	D	S	6
FT	#HET	415	 434 	ARG	D	11	500 	HEM	D	A	14
FT	#HET	417	 436 	CYS	D	11	500 	HEM	D	A	26
FT	#HET	418	 437 	LEU	D	11	500 	HEM	D	S	4
FT	#HET	419	 438 	GLY	D	11	500 	HEM	D	B	4
FT	#HET	423	 442 	ALA	D	11	500 	HEM	D	S	1
FT	DISORDER	1	8
FT	DISORDER	116	121
FT	DISORDER	473	476
CC	SEQUENCE	458 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDSVE ERIQEEAQCL
CC	IEELRKSKGA LMDPTFLFQS ITANIICSIV FGKRFHYQDQ EFLKMLNLFY QTFSLISSVF
CC	GQLFELFSGF LKHFPGAHRQ VYKNLQEINA YIGHSVEKHR ETLDPSAPRD LIDTYLLHME
CC	KEKSNAHSEF SHQNLNLNTL SLFFAGTETT STTLRYGFLL MLKYPHVAER VYREIEQVIG
CC	PHRPPELHDR AKMPYTEAVI YEIQRFSDLL PMGVPHIVTQ HTSFRGYIIP KDTEVFLILS
CC	TALHDPHYFE KPDAFNPDHF LDANGALKKT EAFIPFSLGK RICLGEGIAR AELFLFFTTI
CC	LQNFSMASPV APEDIDLTPQ ECGVGKIPPT YQIRFLPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRD------SVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ***************      *****************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQIRFLPR----
CC	       **********************    
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//
ID	3QU8E	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	18	  37 	LEU	E	209	 228 	PRO	B	Protein	S	1
FT	#SUB	19	  38 	PRO	E	208	 227 	PHE	B	Protein	B	1
FT	#SUB	21	  40 	LEU	E	208	 227 	PHE	B	Protein	S	3
FT	#SUB	208	 227 	PHE	E	21	  40 	LEU	B	Protein	S	1
FT	#SUB	10	  29 	LYS	E	217	 236 	LYS	C	Protein	S	2
FT	#SUB	72	  91 	LYS	E	231	 250 	GLU	C	Protein	S	1
FT	#SUB	74	  93 	GLU	E	266	 285 	HIS	C	Protein	S	2
FT	#SUB	100	 119 	ASN	E	260	 279 	ALA	C	Protein	S	5
FT	#SUB	261	 280 	HIS	E	261	 280 	HIS	C	Protein	S	3
FT	#SUB	353	 372 	THR	E	267	 286 	GLN	C	Protein	B	1
FT	#SUB	354	 373 	GLN	E	266	 285 	HIS	C	Protein	S	4
FT	#SUB	354	 373 	GLN	E	267	 286 	GLN	C	Protein	A	7
FT	#SUB	354	 373 	GLN	E	270	 289 	ASN	C	Protein	S	1
FT	#SUB	355	 374 	HIS	E	88	 107 	PHE	C	Protein	S	9
FT	#SUB	355	 374 	HIS	E	220	 239 	GLN	C	Protein	S	9
FT	#SUB	355	 374 	HIS	E	223	 242 	ASN	C	Protein	S	1
FT	#SUB	355	 374 	HIS	E	267	 286 	GLN	C	Protein	A	6
FT	#SUB	357	 376 	SER	E	224	 243 	ALA	C	Protein	S	2
FT	#SUB	362	 381 	ILE	E	220	 239 	GLN	C	Protein	S	4
FT	#SUB	364	 383 	PRO	E	216	 235 	TYR	C	Protein	S	2
FT	#SUB	365	 384 	LYS	E	92	 111 	TYR	C	Protein	S	4
FT	#SUB	365	 384 	LYS	E	267	 286 	GLN	C	Protein	S	1
FT	#HET	16	  35 	ARG	E	10	603 	CM5	C	S	3
FT	#HET	17	  36 	PRO	E	10	603 	CM5	C	B	1
FT	#HET	19	  38 	PRO	E	10	603 	CM5	C	S	2
FT	#HET	79	  98 	ARG	E	15	500 	HEM	E	S	7
FT	#HET	94	 113 	VAL	E	15	500 	HEM	E	A	3
FT	#HET	95	 114 	ILE	E	15	500 	HEM	E	A	8
FT	#HET	102	 121 	TRP	E	15	500 	HEM	E	S	5
FT	#HET	106	 125 	ARG	E	15	500 	HEM	E	S	5
FT	#HET	160	 179 	ILE	E	15	500 	HEM	E	S	2
FT	#HET	187	 206 	PHE	E	16	501 	3QU	E	S	2
FT	#HET	204	 223 	PHE	E	17	605 	CM5	E	S	1
FT	#HET	207	 226 	HIS	E	17	605 	CM5	E	B	7
FT	#HET	208	 227 	PHE	E	17	605 	CM5	E	A	16
FT	#HET	209	 228 	PRO	E	17	605 	CM5	E	S	2
FT	#HET	213	 232 	ARG	E	17	605 	CM5	E	S	4
FT	#HET	276	 295 	LEU	E	15	500 	HEM	E	A	2
FT	#HET	278	 297 	PHE	E	16	501 	3QU	E	S	8
FT	#HET	279	 298 	ALA	E	15	500 	HEM	E	A	6
FT	#HET	279	 298 	ALA	E	16	501 	3QU	E	A	10
FT	#HET	280	 299 	GLY	E	15	500 	HEM	E	B	9
FT	#HET	283	 302 	THR	E	15	500 	HEM	E	S	8
FT	#HET	283	 302 	THR	E	16	501 	3QU	E	S	4
FT	#HET	284	 303 	THR	E	15	500 	HEM	E	S	1
FT	#HET	287	 306 	THR	E	15	500 	HEM	E	S	1
FT	#HET	338	 357 	GLN	E	15	500 	HEM	E	S	1
FT	#HET	344	 363 	LEU	E	15	500 	HEM	E	S	2
FT	#HET	344	 363 	LEU	E	16	501 	3QU	E	S	1
FT	#HET	347	 366 	GLY	E	15	500 	HEM	E	B	1
FT	#HET	348	 367 	VAL	E	15	500 	HEM	E	S	2
FT	#HET	350	 369 	HIS	E	15	500 	HEM	E	S	6
FT	#HET	373	 392 	LEU	E	15	500 	HEM	E	S	1
FT	#HET	409	 428 	PRO	E	15	500 	HEM	E	B	3
FT	#HET	410	 429 	PHE	E	15	500 	HEM	E	A	13
FT	#HET	411	 430 	SER	E	15	500 	HEM	E	S	6
FT	#HET	415	 434 	ARG	E	15	500 	HEM	E	A	17
FT	#HET	416	 435 	ILE	E	15	500 	HEM	E	B	2
FT	#HET	417	 436 	CYS	E	15	500 	HEM	E	A	28
FT	#HET	418	 437 	LEU	E	15	500 	HEM	E	S	4
FT	#HET	419	 438 	GLY	E	15	500 	HEM	E	B	2
FT	#HET	423	 442 	ALA	E	15	500 	HEM	E	S	2
FT	DISORDER	1	8
FT	DISORDER	116	121
FT	DISORDER	474	476
CC	SEQUENCE	459 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDSVE ERIQEEAQCL
CC	IEELRKSKGA LMDPTFLFQS ITANIICSIV FGKRFHYQDQ EFLKMLNLFY QTFSLISSVF
CC	GQLFELFSGF LKHFPGAHRQ VYKNLQEINA YIGHSVEKHR ETLDPSAPRD LIDTYLLHME
CC	KEKSNAHSEF SHQNLNLNTL SLFFAGTETT STTLRYGFLL MLKYPHVAER VYREIEQVIG
CC	PHRPPELHDR AKMPYTEAVI YEIQRFSDLL PMGVPHIVTQ HTSFRGYIIP KDTEVFLILS
CC	TALHDPHYFE KPDAFNPDHF LDANGALKKT EAFIPFSLGK RICLGEGIAR AELFLFFTTI
CC	LQNFSMASPV APEDIDLTPQ ECGVGKIPPT YQIRFLPRH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRD------SVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ***************      *****************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQIRFLPRH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//
ID	3QU8F	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3QU8
DE	Cytochrome P450 2B6
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.220
FT	#SUB	19	  38 	PRO	F	208	 227 	PHE	D	Protein	B	1
FT	#SUB	21	  40 	LEU	F	208	 227 	PHE	D	Protein	S	3
FT	#SUB	25	  44 	LEU	F	209	 228 	PRO	D	Protein	S	1
FT	#SUB	208	 227 	PHE	F	19	  38 	PRO	D	Protein	S	1
FT	#SUB	208	 227 	PHE	F	21	  40 	LEU	D	Protein	S	6
FT	#HET	79	  98 	ARG	F	18	500 	HEM	F	S	6
FT	#HET	94	 113 	VAL	F	18	500 	HEM	F	S	1
FT	#HET	95	 114 	ILE	F	18	500 	HEM	F	S	1
FT	#HET	102	 121 	TRP	F	18	500 	HEM	F	S	5
FT	#HET	106	 125 	ARG	F	18	500 	HEM	F	S	6
FT	#HET	160	 179 	ILE	F	18	500 	HEM	F	S	2
FT	#HET	204	 223 	PHE	F	14	607 	CM5	D	S	2
FT	#HET	204	 223 	PHE	F	19	606 	CM5	F	S	1
FT	#HET	207	 226 	HIS	F	19	606 	CM5	F	B	6
FT	#HET	208	 227 	PHE	F	19	606 	CM5	F	A	12
FT	#HET	209	 228 	PRO	F	19	606 	CM5	F	S	3
FT	#HET	213	 232 	ARG	F	19	606 	CM5	F	S	5
FT	#HET	276	 295 	LEU	F	18	500 	HEM	F	A	4
FT	#HET	279	 298 	ALA	F	18	500 	HEM	F	A	10
FT	#HET	280	 299 	GLY	F	18	500 	HEM	F	B	11
FT	#HET	283	 302 	THR	F	18	500 	HEM	F	S	11
FT	#HET	284	 303 	THR	F	18	500 	HEM	F	A	4
FT	#HET	287	 306 	THR	F	18	500 	HEM	F	S	1
FT	#HET	338	 357 	GLN	F	18	500 	HEM	F	S	1
FT	#HET	344	 363 	LEU	F	18	500 	HEM	F	S	4
FT	#HET	348	 367 	VAL	F	18	500 	HEM	F	S	2
FT	#HET	350	 369 	HIS	F	18	500 	HEM	F	S	7
FT	#HET	373	 392 	LEU	F	18	500 	HEM	F	S	1
FT	#HET	409	 428 	PRO	F	18	500 	HEM	F	B	3
FT	#HET	410	 429 	PHE	F	18	500 	HEM	F	S	8
FT	#HET	411	 430 	SER	F	18	500 	HEM	F	S	5
FT	#HET	414	 433 	LYS	F	18	500 	HEM	F	B	1
FT	#HET	415	 434 	ARG	F	18	500 	HEM	F	A	22
FT	#HET	417	 436 	CYS	F	18	500 	HEM	F	A	25
FT	#HET	418	 437 	LEU	F	18	500 	HEM	F	A	9
FT	#HET	419	 438 	GLY	F	18	500 	HEM	F	B	1
FT	#HET	423	 442 	ALA	F	18	500 	HEM	F	S	1
FT	DISORDER	1	8
FT	DISORDER	116	121
FT	DISORDER	468	476
CC	SEQUENCE	453 AA (ATOM);
CC	GKLPPGPRPL PLLGNLLQMD RRGLLKSFLR FREKYGDVFT VHLGPRPVVM LCGVEAIREA
CC	LVDKAEAFSG RGKIAMVDPF FRGYGVIFAN GNRWKVLRRF SVTTMRDSVE ERIQEEAQCL
CC	IEELRKSKGA LMDPTFLFQS ITANIICSIV FGKRFHYQDQ EFLKMLNLFY QTFSLISSVF
CC	GQLFELFSGF LKHFPGAHRQ VYKNLQEINA YIGHSVEKHR ETLDPSAPRD LIDTYLLHME
CC	KEKSNAHSEF SHQNLNLNTL SLFFAGTETT STTLRYGFLL MLKYPHVAER VYREIEQVIG
CC	PHRPPELHDR AKMPYTEAVI YEIQRFSDLL PMGVPHIVTQ HTSFRGYIIP KDTEVFLILS
CC	TALHDPHYFE KPDAFNPDHF LDANGALKKT EAFIPFSLGK RICLGEGIAR AELFLFFTTI
CC	LQNFSMASPV APEDIDLTPQ ECGVGKIPPT YQI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	ATOM   --------GKLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVH
CC	               ******************************************
CC	SEQRES LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	ATOM   LGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGN
CC	       **************************************************
CC	SEQRES RWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTF
CC	ATOM   RWKVLRRFSVTTMRD------SVEERIQEEAQCLIEELRKSKGALMDPTF
CC	       ***************      *****************************
CC	SEQRES LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	ATOM   LFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFEL
CC	       **************************************************
CC	SEQRES FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	ATOM   FSGFLKHFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPRDLIDTYL
CC	       **************************************************
CC	SEQRES LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	ATOM   VAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPH
CC	       **************************************************
CC	SEQRES IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	ATOM   IVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGA
CC	       **************************************************
CC	SEQRES LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	ATOM   LKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDID
CC	       **************************************************
CC	SEQRES LTPQECGVGKIPPTYQIRFLPRHHHH
CC	ATOM   LTPQECGVGKIPPTYQI---------
CC	       *****************         
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPRPLPL LGNLLQMDRR GLLKSFLRFR EKYGDVFTVH LGPRPVVMLC
	GVEAIREALV DKAEAFSGRG KIAMVDPFFR GYGVIFANGN RWKVLRRFSV TTMRDFGMGK
	RSVEERIQEE AQCLIEELRK SKGALMDPTF LFQSITANII CSIVFGKRFH YQDQEFLKML
	NLFYQTFSLI SSVFGQLFEL FSGFLKHFPG AHRQVYKNLQ EINAYIGHSV EKHRETLDPS
	APRDLIDTYL LHMEKEKSNA HSEFSHQNLN LNTLSLFFAG TETTSTTLRY GFLLMLKYPH
	VAERVYREIE QVIGPHRPPE LHDRAKMPYT EAVIYEIQRF SDLLPMGVPH IVTQHTSFRG
	YIIPKDTEVF LILSTALHDP HYFEKPDAFN PDHFLDANGA LKKTEAFIPF SLGKRICLGE
	GIARAELFLF FTTILQNFSM ASPVAPEDID LTPQECGVGK IPPTYQIRFL PRHHHH
//