ID	3PRFA	STANDARD;	PRT;	307	AA.
DT	CONVERTED FROM PDB (SEQRES) 3PRF
DE	Serine/threonine-protein kinase B-raf
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.900
CC	R-Factor	0.271
FT	#SUB	29	 448 	ASP	A	87	 506 	ARG	B	Protein	S	7
FT	#SUB	29	 448 	ASP	A	88	 507 	LYS	B	Protein	A	3
FT	#SUB	31	 450 	TRP	A	87	 506 	ARG	B	Protein	S	2
FT	#SUB	31	 450 	TRP	A	88	 507 	LYS	B	Protein	S	5
FT	#SUB	31	 450 	TRP	A	90	 509 	ARG	B	Protein	S	9
FT	#SUB	58	 477 	HIS	A	91	 510 	HIS	B	Protein	A	5
FT	#SUB	58	 477 	HIS	A	143	 562 	GLN	B	Protein	B	7
FT	#SUB	58	 477 	HIS	A	146	 565 	ASP	B	Protein	S	3
FT	#SUB	58	 477 	HIS	A	150	 569 	ALA	B	Protein	S	2
FT	#SUB	59	 478 	GLY	A	143	 562 	GLN	B	Protein	B	5
FT	#SUB	86	 505 	LEU	A	90	 509 	ARG	B	Protein	B	1
FT	#SUB	87	 506 	ARG	A	31	 450 	TRP	B	Protein	B	2
FT	#SUB	87	 506 	ARG	A	90	 509 	ARG	B	Protein	B	3
FT	#SUB	88	 507 	LYS	A	29	 448 	ASP	B	Protein	S	4
FT	#SUB	88	 507 	LYS	A	31	 450 	TRP	B	Protein	B	3
FT	#SUB	89	 508 	THR	A	90	 509 	ARG	B	Protein	B	4
FT	#SUB	90	 509 	ARG	A	31	 450 	TRP	B	Protein	S	8
FT	#SUB	90	 509 	ARG	A	86	 505 	LEU	B	Protein	S	1
FT	#SUB	90	 509 	ARG	A	87	 506 	ARG	B	Protein	S	3
FT	#SUB	90	 509 	ARG	A	89	 508 	THR	B	Protein	S	5
FT	#SUB	90	 509 	ARG	A	90	 509 	ARG	B	Protein	S	4
FT	#SUB	90	 509 	ARG	A	96	 515 	LEU	B	Protein	S	1
FT	#SUB	90	 509 	ARG	A	97	 516 	PHE	B	Protein	S	14
FT	#SUB	90	 509 	ARG	A	98	 517 	MET	B	Protein	B	1
FT	#SUB	91	 510 	HIS	A	58	 477 	HIS	B	Protein	S	5
FT	#SUB	91	 510 	HIS	A	96	 515 	LEU	B	Protein	B	3
FT	#SUB	92	 511 	VAL	A	96	 515 	LEU	B	Protein	B	1
FT	#SUB	92	 511 	VAL	A	98	 517 	MET	B	Protein	B	1
FT	#SUB	92	 511 	VAL	A	111	 530 	GLN	B	Protein	S	1
FT	#SUB	96	 515 	LEU	A	90	 509 	ARG	B	Protein	S	1
FT	#SUB	96	 515 	LEU	A	91	 510 	HIS	B	Protein	S	2
FT	#SUB	96	 515 	LEU	A	92	 511 	VAL	B	Protein	S	1
FT	#SUB	96	 515 	LEU	A	96	 515 	LEU	B	Protein	S	1
FT	#SUB	97	 516 	PHE	A	90	 509 	ARG	B	Protein	A	10
FT	#SUB	98	 517 	MET	A	90	 509 	ARG	B	Protein	S	1
FT	#SUB	98	 517 	MET	A	92	 511 	VAL	B	Protein	S	2
FT	#SUB	143	 562 	GLN	A	58	 477 	HIS	B	Protein	S	7
FT	#SUB	143	 562 	GLN	A	59	 478 	GLY	B	Protein	S	5
FT	#SUB	147	 566 	TYR	A	58	 477 	HIS	B	Protein	S	1
FT	#SUB	150	 569 	ALA	A	58	 477 	HIS	B	Protein	S	2
FT	#SUB	167	 586 	GLU	A	169	 588 	LEU	B	Protein	S	1
FT	#SUB	169	 588 	LEU	A	167	 586 	GLU	B	Protein	S	1
FT	#HET	44	 463 	ILE	A	1	727 	FP3	A	A	5
FT	#HET	45	 464 	GLY	A	1	727 	FP3	A	B	1
FT	#HET	46	 465 	SER	A	1	727 	FP3	A	B	1
FT	#HET	52	 471 	VAL	A	1	727 	FP3	A	S	7
FT	#HET	62	 481 	ALA	A	1	727 	FP3	A	S	4
FT	#HET	64	 483 	LYS	A	1	727 	FP3	A	S	4
FT	#HET	82	 501 	GLU	A	1	727 	FP3	A	S	2
FT	#HET	95	 514 	LEU	A	1	727 	FP3	A	S	1
FT	#HET	108	 527 	ILE	A	1	727 	FP3	A	S	2
FT	#HET	110	 529 	THR	A	1	727 	FP3	A	S	2
FT	#HET	111	 530 	GLN	A	1	727 	FP3	A	B	2
FT	#HET	112	 531 	TRP	A	1	727 	FP3	A	A	5
FT	#HET	113	 532 	CYS	A	1	727 	FP3	A	A	7
FT	#HET	164	 583 	PHE	A	1	727 	FP3	A	S	10
FT	#HET	174	 593 	GLY	A	1	727 	FP3	A	B	3
FT	#HET	175	 594 	ASP	A	1	727 	FP3	A	A	4
FT	DISORDER	1	28
FT	DISORDER	182	195
FT	DISORDER	305	307
CC	SEQUENCE	262 AA (ATOM);
CC	DDWEIPDGQI TVGQRIGSGS FGTVYKGKWH GDVAVKMLNV TAPTPQQLQA FKNEVGVLRK
CC	TRHVNILLFM GYSTKPQLAI VTQWCEGSSL YHHLHIIETK FEMIKLIDIA RQTAQGMDYL
CC	HAKSIIHRDL KSNNIFLHED LTVKIGDFGL ATVGSILWMA PEVIRMQDKN PYSFQSDVYA
CC	FGIVLYELMT GQLPYSNINN RDQIIFMVGR GYLSPDLSKV RSNCPKAMKR LMAECLKKKR
CC	DERPLFPQIL ASIELLARSL PK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MDRGSHHHHHHGSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFG
CC	ATOM   ----------------------------DDWEIPDGQITVGQRIGSGSFG
CC	                                   **********************
CC	SEQRES TVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY
CC	ATOM   TVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY
CC	       **************************************************
CC	SEQRES STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHA
CC	ATOM   STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHA
CC	       **************************************************
CC	SEQRES KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILW
CC	ATOM   KSIIHRDLKSNNIFLHEDLTVKIGDFGLATV--------------GSILW
CC	       *******************************              *****
CC	SEQRES MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV
CC	ATOM   MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV
CC	       **************************************************
CC	SEQRES GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLAR
CC	ATOM   GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLAR
CC	       **************************************************
CC	SEQRES SLPKIHR
CC	ATOM   SLPK---
CC	       ****   
SQ	SEQUENCE	307 AA;      MW;         CN;
	MDRGSHHHHH HGSEDRNRMK TLGRRDSSDD WEIPDGQITV GQRIGSGSFG TVYKGKWHGD
	VAVKMLNVTA PTPQQLQAFK NEVGVLRKTR HVNILLFMGY STKPQLAIVT QWCEGSSLYH
	HLHIIETKFE MIKLIDIARQ TAQGMDYLHA KSIIHRDLKS NNIFLHEDLT VKIGDFGLAT
	VKSRWSGSHQ FEQLSGSILW MAPEVIRMQD KNPYSFQSDV YAFGIVLYEL MTGQLPYSNI
	NNRDQIIFMV GRGYLSPDLS KVRSNCPKAM KRLMAECLKK KRDERPLFPQ ILASIELLAR
	SLPKIHR
//
ID	3PRFB	STANDARD;	PRT;	307	AA.
DT	CONVERTED FROM PDB (SEQRES) 3PRF
DE	Serine/threonine-protein kinase B-raf
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.900
CC	R-Factor	0.271
FT	#SUB	29	 448 	ASP	B	88	 507 	LYS	A	Protein	B	4
FT	#SUB	31	 450 	TRP	B	87	 506 	ARG	A	Protein	S	2
FT	#SUB	31	 450 	TRP	B	88	 507 	LYS	A	Protein	S	3
FT	#SUB	31	 450 	TRP	B	90	 509 	ARG	A	Protein	S	8
FT	#SUB	58	 477 	HIS	B	91	 510 	HIS	A	Protein	A	5
FT	#SUB	58	 477 	HIS	B	143	 562 	GLN	A	Protein	A	7
FT	#SUB	58	 477 	HIS	B	147	 566 	TYR	A	Protein	S	1
FT	#SUB	58	 477 	HIS	B	150	 569 	ALA	A	Protein	S	2
FT	#SUB	59	 478 	GLY	B	143	 562 	GLN	A	Protein	B	5
FT	#SUB	86	 505 	LEU	B	90	 509 	ARG	A	Protein	B	1
FT	#SUB	87	 506 	ARG	B	29	 448 	ASP	A	Protein	A	7
FT	#SUB	87	 506 	ARG	B	31	 450 	TRP	A	Protein	B	2
FT	#SUB	87	 506 	ARG	B	90	 509 	ARG	A	Protein	B	3
FT	#SUB	88	 507 	LYS	B	29	 448 	ASP	A	Protein	S	3
FT	#SUB	88	 507 	LYS	B	31	 450 	TRP	A	Protein	B	5
FT	#SUB	89	 508 	THR	B	90	 509 	ARG	A	Protein	B	5
FT	#SUB	90	 509 	ARG	B	31	 450 	TRP	A	Protein	S	9
FT	#SUB	90	 509 	ARG	B	86	 505 	LEU	A	Protein	S	1
FT	#SUB	90	 509 	ARG	B	87	 506 	ARG	A	Protein	S	3
FT	#SUB	90	 509 	ARG	B	89	 508 	THR	A	Protein	S	4
FT	#SUB	90	 509 	ARG	B	90	 509 	ARG	A	Protein	S	4
FT	#SUB	90	 509 	ARG	B	96	 515 	LEU	A	Protein	S	1
FT	#SUB	90	 509 	ARG	B	97	 516 	PHE	A	Protein	S	10
FT	#SUB	90	 509 	ARG	B	98	 517 	MET	A	Protein	B	1
FT	#SUB	91	 510 	HIS	B	58	 477 	HIS	A	Protein	S	5
FT	#SUB	91	 510 	HIS	B	96	 515 	LEU	A	Protein	B	2
FT	#SUB	92	 511 	VAL	B	96	 515 	LEU	A	Protein	B	1
FT	#SUB	92	 511 	VAL	B	98	 517 	MET	A	Protein	A	2
FT	#SUB	96	 515 	LEU	B	90	 509 	ARG	A	Protein	S	1
FT	#SUB	96	 515 	LEU	B	91	 510 	HIS	A	Protein	S	3
FT	#SUB	96	 515 	LEU	B	92	 511 	VAL	A	Protein	S	1
FT	#SUB	96	 515 	LEU	B	96	 515 	LEU	A	Protein	S	1
FT	#SUB	97	 516 	PHE	B	90	 509 	ARG	A	Protein	A	14
FT	#SUB	98	 517 	MET	B	90	 509 	ARG	A	Protein	S	1
FT	#SUB	98	 517 	MET	B	92	 511 	VAL	A	Protein	S	1
FT	#SUB	111	 530 	GLN	B	92	 511 	VAL	A	Protein	S	1
FT	#SUB	143	 562 	GLN	B	58	 477 	HIS	A	Protein	S	7
FT	#SUB	143	 562 	GLN	B	59	 478 	GLY	A	Protein	S	5
FT	#SUB	146	 565 	ASP	B	58	 477 	HIS	A	Protein	A	3
FT	#SUB	150	 569 	ALA	B	58	 477 	HIS	A	Protein	S	2
FT	#SUB	167	 586 	GLU	B	169	 588 	LEU	A	Protein	S	1
FT	#SUB	169	 588 	LEU	B	167	 586 	GLU	A	Protein	S	1
FT	#HET	44	 463 	ILE	B	2	727 	FP3	B	S	2
FT	#HET	46	 465 	SER	B	2	727 	FP3	B	B	2
FT	#HET	52	 471 	VAL	B	2	727 	FP3	B	S	4
FT	#HET	62	 481 	ALA	B	2	727 	FP3	B	S	2
FT	#HET	64	 483 	LYS	B	2	727 	FP3	B	S	6
FT	#HET	82	 501 	GLU	B	2	727 	FP3	B	S	2
FT	#HET	95	 514 	LEU	B	2	727 	FP3	B	S	2
FT	#HET	108	 527 	ILE	B	2	727 	FP3	B	S	1
FT	#HET	110	 529 	THR	B	2	727 	FP3	B	S	1
FT	#HET	111	 530 	GLN	B	2	727 	FP3	B	B	1
FT	#HET	113	 532 	CYS	B	2	727 	FP3	B	A	6
FT	#HET	164	 583 	PHE	B	2	727 	FP3	B	S	13
FT	#HET	175	 594 	ASP	B	2	727 	FP3	B	A	5
FT	DISORDER	1	28
FT	DISORDER	182	195
FT	DISORDER	305	307
CC	SEQUENCE	262 AA (ATOM);
CC	DDWEIPDGQI TVGQRIGSGS FGTVYKGKWH GDVAVKMLNV TAPTPQQLQA FKNEVGVLRK
CC	TRHVNILLFM GYSTKPQLAI VTQWCEGSSL YHHLHIIETK FEMIKLIDIA RQTAQGMDYL
CC	HAKSIIHRDL KSNNIFLHED LTVKIGDFGL ATVGSILWMA PEVIRMQDKN PYSFQSDVYA
CC	FGIVLYELMT GQLPYSNINN RDQIIFMVGR GYLSPDLSKV RSNCPKAMKR LMAECLKKKR
CC	DERPLFPQIL ASIELLARSL PK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MDRGSHHHHHHGSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFG
CC	ATOM   ----------------------------DDWEIPDGQITVGQRIGSGSFG
CC	                                   **********************
CC	SEQRES TVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY
CC	ATOM   TVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGY
CC	       **************************************************
CC	SEQRES STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHA
CC	ATOM   STKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHA
CC	       **************************************************
CC	SEQRES KSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILW
CC	ATOM   KSIIHRDLKSNNIFLHEDLTVKIGDFGLATV--------------GSILW
CC	       *******************************              *****
CC	SEQRES MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV
CC	ATOM   MAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMV
CC	       **************************************************
CC	SEQRES GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLAR
CC	ATOM   GRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLAR
CC	       **************************************************
CC	SEQRES SLPKIHR
CC	ATOM   SLPK---
CC	       ****   
SQ	SEQUENCE	307 AA;      MW;         CN;
	MDRGSHHHHH HGSEDRNRMK TLGRRDSSDD WEIPDGQITV GQRIGSGSFG TVYKGKWHGD
	VAVKMLNVTA PTPQQLQAFK NEVGVLRKTR HVNILLFMGY STKPQLAIVT QWCEGSSLYH
	HLHIIETKFE MIKLIDIARQ TAQGMDYLHA KSIIHRDLKS NNIFLHEDLT VKIGDFGLAT
	VKSRWSGSHQ FEQLSGSILW MAPEVIRMQD KNPYSFQSDV YAFGIVLYEL MTGQLPYSNI
	NNRDQIIFMV GRGYLSPDLS KVRSNCPKAM KRLMAECLKK KRDERPLFPQ ILASIELLAR
	SLPKIHR
//