ID	3PP1A	STANDARD;	PRT;	328	AA.
DT	CONVERTED FROM PDB (SEQRES) 3PP1
DE	Dual specificity mitogen-activated protein kinase kinase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.700
CC	R-Factor	0.184
FT	#HET	2	  62 	GLU	A	4	590 	ACT	A	A	3
FT	#HET	3	  63 	LEU	A	4	590 	ACT	A	A	8
FT	#HET	14	  74 	LEU	A	1	400 	ATP	A	A	3
FT	#HET	15	  75 	GLY	A	1	400 	ATP	A	B	4
FT	#HET	16	  76 	ALA	A	1	400 	ATP	A	B	4
FT	#HET	17	  77 	GLY	A	1	400 	ATP	A	B	7
FT	#HET	18	  78 	ASN	A	1	400 	ATP	A	B	4
FT	#HET	18	  78 	ASN	A	3	500 	IZG	A	B	3
FT	#HET	20	  80 	GLY	A	1	400 	ATP	A	B	2
FT	#HET	20	  80 	GLY	A	3	500 	IZG	A	B	3
FT	#HET	22	  82 	VAL	A	1	400 	ATP	A	S	3
FT	#HET	35	  95 	ALA	A	1	400 	ATP	A	S	3
FT	#HET	37	  97 	LYS	A	1	400 	ATP	A	S	6
FT	#HET	37	  97 	LYS	A	2	410 	MG	A	S	1
FT	#HET	37	  97 	LYS	A	3	500 	IZG	A	S	12
FT	#HET	39	  99 	ILE	A	3	500 	IZG	A	S	1
FT	#HET	55	 115 	LEU	A	3	500 	IZG	A	S	1
FT	#HET	56	 116 	GLN	A	4	590 	ACT	A	S	3
FT	#HET	58	 118 	LEU	A	3	500 	IZG	A	S	1
FT	#HET	59	 119 	HIS	A	4	590 	ACT	A	S	1
FT	#HET	67	 127 	VAL	A	3	500 	IZG	A	A	2
FT	#HET	71	 131 	GLY	A	4	590 	ACT	A	B	5
FT	#HET	72	 132 	ALA	A	4	590 	ACT	A	B	7
FT	#HET	81	 141 	ILE	A	3	500 	IZG	A	S	6
FT	#HET	83	 143 	MET	A	1	400 	ATP	A	S	2
FT	#HET	83	 143 	MET	A	3	500 	IZG	A	S	4
FT	#HET	84	 144 	GLU	A	1	400 	ATP	A	B	3
FT	#HET	85	 145 	HIS	A	1	400 	ATP	A	B	2
FT	#HET	86	 146 	MET	A	1	400 	ATP	A	A	6
FT	#HET	90	 150 	SER	A	1	400 	ATP	A	S	4
FT	#HET	92	 152 	ASP	A	1	400 	ATP	A	S	1
FT	#HET	93	 153 	GLN	A	1	400 	ATP	A	S	4
FT	#HET	132	 192 	LYS	A	1	400 	ATP	A	S	6
FT	#HET	134	 194 	SER	A	1	400 	ATP	A	A	8
FT	#HET	135	 195 	ASN	A	1	400 	ATP	A	S	1
FT	#HET	135	 195 	ASN	A	2	410 	MG	A	S	3
FT	#HET	137	 197 	LEU	A	1	400 	ATP	A	S	4
FT	#HET	148	 208 	ASP	A	1	400 	ATP	A	S	3
FT	#HET	148	 208 	ASP	A	2	410 	MG	A	S	3
FT	#HET	148	 208 	ASP	A	3	500 	IZG	A	A	16
FT	#HET	149	 209 	PHE	A	3	500 	IZG	A	A	10
FT	#HET	150	 210 	GLY	A	3	500 	IZG	A	B	5
FT	#HET	151	 211 	VAL	A	3	500 	IZG	A	A	6
FT	#HET	152	 212 	SER	A	3	500 	IZG	A	A	2
FT	#HET	155	 215 	LEU	A	3	500 	IZG	A	S	8
FT	#HET	156	 216 	ILE	A	3	500 	IZG	A	A	2
FT	DISORDER	216	246
FT	DISORDER	323	328
CC	SEQUENCE	291 AA (ATOM);
CC	MELKDDDFEK ISELGAGNGG VVFKVSHKPS GLVMARKLIH LEIKPAIRNQ IIRELQVLHE
CC	CNSPYIVGFY GAFYSDGEIS ICMEHMDGGS LDQVLKKAGR IPEQILGKVS IAVIKGLTYL
CC	REKHKIMHRD VKPSNILVNS RGEIKLCDFG VSGQLIDSMA NSFVGTRSYM SPERLQGTHY
CC	SVQSDIWSMG LSLVEMAVGR YPIPPPDAKE LELMFPMAIF ELLDYIVNEP PPKLPSGVFS
CC	LEFQDFVNKC LIKNPAERAD LKQLMVHAFI KRSDAEEVDF AGWLCSTIGL N
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQ
CC	ATOM   MELKDDDFEKISELGAGNGGVVFKVSHKPSGLVMARKLIHLEIKPAIRNQ
CC	       **************************************************
CC	SEQRES IIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR
CC	ATOM   IIRELQVLHECNSPYIVGFYGAFYSDGEISICMEHMDGGSLDQVLKKAGR
CC	       **************************************************
CC	SEQRES IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFG
CC	ATOM   IPEQILGKVSIAVIKGLTYLREKHKIMHRDVKPSNILVNSRGEIKLCDFG
CC	       **************************************************
CC	SEQRES VSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR
CC	ATOM   VSGQLIDSMANSFVGTRSYMSPERLQGTHYSVQSDIWSMGLSLVEMAVGR
CC	       **************************************************
CC	SEQRES YPIPPPDAKELELMFGCQVEGDAAETPPRPRTPGRPLSSYGMDSRPPMAI
CC	ATOM   YPIPPPDAKELELMF-------------------------------PMAI
CC	       ***************                               ****
CC	SEQRES FELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
CC	ATOM   FELLDYIVNEPPPKLPSGVFSLEFQDFVNKCLIKNPAERADLKQLMVHAF
CC	       **************************************************
CC	SEQRES IKRSDAEEVDFAGWLCSTIGLNHHHHHH
CC	ATOM   IKRSDAEEVDFAGWLCSTIGLN------
CC	       **********************      
SQ	SEQUENCE	328 AA;      MW;         CN;
	MELKDDDFEK ISELGAGNGG VVFKVSHKPS GLVMARKLIH LEIKPAIRNQ IIRELQVLHE
	CNSPYIVGFY GAFYSDGEIS ICMEHMDGGS LDQVLKKAGR IPEQILGKVS IAVIKGLTYL
	REKHKIMHRD VKPSNILVNS RGEIKLCDFG VSGQLIDSMA NSFVGTRSYM SPERLQGTHY
	SVQSDIWSMG LSLVEMAVGR YPIPPPDAKE LELMFGCQVE GDAAETPPRP RTPGRPLSSY
	GMDSRPPMAI FELLDYIVNE PPPKLPSGVF SLEFQDFVNK CLIKNPAERA DLKQLMVHAF
	IKRSDAEEVD FAGWLCSTIG LNHHHHHH
//