ID	3PJ2A	STANDARD;	PRT;	274	AA.
DT	CONVERTED FROM PDB (SEQRES) 3PJ2
DE	Tyrosine-protein kinase BTK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.750
CC	R-Factor	0.231
FT	#HET	22	 407 	GLU	A	1	1 	04K	A	B	2
FT	#HET	23	 408 	LEU	A	1	1 	04K	A	A	4
FT	#HET	31	 416 	VAL	A	1	1 	04K	A	S	5
FT	#HET	43	 428 	ALA	A	1	1 	04K	A	S	3
FT	#HET	45	 430 	LYS	A	1	1 	04K	A	S	1
FT	#HET	64	 449 	MET	A	1	1 	04K	A	S	5
FT	#HET	73	 458 	VAL	A	1	1 	04K	A	S	2
FT	#HET	89	 474 	THR	A	1	1 	04K	A	S	3
FT	#HET	90	 475 	GLU	A	1	1 	04K	A	B	1
FT	#HET	91	 476 	TYR	A	1	1 	04K	A	S	4
FT	#HET	92	 477 	MET	A	1	1 	04K	A	A	12
FT	#HET	95	 480 	GLY	A	1	1 	04K	A	B	8
FT	#HET	143	 528 	LEU	A	1	1 	04K	A	S	4
FT	#HET	153	 538 	SER	A	1	1 	04K	A	S	1
FT	#HET	154	 539 	ASP	A	1	1 	04K	A	A	5
FT	#HET	155	 540 	PHE	A	1	1 	04K	A	S	1
FT	DISORDER	1	5
FT	DISORDER	26	28
FT	DISORDER	156	173
CC	SEQUENCE	248 AA (ATOM);
CC	GYGSWEIDPK DLTFLKELGT GVVKYGKWRG QYDVAIKMIK EGSMSEDEFI EEAKVMMNLS
CC	HEKLVQLYGV CTKQRPIFII TEYMANGCLL NYLREMRHRF QTQQLLEMCK DVCEAMEYLE
CC	SKQFLHRDLA ARNCLVNDQG VVKVSDFFPV RWSPPEVLMY SKFSSKSDIW AFGVLMWEIY
CC	SLGKMPYERF TNSETAEHIA QGLRLYRPHL ASEKVYTIMY SCWHEKADER PTFKILLSNI
CC	LDVMDEES
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEG
CC	ATOM   -----GYGSWEIDPKDLTFLKELGT---GVVKYGKWRGQYDVAIKMIKEG
CC	            ********************   **********************
CC	SEQRES SMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNY
CC	ATOM   SMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNY
CC	       **************************************************
CC	SEQRES LREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVV
CC	ATOM   LREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVV
CC	       **************************************************
CC	SEQRES KVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGV
CC	ATOM   KVSDF------------------FPVRWSPPEVLMYSKFSSKSDIWAFGV
CC	       *****                  ***************************
CC	SEQRES LMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWH
CC	ATOM   LMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWH
CC	       **************************************************
CC	SEQRES EKADERPTFKILLSNILDVMDEES
CC	ATOM   EKADERPTFKILLSNILDVMDEES
CC	       ************************
SQ	SEQUENCE	274 AA;      MW;         CN;
	GTAGLGYGSW EIDPKDLTFL KELGTGQFGV VKYGKWRGQY DVAIKMIKEG SMSEDEFIEE
	AKVMMNLSHE KLVQLYGVCT KQRPIFIITE YMANGCLLNY LREMRHRFQT QQLLEMCKDV
	CEAMEYLESK QFLHRDLAAR NCLVNDQGVV KVSDFGLSRY VLDDEYTSSV GSKFPVRWSP
	PEVLMYSKFS SKSDIWAFGV LMWEIYSLGK MPYERFTNSE TAEHIAQGLR LYRPHLASEK
	VYTIMYSCWH EKADERPTFK ILLSNILDVM DEES
//