ID	3PIZA	STANDARD;	PRT;	274	AA.
DT	CONVERTED FROM PDB (SEQRES) 3PIZ
DE	Tyrosine-protein kinase BTK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.210
CC	R-Factor	0.228
FT	#HET	23	 408 	LEU	A	1	1 	03C	A	A	4
FT	#HET	31	 416 	VAL	A	1	1 	03C	A	S	2
FT	#HET	43	 428 	ALA	A	1	1 	03C	A	A	8
FT	#HET	44	 429 	ILE	A	1	1 	03C	A	B	1
FT	#HET	45	 430 	LYS	A	1	1 	03C	A	A	2
FT	#HET	60	 445 	GLU	A	1	1 	03C	A	S	3
FT	#HET	73	 458 	VAL	A	1	1 	03C	A	S	1
FT	#HET	87	 472 	ILE	A	1	1 	03C	A	S	1
FT	#HET	89	 474 	THR	A	1	1 	03C	A	S	8
FT	#HET	90	 475 	GLU	A	1	1 	03C	A	B	2
FT	#HET	91	 476 	TYR	A	1	1 	03C	A	A	5
FT	#HET	92	 477 	MET	A	1	1 	03C	A	A	10
FT	#HET	95	 480 	GLY	A	1	1 	03C	A	B	2
FT	#HET	96	 481 	CYS	A	1	1 	03C	A	B	1
FT	#HET	143	 528 	LEU	A	1	1 	03C	A	S	6
FT	#HET	153	 538 	SER	A	1	1 	03C	A	S	2
FT	DISORDER	1	5
FT	DISORDER	26	28
FT	DISORDER	48	52
FT	DISORDER	158	173
CC	SEQUENCE	245 AA (ATOM);
CC	GYGSWEIDPK DLTFLKELGT GVVKYGKWRG QYDVAIKMIS EDEFIEEAKV MMNLSHEKLV
CC	QLYGVCTKQR PIFIITEYMA NGCLLNYLRE MRHRFQTQQL LEMCKDVCEA MEYLESKQFL
CC	HRDLAARNCL VNDQGVVKVS DFGLFPVRWS PPEVLMYSKF SSKSDIWAFG VLMWEIYSLG
CC	KMPYERFTNS ETAEHIAQGL RLYRPHLASE KVYTIMYSCW HEKADERPTF KILLSNILDV
CC	MDEES
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGKWRGQYDVAIKMIKEG
CC	ATOM   -----GYGSWEIDPKDLTFLKELGT---GVVKYGKWRGQYDVAIKMI---
CC	            ********************   *******************   
CC	SEQRES SMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNY
CC	ATOM   --SEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANGCLLNY
CC	         ************************************************
CC	SEQRES LREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVV
CC	ATOM   LREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVV
CC	       **************************************************
CC	SEQRES KVSDFGLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGV
CC	ATOM   KVSDFGL----------------FPVRWSPPEVLMYSKFSSKSDIWAFGV
CC	       *******                ***************************
CC	SEQRES LMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWH
CC	ATOM   LMWEIYSLGKMPYERFTNSETAEHIAQGLRLYRPHLASEKVYTIMYSCWH
CC	       **************************************************
CC	SEQRES EKADERPTFKILLSNILDVMDEES
CC	ATOM   EKADERPTFKILLSNILDVMDEES
CC	       ************************
SQ	SEQUENCE	274 AA;      MW;         CN;
	GTAGLGYGSW EIDPKDLTFL KELGTGQFGV VKYGKWRGQY DVAIKMIKEG SMSEDEFIEE
	AKVMMNLSHE KLVQLYGVCT KQRPIFIITE YMANGCLLNY LREMRHRFQT QQLLEMCKDV
	CEAMEYLESK QFLHRDLAAR NCLVNDQGVV KVSDFGLSRY VLDDEYTSSV GSKFPVRWSP
	PEVLMYSKFS SKSDIWAFGV LMWEIYSLGK MPYERFTNSE TAEHIAQGLR LYRPHLASEK
	VYTIMYSCWH EKADERPTFK ILLSNILDVM DEES
//