ID	3OG7A	STANDARD;	PRT;	289	AA.
DT	CONVERTED FROM PDB (SEQRES) 3OG7
DE	AKAP9-BRAF fusion protein
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.214
FT	#SUB	19	 450 	TRP	A	75	 506 	ARG	B	Protein	S	2
FT	#SUB	19	 450 	TRP	A	76	 507 	LYS	B	Protein	S	6
FT	#SUB	19	 450 	TRP	A	77	 508 	THR	B	Protein	S	3
FT	#SUB	19	 450 	TRP	A	78	 509 	ARG	B	Protein	S	9
FT	#SUB	19	 450 	TRP	A	135	 566 	TYR	B	Protein	S	2
FT	#SUB	19	 450 	TRP	A	139	 570 	LYS	B	Protein	S	2
FT	#SUB	44	 475 	LYS	A	284	 715 	GLU	B	Protein	S	1
FT	#SUB	45	 476 	TRP	A	135	 566 	TYR	B	Protein	S	2
FT	#SUB	46	 477 	HIS	A	79	 510 	HIS	B	Protein	B	3
FT	#SUB	46	 477 	HIS	A	131	 562 	ARG	B	Protein	B	3
FT	#SUB	46	 477 	HIS	A	134	 565 	ASP	B	Protein	A	7
FT	#SUB	46	 477 	HIS	A	135	 566 	TYR	B	Protein	S	2
FT	#SUB	46	 477 	HIS	A	138	 569 	ALA	B	Protein	S	2
FT	#SUB	47	 478 	GLY	A	131	 562 	ARG	B	Protein	B	2
FT	#SUB	48	 479 	ASP	A	131	 562 	ARG	B	Protein	A	2
FT	#SUB	75	 506 	ARG	A	19	 450 	TRP	B	Protein	B	2
FT	#SUB	75	 506 	ARG	A	75	 506 	ARG	B	Protein	S	2
FT	#SUB	75	 506 	ARG	A	78	 509 	ARG	B	Protein	B	3
FT	#SUB	76	 507 	LYS	A	19	 450 	TRP	B	Protein	B	3
FT	#SUB	77	 508 	THR	A	19	 450 	TRP	B	Protein	B	1
FT	#SUB	77	 508 	THR	A	78	 509 	ARG	B	Protein	B	5
FT	#SUB	78	 509 	ARG	A	19	 450 	TRP	B	Protein	S	11
FT	#SUB	78	 509 	ARG	A	74	 505 	LEU	B	Protein	S	1
FT	#SUB	78	 509 	ARG	A	75	 506 	ARG	B	Protein	S	3
FT	#SUB	78	 509 	ARG	A	77	 508 	THR	B	Protein	S	5
FT	#SUB	78	 509 	ARG	A	78	 509 	ARG	B	Protein	S	3
FT	#SUB	78	 509 	ARG	A	84	 515 	LEU	B	Protein	S	1
FT	#SUB	78	 509 	ARG	A	85	 516 	PHE	B	Protein	S	13
FT	#SUB	78	 509 	ARG	A	86	 517 	MET	B	Protein	B	3
FT	#SUB	79	 510 	HIS	A	46	 477 	HIS	B	Protein	S	4
FT	#SUB	79	 510 	HIS	A	84	 515 	LEU	B	Protein	B	4
FT	#SUB	79	 510 	HIS	A	86	 517 	MET	B	Protein	S	1
FT	#SUB	80	 511 	VAL	A	84	 515 	LEU	B	Protein	B	1
FT	#SUB	84	 515 	LEU	A	78	 509 	ARG	B	Protein	S	2
FT	#SUB	84	 515 	LEU	A	79	 510 	HIS	B	Protein	S	4
FT	#SUB	84	 515 	LEU	A	80	 511 	VAL	B	Protein	S	1
FT	#SUB	85	 516 	PHE	A	78	 509 	ARG	B	Protein	A	9
FT	#SUB	86	 517 	MET	A	78	 509 	ARG	B	Protein	S	4
FT	#SUB	86	 517 	MET	A	79	 510 	HIS	B	Protein	S	1
FT	#SUB	99	 530 	GLN	A	80	 511 	VAL	B	Protein	S	1
FT	#SUB	131	 562 	ARG	A	44	 475 	LYS	B	Protein	S	1
FT	#SUB	131	 562 	ARG	A	46	 477 	HIS	B	Protein	A	4
FT	#SUB	131	 562 	ARG	A	47	 478 	GLY	B	Protein	S	3
FT	#SUB	131	 562 	ARG	A	48	 479 	ASP	B	Protein	S	1
FT	#SUB	134	 565 	ASP	A	46	 477 	HIS	B	Protein	A	4
FT	#SUB	135	 566 	TYR	A	19	 450 	TRP	B	Protein	S	1
FT	#SUB	135	 566 	TYR	A	45	 476 	TRP	B	Protein	S	2
FT	#SUB	138	 569 	ALA	A	46	 477 	HIS	B	Protein	S	2
FT	#SUB	139	 570 	LYS	A	19	 450 	TRP	B	Protein	S	2
FT	#SUB	155	 586 	GLU	A	155	 586 	GLU	B	Protein	S	1
FT	#SUB	155	 586 	GLU	A	157	 588 	ASN	B	Protein	S	3
FT	#SUB	155	 586 	GLU	A	158	 589 	THR	B	Protein	S	1
FT	#SUB	158	 589 	THR	A	155	 586 	GLU	B	Protein	S	1
FT	#SUB	284	 715 	GLU	A	44	 475 	LYS	B	Protein	S	2
FT	#HET	32	 463 	ILE	A	1	1 	032	A	S	2
FT	#HET	40	 471 	VAL	A	1	1 	032	A	S	2
FT	#HET	50	 481 	ALA	A	1	1 	032	A	A	6
FT	#HET	52	 483 	LYS	A	1	1 	032	A	A	7
FT	#HET	74	 505 	LEU	A	1	1 	032	A	S	4
FT	#HET	83	 514 	LEU	A	1	1 	032	A	A	10
FT	#HET	96	 527 	ILE	A	1	1 	032	A	A	2
FT	#HET	98	 529 	THR	A	1	1 	032	A	S	6
FT	#HET	99	 530 	GLN	A	1	1 	032	A	B	2
FT	#HET	100	 531 	TRP	A	1	1 	032	A	S	7
FT	#HET	101	 532 	CYS	A	1	1 	032	A	A	8
FT	#HET	152	 583 	PHE	A	1	1 	032	A	S	5
FT	#HET	162	 593 	GLY	A	1	1 	032	A	B	2
FT	#HET	163	 594 	ASP	A	1	1 	032	A	B	9
FT	#HET	164	 595 	PHE	A	1	1 	032	A	A	6
FT	#HET	165	 596 	GLY	A	1	1 	032	A	B	3
FT	DISORDER	1	17
FT	DISORDER	114	116
FT	DISORDER	166	183
FT	DISORDER	196	199
CC	SEQUENCE	247 AA (ATOM);
CC	DWEIPDGQIT VGQRIGSGSF GTVYKGKWHG DVAVKMLNVT APTPQQLQAF KNEVGVLRKT
CC	RHVNILLFMG YSTAPQLAIV TQWCEGSSLY HHLHASFEMK KLIDIARQTA RGMDYLHAKS
CC	IIHRDLKSNN IFLHEDNTVK IGDFGGSILW MAPEVIRNPY SFQSDVYAFG IVLYELMTGQ
CC	LPYSNINNRD QIIEMVGRGS LSPDLSKVRS NCPKRMKRLM AECLKKKRDE RPSFPRILAE
CC	IEELARE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MKKGHHHHHHGSRDAADDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
CC	ATOM   -----------------DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
CC	                        *********************************
CC	SEQRES VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQW
CC	ATOM   VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQW
CC	       **************************************************
CC	SEQRES CEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNN
CC	ATOM   CEGSSLYHHLHAS---FEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNN
CC	       *************   **********************************
CC	SEQRES IFLHEDNTVKIGDFGLATEKSRWSGSHQFEQLSGSILWMAPEVIRMQDSN
CC	ATOM   IFLHEDNTVKIGDFG------------------GSILWMAPEVIR----N
CC	       ***************                  ************    *
CC	SEQRES PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKV
CC	ATOM   PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKV
CC	       **************************************************
CC	SEQRES RSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE
CC	ATOM   RSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE
CC	       ***************************************
SQ	SEQUENCE	289 AA;      MW;         CN;
	MKKGHHHHHH GSRDAADDWE IPDGQITVGQ RIGSGSFGTV YKGKWHGDVA VKMLNVTAPT
	PQQLQAFKNE VGVLRKTRHV NILLFMGYST APQLAIVTQW CEGSSLYHHL HASETKFEMK
	KLIDIARQTA RGMDYLHAKS IIHRDLKSNN IFLHEDNTVK IGDFGLATEK SRWSGSHQFE
	QLSGSILWMA PEVIRMQDSN PYSFQSDVYA FGIVLYELMT GQLPYSNINN RDQIIEMVGR
	GSLSPDLSKV RSNCPKRMKR LMAECLKKKR DERPSFPRIL AEIEELARE
//
ID	3OG7B	STANDARD;	PRT;	289	AA.
DT	CONVERTED FROM PDB (SEQRES) 3OG7
DE	AKAP9-BRAF fusion protein
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.214
FT	#SUB	19	 450 	TRP	B	75	 506 	ARG	A	Protein	S	2
FT	#SUB	19	 450 	TRP	B	76	 507 	LYS	A	Protein	S	3
FT	#SUB	19	 450 	TRP	B	77	 508 	THR	A	Protein	S	1
FT	#SUB	19	 450 	TRP	B	78	 509 	ARG	A	Protein	S	11
FT	#SUB	19	 450 	TRP	B	135	 566 	TYR	A	Protein	S	1
FT	#SUB	19	 450 	TRP	B	139	 570 	LYS	A	Protein	S	2
FT	#SUB	44	 475 	LYS	B	131	 562 	ARG	A	Protein	S	1
FT	#SUB	44	 475 	LYS	B	284	 715 	GLU	A	Protein	S	2
FT	#SUB	45	 476 	TRP	B	135	 566 	TYR	A	Protein	S	2
FT	#SUB	46	 477 	HIS	B	79	 510 	HIS	A	Protein	B	4
FT	#SUB	46	 477 	HIS	B	131	 562 	ARG	A	Protein	B	4
FT	#SUB	46	 477 	HIS	B	134	 565 	ASP	A	Protein	S	4
FT	#SUB	46	 477 	HIS	B	138	 569 	ALA	A	Protein	S	2
FT	#SUB	47	 478 	GLY	B	131	 562 	ARG	A	Protein	B	3
FT	#SUB	48	 479 	ASP	B	131	 562 	ARG	A	Protein	S	1
FT	#SUB	74	 505 	LEU	B	78	 509 	ARG	A	Protein	B	1
FT	#SUB	75	 506 	ARG	B	19	 450 	TRP	A	Protein	B	2
FT	#SUB	75	 506 	ARG	B	75	 506 	ARG	A	Protein	S	2
FT	#SUB	75	 506 	ARG	B	78	 509 	ARG	A	Protein	B	3
FT	#SUB	76	 507 	LYS	B	19	 450 	TRP	A	Protein	B	6
FT	#SUB	77	 508 	THR	B	19	 450 	TRP	A	Protein	B	3
FT	#SUB	77	 508 	THR	B	78	 509 	ARG	A	Protein	B	5
FT	#SUB	78	 509 	ARG	B	19	 450 	TRP	A	Protein	A	9
FT	#SUB	78	 509 	ARG	B	75	 506 	ARG	A	Protein	S	3
FT	#SUB	78	 509 	ARG	B	77	 508 	THR	A	Protein	S	5
FT	#SUB	78	 509 	ARG	B	78	 509 	ARG	A	Protein	S	3
FT	#SUB	78	 509 	ARG	B	84	 515 	LEU	A	Protein	A	2
FT	#SUB	78	 509 	ARG	B	85	 516 	PHE	A	Protein	S	9
FT	#SUB	78	 509 	ARG	B	86	 517 	MET	A	Protein	B	4
FT	#SUB	79	 510 	HIS	B	46	 477 	HIS	A	Protein	S	3
FT	#SUB	79	 510 	HIS	B	84	 515 	LEU	A	Protein	B	4
FT	#SUB	79	 510 	HIS	B	86	 517 	MET	A	Protein	S	1
FT	#SUB	80	 511 	VAL	B	84	 515 	LEU	A	Protein	B	1
FT	#SUB	80	 511 	VAL	B	99	 530 	GLN	A	Protein	S	1
FT	#SUB	84	 515 	LEU	B	78	 509 	ARG	A	Protein	S	1
FT	#SUB	84	 515 	LEU	B	79	 510 	HIS	A	Protein	S	4
FT	#SUB	84	 515 	LEU	B	80	 511 	VAL	A	Protein	S	1
FT	#SUB	85	 516 	PHE	B	78	 509 	ARG	A	Protein	A	13
FT	#SUB	86	 517 	MET	B	78	 509 	ARG	A	Protein	S	3
FT	#SUB	86	 517 	MET	B	79	 510 	HIS	A	Protein	S	1
FT	#SUB	131	 562 	ARG	B	46	 477 	HIS	A	Protein	A	3
FT	#SUB	131	 562 	ARG	B	47	 478 	GLY	A	Protein	S	2
FT	#SUB	131	 562 	ARG	B	48	 479 	ASP	A	Protein	S	2
FT	#SUB	134	 565 	ASP	B	46	 477 	HIS	A	Protein	A	7
FT	#SUB	135	 566 	TYR	B	19	 450 	TRP	A	Protein	S	2
FT	#SUB	135	 566 	TYR	B	45	 476 	TRP	A	Protein	S	2
FT	#SUB	135	 566 	TYR	B	46	 477 	HIS	A	Protein	A	2
FT	#SUB	138	 569 	ALA	B	46	 477 	HIS	A	Protein	S	2
FT	#SUB	139	 570 	LYS	B	19	 450 	TRP	A	Protein	S	2
FT	#SUB	155	 586 	GLU	B	155	 586 	GLU	A	Protein	S	1
FT	#SUB	155	 586 	GLU	B	158	 589 	THR	A	Protein	S	1
FT	#SUB	157	 588 	ASN	B	155	 586 	GLU	A	Protein	S	3
FT	#SUB	158	 589 	THR	B	155	 586 	GLU	A	Protein	S	1
FT	#SUB	284	 715 	GLU	B	44	 475 	LYS	A	Protein	S	1
FT	DISORDER	1	17
FT	DISORDER	170	183
FT	DISORDER	196	199
CC	SEQUENCE	254 AA (ATOM);
CC	DWEIPDGQIT VGQRIGSGSF GTVYKGKWHG DVAVKMLNVT APTPQQLQAF KNEVGVLRKT
CC	RHVNILLFMG YSTAPQLAIV TQWCEGSSLY HHLHASETKF EMKKLIDIAR QTARGMDYLH
CC	AKSIIHRDLK SNNIFLHEDN TVKIGDFGLA TEGSILWMAP EVIRNPYSFQ SDVYAFGIVL
CC	YELMTGQLPY SNINNRDQII EMVGRGSLSP DLSKVRSNCP KRMKRLMAEC LKKKRDERPS
CC	FPRILAEIEE LARE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MKKGHHHHHHGSRDAADDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
CC	ATOM   -----------------DWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVA
CC	                        *********************************
CC	SEQRES VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQW
CC	ATOM   VKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTAPQLAIVTQW
CC	       **************************************************
CC	SEQRES CEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNN
CC	ATOM   CEGSSLYHHLHASETKFEMKKLIDIARQTARGMDYLHAKSIIHRDLKSNN
CC	       **************************************************
CC	SEQRES IFLHEDNTVKIGDFGLATEKSRWSGSHQFEQLSGSILWMAPEVIRMQDSN
CC	ATOM   IFLHEDNTVKIGDFGLATE--------------GSILWMAPEVIR----N
CC	       *******************              ************    *
CC	SEQRES PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKV
CC	ATOM   PYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIEMVGRGSLSPDLSKV
CC	       **************************************************
CC	SEQRES RSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE
CC	ATOM   RSNCPKRMKRLMAECLKKKRDERPSFPRILAEIEELARE
CC	       ***************************************
SQ	SEQUENCE	289 AA;      MW;         CN;
	MKKGHHHHHH GSRDAADDWE IPDGQITVGQ RIGSGSFGTV YKGKWHGDVA VKMLNVTAPT
	PQQLQAFKNE VGVLRKTRHV NILLFMGYST APQLAIVTQW CEGSSLYHHL HASETKFEMK
	KLIDIARQTA RGMDYLHAKS IIHRDLKSNN IFLHEDNTVK IGDFGLATEK SRWSGSHQFE
	QLSGSILWMA PEVIRMQDSN PYSFQSDVYA FGIVLYELMT GQLPYSNINN RDQIIEMVGR
	GSLSPDLSKV RSNCPKRMKR LMAECLKKKR DERPSFPRIL AEIEELARE
//