ID	3ME6A	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3ME6
DE	Cytochrome P450 2B4
OS	Oryctolagus cuniculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.100
CC	R-Factor	0.181
FT	#SUB	298	 317 	TYR	A	398	 417 	ASN	B	Protein	S	4
FT	#SUB	300	 319 	HIS	A	397	 416 	ALA	B	Protein	S	1
FT	#SUB	300	 319 	HIS	A	398	 417 	ASN	B	Protein	S	8
FT	#SUB	382	 401 	TYR	A	384	 403 	GLU	B	Protein	B	3
FT	#SUB	383	 402 	PHE	A	384	 403 	GLU	B	Protein	B	3
FT	#SUB	384	 403 	GLU	A	382	 401 	TYR	B	Protein	S	4
FT	#SUB	384	 403 	GLU	A	383	 402 	PHE	B	Protein	S	3
FT	#SUB	384	 403 	GLU	A	384	 403 	GLU	B	Protein	A	15
FT	#SUB	384	 403 	GLU	A	393	 412 	HIS	B	Protein	S	4
FT	#SUB	384	 403 	GLU	A	402	 421 	LYS	B	Protein	S	1
FT	#SUB	385	 404 	THR	A	402	 421 	LYS	B	Protein	S	2
FT	#SUB	389	 408 	PHE	A	397	 416 	ALA	B	Protein	B	1
FT	#SUB	390	 409 	ASN	A	395	 414 	LEU	B	Protein	S	1
FT	#SUB	390	 409 	ASN	A	396	 415 	ASP	B	Protein	S	2
FT	#SUB	390	 409 	ASN	A	397	 416 	ALA	B	Protein	S	3
FT	#SUB	391	 410 	PRO	A	397	 416 	ALA	B	Protein	S	1
FT	#SUB	393	 412 	HIS	A	384	 403 	GLU	B	Protein	A	5
FT	#SUB	395	 414 	LEU	A	390	 409 	ASN	B	Protein	B	1
FT	#SUB	396	 415 	ASP	A	390	 409 	ASN	B	Protein	B	1
FT	#SUB	397	 416 	ALA	A	298	 317 	TYR	B	Protein	S	2
FT	#SUB	397	 416 	ALA	A	300	 319 	HIS	B	Protein	B	1
FT	#SUB	397	 416 	ALA	A	301	 320 	VAL	B	Protein	B	1
FT	#SUB	397	 416 	ALA	A	389	 408 	PHE	B	Protein	A	2
FT	#SUB	397	 416 	ALA	A	390	 409 	ASN	B	Protein	B	4
FT	#SUB	398	 417 	ASN	A	298	 317 	TYR	B	Protein	S	4
FT	#SUB	398	 417 	ASN	A	300	 319 	HIS	B	Protein	A	8
FT	#SUB	402	 421 	LYS	A	385	 404 	THR	B	Protein	S	1
FT	#SUB	402	 421 	LYS	A	390	 409 	ASN	B	Protein	S	1
FT	#SUB	125	 144 	GLU	A	132	 151 	ARG	C	Protein	S	1
FT	#SUB	132	 151 	ARG	A	125	 144 	GLU	C	Protein	S	1
FT	#SUB	316	 335 	HIS	A	322	 341 	ASP	C	Protein	A	4
FT	#SUB	317	 336 	ARG	A	317	 336 	ARG	C	Protein	S	12
FT	#SUB	317	 336 	ARG	A	320	 339 	ALA	C	Protein	S	1
FT	#SUB	320	 339 	ALA	A	317	 336 	ARG	C	Protein	S	1
FT	#SUB	322	 341 	ASP	A	317	 336 	ARG	C	Protein	S	2
FT	#HET	79	  98 	ARG	A	1	500 	HEM	A	S	9
FT	#HET	85	 104 	VAL	A	2	501 	CGE	A	S	1
FT	#HET	89	 108 	PHE	A	2	501 	CGE	A	S	2
FT	#HET	95	 114 	ILE	A	1	500 	HEM	A	A	3
FT	#HET	102	 121 	TRP	A	1	500 	HEM	A	S	5
FT	#HET	106	 125 	ARG	A	1	500 	HEM	A	S	5
FT	#HET	187	 206 	PHE	A	2	501 	CGE	A	S	5
FT	#HET	190	 209 	ILE	A	2	501 	CGE	A	S	1
FT	#HET	276	 295 	LEU	A	1	500 	HEM	A	S	2
FT	#HET	278	 297 	PHE	A	2	501 	CGE	A	A	24
FT	#HET	279	 298 	ALA	A	1	500 	HEM	A	A	7
FT	#HET	279	 298 	ALA	A	2	501 	CGE	A	A	10
FT	#HET	280	 299 	GLY	A	1	500 	HEM	A	B	7
FT	#HET	283	 302 	THR	A	1	500 	HEM	A	A	5
FT	#HET	283	 302 	THR	A	2	501 	CGE	A	S	3
FT	#HET	284	 303 	THR	A	1	500 	HEM	A	A	4
FT	#HET	338	 357 	GLN	A	1	500 	HEM	A	S	1
FT	#HET	344	 363 	ILE	A	1	500 	HEM	A	S	4
FT	#HET	344	 363 	ILE	A	2	501 	CGE	A	S	1
FT	#HET	348	 367 	VAL	A	1	500 	HEM	A	A	3
FT	#HET	348	 367 	VAL	A	2	501 	CGE	A	S	1
FT	#HET	350	 369 	HIS	A	1	500 	HEM	A	S	6
FT	#HET	373	 392 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	409	 428 	PRO	A	1	500 	HEM	A	B	2
FT	#HET	410	 429 	PHE	A	1	500 	HEM	A	A	10
FT	#HET	411	 430 	SER	A	1	500 	HEM	A	A	8
FT	#HET	415	 434 	ARG	A	1	500 	HEM	A	A	13
FT	#HET	417	 436 	CYS	A	1	500 	HEM	A	A	17
FT	#HET	419	 438 	GLY	A	1	500 	HEM	A	B	5
FT	#HET	422	 441 	ILE	A	1	500 	HEM	A	S	1
FT	#HET	423	 442 	ALA	A	1	500 	HEM	A	S	3
FT	#HET	458	 477 	VAL	A	2	501 	CGE	A	A	4
FT	DISORDER	1	8
FT	DISORDER	474	476
CC	SEQUENCE	465 AA (ATOM);
CC	GKLPPGPSPL PVLGNLLQMD RKGLLRSFLR LREKYGDVFT VYLGSRPVVV LCGTDAIREA
CC	LVDQAEAFSG RGKIAVVDPI FQGYGVIFAN GERWRALRRF SLATMRDFGM GKRSVEERIQ
CC	EEARCLVEEL RKSKGALLDN TLLFHSITSN IICSIVFGKR FDYKDPVFLR LLDLFFQSFS
CC	LISSFSSQVF ELFSGFLKYF PGTHRQIYRN LQEINTFIGQ SVEKHRATLD PSNPRDFIDV
CC	YLLRMEKDKS DPSSEFHHQN LILTVLSLFF AGTETTSTTL RYGFLLMLKY PHVTERVQKE
CC	IEQVIGSHRP PALDDRAKMP YTDAVIHEIQ RLGDLIPFGV PHTVTKDTQF RGYVIPKNTE
CC	VFPVLSSALH DPRYFETPNT FNPGHFLDAN GALKRNEGFM PFSLGKRICL GEGIARTELF
CC	LFFTTILQNF SIASPVPPED IDLTPRESGV GNVPPSYQIR FLARH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	ATOM   --------GKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	               ******************************************
CC	SEQRES LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	ATOM   LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	       **************************************************
CC	SEQRES RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	ATOM   RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	       **************************************************
CC	SEQRES LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	ATOM   LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	       **************************************************
CC	SEQRES FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	ATOM   FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	       **************************************************
CC	SEQRES LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	ATOM   VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	       **************************************************
CC	SEQRES TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	ATOM   TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	       **************************************************
CC	SEQRES LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	ATOM   LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	       **************************************************
CC	SEQRES LTPRESGVGNVPPSYQIRFLARHHHH
CC	ATOM   LTPRESGVGNVPPSYQIRFLARH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPSPLPV LGNLLQMDRK GLLRSFLRLR EKYGDVFTVY LGSRPVVVLC
	GTDAIREALV DQAEAFSGRG KIAVVDPIFQ GYGVIFANGE RWRALRRFSL ATMRDFGMGK
	RSVEERIQEE ARCLVEELRK SKGALLDNTL LFHSITSNII CSIVFGKRFD YKDPVFLRLL
	DLFFQSFSLI SSFSSQVFEL FSGFLKYFPG THRQIYRNLQ EINTFIGQSV EKHRATLDPS
	NPRDFIDVYL LRMEKDKSDP SSEFHHQNLI LTVLSLFFAG TETTSTTLRY GFLLMLKYPH
	VTERVQKEIE QVIGSHRPPA LDDRAKMPYT DAVIHEIQRL GDLIPFGVPH TVTKDTQFRG
	YVIPKNTEVF PVLSSALHDP RYFETPNTFN PGHFLDANGA LKRNEGFMPF SLGKRICLGE
	GIARTELFLF FTTILQNFSI ASPVPPEDID LTPRESGVGN VPPSYQIRFL ARHHHH
//
ID	3ME6B	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3ME6
DE	Cytochrome P450 2B4
OS	Oryctolagus cuniculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.100
CC	R-Factor	0.181
FT	#SUB	298	 317 	TYR	B	397	 416 	ALA	A	Protein	S	2
FT	#SUB	298	 317 	TYR	B	398	 417 	ASN	A	Protein	S	4
FT	#SUB	300	 319 	HIS	B	397	 416 	ALA	A	Protein	S	1
FT	#SUB	300	 319 	HIS	B	398	 417 	ASN	A	Protein	S	8
FT	#SUB	301	 320 	VAL	B	397	 416 	ALA	A	Protein	S	1
FT	#SUB	382	 401 	TYR	B	384	 403 	GLU	A	Protein	B	4
FT	#SUB	383	 402 	PHE	B	384	 403 	GLU	A	Protein	B	3
FT	#SUB	384	 403 	GLU	B	382	 401 	TYR	A	Protein	S	3
FT	#SUB	384	 403 	GLU	B	383	 402 	PHE	A	Protein	S	3
FT	#SUB	384	 403 	GLU	B	384	 403 	GLU	A	Protein	A	15
FT	#SUB	384	 403 	GLU	B	393	 412 	HIS	A	Protein	S	5
FT	#SUB	385	 404 	THR	B	402	 421 	LYS	A	Protein	S	1
FT	#SUB	389	 408 	PHE	B	397	 416 	ALA	A	Protein	B	2
FT	#SUB	390	 409 	ASN	B	395	 414 	LEU	A	Protein	S	1
FT	#SUB	390	 409 	ASN	B	396	 415 	ASP	A	Protein	S	1
FT	#SUB	390	 409 	ASN	B	397	 416 	ALA	A	Protein	S	4
FT	#SUB	390	 409 	ASN	B	402	 421 	LYS	A	Protein	S	1
FT	#SUB	393	 412 	HIS	B	384	 403 	GLU	A	Protein	S	4
FT	#SUB	395	 414 	LEU	B	390	 409 	ASN	A	Protein	B	1
FT	#SUB	396	 415 	ASP	B	390	 409 	ASN	A	Protein	B	2
FT	#SUB	397	 416 	ALA	B	300	 319 	HIS	A	Protein	B	1
FT	#SUB	397	 416 	ALA	B	389	 408 	PHE	A	Protein	S	1
FT	#SUB	397	 416 	ALA	B	390	 409 	ASN	A	Protein	B	3
FT	#SUB	397	 416 	ALA	B	391	 410 	PRO	A	Protein	S	1
FT	#SUB	398	 417 	ASN	B	298	 317 	TYR	A	Protein	S	4
FT	#SUB	398	 417 	ASN	B	300	 319 	HIS	A	Protein	A	8
FT	#SUB	402	 421 	LYS	B	384	 403 	GLU	A	Protein	S	1
FT	#SUB	402	 421 	LYS	B	385	 404 	THR	A	Protein	S	2
FT	#SUB	142	 161 	LYS	B	144	 163 	ALA	D	Protein	B	2
FT	#SUB	142	 161 	LYS	B	145	 164 	LEU	D	Protein	A	2
FT	#SUB	142	 161 	LYS	B	468	 487 	ARG	D	Protein	B	3
FT	#SUB	143	 162 	GLY	B	468	 487 	ARG	D	Protein	B	1
FT	#SUB	144	 163 	ALA	B	142	 161 	LYS	D	Protein	B	2
FT	#SUB	144	 163 	ALA	B	144	 163 	ALA	D	Protein	A	2
FT	#SUB	145	 164 	LEU	B	142	 161 	LYS	D	Protein	B	1
FT	#SUB	468	 487 	ARG	B	142	 161 	LYS	D	Protein	S	3
FT	#SUB	468	 487 	ARG	B	143	 162 	GLY	D	Protein	S	1
FT	#SUB	468	 487 	ARG	B	470	 489 	LEU	D	Protein	S	4
FT	#SUB	470	 489 	LEU	B	468	 487 	ARG	D	Protein	S	4
FT	#HET	79	  98 	ARG	B	3	500 	HEM	B	S	9
FT	#HET	89	 108 	PHE	B	4	501 	CGE	B	S	2
FT	#HET	95	 114 	ILE	B	3	500 	HEM	B	A	3
FT	#HET	102	 121 	TRP	B	3	500 	HEM	B	S	5
FT	#HET	106	 125 	ARG	B	3	500 	HEM	B	S	4
FT	#HET	187	 206 	PHE	B	4	501 	CGE	B	S	5
FT	#HET	190	 209 	ILE	B	4	501 	CGE	B	S	1
FT	#HET	276	 295 	LEU	B	3	500 	HEM	B	S	1
FT	#HET	278	 297 	PHE	B	4	501 	CGE	B	A	16
FT	#HET	279	 298 	ALA	B	3	500 	HEM	B	A	6
FT	#HET	279	 298 	ALA	B	4	501 	CGE	B	A	9
FT	#HET	280	 299 	GLY	B	3	500 	HEM	B	B	9
FT	#HET	283	 302 	THR	B	3	500 	HEM	B	A	10
FT	#HET	283	 302 	THR	B	4	501 	CGE	B	S	3
FT	#HET	284	 303 	THR	B	3	500 	HEM	B	A	2
FT	#HET	287	 306 	THR	B	3	500 	HEM	B	S	1
FT	#HET	338	 357 	GLN	B	3	500 	HEM	B	S	1
FT	#HET	344	 363 	ILE	B	3	500 	HEM	B	S	4
FT	#HET	348	 367 	VAL	B	3	500 	HEM	B	S	2
FT	#HET	348	 367 	VAL	B	4	501 	CGE	B	S	1
FT	#HET	350	 369 	HIS	B	3	500 	HEM	B	S	7
FT	#HET	373	 392 	LEU	B	3	500 	HEM	B	S	1
FT	#HET	409	 428 	PRO	B	3	500 	HEM	B	B	3
FT	#HET	410	 429 	PHE	B	3	500 	HEM	B	A	10
FT	#HET	411	 430 	SER	B	3	500 	HEM	B	A	7
FT	#HET	415	 434 	ARG	B	3	500 	HEM	B	A	16
FT	#HET	417	 436 	CYS	B	3	500 	HEM	B	A	17
FT	#HET	418	 437 	LEU	B	3	500 	HEM	B	S	1
FT	#HET	419	 438 	GLY	B	3	500 	HEM	B	B	4
FT	#HET	423	 442 	ALA	B	3	500 	HEM	B	S	1
FT	#HET	458	 477 	VAL	B	4	501 	CGE	B	A	3
FT	DISORDER	1	8
FT	DISORDER	474	476
CC	SEQUENCE	465 AA (ATOM);
CC	GKLPPGPSPL PVLGNLLQMD RKGLLRSFLR LREKYGDVFT VYLGSRPVVV LCGTDAIREA
CC	LVDQAEAFSG RGKIAVVDPI FQGYGVIFAN GERWRALRRF SLATMRDFGM GKRSVEERIQ
CC	EEARCLVEEL RKSKGALLDN TLLFHSITSN IICSIVFGKR FDYKDPVFLR LLDLFFQSFS
CC	LISSFSSQVF ELFSGFLKYF PGTHRQIYRN LQEINTFIGQ SVEKHRATLD PSNPRDFIDV
CC	YLLRMEKDKS DPSSEFHHQN LILTVLSLFF AGTETTSTTL RYGFLLMLKY PHVTERVQKE
CC	IEQVIGSHRP PALDDRAKMP YTDAVIHEIQ RLGDLIPFGV PHTVTKDTQF RGYVIPKNTE
CC	VFPVLSSALH DPRYFETPNT FNPGHFLDAN GALKRNEGFM PFSLGKRICL GEGIARTELF
CC	LFFTTILQNF SIASPVPPED IDLTPRESGV GNVPPSYQIR FLARH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	ATOM   --------GKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	               ******************************************
CC	SEQRES LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	ATOM   LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	       **************************************************
CC	SEQRES RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	ATOM   RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	       **************************************************
CC	SEQRES LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	ATOM   LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	       **************************************************
CC	SEQRES FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	ATOM   FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	       **************************************************
CC	SEQRES LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	ATOM   VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	       **************************************************
CC	SEQRES TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	ATOM   TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	       **************************************************
CC	SEQRES LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	ATOM   LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	       **************************************************
CC	SEQRES LTPRESGVGNVPPSYQIRFLARHHHH
CC	ATOM   LTPRESGVGNVPPSYQIRFLARH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPSPLPV LGNLLQMDRK GLLRSFLRLR EKYGDVFTVY LGSRPVVVLC
	GTDAIREALV DQAEAFSGRG KIAVVDPIFQ GYGVIFANGE RWRALRRFSL ATMRDFGMGK
	RSVEERIQEE ARCLVEELRK SKGALLDNTL LFHSITSNII CSIVFGKRFD YKDPVFLRLL
	DLFFQSFSLI SSFSSQVFEL FSGFLKYFPG THRQIYRNLQ EINTFIGQSV EKHRATLDPS
	NPRDFIDVYL LRMEKDKSDP SSEFHHQNLI LTVLSLFFAG TETTSTTLRY GFLLMLKYPH
	VTERVQKEIE QVIGSHRPPA LDDRAKMPYT DAVIHEIQRL GDLIPFGVPH TVTKDTQFRG
	YVIPKNTEVF PVLSSALHDP RYFETPNTFN PGHFLDANGA LKRNEGFMPF SLGKRICLGE
	GIARTELFLF FTTILQNFSI ASPVPPEDID LTPRESGVGN VPPSYQIRFL ARHHHH
//
ID	3ME6C	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3ME6
DE	Cytochrome P450 2B4
OS	Oryctolagus cuniculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.100
CC	R-Factor	0.181
FT	#SUB	125	 144 	GLU	C	132	 151 	ARG	A	Protein	S	1
FT	#SUB	132	 151 	ARG	C	125	 144 	GLU	A	Protein	S	1
FT	#SUB	317	 336 	ARG	C	317	 336 	ARG	A	Protein	S	12
FT	#SUB	317	 336 	ARG	C	320	 339 	ALA	A	Protein	S	1
FT	#SUB	317	 336 	ARG	C	322	 341 	ASP	A	Protein	A	2
FT	#SUB	320	 339 	ALA	C	317	 336 	ARG	A	Protein	S	1
FT	#SUB	322	 341 	ASP	C	316	 335 	HIS	A	Protein	S	4
FT	#SUB	298	 317 	TYR	C	397	 416 	ALA	D	Protein	S	2
FT	#SUB	298	 317 	TYR	C	398	 417 	ASN	D	Protein	S	3
FT	#SUB	300	 319 	HIS	C	397	 416 	ALA	D	Protein	S	1
FT	#SUB	300	 319 	HIS	C	398	 417 	ASN	D	Protein	S	7
FT	#SUB	301	 320 	VAL	C	397	 416 	ALA	D	Protein	S	1
FT	#SUB	382	 401 	TYR	C	384	 403 	GLU	D	Protein	B	4
FT	#SUB	383	 402 	PHE	C	384	 403 	GLU	D	Protein	B	3
FT	#SUB	384	 403 	GLU	C	382	 401 	TYR	D	Protein	S	3
FT	#SUB	384	 403 	GLU	C	383	 402 	PHE	D	Protein	S	3
FT	#SUB	384	 403 	GLU	C	384	 403 	GLU	D	Protein	A	15
FT	#SUB	384	 403 	GLU	C	393	 412 	HIS	D	Protein	S	5
FT	#SUB	385	 404 	THR	C	402	 421 	LYS	D	Protein	S	1
FT	#SUB	389	 408 	PHE	C	397	 416 	ALA	D	Protein	B	1
FT	#SUB	390	 409 	ASN	C	395	 414 	LEU	D	Protein	S	1
FT	#SUB	390	 409 	ASN	C	396	 415 	ASP	D	Protein	S	2
FT	#SUB	390	 409 	ASN	C	397	 416 	ALA	D	Protein	S	4
FT	#SUB	390	 409 	ASN	C	402	 421 	LYS	D	Protein	S	1
FT	#SUB	393	 412 	HIS	C	384	 403 	GLU	D	Protein	S	3
FT	#SUB	395	 414 	LEU	C	390	 409 	ASN	D	Protein	B	1
FT	#SUB	396	 415 	ASP	C	390	 409 	ASN	D	Protein	B	4
FT	#SUB	397	 416 	ALA	C	298	 317 	TYR	D	Protein	S	1
FT	#SUB	397	 416 	ALA	C	300	 319 	HIS	D	Protein	B	1
FT	#SUB	397	 416 	ALA	C	301	 320 	VAL	D	Protein	B	1
FT	#SUB	397	 416 	ALA	C	389	 408 	PHE	D	Protein	S	1
FT	#SUB	397	 416 	ALA	C	390	 409 	ASN	D	Protein	B	3
FT	#SUB	398	 417 	ASN	C	298	 317 	TYR	D	Protein	S	3
FT	#SUB	398	 417 	ASN	C	300	 319 	HIS	D	Protein	A	9
FT	#SUB	402	 421 	LYS	C	385	 404 	THR	D	Protein	S	1
FT	#SUB	402	 421 	LYS	C	390	 409 	ASN	D	Protein	S	1
FT	#HET	79	  98 	ARG	C	5	500 	HEM	C	S	7
FT	#HET	85	 104 	VAL	C	6	501 	CGE	C	S	1
FT	#HET	89	 108 	PHE	C	6	501 	CGE	C	S	2
FT	#HET	95	 114 	ILE	C	5	500 	HEM	C	A	3
FT	#HET	102	 121 	TRP	C	5	500 	HEM	C	S	5
FT	#HET	106	 125 	ARG	C	5	500 	HEM	C	S	4
FT	#HET	187	 206 	PHE	C	6	501 	CGE	C	S	4
FT	#HET	190	 209 	ILE	C	6	501 	CGE	C	S	1
FT	#HET	276	 295 	LEU	C	5	500 	HEM	C	S	1
FT	#HET	278	 297 	PHE	C	6	501 	CGE	C	A	26
FT	#HET	279	 298 	ALA	C	5	500 	HEM	C	S	3
FT	#HET	279	 298 	ALA	C	6	501 	CGE	C	A	11
FT	#HET	280	 299 	GLY	C	5	500 	HEM	C	B	6
FT	#HET	283	 302 	THR	C	5	500 	HEM	C	A	7
FT	#HET	283	 302 	THR	C	6	501 	CGE	C	S	4
FT	#HET	284	 303 	THR	C	5	500 	HEM	C	A	3
FT	#HET	338	 357 	GLN	C	5	500 	HEM	C	S	1
FT	#HET	344	 363 	ILE	C	5	500 	HEM	C	S	4
FT	#HET	348	 367 	VAL	C	5	500 	HEM	C	A	4
FT	#HET	348	 367 	VAL	C	6	501 	CGE	C	S	3
FT	#HET	350	 369 	HIS	C	5	500 	HEM	C	S	5
FT	#HET	373	 392 	LEU	C	5	500 	HEM	C	S	1
FT	#HET	409	 428 	PRO	C	5	500 	HEM	C	B	3
FT	#HET	410	 429 	PHE	C	5	500 	HEM	C	A	12
FT	#HET	411	 430 	SER	C	5	500 	HEM	C	S	7
FT	#HET	415	 434 	ARG	C	5	500 	HEM	C	A	15
FT	#HET	417	 436 	CYS	C	5	500 	HEM	C	S	11
FT	#HET	418	 437 	LEU	C	5	500 	HEM	C	S	1
FT	#HET	419	 438 	GLY	C	5	500 	HEM	C	B	4
FT	#HET	423	 442 	ALA	C	5	500 	HEM	C	S	3
FT	#HET	458	 477 	VAL	C	6	501 	CGE	C	A	3
FT	DISORDER	1	8
FT	DISORDER	474	476
CC	SEQUENCE	465 AA (ATOM);
CC	GKLPPGPSPL PVLGNLLQMD RKGLLRSFLR LREKYGDVFT VYLGSRPVVV LCGTDAIREA
CC	LVDQAEAFSG RGKIAVVDPI FQGYGVIFAN GERWRALRRF SLATMRDFGM GKRSVEERIQ
CC	EEARCLVEEL RKSKGALLDN TLLFHSITSN IICSIVFGKR FDYKDPVFLR LLDLFFQSFS
CC	LISSFSSQVF ELFSGFLKYF PGTHRQIYRN LQEINTFIGQ SVEKHRATLD PSNPRDFIDV
CC	YLLRMEKDKS DPSSEFHHQN LILTVLSLFF AGTETTSTTL RYGFLLMLKY PHVTERVQKE
CC	IEQVIGSHRP PALDDRAKMP YTDAVIHEIQ RLGDLIPFGV PHTVTKDTQF RGYVIPKNTE
CC	VFPVLSSALH DPRYFETPNT FNPGHFLDAN GALKRNEGFM PFSLGKRICL GEGIARTELF
CC	LFFTTILQNF SIASPVPPED IDLTPRESGV GNVPPSYQIR FLARH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	ATOM   --------GKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	               ******************************************
CC	SEQRES LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	ATOM   LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	       **************************************************
CC	SEQRES RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	ATOM   RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	       **************************************************
CC	SEQRES LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	ATOM   LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	       **************************************************
CC	SEQRES FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	ATOM   FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	       **************************************************
CC	SEQRES LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	ATOM   VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	       **************************************************
CC	SEQRES TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	ATOM   TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	       **************************************************
CC	SEQRES LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	ATOM   LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	       **************************************************
CC	SEQRES LTPRESGVGNVPPSYQIRFLARHHHH
CC	ATOM   LTPRESGVGNVPPSYQIRFLARH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPSPLPV LGNLLQMDRK GLLRSFLRLR EKYGDVFTVY LGSRPVVVLC
	GTDAIREALV DQAEAFSGRG KIAVVDPIFQ GYGVIFANGE RWRALRRFSL ATMRDFGMGK
	RSVEERIQEE ARCLVEELRK SKGALLDNTL LFHSITSNII CSIVFGKRFD YKDPVFLRLL
	DLFFQSFSLI SSFSSQVFEL FSGFLKYFPG THRQIYRNLQ EINTFIGQSV EKHRATLDPS
	NPRDFIDVYL LRMEKDKSDP SSEFHHQNLI LTVLSLFFAG TETTSTTLRY GFLLMLKYPH
	VTERVQKEIE QVIGSHRPPA LDDRAKMPYT DAVIHEIQRL GDLIPFGVPH TVTKDTQFRG
	YVIPKNTEVF PVLSSALHDP RYFETPNTFN PGHFLDANGA LKRNEGFMPF SLGKRICLGE
	GIARTELFLF FTTILQNFSI ASPVPPEDID LTPRESGVGN VPPSYQIRFL ARHHHH
//
ID	3ME6D	STANDARD;	PRT;	476	AA.
DT	CONVERTED FROM PDB (SEQRES) 3ME6
DE	Cytochrome P450 2B4
OS	Oryctolagus cuniculus
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	3.100
CC	R-Factor	0.181
FT	#SUB	142	 161 	LYS	D	144	 163 	ALA	B	Protein	B	2
FT	#SUB	142	 161 	LYS	D	145	 164 	LEU	B	Protein	B	1
FT	#SUB	142	 161 	LYS	D	468	 487 	ARG	B	Protein	B	3
FT	#SUB	143	 162 	GLY	D	468	 487 	ARG	B	Protein	B	1
FT	#SUB	144	 163 	ALA	D	142	 161 	LYS	B	Protein	B	2
FT	#SUB	144	 163 	ALA	D	144	 163 	ALA	B	Protein	A	2
FT	#SUB	145	 164 	LEU	D	142	 161 	LYS	B	Protein	B	2
FT	#SUB	468	 487 	ARG	D	142	 161 	LYS	B	Protein	S	3
FT	#SUB	468	 487 	ARG	D	143	 162 	GLY	B	Protein	S	1
FT	#SUB	468	 487 	ARG	D	470	 489 	LEU	B	Protein	S	4
FT	#SUB	470	 489 	LEU	D	468	 487 	ARG	B	Protein	S	4
FT	#SUB	298	 317 	TYR	D	397	 416 	ALA	C	Protein	S	1
FT	#SUB	298	 317 	TYR	D	398	 417 	ASN	C	Protein	S	3
FT	#SUB	300	 319 	HIS	D	397	 416 	ALA	C	Protein	S	1
FT	#SUB	300	 319 	HIS	D	398	 417 	ASN	C	Protein	S	9
FT	#SUB	301	 320 	VAL	D	397	 416 	ALA	C	Protein	S	1
FT	#SUB	382	 401 	TYR	D	384	 403 	GLU	C	Protein	B	3
FT	#SUB	383	 402 	PHE	D	384	 403 	GLU	C	Protein	B	3
FT	#SUB	384	 403 	GLU	D	382	 401 	TYR	C	Protein	S	4
FT	#SUB	384	 403 	GLU	D	383	 402 	PHE	C	Protein	S	3
FT	#SUB	384	 403 	GLU	D	384	 403 	GLU	C	Protein	A	15
FT	#SUB	384	 403 	GLU	D	393	 412 	HIS	C	Protein	S	3
FT	#SUB	385	 404 	THR	D	402	 421 	LYS	C	Protein	S	1
FT	#SUB	389	 408 	PHE	D	397	 416 	ALA	C	Protein	B	1
FT	#SUB	390	 409 	ASN	D	395	 414 	LEU	C	Protein	S	1
FT	#SUB	390	 409 	ASN	D	396	 415 	ASP	C	Protein	S	4
FT	#SUB	390	 409 	ASN	D	397	 416 	ALA	C	Protein	S	3
FT	#SUB	390	 409 	ASN	D	402	 421 	LYS	C	Protein	S	1
FT	#SUB	393	 412 	HIS	D	384	 403 	GLU	C	Protein	A	5
FT	#SUB	395	 414 	LEU	D	390	 409 	ASN	C	Protein	B	1
FT	#SUB	396	 415 	ASP	D	390	 409 	ASN	C	Protein	B	2
FT	#SUB	397	 416 	ALA	D	298	 317 	TYR	C	Protein	S	2
FT	#SUB	397	 416 	ALA	D	300	 319 	HIS	C	Protein	B	1
FT	#SUB	397	 416 	ALA	D	301	 320 	VAL	C	Protein	B	1
FT	#SUB	397	 416 	ALA	D	389	 408 	PHE	C	Protein	S	1
FT	#SUB	397	 416 	ALA	D	390	 409 	ASN	C	Protein	A	4
FT	#SUB	398	 417 	ASN	D	298	 317 	TYR	C	Protein	S	3
FT	#SUB	398	 417 	ASN	D	300	 319 	HIS	C	Protein	A	7
FT	#SUB	402	 421 	LYS	D	385	 404 	THR	C	Protein	S	1
FT	#SUB	402	 421 	LYS	D	390	 409 	ASN	C	Protein	S	1
FT	#HET	79	  98 	ARG	D	7	500 	HEM	D	S	8
FT	#HET	85	 104 	VAL	D	8	501 	CGE	D	S	1
FT	#HET	89	 108 	PHE	D	8	501 	CGE	D	S	2
FT	#HET	94	 113 	VAL	D	7	500 	HEM	D	S	1
FT	#HET	95	 114 	ILE	D	7	500 	HEM	D	A	3
FT	#HET	102	 121 	TRP	D	7	500 	HEM	D	S	5
FT	#HET	106	 125 	ARG	D	7	500 	HEM	D	S	4
FT	#HET	187	 206 	PHE	D	8	501 	CGE	D	S	4
FT	#HET	190	 209 	ILE	D	8	501 	CGE	D	S	1
FT	#HET	276	 295 	LEU	D	7	500 	HEM	D	S	2
FT	#HET	278	 297 	PHE	D	8	501 	CGE	D	A	14
FT	#HET	279	 298 	ALA	D	7	500 	HEM	D	A	7
FT	#HET	279	 298 	ALA	D	8	501 	CGE	D	A	11
FT	#HET	280	 299 	GLY	D	7	500 	HEM	D	B	8
FT	#HET	283	 302 	THR	D	7	500 	HEM	D	A	9
FT	#HET	283	 302 	THR	D	8	501 	CGE	D	S	3
FT	#HET	284	 303 	THR	D	7	500 	HEM	D	A	3
FT	#HET	287	 306 	THR	D	7	500 	HEM	D	S	1
FT	#HET	344	 363 	ILE	D	7	500 	HEM	D	S	4
FT	#HET	348	 367 	VAL	D	7	500 	HEM	D	A	2
FT	#HET	348	 367 	VAL	D	8	501 	CGE	D	S	1
FT	#HET	350	 369 	HIS	D	7	500 	HEM	D	S	7
FT	#HET	373	 392 	LEU	D	7	500 	HEM	D	S	1
FT	#HET	409	 428 	PRO	D	7	500 	HEM	D	B	3
FT	#HET	410	 429 	PHE	D	7	500 	HEM	D	A	12
FT	#HET	411	 430 	SER	D	7	500 	HEM	D	S	4
FT	#HET	415	 434 	ARG	D	7	500 	HEM	D	A	14
FT	#HET	417	 436 	CYS	D	7	500 	HEM	D	A	21
FT	#HET	418	 437 	LEU	D	7	500 	HEM	D	S	1
FT	#HET	419	 438 	GLY	D	7	500 	HEM	D	B	5
FT	#HET	423	 442 	ALA	D	7	500 	HEM	D	S	2
FT	#HET	458	 477 	VAL	D	8	501 	CGE	D	A	3
FT	DISORDER	1	8
FT	DISORDER	474	476
CC	SEQUENCE	465 AA (ATOM);
CC	GKLPPGPSPL PVLGNLLQMD RKGLLRSFLR LREKYGDVFT VYLGSRPVVV LCGTDAIREA
CC	LVDQAEAFSG RGKIAVVDPI FQGYGVIFAN GERWRALRRF SLATMRDFGM GKRSVEERIQ
CC	EEARCLVEEL RKSKGALLDN TLLFHSITSN IICSIVFGKR FDYKDPVFLR LLDLFFQSFS
CC	LISSFSSQVF ELFSGFLKYF PGTHRQIYRN LQEINTFIGQ SVEKHRATLD PSNPRDFIDV
CC	YLLRMEKDKS DPSSEFHHQN LILTVLSLFF AGTETTSTTL RYGFLLMLKY PHVTERVQKE
CC	IEQVIGSHRP PALDDRAKMP YTDAVIHEIQ RLGDLIPFGV PHTVTKDTQF RGYVIPKNTE
CC	VFPVLSSALH DPRYFETPNT FNPGHFLDAN GALKRNEGFM PFSLGKRICL GEGIARTELF
CC	LFFTTILQNF SIASPVPPED IDLTPRESGV GNVPPSYQIR FLARH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSKGKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	ATOM   --------GKLPPGPSPLPVLGNLLQMDRKGLLRSFLRLREKYGDVFTVY
CC	               ******************************************
CC	SEQRES LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	ATOM   LGSRPVVVLCGTDAIREALVDQAEAFSGRGKIAVVDPIFQGYGVIFANGE
CC	       **************************************************
CC	SEQRES RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	ATOM   RWRALRRFSLATMRDFGMGKRSVEERIQEEARCLVEELRKSKGALLDNTL
CC	       **************************************************
CC	SEQRES LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	ATOM   LFHSITSNIICSIVFGKRFDYKDPVFLRLLDLFFQSFSLISSFSSQVFEL
CC	       **************************************************
CC	SEQRES FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	ATOM   FSGFLKYFPGTHRQIYRNLQEINTFIGQSVEKHRATLDPSNPRDFIDVYL
CC	       **************************************************
CC	SEQRES LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	ATOM   LRMEKDKSDPSSEFHHQNLILTVLSLFFAGTETTSTTLRYGFLLMLKYPH
CC	       **************************************************
CC	SEQRES VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	ATOM   VTERVQKEIEQVIGSHRPPALDDRAKMPYTDAVIHEIQRLGDLIPFGVPH
CC	       **************************************************
CC	SEQRES TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	ATOM   TVTKDTQFRGYVIPKNTEVFPVLSSALHDPRYFETPNTFNPGHFLDANGA
CC	       **************************************************
CC	SEQRES LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	ATOM   LKRNEGFMPFSLGKRICLGEGIARTELFLFFTTILQNFSIASPVPPEDID
CC	       **************************************************
CC	SEQRES LTPRESGVGNVPPSYQIRFLARHHHH
CC	ATOM   LTPRESGVGNVPPSYQIRFLARH---
CC	       ***********************   
SQ	SEQUENCE	476 AA;      MW;         CN;
	MAKKTSSKGK LPPGPSPLPV LGNLLQMDRK GLLRSFLRLR EKYGDVFTVY LGSRPVVVLC
	GTDAIREALV DQAEAFSGRG KIAVVDPIFQ GYGVIFANGE RWRALRRFSL ATMRDFGMGK
	RSVEERIQEE ARCLVEELRK SKGALLDNTL LFHSITSNII CSIVFGKRFD YKDPVFLRLL
	DLFFQSFSLI SSFSSQVFEL FSGFLKYFPG THRQIYRNLQ EINTFIGQSV EKHRATLDPS
	NPRDFIDVYL LRMEKDKSDP SSEFHHQNLI LTVLSLFFAG TETTSTTLRY GFLLMLKYPH
	VTERVQKEIE QVIGSHRPPA LDDRAKMPYT DAVIHEIQRL GDLIPFGVPH TVTKDTQFRG
	YVIPKNTEVF PVLSSALHDP RYFETPNTFN PGHFLDANGA LKRNEGFMPF SLGKRICLGE
	GIARTELFLF FTTILQNFSI ASPVPPEDID LTPRESGVGN VPPSYQIRFL ARHHHH
//