ID	3MDVA	STANDARD;	PRT;	456	AA.
DT	CONVERTED FROM PDB (SEQRES) 3MDV
DE	Cholesterol 24-hydroxylase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.210
FT	#SUB	41	  89 	SER	A	376	 424 	ARG	B	Protein	S	1
FT	#SUB	42	  90 	PRO	A	376	 424 	ARG	B	Protein	S	5
FT	#SUB	43	  91 	GLU	A	43	  91 	GLU	B	Protein	S	1
FT	#SUB	43	  91 	GLU	A	46	  94 	LYS	B	Protein	S	4
FT	#SUB	43	  91 	GLU	A	376	 424 	ARG	B	Protein	S	6
FT	#SUB	46	  94 	LYS	A	43	  91 	GLU	B	Protein	S	6
FT	#SUB	46	  94 	LYS	A	333	 381 	ASP	B	Protein	S	1
FT	#SUB	333	 381 	ASP	A	46	  94 	LYS	B	Protein	S	1
FT	#SUB	355	 403 	THR	A	373	 421 	PRO	B	Protein	B	1
FT	#SUB	358	 406 	GLU	A	371	 419 	GLY	B	Protein	S	2
FT	#SUB	358	 406 	GLU	A	372	 420 	ALA	B	Protein	S	7
FT	#SUB	358	 406 	GLU	A	373	 421 	PRO	B	Protein	A	2
FT	#SUB	371	 419 	GLY	A	358	 406 	GLU	B	Protein	B	2
FT	#SUB	372	 420 	ALA	A	358	 406 	GLU	B	Protein	B	3
FT	#SUB	373	 421 	PRO	A	354	 402 	ASP	B	Protein	S	1
FT	#SUB	373	 421 	PRO	A	355	 403 	THR	B	Protein	S	1
FT	#SUB	373	 421 	PRO	A	358	 406 	GLU	B	Protein	S	2
FT	#SUB	376	 424 	ARG	A	41	  89 	SER	B	Protein	S	1
FT	#SUB	376	 424 	ARG	A	42	  90 	PRO	B	Protein	S	5
FT	#SUB	376	 424 	ARG	A	43	  91 	GLU	B	Protein	S	6
FT	#HET	56	 104 	LYS	A	1	505 	HEM	A	S	6
FT	#HET	61	 109 	TYR	A	1	505 	HEM	A	S	5
FT	#HET	61	 109 	TYR	A	2	506 	CL6	A	S	1
FT	#HET	64	 112 	LEU	A	2	506 	CL6	A	S	6
FT	#HET	73	 121 	PHE	A	2	506 	CL6	A	S	18
FT	#HET	77	 125 	LEU	A	1	505 	HEM	A	A	4
FT	#HET	78	 126 	VAL	A	1	505 	HEM	A	A	4
FT	#HET	78	 126 	VAL	A	2	506 	CL6	A	S	7
FT	#HET	86	 134 	TRP	A	1	505 	HEM	A	S	6
FT	#HET	90	 138 	ARG	A	1	505 	HEM	A	S	5
FT	#HET	97	 145 	PHE	A	1	505 	HEM	A	S	1
FT	#HET	171	 219 	LEU	A	2	506 	CL6	A	S	2
FT	#HET	251	 299 	PHE	A	1	505 	HEM	A	S	2
FT	#HET	253	 301 	ILE	A	2	506 	CL6	A	S	3
FT	#HET	254	 302 	ALA	A	1	505 	HEM	A	A	9
FT	#HET	254	 302 	ALA	A	2	506 	CL6	A	S	2
FT	#HET	255	 303 	GLY	A	1	505 	HEM	A	B	4
FT	#HET	257	 305 	GLU	A	2	506 	CL6	A	S	2
FT	#HET	258	 306 	THR	A	1	505 	HEM	A	A	15
FT	#HET	259	 307 	SER	A	1	505 	HEM	A	A	6
FT	#HET	262	 310 	HIS	A	1	505 	HEM	A	S	3
FT	#HET	319	 367 	ALA	A	1	505 	HEM	A	S	1
FT	#HET	322	 370 	THR	A	1	505 	HEM	A	S	3
FT	#HET	381	 429 	PRO	A	1	505 	HEM	A	B	3
FT	#HET	382	 430 	PHE	A	1	505 	HEM	A	A	10
FT	#HET	383	 431 	SER	A	1	505 	HEM	A	A	3
FT	#HET	387	 435 	ARG	A	1	505 	HEM	A	A	7
FT	#HET	388	 436 	SER	A	1	505 	HEM	A	B	2
FT	#HET	389	 437 	CYS	A	1	505 	HEM	A	A	21
FT	#HET	390	 438 	ILE	A	1	505 	HEM	A	A	4
FT	#HET	391	 439 	GLY	A	1	505 	HEM	A	B	2
FT	#HET	394	 442 	PHE	A	1	505 	HEM	A	S	6
FT	#HET	395	 443 	ALA	A	1	505 	HEM	A	S	3
FT	#HET	398	 446 	GLU	A	1	505 	HEM	A	S	1
FT	#HET	426	 474 	ALA	A	2	506 	CL6	A	S	1
FT	#HET	427	 475 	THR	A	2	506 	CL6	A	S	3
FT	DISORDER	1	10
FT	DISORDER	181	187
FT	DISORDER	442	456
CC	SEQUENCE	424 AA (ATOM);
CC	VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM YRALQTVFGE
CC	RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL EAKADGQTPV
CC	SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT KRKQLREVRE
CC	SIRFLRQVGR DWVQRRREAL KRGEEVPADI LTQILKAEEG AQDDEGLLDN FVTFFIAGHE
CC	TSANHLAFTV MELSRQPEIV ARLQAEVDEV IGSKRYLDFE DLGRLQYLSQ VLKESLRLYP
CC	PAWGTFRLLE EETLIDGVRV PGNTPLLFST YVMGRMDTYF EDPLTFNPDR FGPGAPKPRF
CC	TYFPFSLGHR SCIGQQFAQM EVKVVMAKLL QRLEFRLVPG QRFGLQEQAT LKPLDPVLCT
CC	LRPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	ATOM   ----------VLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	                 ****************************************
CC	SEQRES STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	ATOM   STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	       **************************************************
CC	SEQRES SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	ATOM   SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	       **************************************************
CC	SEQRES METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	ATOM   METSMLLGAQKPLSQAVKLMLEGITASRNT-------KRKQLREVRESIR
CC	       ******************************       *************
CC	SEQRES FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	ATOM   FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	       **************************************************
CC	SEQRES FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	ATOM   FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	       **************************************************
CC	SEQRES RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	ATOM   RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	       **************************************************
CC	SEQRES GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	ATOM   GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	       **************************************************
CC	SEQRES VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPP
CC	ATOM   VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPR---------
CC	       *****************************************         
CC	SEQRES PCHHHH
CC	ATOM   ------
CC	             
SQ	SEQUENCE	456 AA;      MW;         CN;
	MAKKDEVGGR VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM
	YRALQTVFGE RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL
	EAKADGQTPV SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT
	LAKFLPGKRK QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD
	DEGLLDNFVT FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG
	RLQYLSQVLK ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP
	LTFNPDRFGP GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF
	GLQEQATLKP LDPVLCTLRP RGWQPAPPPP PCHHHH
//
ID	3MDVB	STANDARD;	PRT;	456	AA.
DT	CONVERTED FROM PDB (SEQRES) 3MDV
DE	Cholesterol 24-hydroxylase
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.400
CC	R-Factor	0.210
FT	#SUB	41	  89 	SER	B	376	 424 	ARG	A	Protein	S	1
FT	#SUB	42	  90 	PRO	B	376	 424 	ARG	A	Protein	S	5
FT	#SUB	43	  91 	GLU	B	43	  91 	GLU	A	Protein	S	1
FT	#SUB	43	  91 	GLU	B	46	  94 	LYS	A	Protein	S	6
FT	#SUB	43	  91 	GLU	B	376	 424 	ARG	A	Protein	S	6
FT	#SUB	46	  94 	LYS	B	43	  91 	GLU	A	Protein	S	4
FT	#SUB	46	  94 	LYS	B	333	 381 	ASP	A	Protein	S	1
FT	#SUB	333	 381 	ASP	B	46	  94 	LYS	A	Protein	S	1
FT	#SUB	354	 402 	ASP	B	373	 421 	PRO	A	Protein	B	1
FT	#SUB	355	 403 	THR	B	373	 421 	PRO	A	Protein	B	1
FT	#SUB	358	 406 	GLU	B	371	 419 	GLY	A	Protein	S	2
FT	#SUB	358	 406 	GLU	B	372	 420 	ALA	A	Protein	S	3
FT	#SUB	358	 406 	GLU	B	373	 421 	PRO	A	Protein	A	2
FT	#SUB	371	 419 	GLY	B	358	 406 	GLU	A	Protein	B	2
FT	#SUB	372	 420 	ALA	B	358	 406 	GLU	A	Protein	A	7
FT	#SUB	373	 421 	PRO	B	355	 403 	THR	A	Protein	S	1
FT	#SUB	373	 421 	PRO	B	358	 406 	GLU	A	Protein	S	2
FT	#SUB	376	 424 	ARG	B	41	  89 	SER	A	Protein	S	1
FT	#SUB	376	 424 	ARG	B	42	  90 	PRO	A	Protein	S	5
FT	#SUB	376	 424 	ARG	B	43	  91 	GLU	A	Protein	S	6
FT	#HET	56	 104 	LYS	B	3	505 	HEM	B	S	7
FT	#HET	61	 109 	TYR	B	3	505 	HEM	B	S	5
FT	#HET	61	 109 	TYR	B	4	506 	CL6	B	S	1
FT	#HET	64	 112 	LEU	B	4	506 	CL6	B	S	4
FT	#HET	73	 121 	PHE	B	4	506 	CL6	B	S	13
FT	#HET	77	 125 	LEU	B	3	505 	HEM	B	A	8
FT	#HET	78	 126 	VAL	B	3	505 	HEM	B	A	4
FT	#HET	78	 126 	VAL	B	4	506 	CL6	B	S	6
FT	#HET	86	 134 	TRP	B	3	505 	HEM	B	S	7
FT	#HET	90	 138 	ARG	B	3	505 	HEM	B	S	6
FT	#HET	171	 219 	LEU	B	4	506 	CL6	B	S	2
FT	#HET	250	 298 	THR	B	4	506 	CL6	B	A	2
FT	#HET	251	 299 	PHE	B	3	505 	HEM	B	S	3
FT	#HET	253	 301 	ILE	B	4	506 	CL6	B	S	3
FT	#HET	254	 302 	ALA	B	3	505 	HEM	B	A	11
FT	#HET	254	 302 	ALA	B	4	506 	CL6	B	S	3
FT	#HET	255	 303 	GLY	B	3	505 	HEM	B	B	8
FT	#HET	257	 305 	GLU	B	4	506 	CL6	B	S	4
FT	#HET	258	 306 	THR	B	3	505 	HEM	B	A	14
FT	#HET	258	 306 	THR	B	4	506 	CL6	B	S	3
FT	#HET	259	 307 	SER	B	3	505 	HEM	B	A	6
FT	#HET	262	 310 	HIS	B	3	505 	HEM	B	S	1
FT	#HET	319	 367 	ALA	B	3	505 	HEM	B	S	1
FT	#HET	319	 367 	ALA	B	4	506 	CL6	B	S	2
FT	#HET	322	 370 	THR	B	3	505 	HEM	B	S	4
FT	#HET	381	 429 	PRO	B	3	505 	HEM	B	B	3
FT	#HET	382	 430 	PHE	B	3	505 	HEM	B	S	9
FT	#HET	387	 435 	ARG	B	3	505 	HEM	B	S	3
FT	#HET	388	 436 	SER	B	3	505 	HEM	B	B	1
FT	#HET	389	 437 	CYS	B	3	505 	HEM	B	A	22
FT	#HET	390	 438 	ILE	B	3	505 	HEM	B	A	4
FT	#HET	391	 439 	GLY	B	3	505 	HEM	B	B	1
FT	#HET	394	 442 	PHE	B	3	505 	HEM	B	S	1
FT	#HET	395	 443 	ALA	B	3	505 	HEM	B	S	3
FT	#HET	398	 446 	GLU	B	3	505 	HEM	B	S	1
FT	#HET	426	 474 	ALA	B	4	506 	CL6	B	A	3
FT	#HET	427	 475 	THR	B	4	506 	CL6	B	S	3
FT	DISORDER	1	10
FT	DISORDER	181	187
FT	DISORDER	442	456
CC	SEQUENCE	424 AA (ATOM);
CC	VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM YRALQTVFGE
CC	RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL EAKADGQTPV
CC	SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT KRKQLREVRE
CC	SIRFLRQVGR DWVQRRREAL KRGEEVPADI LTQILKAEEG AQDDEGLLDN FVTFFIAGHE
CC	TSANHLAFTV MELSRQPEIV ARLQAEVDEV IGSKRYLDFE DLGRLQYLSQ VLKESLRLYP
CC	PAWGTFRLLE EETLIDGVRV PGNTPLLFST YVMGRMDTYF EDPLTFNPDR FGPGAPKPRF
CC	TYFPFSLGHR SCIGQQFAQM EVKVVMAKLL QRLEFRLVPG QRFGLQEQAT LKPLDPVLCT
CC	LRPR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	ATOM   ----------VLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	                 ****************************************
CC	SEQRES STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	ATOM   STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	       **************************************************
CC	SEQRES SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	ATOM   SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	       **************************************************
CC	SEQRES METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	ATOM   METSMLLGAQKPLSQAVKLMLEGITASRNT-------KRKQLREVRESIR
CC	       ******************************       *************
CC	SEQRES FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	ATOM   FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	       **************************************************
CC	SEQRES FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	ATOM   FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	       **************************************************
CC	SEQRES RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	ATOM   RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	       **************************************************
CC	SEQRES GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	ATOM   GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	       **************************************************
CC	SEQRES VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPP
CC	ATOM   VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPR---------
CC	       *****************************************         
CC	SEQRES PCHHHH
CC	ATOM   ------
CC	             
SQ	SEQUENCE	456 AA;      MW;         CN;
	MAKKDEVGGR VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM
	YRALQTVFGE RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL
	EAKADGQTPV SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT
	LAKFLPGKRK QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD
	DEGLLDNFVT FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG
	RLQYLSQVLK ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP
	LTFNPDRFGP GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF
	GLQEQATLKP LDPVLCTLRP RGWQPAPPPP PCHHHH
//