ID	3KKTA	STANDARD;	PRT;	398	AA.
DT	CONVERTED FROM PDB (SEQRES) 3KKT
DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4B
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.480
CC	R-Factor	0.238
FT	#SUB	158	 288 	ASN	A	202	 332 	GLN	B	Protein	S	1
FT	#SUB	164	 294 	ALA	A	205	 335 	ARG	B	Protein	B	2
FT	#SUB	165	 295 	LEU	A	205	 335 	ARG	B	Protein	A	2
FT	#SUB	166	 296 	MET	A	166	 296 	MET	B	Protein	S	3
FT	#SUB	166	 296 	MET	A	167	 297 	TYR	B	Protein	B	3
FT	#SUB	166	 296 	MET	A	179	 309 	ALA	B	Protein	S	1
FT	#SUB	167	 297 	TYR	A	166	 296 	MET	B	Protein	S	5
FT	#SUB	167	 297 	TYR	A	167	 297 	TYR	B	Protein	S	3
FT	#SUB	168	 298 	ASN	A	175	 305 	ASN	B	Protein	S	7
FT	#SUB	168	 298 	ASN	A	178	 308 	LEU	B	Protein	S	5
FT	#SUB	168	 298 	ASN	A	179	 309 	ALA	B	Protein	S	1
FT	#SUB	168	 298 	ASN	A	205	 335 	ARG	B	Protein	B	2
FT	#SUB	168	 298 	ASN	A	209	 339 	ILE	B	Protein	A	4
FT	#SUB	169	 299 	ASP	A	205	 335 	ARG	B	Protein	A	12
FT	#SUB	175	 305 	ASN	A	168	 298 	ASN	B	Protein	A	8
FT	#SUB	178	 308 	LEU	A	168	 298 	ASN	B	Protein	A	3
FT	#SUB	179	 309 	ALA	A	168	 298 	ASN	B	Protein	B	2
FT	#SUB	202	 332 	GLN	A	158	 288 	ASN	B	Protein	S	1
FT	#SUB	205	 335 	ARG	A	164	 294 	ALA	B	Protein	S	2
FT	#SUB	205	 335 	ARG	A	165	 295 	LEU	B	Protein	S	3
FT	#SUB	205	 335 	ARG	A	168	 298 	ASN	B	Protein	S	1
FT	#SUB	205	 335 	ARG	A	169	 299 	ASP	B	Protein	S	8
FT	#SUB	209	 339 	ILE	A	168	 298 	ASN	B	Protein	S	5
FT	#SUB	209	 339 	ILE	A	169	 299 	ASP	B	Protein	S	1
FT	#SUB	213	 343 	LEU	A	170	 300 	GLU	B	Protein	S	1
FT	#SUB	298	 428 	ILE	A	202	 332 	GLN	B	Protein	S	1
FT	#HET	103	 233 	TYR	A	2	2 	0CP	A	S	3
FT	#HET	108	 238 	HIS	A	1	1 	ZN	A	S	3
FT	#HET	144	 274 	HIS	A	1	1 	ZN	A	S	3
FT	#HET	145	 275 	ASP	A	1	1 	ZN	A	S	3
FT	#HET	145	 275 	ASP	A	3	529 	MG	A	S	3
FT	#HET	217	 347 	MET	A	2	2 	0CP	A	S	1
FT	#HET	262	 392 	ASP	A	1	1 	ZN	A	S	3
FT	#HET	263	 393 	LEU	A	2	2 	0CP	A	S	1
FT	#HET	265	 395 	ASN	A	2	2 	0CP	A	S	1
FT	#HET	273	 403 	TYR	A	2	2 	0CP	A	S	1
FT	#HET	277	 407 	THR	A	2	2 	0CP	A	A	3
FT	#HET	280	 410 	ILE	A	2	2 	0CP	A	S	9
FT	#HET	281	 411 	MET	A	2	2 	0CP	A	S	2
FT	#HET	284	 414 	PHE	A	2	2 	0CP	A	S	1
FT	#HET	312	 442 	SER	A	2	2 	0CP	A	A	3
FT	#HET	313	 443 	GLN	A	2	2 	0CP	A	S	8
FT	#HET	316	 446 	PHE	A	2	2 	0CP	A	S	12
FT	#HET	372	 502 	LEU	A	2	2 	0CP	A	A	5
FT	#HET	373	 503 	MET	A	2	2 	0CP	A	S	1
FT	DISORDER	1	32
FT	DISORDER	380	398
CC	SEQUENCE	347 AA (ATOM);
CC	EDHLAKELED LNKWGLNIFN VAGYSHNRPL TCIMYAIFQE RDLLKTFRIS SDTFITYMMT
CC	LEDHYHSDVA YHNSLHAADV AQSTHVLLST PALDAVFTDL EILAAIFAAA IHDVDHPGVS
CC	NQFLINTNSE LALMYNDESV LENHHLAVGF KLLQEEHCDI FMNLTKKQRQ TLRKMVIDMV
CC	LATDMSKHMS LLADLKTMVE TKKVTSSGVL LLDNYTDRIQ VLRNMVHCAD LSNPTKSLEL
CC	YRQWTDRIME EFFQQGDKER ERGMEISPMC DKHTASVEKS QVGFIDYIVH PLWETWADLV
CC	QPDAQDILDT LEDNRNWYQS MIPQSPSPPL DEQNRDCQGL MEKFQFE
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHMSISRFGVNTENEDHLAKELEDLNKWGLNI
CC	ATOM   --------------------------------EDHLAKELEDLNKWGLNI
CC	                                       ******************
CC	SEQRES FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	ATOM   FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	       **************************************************
CC	SEQRES VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	ATOM   VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	       **************************************************
CC	SEQRES VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQ
CC	ATOM   VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQ
CC	       **************************************************
CC	SEQRES RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	ATOM   RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	       **************************************************
CC	SEQRES IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	ATOM   IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	       **************************************************
CC	SEQRES MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	ATOM   MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	       **************************************************
CC	SEQRES QSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHS
CC	ATOM   QSMIPQSPSPPLDEQNRDCQGLMEKFQFE-------------------
CC	       *****************************                   
SQ	SEQUENCE	398 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH MSISRFGVNT ENEDHLAKEL EDLNKWGLNI FNVAGYSHNR
	PLTCIMYAIF QERDLLKTFR ISSDTFITYM MTLEDHYHSD VAYHNSLHAA DVAQSTHVLL
	STPALDAVFT DLEILAAIFA AAIHDVDHPG VSNQFLINTN SELALMYNDE SVLENHHLAV
	GFKLLQEEHC DIFMNLTKKQ RQTLRKMVID MVLATDMSKH MSLLADLKTM VETKKVTSSG
	VLLLDNYTDR IQVLRNMVHC ADLSNPTKSL ELYRQWTDRI MEEFFQQGDK ERERGMEISP
	MCDKHTASVE KSQVGFIDYI VHPLWETWAD LVQPDAQDIL DTLEDNRNWY QSMIPQSPSP
	PLDEQNRDCQ GLMEKFQFEL TLDEEDSEGP EKEGEGHS
//
ID	3KKTB	STANDARD;	PRT;	398	AA.
DT	CONVERTED FROM PDB (SEQRES) 3KKT
DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4B
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.480
CC	R-Factor	0.238
FT	#SUB	158	 288 	ASN	B	202	 332 	GLN	A	Protein	S	1
FT	#SUB	164	 294 	ALA	B	205	 335 	ARG	A	Protein	B	2
FT	#SUB	165	 295 	LEU	B	205	 335 	ARG	A	Protein	A	3
FT	#SUB	166	 296 	MET	B	166	 296 	MET	A	Protein	S	3
FT	#SUB	166	 296 	MET	B	167	 297 	TYR	A	Protein	A	5
FT	#SUB	167	 297 	TYR	B	166	 296 	MET	A	Protein	S	3
FT	#SUB	167	 297 	TYR	B	167	 297 	TYR	A	Protein	S	3
FT	#SUB	168	 298 	ASN	B	175	 305 	ASN	A	Protein	S	8
FT	#SUB	168	 298 	ASN	B	178	 308 	LEU	A	Protein	S	3
FT	#SUB	168	 298 	ASN	B	179	 309 	ALA	A	Protein	S	2
FT	#SUB	168	 298 	ASN	B	205	 335 	ARG	A	Protein	B	1
FT	#SUB	168	 298 	ASN	B	209	 339 	ILE	A	Protein	A	5
FT	#SUB	169	 299 	ASP	B	205	 335 	ARG	A	Protein	S	8
FT	#SUB	169	 299 	ASP	B	209	 339 	ILE	A	Protein	S	1
FT	#SUB	170	 300 	GLU	B	213	 343 	LEU	A	Protein	S	1
FT	#SUB	175	 305 	ASN	B	168	 298 	ASN	A	Protein	A	7
FT	#SUB	178	 308 	LEU	B	168	 298 	ASN	A	Protein	A	5
FT	#SUB	179	 309 	ALA	B	166	 296 	MET	A	Protein	S	1
FT	#SUB	179	 309 	ALA	B	168	 298 	ASN	A	Protein	B	1
FT	#SUB	202	 332 	GLN	B	158	 288 	ASN	A	Protein	S	1
FT	#SUB	202	 332 	GLN	B	298	 428 	ILE	A	Protein	S	1
FT	#SUB	205	 335 	ARG	B	164	 294 	ALA	A	Protein	S	2
FT	#SUB	205	 335 	ARG	B	165	 295 	LEU	A	Protein	S	2
FT	#SUB	205	 335 	ARG	B	168	 298 	ASN	A	Protein	S	2
FT	#SUB	205	 335 	ARG	B	169	 299 	ASP	A	Protein	S	12
FT	#SUB	209	 339 	ILE	B	168	 298 	ASN	A	Protein	S	4
FT	#HET	98	 228 	HIS	B	6	529 	B3P	B	S	1
FT	#HET	103	 233 	TYR	B	5	1 	0CP	B	S	6
FT	#HET	108	 238 	HIS	B	4	2 	ZN	B	S	3
FT	#HET	144	 274 	HIS	B	4	2 	ZN	B	S	3
FT	#HET	144	 274 	HIS	B	7	530 	MG	B	B	1
FT	#HET	145	 275 	ASP	B	4	2 	ZN	B	S	3
FT	#HET	145	 275 	ASP	B	7	530 	MG	B	S	3
FT	#HET	147	 277 	ASP	B	6	529 	B3P	B	A	11
FT	#HET	149	 279 	PRO	B	6	529 	B3P	B	S	5
FT	#HET	174	 304 	GLU	B	7	530 	MG	B	S	1
FT	#HET	177	 307 	HIS	B	7	530 	MG	B	S	1
FT	#HET	217	 347 	MET	B	5	1 	0CP	B	S	1
FT	#HET	262	 392 	ASP	B	4	2 	ZN	B	S	3
FT	#HET	263	 393 	LEU	B	5	1 	0CP	B	S	1
FT	#HET	265	 395 	ASN	B	5	1 	0CP	B	S	3
FT	#HET	273	 403 	TYR	B	5	1 	0CP	B	S	1
FT	#HET	277	 407 	THR	B	5	1 	0CP	B	A	3
FT	#HET	280	 410 	ILE	B	5	1 	0CP	B	S	7
FT	#HET	284	 414 	PHE	B	5	1 	0CP	B	S	2
FT	#HET	312	 442 	SER	B	5	1 	0CP	B	A	3
FT	#HET	313	 443 	GLN	B	5	1 	0CP	B	S	4
FT	#HET	316	 446 	PHE	B	5	1 	0CP	B	S	10
FT	#HET	372	 502 	LEU	B	5	1 	0CP	B	B	2
FT	#HET	373	 503 	MET	B	5	1 	0CP	B	A	3
FT	#HET	376	 506 	PHE	B	5	1 	0CP	B	S	6
FT	DISORDER	1	23
FT	DISORDER	305	308
FT	DISORDER	354	368
FT	DISORDER	381	398
CC	SEQUENCE	338 AA (ATOM);
CC	SRFGVNTENE DHLAKELEDL NKWGLNIFNV AGYSHNRPLT CIMYAIFQER DLLKTFRISS
CC	DTFITYMMTL EDHYHSDVAY HNSLHAADVA QSTHVLLSTP ALDAVFTDLE ILAAIFAAAI
CC	HDVDHPGVSN QFLINTNSEL ALMYNDESVL ENHHLAVGFK LLQEEHCDIF MNLTKKQRQT
CC	LRKMVIDMVL ATDMSKHMSL LADLKTMVET KKVTSSGVLL LDNYTDRIQV LRNMVHCADL
CC	SNPTKSLELY RQWTDRIMEE FFQQGDKERE RGMEISPMCD KVEKSQVGFI DYIVHPLWET
CC	WADLVQPDAQ DILDTLEDNR NWYQSMCQGL MEKFQFEL
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHMSISRFGVNTENEDHLAKELEDLNKWGLNI
CC	ATOM   -----------------------SRFGVNTENEDHLAKELEDLNKWGLNI
CC	                              ***************************
CC	SEQRES FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	ATOM   FNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	       **************************************************
CC	SEQRES VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	ATOM   VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	       **************************************************
CC	SEQRES VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQ
CC	ATOM   VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQ
CC	       **************************************************
CC	SEQRES RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	ATOM   RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	       **************************************************
CC	SEQRES IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	ATOM   IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	       **************************************************
CC	SEQRES MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	ATOM   MCDK----VEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	       ****    ******************************************
CC	SEQRES QSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHS
CC	ATOM   QSM---------------CQGLMEKFQFEL------------------
CC	       ***               ************                  
SQ	SEQUENCE	398 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH MSISRFGVNT ENEDHLAKEL EDLNKWGLNI FNVAGYSHNR
	PLTCIMYAIF QERDLLKTFR ISSDTFITYM MTLEDHYHSD VAYHNSLHAA DVAQSTHVLL
	STPALDAVFT DLEILAAIFA AAIHDVDHPG VSNQFLINTN SELALMYNDE SVLENHHLAV
	GFKLLQEEHC DIFMNLTKKQ RQTLRKMVID MVLATDMSKH MSLLADLKTM VETKKVTSSG
	VLLLDNYTDR IQVLRNMVHC ADLSNPTKSL ELYRQWTDRI MEEFFQQGDK ERERGMEISP
	MCDKHTASVE KSQVGFIDYI VHPLWETWAD LVQPDAQDIL DTLEDNRNWY QSMIPQSPSP
	PLDEQNRDCQ GLMEKFQFEL TLDEEDSEGP EKEGEGHS
//