ID	3JY9A	STANDARD;	PRT;	311	AA.
DT	CONVERTED FROM PDB (SEQRES) 3JY9
DE	Tyrosine-protein kinase JAK2
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.100
CC	R-Factor	0.201
FT	#HET	27	 846 	GLU	A	2	1131 	NA	A	S	1
FT	#HET	36	 855 	LEU	A	1	1 	JZH	A	A	4
FT	#HET	37	 856 	GLY	A	1	1 	JZH	A	B	2
FT	#HET	44	 863 	VAL	A	1	1 	JZH	A	S	3
FT	#HET	45	 864 	GLU	A	2	1131 	NA	A	S	1
FT	#HET	61	 880 	ALA	A	1	1 	JZH	A	S	2
FT	#HET	79	 898 	GLU	A	1	1 	JZH	A	S	5
FT	#HET	92	 911 	VAL	A	1	1 	JZH	A	S	4
FT	#HET	107	 926 	LYS	A	2	1131 	NA	A	S	1
FT	#HET	110	 929 	MET	A	1	1 	JZH	A	S	7
FT	#HET	111	 930 	GLU	A	1	1 	JZH	A	B	3
FT	#HET	112	 931 	TYR	A	1	1 	JZH	A	A	4
FT	#HET	113	 932 	LEU	A	1	1 	JZH	A	B	4
FT	#HET	164	 983 	LEU	A	1	1 	JZH	A	S	9
FT	#HET	174	 993 	GLY	A	1	1 	JZH	A	B	2
FT	#HET	175	 994 	ASP	A	1	1 	JZH	A	A	12
FT	#HET	176	 995 	PHE	A	1	1 	JZH	A	A	4
FT	DISORDER	1	22
FT	DISORDER	40	41
FT	DISORDER	101	103
CC	SEQUENCE	284 AA (ATOM);
CC	TQFEERHLKF LQQLGKGGSV EMCRYDPLQD NTGEVVAVKK LQHSTEEHLR DFEREIEILK
CC	SLQHDNIVKY KGVCYSRNLK LIMEYLPYGS LRDYLQKHKE RIDHIKLLQY TSQICKGMEY
CC	LGTKRYIHRD LATRNILVEN ENRVKIGDFG LTKVLPQDKE YYKVKEPGES PIFWYAPESL
CC	TESKFSVASD VWSFGVVLYE LFTYIEKSKS PPAEFMRMIG NDKQGQMIVF HLIELLKNNG
CC	RLPRPDGCPD EIYMIMTECW NNNVNQRPSF RDLALRVDQI RDNM
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHNMTQFEERHLKFLQQLGKGNFGSVEMCRYD
CC	ATOM   ----------------------TQFEERHLKFLQQLGKG--GSVEMCRYD
CC	                             *****************  *********
CC	SEQRES PLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYS
CC	ATOM   PLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYS
CC	       **************************************************
CC	SEQRES AGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGT
CC	ATOM   ---RNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGT
CC	          ***********************************************
CC	SEQRES KRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF
CC	ATOM   KRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIF
CC	       **************************************************
CC	SEQRES WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDK
CC	ATOM   WYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDK
CC	       **************************************************
CC	SEQRES QGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDL
CC	ATOM   QGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDL
CC	       **************************************************
CC	SEQRES ALRVDQIRDNM
CC	ATOM   ALRVDQIRDNM
CC	       ***********
SQ	SEQUENCE	311 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH NMTQFEERHL KFLQQLGKGN FGSVEMCRYD PLQDNTGEVV
	AVKKLQHSTE EHLRDFEREI EILKSLQHDN IVKYKGVCYS AGRRNLKLIM EYLPYGSLRD
	YLQKHKERID HIKLLQYTSQ ICKGMEYLGT KRYIHRDLAT RNILVENENR VKIGDFGLTK
	VLPQDKEYYK VKEPGESPIF WYAPESLTES KFSVASDVWS FGVVLYELFT YIEKSKSPPA
	EFMRMIGNDK QGQMIVFHLI ELLKNNGRLP RPDGCPDEIY MIMTECWNNN VNQRPSFRDL
	ALRVDQIRDN M
//