ID	2ZJIA	STANDARD;	PRT;	405	AA.
DT	CONVERTED FROM PDB (SEQRES) 2ZJI
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.236
FT	#HET	50	  30 	LEU	A	1	449 	F1I	A	S	2
FT	#HET	52	  32 	ASP	A	1	449 	F1I	A	S	4
FT	#HET	54	  34 	GLY	A	1	449 	F1I	A	B	3
FT	#HET	55	  35 	SER	A	1	449 	F1I	A	S	1
FT	#HET	91	  71 	TYR	A	1	449 	F1I	A	S	8
FT	#HET	96	  76 	TRP	A	1	449 	F1I	A	S	2
FT	#HET	128	 108 	PHE	A	1	449 	F1I	A	S	4
FT	#HET	138	 118 	ILE	A	1	449 	F1I	A	S	1
FT	#HET	246	 226 	ILE	A	1	449 	F1I	A	S	1
FT	#HET	248	 228 	ASP	A	1	449 	F1I	A	S	4
FT	#HET	250	 230 	GLY	A	1	449 	F1I	A	B	1
FT	#HET	251	 231 	THR	A	1	449 	F1I	A	S	1
FT	#HET	255	 235 	ARG	A	1	449 	F1I	A	S	2
FT	#HET	349	 329 	CYS	A	1	449 	F1I	A	A	8
FT	#HET	352	 332 	VAL	A	1	449 	F1I	A	S	2
FT	DISORDER	1	15
FT	DISORDER	177	188
FT	DISORDER	330	337
CC	Miss-SC	1
CC	SEQUENCE	370 AA (ATOM);
CC	RGSFVEMVDN LRGKSGQGYY VEMTVGSPPQ TLNILVDTGS SNFAVGAAPH PFLHRYYQRQ
CC	LSSTYRDLRK GVYVPYTQGK WEGELGTDLV SIPHGPNVTV RANIAAITES DKFFINGSNW
CC	EGILGLAYAE IARPDDSLEP FFDSLVKQTH VPNLFSLQLC GSVGGSMIIG GIDHSLYTGS
CC	LWYTPIRREW YYEVIIVRVE INGQDLKMDC KEYNYDKSIV DSGTTNLRLP KKVFEAAVKS
CC	IKAASSTEKF PDGFWLGEQL VCWQAGTTPW NIFPVISLYL MGEVTNQSFR ITILPQQYLR
CC	PVDCYKFAIS QSSCGTVMGA VIMEGFYVVF DRARKRIGFA VSACHVHDEF RTAAVEGPFV
CC	TLDMEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MLPRETDEEPEEPGRRGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNIL
CC	ATOM   ---------------RGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNIL
CC	                      ***********************************
CC	SEQRES VDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGEL
CC	ATOM   VDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGEL
CC	       **************************************************
CC	SEQRES GTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPD
CC	ATOM   GTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPD
CC	       **************************************************
CC	SEQRES DSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGID
CC	ATOM   DSLEPFFDSLVKQTHVPNLFSLQLCG------------SVGGSMIIGGID
CC	       **************************            ************
CC	SEQRES HSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSG
CC	ATOM   HSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSG
CC	       **************************************************
CC	SEQRES TTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIF
CC	ATOM   TTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIF
CC	       **************************************************
CC	SEQRES PVISLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSCG
CC	ATOM   PVISLYLMGEVTNQSFRITILPQQYLRPV--------DCYKFAISQSSCG
CC	       *****************************        *************
CC	SEQRES TVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDME
CC	ATOM   TVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDME
CC	       **************************************************
CC	SEQRES DCGYN
CC	ATOM   DCGYN
CC	       *****
SQ	SEQUENCE	405 AA;      MW;         CN;
	MLPRETDEEP EEPGRRGSFV EMVDNLRGKS GQGYYVEMTV GSPPQTLNIL VDTGSSNFAV
	GAAPHPFLHR YYQRQLSSTY RDLRKGVYVP YTQGKWEGEL GTDLVSIPHG PNVTVRANIA
	AITESDKFFI NGSNWEGILG LAYAEIARPD DSLEPFFDSL VKQTHVPNLF SLQLCGAGFP
	LNQSEVLASV GGSMIIGGID HSLYTGSLWY TPIRREWYYE VIIVRVEING QDLKMDCKEY
	NYDKSIVDSG TTNLRLPKKV FEAAVKSIKA ASSTEKFPDG FWLGEQLVCW QAGTTPWNIF
	PVISLYLMGE VTNQSFRITI LPQQYLRPVE DVATSQDDCY KFAISQSSCG TVMGAVIMEG
	FYVVFDRARK RIGFAVSACH VHDEFRTAAV EGPFVTLDME DCGYN
//