ID	2WXFA	STANDARD;	PRT;	940	AA.
DT	CONVERTED FROM PDB (SEQRES) 2WXF
DE	PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOF
DE	ORM
OS	MUS MUSCULUS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.211
FT	#HET	646	 750 	THR	A	1	1500 	039	A	S	1
FT	#HET	647	 751 	PHE	A	1	1500 	039	A	B	2
FT	#HET	648	 752 	MET	A	1	1500 	039	A	A	6
FT	#HET	654	 758 	PRO	A	1	1500 	039	A	A	5
FT	#HET	655	 759 	LEU	A	1	1500 	039	A	B	2
FT	#HET	656	 760 	TRP	A	1	1500 	039	A	A	11
FT	#HET	673	 777 	ILE	A	1	1500 	039	A	S	7
FT	#HET	709	 813 	TYR	A	1	1500 	039	A	S	4
FT	#HET	721	 825 	ILE	A	1	1500 	039	A	S	3
FT	#HET	722	 826 	GLU	A	1	1500 	039	A	B	4
FT	#HET	723	 827 	VAL	A	1	1500 	039	A	B	2
FT	#HET	724	 828 	VAL	A	1	1500 	039	A	A	8
FT	#HET	727	 831 	SER	A	1	1500 	039	A	B	1
FT	#HET	728	 832 	ASP	A	1	1500 	039	A	S	2
FT	#HET	729	 833 	THR	A	1	1500 	039	A	S	3
FT	#HET	732	 836 	ASN	A	1	1500 	039	A	S	2
FT	#HET	796	 900 	MET	A	1	1500 	039	A	S	7
FT	#HET	806	 910 	ILE	A	1	1500 	039	A	S	2
FT	DISORDER	1	4
FT	DISORDER	70	82
FT	DISORDER	127	130
FT	DISORDER	188	211
FT	DISORDER	232	234
FT	DISORDER	295	310
FT	DISORDER	342	347
FT	DISORDER	376	377
FT	DISORDER	391	406
FT	DISORDER	414	417
FT	DISORDER	816	824
FT	DISORDER	924	940
CC	SEQUENCE	822 AA (ATOM);
CC	VKKLINSQIS LLIGKGLHEF DSLRDPEVND FRTKMRQFCE EAAAHRQQLG WVEWLQYSFP
CC	LQLEPNRALL VNVKFEGSEE SFTFQVSTKD MPLALMACAL RKKATVFRQQ PEEYALQVNG
CC	RHEYLYGNYP LCHFQYICSC LHSGLTPHLT MVHSSSILAM RDEQSNLWSL EQPFSIELIE
CC	GRKVNAMKLV VQAGLFHGNE MLCKTVSSSE VNVCSEPVWK QRLEFDISVC DLPRMARLCF
CC	ALYAVVDCPI AWANLMLFDY KDQLKTGERC LYMWPSVLLN PAGTVRGNPN TESAAALVIY
CC	LPEVAPVYFP ALEKILELLR EILERELYEH EKDLVWKMRH EVQEHFPEAL ARLLLVTKWN
CC	KHEDVAQMLY LLCSWPELPV LSALELLDFS FPDCYVGSFA IKSLRKLTDD ELFQYLLQLV
CC	QVLKYESYLD CELTKFLLGR ALANRKIGHF LFWHLRSEMH VPSVALRFGL IMEAYCRGST
CC	HHMKVLMKQG EALSKLKALN DFVKVSSQKT TKPQTKEMMH MCMRQETYME ALSHLQSPLD
CC	PSTLLEEVCV EQCTFMDSKM KPLWIMYSSE EAGSAGNVGI IFKNGDDLRQ DMLTLQMIQL
CC	MDVLWKQEGL DLRMTPYGCL PTGDRTGLIE VVLHSDTIAN IQLNKSNMAA TAAFNKDALL
CC	NWLKSKNPGE ALDRAIEEFT LSCAGYCVAT YVLGIGDRHS DNIMIRESGQ LFHIDFGHFL
CC	GNFRVPFILT YDFVHVIQQG KTNNSEKFER FRGYCERAYT ILRRHGLLFL HLFALMRAAG
CC	LPELSCSKDI QYLKDSLALG KTEEEALKHF RVKFNEALRE SW
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES GGDRVKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHR
CC	ATOM   ----VKKLINSQISLLIGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHR
CC	           **********************************************
CC	SEQRES QQLGWVEWLQYSFPLQLEPSARGWRAGLLRVSNRALLVNVKFEGSEESFT
CC	ATOM   QQLGWVEWLQYSFPLQLEP-------------NRALLVNVKFEGSEESFT
CC	       *******************             ******************
CC	SEQRES FQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYALQVNGRHEYLYGNY
CC	ATOM   FQVSTKDMPLALMACALRKKATVFRQ----QPEEYALQVNGRHEYLYGNY
CC	       **************************    ********************
CC	SEQRES PLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPRAKPP
CC	ATOM   PLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSN-------------
CC	       *************************************             
CC	SEQRES PIPAKKPSSVSLWSLEQPFSIELIEGRKVNADERMKLVVQAGLFHGNEML
CC	ATOM   -----------LWSLEQPFSIELIEGRKVNA---MKLVVQAGLFHGNEML
CC	                  ********************   ****************
CC	SEQRES CKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKA
CC	ATOM   CKTVSSSEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVV------
CC	       ********************************************      
CC	SEQRES RSTKKKSKKADCPIAWANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLN
CC	ATOM   ----------DCPIAWANLMLFDYKDQLKTGERCLYMWPSV------LLN
CC	                 *******************************      ***
CC	SEQRES PAGTVRGNPNTESAAALVIYLPEVAPHPVYFPALEKILELGRHGERGRIT
CC	ATOM   PAGTVRGNPNTESAAALVIYLPEVA--PVYFPALEKILEL----------
CC	       *************************  *************          
CC	SEQRES EEEQLQLREILERRGSGELYEHEKDLVWKMRHEVQEHFPEALARLLLVTK
CC	ATOM   ------LREILER----ELYEHEKDLVWKMRHEVQEHFPEALARLLLVTK
CC	             *******    *********************************
CC	SEQRES WNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLT
CC	ATOM   WNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAIKSLRKLT
CC	       **************************************************
CC	SEQRES DDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSE
CC	ATOM   DDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSE
CC	       **************************************************
CC	SEQRES MHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQ
CC	ATOM   MHVPSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQ
CC	       **************************************************
CC	SEQRES KTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDS
CC	ATOM   KTTKPQTKEMMHMCMRQETYMEALSHLQSPLDPSTLLEEVCVEQCTFMDS
CC	       **************************************************
CC	SEQRES KMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQE
CC	ATOM   KMKPLWIMYSSEEAGSAGNVGIIFKNGDDLRQDMLTLQMIQLMDVLWKQE
CC	       **************************************************
CC	SEQRES GLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDA
CC	ATOM   GLDLRMTPYGCLPTGDRTGLIEVVLHSDTIANIQLNKSNMAATAAFNKDA
CC	       **************************************************
CC	SEQRES LLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
CC	ATOM   LLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
CC	       **************************************************
CC	SEQRES GQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFE
CC	ATOM   GQLFHIDFGHFLGNF---------RVPFILTYDFVHVIQQGKTNNSEKFE
CC	       ***************         **************************
CC	SEQRES RFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLAL
CC	ATOM   RFRGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLAL
CC	       **************************************************
CC	SEQRES GKTEEEALKHFRVKFNEALRESWKTKVNWLAHNVSKDNRQ
CC	ATOM   GKTEEEALKHFRVKFNEALRESW-----------------
CC	       ***********************                 
SQ	SEQUENCE	940 AA;      MW;         CN;
	GGDRVKKLIN SQISLLIGKG LHEFDSLRDP EVNDFRTKMR QFCEEAAAHR QQLGWVEWLQ
	YSFPLQLEPS ARGWRAGLLR VSNRALLVNV KFEGSEESFT FQVSTKDMPL ALMACALRKK
	ATVFRQPLVE QPEEYALQVN GRHEYLYGNY PLCHFQYICS CLHSGLTPHL TMVHSSSILA
	MRDEQSNPAP QVQKPRAKPP PIPAKKPSSV SLWSLEQPFS IELIEGRKVN ADERMKLVVQ
	AGLFHGNEML CKTVSSSEVN VCSEPVWKQR LEFDISVCDL PRMARLCFAL YAVVEKAKKA
	RSTKKKSKKA DCPIAWANLM LFDYKDQLKT GERCLYMWPS VPDEKGELLN PAGTVRGNPN
	TESAAALVIY LPEVAPHPVY FPALEKILEL GRHGERGRIT EEEQLQLREI LERRGSGELY
	EHEKDLVWKM RHEVQEHFPE ALARLLLVTK WNKHEDVAQM LYLLCSWPEL PVLSALELLD
	FSFPDCYVGS FAIKSLRKLT DDELFQYLLQ LVQVLKYESY LDCELTKFLL GRALANRKIG
	HFLFWHLRSE MHVPSVALRF GLIMEAYCRG STHHMKVLMK QGEALSKLKA LNDFVKVSSQ
	KTTKPQTKEM MHMCMRQETY MEALSHLQSP LDPSTLLEEV CVEQCTFMDS KMKPLWIMYS
	SEEAGSAGNV GIIFKNGDDL RQDMLTLQMI QLMDVLWKQE GLDLRMTPYG CLPTGDRTGL
	IEVVLHSDTI ANIQLNKSNM AATAAFNKDA LLNWLKSKNP GEALDRAIEE FTLSCAGYCV
	ATYVLGIGDR HSDNIMIRES GQLFHIDFGH FLGNFKTKFG INRERVPFIL TYDFVHVIQQ
	GKTNNSEKFE RFRGYCERAY TILRRHGLLF LHLFALMRAA GLPELSCSKD IQYLKDSLAL
	GKTEEEALKH FRVKFNEALR ESWKTKVNWL AHNVSKDNRQ
//