ID	2VNNA	STANDARD;	PRT;	392	AA.
DT	CONVERTED FROM PDB (SEQRES) 2VNN
DE	BETA-SECRETASE 1
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.870
CC	R-Factor	0.174
FT	#HET	12	  72 	GLY	A	1	2000 	CM7	A	B	4
FT	#HET	13	  73 	GLN	A	1	2000 	CM7	A	B	1
FT	#HET	14	  74 	GLY	A	1	2000 	CM7	A	B	1
FT	#HET	31	  91 	LEU	A	1	2000 	CM7	A	S	3
FT	#HET	33	  93 	ASP	A	1	2000 	CM7	A	S	9
FT	#HET	35	  95 	GLY	A	1	2000 	CM7	A	B	8
FT	#HET	36	  96 	SER	A	1	2000 	CM7	A	S	3
FT	#HET	70	 130 	VAL	A	1	2000 	CM7	A	S	1
FT	#HET	71	 131 	PRO	A	1	2000 	CM7	A	B	2
FT	#HET	72	 132 	TYR	A	1	2000 	CM7	A	A	14
FT	#HET	73	 133 	THR	A	1	2000 	CM7	A	A	9
FT	#HET	74	 134 	GLN	A	1	2000 	CM7	A	A	25
FT	#HET	109	 169 	PHE	A	1	2000 	CM7	A	A	4
FT	#HET	111	 171 	ILE	A	1	2000 	CM7	A	S	1
FT	#HET	116	 176 	TRP	A	1	2000 	CM7	A	S	3
FT	#HET	119	 179 	ILE	A	1	2000 	CM7	A	S	2
FT	#HET	127	 187 	ILE	A	1	2000 	CM7	A	A	2
FT	#HET	129	 189 	ARG	A	1	2000 	CM7	A	S	2
FT	#HET	199	 259 	TYR	A	1	2000 	CM7	A	S	6
FT	#HET	229	 289 	ASP	A	1	2000 	CM7	A	S	7
FT	#HET	231	 291 	GLY	A	1	2000 	CM7	A	B	10
FT	#HET	232	 292 	THR	A	1	2000 	CM7	A	S	6
FT	#HET	233	 293 	THR	A	1	2000 	CM7	A	A	8
FT	#HET	234	 294 	ASN	A	1	2000 	CM7	A	A	14
FT	#HET	236	 296 	ARG	A	1	2000 	CM7	A	S	3
FT	#HET	326	 386 	SER	A	1	2000 	CM7	A	S	1
FT	DISORDER	1	1
FT	DISORDER	158	168
FT	DISORDER	388	392
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	374 AA (ATOM);
CC	EMVDNLRGKS GQGYYVEMTV GSPPQTLNIL VDTGSSNFAV GAAPHPFLHR YYQRQLSSTY
CC	RDLRKGVYVP YTQGKWEGEL GTDLVSIPHG PQVTVRANIA AITESDKFFI QGSNWEGILG
CC	LAYAEIARPD DSLEPFFDSL VKQTHVPNLF SLQLCGASVG GSMIIGGIDH SLYTGSLWYT
CC	PIRREWYYEV IIVRVEINGQ DLKMDCKEYN YDKSIVDSGT TNLRLPKKVF EAAVKSIKAA
CC	SSTEKFPDGF WLGEQLVCWQ AGTTPWNIFP VISLYLMGEV TQQSFRITIL PQQYLRPVED
CC	VATSQDDCYK FAISQSSTGT VMGAVIMEGF YVVFDRARKR IGFAVSACHV HDEFRTAAVE
CC	GPFVTLDMED CGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLH
CC	ATOM   -EMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLH
CC	        *************************************************
CC	SEQRES RYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPQVTVRANI
CC	ATOM   RYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPQVTVRANI
CC	       **************************************************
CC	SEQRES AAITESDKFFIQGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNL
CC	ATOM   AAITESDKFFIQGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNL
CC	       **************************************************
CC	SEQRES FSLQLCGAGFPLQQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYY
CC	ATOM   FSLQLCG-----------ASVGGSMIIGGIDHSLYTGSLWYTPIRREWYY
CC	       *******           ********************************
CC	SEQRES EVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK
CC	ATOM   EVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIK
CC	       **************************************************
CC	SEQRES AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTQQSFRIT
CC	ATOM   AASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTQQSFRIT
CC	       **************************************************
CC	SEQRES ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAR
CC	ATOM   ILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRAR
CC	       **************************************************
CC	SEQRES KRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIPQTDE
CC	ATOM   KRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI-----
CC	       *************************************     
SQ	SEQUENCE	392 AA;      MW;         CN;
	VEMVDNLRGK SGQGYYVEMT VGSPPQTLNI LVDTGSSNFA VGAAPHPFLH RYYQRQLSST
	YRDLRKGVYV PYTQGKWEGE LGTDLVSIPH GPQVTVRANI AAITESDKFF IQGSNWEGIL
	GLAYAEIARP DDSLEPFFDS LVKQTHVPNL FSLQLCGAGF PLQQSEVLAS VGGSMIIGGI
	DHSLYTGSLW YTPIRREWYY EVIIVRVEIN GQDLKMDCKE YNYDKSIVDS GTTNLRLPKK
	VFEAAVKSIK AASSTEKFPD GFWLGEQLVC WQAGTTPWNI FPVISLYLMG EVTQQSFRIT
	ILPQQYLRPV EDVATSQDDC YKFAISQSST GTVMGAVIME GFYVVFDRAR KRIGFAVSAC
	HVHDEFRTAA VEGPFVTLDM EDCGYNIPQT DE
//