ID	2VA7A	STANDARD;	PRT;	455	AA.
DT	CONVERTED FROM PDB (SEQRES) 2VA7
DE	BETA-SECRETASE 1 .
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.200
CC	R-Factor	0.226
FT	#HET	73	  10 	SER	A	4	1505 	C27	A	B	2
FT	#HET	74	  11 	GLY	A	4	1505 	C27	A	B	4
FT	#HET	75	  12 	GLN	A	4	1505 	C27	A	B	2
FT	#HET	76	  13 	GLY	A	4	1505 	C27	A	B	7
FT	#HET	93	  30 	LEU	A	4	1505 	C27	A	S	4
FT	#HET	95	  32 	ASP	A	4	1505 	C27	A	S	12
FT	#HET	97	  34 	GLY	A	4	1505 	C27	A	B	3
FT	#HET	98	  35 	SER	A	4	1505 	C27	A	S	2
FT	#HET	108	  45 	HIS	A	1	1502 	IOD	A	S	2
FT	#HET	108	  45 	HIS	A	2	1503 	IOD	A	S	1
FT	#HET	134	  71 	TYR	A	4	1505 	C27	A	S	6
FT	#HET	166	 103 	THR	A	1	1502 	IOD	A	B	2
FT	#HET	167	 104 	GLU	A	1	1502 	IOD	A	B	3
FT	#HET	168	 105 	SER	A	1	1502 	IOD	A	A	2
FT	#HET	169	 106 	ASP	A	2	1503 	IOD	A	A	2
FT	#HET	170	 107 	LYS	A	2	1503 	IOD	A	B	1
FT	#HET	171	 108 	PHE	A	4	1505 	C27	A	A	3
FT	#HET	173	 110 	ILE	A	4	1505 	C27	A	S	1
FT	#HET	178	 115 	TRP	A	4	1505 	C27	A	S	3
FT	#HET	291	 228 	ASP	A	4	1505 	C27	A	S	5
FT	#HET	292	 229 	SER	A	4	1505 	C27	A	B	2
FT	#HET	293	 230 	GLY	A	4	1505 	C27	A	B	12
FT	#HET	294	 231 	THR	A	4	1505 	C27	A	S	1
FT	#HET	295	 232 	THR	A	4	1505 	C27	A	S	2
FT	#HET	398	 335 	ALA	A	4	1505 	C27	A	S	1
FT	#HET	412	 349 	ARG	A	3	1504 	IOD	A	S	2
FT	DISORDER	1	61
FT	DISORDER	221	233
FT	DISORDER	450	455
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	375 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAG GSMIIGGIDH SLYTGSLWYT
CC	PIRREWYYEV IIVRVEINGQ DLKMDCKEYN YDKSIVDSGT TNLRLPKKVF EAAVKSIKAA
CC	SSTEKFPDGF WLGEQLVCWQ AGTTPWNIFP VISLYLMGEV TNQSFRITIL PQQYLRPVED
CC	VATSQDDCYK FAISQSSTGT VMGAVIMEGF YVVFDRARKR IGFAVSACHV HDEFRTAAVE
CC	GPFVTLDMED CGYNI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MASMTGGQQMGRGSMAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETD
CC	ATOM   --------------------------------------------------
CC	                                                         
CC	SEQRES EEPEEPGKKGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSN
CC	ATOM   -----------FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSN
CC	                  ***************************************
CC	SEQRES FAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI
CC	ATOM   FAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI
CC	       **************************************************
CC	SEQRES PHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFF
CC	ATOM   PHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFF
CC	       **************************************************
CC	SEQRES DSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGS
CC	ATOM   DSLVKQTHVPNLFSLQLCGA-------------GGSMIIGGIDHSLYTGS
CC	       ********************             *****************
CC	SEQRES LWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP
CC	ATOM   LWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP
CC	       **************************************************
CC	SEQRES KKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYL
CC	ATOM   KKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYL
CC	       **************************************************
CC	SEQRES MGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVI
CC	ATOM   MGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVI
CC	       **************************************************
CC	SEQRES MEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIP
CC	ATOM   MEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI-
CC	       ************************************************* 
CC	SEQRES QTDES
CC	ATOM   -----
CC	            
SQ	SEQUENCE	455 AA;      MW;         CN;
	MASMTGGQQM GRGSMAGVLP AHGTQHGIRL PLRSGLGGAP LGLRLPRETD EEPEEPGKKG
	SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN FAVGAAPHPF LHRYYQRQLS
	STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA NIAAITESDK FFINGSNWEG
	ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA GFPLNQSEVL ASVGGSMIIG
	GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC KEYNYDKSIV DSGTTNLRLP
	KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW NIFPVISLYL MGEVTNQSFR
	ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI MEGFYVVFDR ARKRIGFAVS
	ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDES
//