ID	2VA5A	STANDARD;	PRT;	455	AA.
DT	CONVERTED FROM PDB (SEQRES) 2VA5
DE	BETA-SECRETASE 1 .
OS	HOMO SAPIENS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.750
CC	R-Factor	0.232
FT	#HET	74	  11 	GLY	A	3	1389 	C8C	A	B	1
FT	#HET	93	  30 	LEU	A	3	1389 	C8C	A	S	2
FT	#HET	95	  32 	ASP	A	3	1389 	C8C	A	S	10
FT	#HET	97	  34 	GLY	A	3	1389 	C8C	A	B	1
FT	#HET	108	  45 	HIS	A	1	1387 	IOD	A	S	1
FT	#HET	134	  71 	TYR	A	3	1389 	C8C	A	S	1
FT	#HET	166	 103 	THR	A	1	1387 	IOD	A	B	2
FT	#HET	167	 104 	GLU	A	1	1387 	IOD	A	B	3
FT	#HET	168	 105 	SER	A	1	1387 	IOD	A	A	2
FT	#HET	170	 107 	LYS	A	2	1388 	IOD	A	B	1
FT	#HET	171	 108 	PHE	A	3	1389 	C8C	A	S	1
FT	#HET	173	 110 	ILE	A	3	1389 	C8C	A	S	1
FT	#HET	181	 118 	ILE	A	3	1389 	C8C	A	S	2
FT	#HET	291	 228 	ASP	A	3	1389 	C8C	A	S	4
FT	#HET	293	 230 	GLY	A	3	1389 	C8C	A	B	6
FT	DISORDER	1	61
FT	DISORDER	221	230
FT	DISORDER	450	455
CC	Miss-BB	1
CC	Miss-SC	1
CC	SEQUENCE	378 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAA SVGGSMIIGG IDHSLYTGSL
CC	WYTPIRREWY YEVIIVRVEI NGQDLKMDCK EYNYDKSIVD SGTTNLRLPK KVFEAAVKSI
CC	KAASSTEKFP DGFWLGEQLV CWQAGTTPWN IFPVISLYLM GEVTNQSFRI TILPQQYLRP
CC	VEDVATSQDD CYKFAISQSS TGTVMGAVIM EGFYVVFDRA RKRIGFAVSA CHVHDEFRTA
CC	AVEGPFVTLD MEDCGYNI
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MASMTGGQQMGRGSMAGVLPAHGTQHGIRLPLRSGLGGAPLGLRLPRETD
CC	ATOM   --------------------------------------------------
CC	                                                         
CC	SEQRES EEPEEPGKKGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSN
CC	ATOM   -----------FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSN
CC	                  ***************************************
CC	SEQRES FAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI
CC	ATOM   FAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSI
CC	       **************************************************
CC	SEQRES PHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFF
CC	ATOM   PHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFF
CC	       **************************************************
CC	SEQRES DSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGS
CC	ATOM   DSLVKQTHVPNLFSLQLCGA----------ASVGGSMIIGGIDHSLYTGS
CC	       ********************          ********************
CC	SEQRES LWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP
CC	ATOM   LWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLP
CC	       **************************************************
CC	SEQRES KKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYL
CC	ATOM   KKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYL
CC	       **************************************************
CC	SEQRES MGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVI
CC	ATOM   MGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVI
CC	       **************************************************
CC	SEQRES MEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNIP
CC	ATOM   MEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCGYNI-
CC	       ************************************************* 
CC	SEQRES QTDES
CC	ATOM   -----
CC	            
SQ	SEQUENCE	455 AA;      MW;         CN;
	MASMTGGQQM GRGSMAGVLP AHGTQHGIRL PLRSGLGGAP LGLRLPRETD EEPEEPGKKG
	SFVEMVDNLR GKSGQGYYVE MTVGSPPQTL NILVDTGSSN FAVGAAPHPF LHRYYQRQLS
	STYRDLRKGV YVPYTQGKWE GELGTDLVSI PHGPNVTVRA NIAAITESDK FFINGSNWEG
	ILGLAYAEIA RPDDSLEPFF DSLVKQTHVP NLFSLQLCGA GFPLNQSEVL ASVGGSMIIG
	GIDHSLYTGS LWYTPIRREW YYEVIIVRVE INGQDLKMDC KEYNYDKSIV DSGTTNLRLP
	KKVFEAAVKS IKAASSTEKF PDGFWLGEQL VCWQAGTTPW NIFPVISLYL MGEVTNQSFR
	ITILPQQYLR PVEDVATSQD DCYKFAISQS STGTVMGAVI MEGFYVVFDR ARKRIGFAVS
	ACHVHDEFRT AAVEGPFVTL DMEDCGYNIP QTDES
//