ID	2Q9FA	STANDARD;	PRT;	456	AA.
DT	CONVERTED FROM PDB (SEQRES) 2Q9F
DE	Cytochrome P450 46A1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	1.900
CC	R-Factor	0.183
FT	#HET	19	  67 	TRP	A	5	932 	GOL	A	S	6
FT	#HET	30	  78 	ASN	A	6	933 	GOL	A	A	15
FT	#HET	32	  80 	PHE	A	3	600 	C3S	A	A	6
FT	#HET	32	  80 	PHE	A	6	933 	GOL	A	B	4
FT	#HET	33	  81 	HIS	A	3	600 	C3S	A	A	9
FT	#HET	34	  82 	LYS	A	6	933 	GOL	A	B	2
FT	#HET	35	  83 	THR	A	6	933 	GOL	A	A	8
FT	#HET	43	  91 	GLU	A	4	931 	GOL	A	A	2
FT	#HET	44	  92 	SER	A	4	931 	GOL	A	A	7
FT	#HET	47	  95 	LYS	A	4	931 	GOL	A	S	1
FT	#HET	56	 104 	LYS	A	2	602 	HEM	A	S	5
FT	#HET	60	 108 	MET	A	3	600 	C3S	A	A	4
FT	#HET	61	 109 	TYR	A	2	602 	HEM	A	S	5
FT	#HET	61	 109 	TYR	A	3	600 	C3S	A	S	4
FT	#HET	62	 110 	ARG	A	3	600 	C3S	A	S	4
FT	#HET	63	 111 	ALA	A	3	600 	C3S	A	S	1
FT	#HET	73	 121 	PHE	A	3	600 	C3S	A	S	1
FT	#HET	77	 125 	LEU	A	2	602 	HEM	A	A	8
FT	#HET	78	 126 	VAL	A	2	602 	HEM	A	A	4
FT	#HET	78	 126 	VAL	A	3	600 	C3S	A	S	2
FT	#HET	86	 134 	TRP	A	2	602 	HEM	A	S	7
FT	#HET	90	 138 	ARG	A	2	602 	HEM	A	S	5
FT	#HET	97	 145 	PHE	A	2	602 	HEM	A	S	2
FT	#HET	119	 167 	ILE	A	8	935 	GOL	A	S	1
FT	#HET	123	 171 	LYS	A	9	936 	GOL	A	S	1
FT	#HET	130	 178 	VAL	A	9	936 	GOL	A	S	1
FT	#HET	131	 179 	SER	A	9	936 	GOL	A	A	3
FT	#HET	134	 182 	ASP	A	9	936 	GOL	A	S	3
FT	#HET	135	 183 	MET	A	8	935 	GOL	A	S	2
FT	#HET	138	 186 	TYR	A	8	935 	GOL	A	S	1
FT	#HET	138	 186 	TYR	A	9	936 	GOL	A	S	1
FT	#HET	144	 192 	LEU	A	2	602 	HEM	A	S	1
FT	#HET	149	 197 	PHE	A	1	601 	PO4	A	B	2
FT	#HET	150	 198 	GLY	A	1	601 	PO4	A	B	2
FT	#HET	151	 199 	MET	A	1	601 	PO4	A	S	1
FT	#HET	155	 203 	MET	A	8	935 	GOL	A	B	1
FT	#HET	156	 204 	LEU	A	8	935 	GOL	A	B	4
FT	#HET	158	 206 	GLY	A	8	935 	GOL	A	B	1
FT	#HET	161	 209 	LYS	A	8	935 	GOL	A	S	2
FT	#HET	174	 222 	ILE	A	3	600 	C3S	A	B	2
FT	#HET	177	 225 	SER	A	3	600 	C3S	A	B	1
FT	#HET	178	 226 	ARG	A	3	600 	C3S	A	A	5
FT	#HET	179	 227 	ASN	A	3	600 	C3S	A	A	4
FT	#HET	213	 261 	ARG	A	1	601 	PO4	A	A	12
FT	#HET	251	 299 	PHE	A	2	602 	HEM	A	S	2
FT	#HET	254	 302 	ALA	A	2	602 	HEM	A	A	9
FT	#HET	254	 302 	ALA	A	3	600 	C3S	A	A	2
FT	#HET	255	 303 	GLY	A	2	602 	HEM	A	B	5
FT	#HET	258	 306 	THR	A	2	602 	HEM	A	A	11
FT	#HET	259	 307 	SER	A	2	602 	HEM	A	A	4
FT	#HET	262	 310 	HIS	A	2	602 	HEM	A	S	1
FT	#HET	319	 367 	ALA	A	2	602 	HEM	A	S	3
FT	#HET	319	 367 	ALA	A	3	600 	C3S	A	S	1
FT	#HET	320	 368 	TRP	A	3	600 	C3S	A	S	5
FT	#HET	321	 369 	GLY	A	3	600 	C3S	A	B	2
FT	#HET	322	 370 	THR	A	2	602 	HEM	A	A	6
FT	#HET	323	 371 	PHE	A	3	600 	C3S	A	S	2
FT	#HET	332	 380 	ILE	A	4	931 	GOL	A	B	2
FT	#HET	333	 381 	ASP	A	4	931 	GOL	A	A	3
FT	#HET	375	 423 	PRO	A	7	934 	GOL	A	B	1
FT	#HET	376	 424 	ARG	A	7	934 	GOL	A	B	2
FT	#HET	377	 425 	PHE	A	7	934 	GOL	A	A	7
FT	#HET	381	 429 	PRO	A	2	602 	HEM	A	B	3
FT	#HET	382	 430 	PHE	A	2	602 	HEM	A	A	13
FT	#HET	383	 431 	SER	A	2	602 	HEM	A	A	2
FT	#HET	384	 432 	LEU	A	7	934 	GOL	A	S	2
FT	#HET	387	 435 	ARG	A	2	602 	HEM	A	A	6
FT	#HET	388	 436 	SER	A	2	602 	HEM	A	B	1
FT	#HET	389	 437 	CYS	A	2	602 	HEM	A	A	19
FT	#HET	390	 438 	ILE	A	2	602 	HEM	A	S	2
FT	#HET	391	 439 	GLY	A	2	602 	HEM	A	B	5
FT	#HET	394	 442 	PHE	A	2	602 	HEM	A	S	5
FT	#HET	395	 443 	ALA	A	2	602 	HEM	A	S	4
FT	#HET	398	 446 	GLU	A	2	602 	HEM	A	S	1
FT	#HET	426	 474 	ALA	A	3	600 	C3S	A	B	4
FT	#HET	427	 475 	THR	A	3	600 	C3S	A	S	1
FT	DISORDER	1	10
FT	DISORDER	444	456
CC	SEQUENCE	433 AA (ATOM);
CC	VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM YRALQTVFGE
CC	RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL EAKADGQTPV
CC	SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT LAKFLPGKRK
CC	QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD DEGLLDNFVT
CC	FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG RLQYLSQVLK
CC	ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP LTFNPDRFGP
CC	GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF GLQEQATLKP
CC	LDPVLCTLRP RGW
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKDEVGGRVLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	ATOM   ----------VLQDVFLDWAKKYGPVVRVNVFHKTSVIVTSPESVKKFLM
CC	                 ****************************************
CC	SEQRES STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	ATOM   STKYNKDSKMYRALQTVFGERLFGQGLVSECNYERWHKQRRVIDLAFSRS
CC	       **************************************************
CC	SEQRES SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	ATOM   SLVSLMETFNEKAEQLVEILEAKADGQTPVSMQDMLTYTAMDILAKAAFG
CC	       **************************************************
CC	SEQRES METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	ATOM   METSMLLGAQKPLSQAVKLMLEGITASRNTLAKFLPGKRKQLREVRESIR
CC	       **************************************************
CC	SEQRES FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	ATOM   FLRQVGRDWVQRRREALKRGEEVPADILTQILKAEEGAQDDEGLLDNFVT
CC	       **************************************************
CC	SEQRES FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	ATOM   FFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSKRYLDFEDLG
CC	       **************************************************
CC	SEQRES RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	ATOM   RLQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVM
CC	       **************************************************
CC	SEQRES GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	ATOM   GRMDTYFEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVK
CC	       **************************************************
CC	SEQRES VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGWQPAPPPP
CC	ATOM   VVMAKLLQRLEFRLVPGQRFGLQEQATLKPLDPVLCTLRPRGW-------
CC	       *******************************************       
CC	SEQRES PCHHHH
CC	ATOM   ------
CC	             
SQ	SEQUENCE	456 AA;      MW;         CN;
	MAKKDEVGGR VLQDVFLDWA KKYGPVVRVN VFHKTSVIVT SPESVKKFLM STKYNKDSKM
	YRALQTVFGE RLFGQGLVSE CNYERWHKQR RVIDLAFSRS SLVSLMETFN EKAEQLVEIL
	EAKADGQTPV SMQDMLTYTA MDILAKAAFG METSMLLGAQ KPLSQAVKLM LEGITASRNT
	LAKFLPGKRK QLREVRESIR FLRQVGRDWV QRRREALKRG EEVPADILTQ ILKAEEGAQD
	DEGLLDNFVT FFIAGHETSA NHLAFTVMEL SRQPEIVARL QAEVDEVIGS KRYLDFEDLG
	RLQYLSQVLK ESLRLYPPAW GTFRLLEEET LIDGVRVPGN TPLLFSTYVM GRMDTYFEDP
	LTFNPDRFGP GAPKPRFTYF PFSLGHRSCI GQQFAQMEVK VVMAKLLQRL EFRLVPGQRF
	GLQEQATLKP LDPVLCTLRP RGWQPAPPPP PCHHHH
//