ID	2OHSA	STANDARD;	PRT;	402	AA.
DT	CONVERTED FROM PDB (SEQRES) 2OHS
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.185
FT	#HET	27	  10 	SER	A	4	389 	9IP	A	B	7
FT	#HET	28	  11 	GLY	A	4	389 	9IP	A	B	4
FT	#HET	29	  12 	GLN	A	4	389 	9IP	A	B	5
FT	#HET	30	  13 	GLY	A	4	389 	9IP	A	B	10
FT	#HET	47	  30 	LEU	A	4	389 	9IP	A	S	7
FT	#HET	49	  32 	ASP	A	4	389 	9IP	A	S	15
FT	#HET	51	  34 	GLY	A	4	389 	9IP	A	B	11
FT	#HET	52	  35 	SER	A	4	389 	9IP	A	S	1
FT	#HET	62	  45 	HIS	A	1	386 	IOD	A	S	1
FT	#HET	62	  45 	HIS	A	2	387 	IOD	A	S	1
FT	#HET	88	  71 	TYR	A	4	389 	9IP	A	S	9
FT	#HET	99	  82 	THR	A	3	388 	DMS	A	S	1
FT	#HET	113	  96 	ARG	A	3	388 	DMS	A	A	6
FT	#HET	115	  98 	ASN	A	3	388 	DMS	A	A	4
FT	#HET	121	 104 	GLU	A	1	386 	IOD	A	B	3
FT	#HET	122	 105 	SER	A	1	386 	IOD	A	A	2
FT	#HET	124	 107 	LYS	A	2	387 	IOD	A	B	1
FT	#HET	125	 108 	PHE	A	4	389 	9IP	A	A	16
FT	#HET	126	 109 	PHE	A	1	386 	IOD	A	S	1
FT	#HET	127	 110 	ILE	A	4	389 	9IP	A	S	5
FT	#HET	132	 115 	TRP	A	4	389 	9IP	A	S	3
FT	#HET	135	 118 	ILE	A	4	389 	9IP	A	S	4
FT	#HET	245	 228 	ASP	A	4	389 	9IP	A	S	17
FT	#HET	246	 229 	SER	A	4	389 	9IP	A	B	4
FT	#HET	247	 230 	GLY	A	4	389 	9IP	A	B	32
FT	#HET	248	 231 	THR	A	4	389 	9IP	A	A	16
FT	#HET	249	 232 	THR	A	4	389 	9IP	A	A	9
FT	#HET	352	 335 	ALA	A	4	389 	9IP	A	S	1
FT	DISORDER	1	15
FT	DISORDER	175	187
CC	SEQUENCE	374 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAG GSMIIGGIDH SLYTGSLWYT
CC	PIRREWYYEV IIVRVEINGQ DLKMDCKEYN YDKSIVDSGT TNLRLPKKVF EAAVKSIKAA
CC	SSTEKFPDGF WLGEQLVCWQ AGTTPWNIFP VISLYLMGEV TNQSFRITIL PQQYLRPVED
CC	VATSQDDCYK FAISQSSTGT VMGAVIMEGF YVVFDRARKR IGFAVSACHV HDEFRTAAVE
CC	GPFVTLDMED CGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RETDEEPEEPGKKGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDT
CC	ATOM   ---------------FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDT
CC	                      ***********************************
CC	SEQRES GSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTD
CC	ATOM   GSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTD
CC	       **************************************************
CC	SEQRES LVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSL
CC	ATOM   LVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSL
CC	       **************************************************
CC	SEQRES EPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSL
CC	ATOM   EPFFDSLVKQTHVPNLFSLQLCGA-------------GGSMIIGGIDHSL
CC	       ************************             *************
CC	SEQRES YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTN
CC	ATOM   YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTN
CC	       **************************************************
CC	SEQRES LRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
CC	ATOM   LRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
CC	       **************************************************
CC	SEQRES SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM
CC	ATOM   SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM
CC	       **************************************************
CC	SEQRES GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCG
CC	ATOM   GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCG
CC	       **************************************************
CC	SEQRES YN
CC	ATOM   YN
CC	       **
SQ	SEQUENCE	402 AA;      MW;         CN;
	RETDEEPEEP GKKGSFVEMV DNLRGKSGQG YYVEMTVGSP PQTLNILVDT GSSNFAVGAA
	PHPFLHRYYQ RQLSSTYRDL RKGVYVPYTQ GKWEGELGTD LVSIPHGPNV TVRANIAAIT
	ESDKFFINGS NWEGILGLAY AEIARPDDSL EPFFDSLVKQ THVPNLFSLQ LCGAGFPLNQ
	SEVLASVGGS MIIGGIDHSL YTGSLWYTPI RREWYYEVII VRVEINGQDL KMDCKEYNYD
	KSIVDSGTTN LRLPKKVFEA AVKSIKAASS TEKFPDGFWL GEQLVCWQAG TTPWNIFPVI
	SLYLMGEVTN QSFRITILPQ QYLRPVEDVA TSQDDCYKFA ISQSSTGTVM GAVIMEGFYV
	VFDRARKRIG FAVSACHVHD EFRTAAVEGP FVTLDMEDCG YN
//