ID	2OF0A	STANDARD;	PRT;	402	AA.
DT	CONVERTED FROM PDB (SEQRES) 2OF0
DE	Beta-secretase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.250
CC	R-Factor	0.223
FT	#HET	47	  30 	LEU	A	5	390 	CMZ	A	S	1
FT	#HET	49	  32 	ASP	A	5	390 	CMZ	A	S	7
FT	#HET	51	  34 	GLY	A	5	390 	CMZ	A	B	4
FT	#HET	62	  45 	HIS	A	2	387 	IOD	A	S	1
FT	#HET	88	  71 	TYR	A	5	390 	CMZ	A	S	4
FT	#HET	99	  82 	THR	A	4	389 	DMS	A	S	1
FT	#HET	113	  96 	ARG	A	4	389 	DMS	A	A	5
FT	#HET	115	  98 	ASN	A	4	389 	DMS	A	A	4
FT	#HET	120	 103 	THR	A	1	386 	IOD	A	B	2
FT	#HET	121	 104 	GLU	A	1	386 	IOD	A	B	3
FT	#HET	122	 105 	SER	A	1	386 	IOD	A	A	2
FT	#HET	124	 107 	LYS	A	2	387 	IOD	A	B	1
FT	#HET	125	 108 	PHE	A	5	390 	CMZ	A	A	4
FT	#HET	132	 115 	TRP	A	5	390 	CMZ	A	S	2
FT	#HET	151	 134 	GLU	A	4	389 	DMS	A	S	2
FT	#HET	160	 143 	GLN	A	4	389 	DMS	A	S	2
FT	#HET	215	 198 	TYR	A	5	390 	CMZ	A	S	1
FT	#HET	243	 226 	ILE	A	5	390 	CMZ	A	S	2
FT	#HET	245	 228 	ASP	A	5	390 	CMZ	A	S	10
FT	#HET	247	 230 	GLY	A	5	390 	CMZ	A	B	1
FT	#HET	248	 231 	THR	A	5	390 	CMZ	A	S	3
FT	#HET	349	 332 	VAL	A	5	390 	CMZ	A	S	1
FT	#HET	366	 349 	ARG	A	3	388 	IOD	A	S	2
FT	DISORDER	1	15
FT	DISORDER	175	184
CC	SEQUENCE	377 AA (ATOM);
CC	FVEMVDNLRG KSGQGYYVEM TVGSPPQTLN ILVDTGSSNF AVGAAPHPFL HRYYQRQLSS
CC	TYRDLRKGVY VPYTQGKWEG ELGTDLVSIP HGPNVTVRAN IAAITESDKF FINGSNWEGI
CC	LGLAYAEIAR PDDSLEPFFD SLVKQTHVPN LFSLQLCGAA SVGGSMIIGG IDHSLYTGSL
CC	WYTPIRREWY YEVIIVRVEI NGQDLKMDCK EYNYDKSIVD SGTTNLRLPK KVFEAAVKSI
CC	KAASSTEKFP DGFWLGEQLV CWQAGTTPWN IFPVISLYLM GEVTNQSFRI TILPQQYLRP
CC	VEDVATSQDD CYKFAISQSS TGTVMGAVIM EGFYVVFDRA RKRIGFAVSA CHVHDEFRTA
CC	AVEGPFVTLD MEDCGYN
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES RETDEEPEEPGKKGSFVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDT
CC	ATOM   ---------------FVEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDT
CC	                      ***********************************
CC	SEQRES GSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTD
CC	ATOM   GSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTD
CC	       **************************************************
CC	SEQRES LVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSL
CC	ATOM   LVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSL
CC	       **************************************************
CC	SEQRES EPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSL
CC	ATOM   EPFFDSLVKQTHVPNLFSLQLCGA----------ASVGGSMIIGGIDHSL
CC	       ************************          ****************
CC	SEQRES YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTN
CC	ATOM   YTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTN
CC	       **************************************************
CC	SEQRES LRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
CC	ATOM   LRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVI
CC	       **************************************************
CC	SEQRES SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM
CC	ATOM   SLYLMGEVTNQSFRITILPQQYLRPVEDVATSQDDCYKFAISQSSTGTVM
CC	       **************************************************
CC	SEQRES GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCG
CC	ATOM   GAVIMEGFYVVFDRARKRIGFAVSACHVHDEFRTAAVEGPFVTLDMEDCG
CC	       **************************************************
CC	SEQRES YN
CC	ATOM   YN
CC	       **
SQ	SEQUENCE	402 AA;      MW;         CN;
	RETDEEPEEP GKKGSFVEMV DNLRGKSGQG YYVEMTVGSP PQTLNILVDT GSSNFAVGAA
	PHPFLHRYYQ RQLSSTYRDL RKGVYVPYTQ GKWEGELGTD LVSIPHGPNV TVRANIAAIT
	ESDKFFINGS NWEGILGLAY AEIARPDDSL EPFFDSLVKQ THVPNLFSLQ LCGAGFPLNQ
	SEVLASVGGS MIIGGIDHSL YTGSLWYTPI RREWYYEVII VRVEINGQDL KMDCKEYNYD
	KSIVDSGTTN LRLPKKVFEA AVKSIKAASS TEKFPDGFWL GEQLVCWQAG TTPWNIFPVI
	SLYLMGEVTN QSFRITILPQ QYLRPVEDVA TSQDDCYKFA ISQSSTGTVM GAVIMEGFYV
	VFDRARKRIG FAVSACHVHD EFRTAAVEGP FVTLDMEDCG YN
//