ID	2DQZA	STANDARD;	PRT;	542	AA.
DT	CONVERTED FROM PDB (SEQRES) 2DQZ
DE	Liver carboxylesterase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.193
FT	#SUB	40	1058 	PRO	A	166	2184 	HIS	B	Protein	S	1
FT	#SUB	40	1058 	PRO	A	262	2280 	ALA	B	Protein	S	1
FT	#SUB	42	1060 	LEU	A	262	2280 	ALA	B	Protein	S	1
FT	#SUB	43	1061 	GLY	A	266	2284 	HIS	B	Protein	B	2
FT	#SUB	54	1072 	GLU	A	165	2183 	GLU	B	Protein	B	2
FT	#SUB	55	1073 	PRO	A	165	2183 	GLU	B	Protein	B	1
FT	#SUB	55	1073 	PRO	A	168	2186 	ARG	B	Protein	B	3
FT	#SUB	56	1074 	TRP	A	165	2183 	GLU	B	Protein	A	4
FT	#SUB	56	1074 	TRP	A	168	2186 	ARG	B	Protein	B	2
FT	#SUB	57	1075 	SER	A	168	2186 	ARG	B	Protein	A	4
FT	#SUB	57	1075 	SER	A	306	2324 	ASP	B	Protein	S	2
FT	#SUB	57	1075 	SER	A	307	2325 	GLY	B	Protein	S	3
FT	#SUB	58	1076 	PHE	A	305	2323 	ILE	B	Protein	S	2
FT	#SUB	58	1076 	PHE	A	306	2324 	ASP	B	Protein	S	2
FT	#SUB	58	1076 	PHE	A	307	2325 	GLY	B	Protein	S	4
FT	#SUB	58	1076 	PHE	A	311	2329 	LEU	B	Protein	S	1
FT	#SUB	60	1078 	LYS	A	165	2183 	GLU	B	Protein	S	3
FT	#SUB	95	1113 	SER	A	263	2281 	VAL	B	Protein	S	1
FT	#SUB	97	1115 	ASP	A	260	2278 	THR	B	Protein	S	4
FT	#SUB	97	1115 	ASP	A	262	2280 	ALA	B	Protein	S	1
FT	#SUB	273	1291 	GLU	A	257	2275 	LYS	B	Protein	S	1
FT	#SUB	165	1183 	GLU	A	54	3072 	GLU	C	Protein	S	1
FT	#SUB	165	1183 	GLU	A	55	3073 	PRO	C	Protein	S	1
FT	#SUB	165	1183 	GLU	A	56	3074 	TRP	C	Protein	S	1
FT	#SUB	165	1183 	GLU	A	60	3078 	LYS	C	Protein	S	3
FT	#SUB	166	1184 	HIS	A	40	3058 	PRO	C	Protein	S	1
FT	#SUB	168	1186 	ARG	A	55	3073 	PRO	C	Protein	S	3
FT	#SUB	168	1186 	ARG	A	56	3074 	TRP	C	Protein	S	2
FT	#SUB	168	1186 	ARG	A	57	3075 	SER	C	Protein	S	4
FT	#SUB	259	1277 	THR	A	94	3112 	LEU	C	Protein	S	1
FT	#SUB	260	1278 	THR	A	67	3085 	PRO	C	Protein	S	1
FT	#SUB	260	1278 	THR	A	97	3115 	ASP	C	Protein	S	4
FT	#SUB	262	1280 	ALA	A	40	3058 	PRO	C	Protein	S	1
FT	#SUB	262	1280 	ALA	A	42	3060 	LEU	C	Protein	B	1
FT	#SUB	262	1280 	ALA	A	97	3115 	ASP	C	Protein	S	1
FT	#SUB	263	1281 	VAL	A	95	3113 	SER	C	Protein	S	1
FT	#SUB	266	1284 	HIS	A	42	3060 	LEU	C	Protein	S	2
FT	#SUB	266	1284 	HIS	A	43	3061 	GLY	C	Protein	S	2
FT	#SUB	305	1323 	ILE	A	58	3076 	PHE	C	Protein	A	3
FT	#SUB	306	1324 	ASP	A	57	3075 	SER	C	Protein	B	2
FT	#SUB	306	1324 	ASP	A	58	3076 	PHE	C	Protein	B	2
FT	#SUB	307	1325 	GLY	A	57	3075 	SER	C	Protein	B	4
FT	#SUB	307	1325 	GLY	A	58	3076 	PHE	C	Protein	B	3
FT	#SUB	311	1329 	LEU	A	58	3076 	PHE	C	Protein	B	1
FT	#HET	34	1052 	GLY	A	2	182 	SIA	A	B	5
FT	#HET	42	1060 	LEU	A	10	285 	SO4	B	B	1
FT	#HET	43	1061 	GLY	A	10	285 	SO4	B	B	2
FT	#HET	44	1062 	PRO	A	10	285 	SO4	B	S	1
FT	#HET	46	1064 	ARG	A	4	284 	SO4	A	S	2
FT	#HET	61	1079 	ASN	A	2	182 	SIA	A	A	15
FT	#HET	64	1082 	SER	A	2	182 	SIA	A	A	4
FT	#HET	66	1084 	PRO	A	2	182 	SIA	A	B	1
FT	#HET	75	1093 	ALA	A	6	111 	PLM	A	A	2
FT	#HET	96	1114 	GLU	A	4	284 	SO4	A	S	5
FT	#HET	123	1141 	GLY	A	5	4002 	F	A	B	2
FT	#HET	124	1142 	GLY	A	5	4002 	F	A	B	3
FT	#HET	124	1142 	GLY	A	6	111 	PLM	A	B	2
FT	#HET	125	1143 	GLY	A	5	4002 	F	A	B	2
FT	#HET	128	1146 	VAL	A	6	111 	PLM	A	S	1
FT	#HET	203	1221 	SER	A	5	4002 	F	A	A	3
FT	#HET	203	1221 	SER	A	6	111 	PLM	A	S	2
FT	#HET	204	1222 	ALA	A	5	4002 	F	A	A	3
FT	#HET	242	1260 	ASP	A	16	379 	NAG	C	S	4
FT	#HET	244	1262 	LYS	A	17	382 	SIA	C	S	5
FT	#HET	259	1277 	THR	A	17	382 	SIA	C	B	1
FT	#HET	266	1284 	HIS	A	3	184 	SO4	A	A	7
FT	#HET	266	1284 	HIS	A	18	185 	SO4	C	S	5
FT	#HET	269	1287 	ARG	A	3	184 	SO4	A	S	5
FT	#HET	270	1288 	GLN	A	3	184 	SO4	A	S	1
FT	#HET	271	1289 	LYS	A	4	284 	SO4	A	B	1
FT	#HET	272	1290 	THR	A	4	284 	SO4	A	A	5
FT	#HET	273	1291 	GLU	A	4	284 	SO4	A	A	5
FT	#HET	286	1304 	LEU	A	6	111 	PLM	A	S	3
FT	#HET	339	1357 	TRP	A	7	11 	HTQ	A	A	4
FT	#HET	343	1361 	MET	A	7	11 	HTQ	A	A	4
FT	#HET	344	1363 	LEU	A	6	111 	PLM	A	S	3
FT	#HET	347	1366 	TYR	A	7	11 	HTQ	A	B	2
FT	#HET	349	1368 	LEU	A	7	11 	HTQ	A	A	10
FT	#HET	395	1414 	LYS	A	7	11 	HTQ	A	S	3
FT	#HET	399	1418 	LEU	A	7	11 	HTQ	A	S	1
FT	#MOD	61	1079 	ASN	A	1	179 	NAG	A	S
FT	DISORDER	1	2
FT	DISORDER	535	542
CC	SEQUENCE	532 AA (ATOM);
CC	SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA
CC	TSYPPMCTQD PKAGQLLSEL FTNRKENIPL KLSEDCLYLN IYTPADLTKK NRLPVMVWIH
CC	GGGLMVGAAS TYDGLALAAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW
CC	VQDNIASFGG NPGSVTIFGE SAGGESVSVL VLSPLAKNLF HRAISESGVA LTSVLVKKGD
CC	VKPLAEQIAI TAGCKTTTSA VMVHCLRQKT EEELLETTLK MKFLSLDLQG DPRESQPLLG
CC	TVIDGMLLLK TPEELQAERN FHTVPYMVGI NKQEFGWLIP MLMSYPLSEG QLDQKTAMSL
CC	LWKSYPLVCI AKELIPEATE KYLGGTDDTV KKKDLFLDLI ADVMFGVPSV IVARNHRDAG
CC	APTYMYEFQY RPSFSSDMKP KTVIGDHGDE LFSVFGAPFL KEGASEEEIR LSKMVMKFWA
CC	NFARNGNPNG EGLPHWPEYN QKEGYLQIGA NTQAAQKLKD KEVAFWTNLF AK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	ATOM   --SSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	         ************************************************
CC	SEQRES QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	ATOM   QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	       **************************************************
CC	SEQRES LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	ATOM   LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	       **************************************************
CC	SEQRES QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	ATOM   QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	       **************************************************
CC	SEQRES GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	ATOM   GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	       **************************************************
CC	SEQRES AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	ATOM   AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	       **************************************************
CC	SEQRES LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	ATOM   LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	       **************************************************
CC	SEQRES EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	ATOM   EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	       **************************************************
CC	SEQRES LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	ATOM   LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	       **************************************************
CC	SEQRES DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	ATOM   DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	       **************************************************
CC	SEQRES YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQ
CC	ATOM   YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAK--------
CC	       **********************************        
SQ	SEQUENCE	542 AA;      MW;         CN;
	HPSSPPVVDT VHGKVLGKFV SLEGFAQPVA IFLGIPFAKP PLGPLRFTPP QPAEPWSFVK
	NATSYPPMCT QDPKAGQLLS ELFTNRKENI PLKLSEDCLY LNIYTPADLT KKNRLPVMVW
	IHGGGLMVGA ASTYDGLALA AHENVVVVTI QYRLGIWGFF STGDEHSRGN WGHLDQVAAL
	RWVQDNIASF GGNPGSVTIF GESAGGESVS VLVLSPLAKN LFHRAISESG VALTSVLVKK
	GDVKPLAEQI AITAGCKTTT SAVMVHCLRQ KTEEELLETT LKMKFLSLDL QGDPRESQPL
	LGTVIDGMLL LKTPEELQAE RNFHTVPYMV GINKQEFGWL IPMLMSYPLS EGQLDQKTAM
	SLLWKSYPLV CIAKELIPEA TEKYLGGTDD TVKKKDLFLD LIADVMFGVP SVIVARNHRD
	AGAPTYMYEF QYRPSFSSDM KPKTVIGDHG DELFSVFGAP FLKEGASEEE IRLSKMVMKF
	WANFARNGNP NGEGLPHWPE YNQKEGYLQI GANTQAAQKL KDKEVAFWTN LFAKKAVEKP
	PQ
//
ID	2DQZB	STANDARD;	PRT;	542	AA.
DT	CONVERTED FROM PDB (SEQRES) 2DQZ
DE	Liver carboxylesterase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.193
FT	#SUB	165	2183 	GLU	B	54	1072 	GLU	A	Protein	S	2
FT	#SUB	165	2183 	GLU	B	55	1073 	PRO	A	Protein	S	1
FT	#SUB	165	2183 	GLU	B	56	1074 	TRP	A	Protein	S	4
FT	#SUB	165	2183 	GLU	B	60	1078 	LYS	A	Protein	S	3
FT	#SUB	166	2184 	HIS	B	40	1058 	PRO	A	Protein	S	1
FT	#SUB	168	2186 	ARG	B	55	1073 	PRO	A	Protein	S	3
FT	#SUB	168	2186 	ARG	B	56	1074 	TRP	A	Protein	S	2
FT	#SUB	168	2186 	ARG	B	57	1075 	SER	A	Protein	S	4
FT	#SUB	257	2275 	LYS	B	273	1291 	GLU	A	Protein	S	1
FT	#SUB	260	2278 	THR	B	97	1115 	ASP	A	Protein	S	4
FT	#SUB	262	2280 	ALA	B	40	1058 	PRO	A	Protein	S	1
FT	#SUB	262	2280 	ALA	B	42	1060 	LEU	A	Protein	B	1
FT	#SUB	262	2280 	ALA	B	97	1115 	ASP	A	Protein	S	1
FT	#SUB	263	2281 	VAL	B	95	1113 	SER	A	Protein	S	1
FT	#SUB	266	2284 	HIS	B	43	1061 	GLY	A	Protein	S	2
FT	#SUB	305	2323 	ILE	B	58	1076 	PHE	A	Protein	B	2
FT	#SUB	306	2324 	ASP	B	57	1075 	SER	A	Protein	B	2
FT	#SUB	306	2324 	ASP	B	58	1076 	PHE	A	Protein	B	2
FT	#SUB	307	2325 	GLY	B	57	1075 	SER	A	Protein	B	3
FT	#SUB	307	2325 	GLY	B	58	1076 	PHE	A	Protein	B	4
FT	#SUB	311	2329 	LEU	B	58	1076 	PHE	A	Protein	B	1
FT	#SUB	40	2058 	PRO	B	166	3184 	HIS	C	Protein	S	1
FT	#SUB	40	2058 	PRO	B	262	3280 	ALA	C	Protein	S	1
FT	#SUB	42	2060 	LEU	B	262	3280 	ALA	C	Protein	S	1
FT	#SUB	42	2060 	LEU	B	266	3284 	HIS	C	Protein	S	3
FT	#SUB	43	2061 	GLY	B	266	3284 	HIS	C	Protein	B	3
FT	#SUB	54	2072 	GLU	B	165	3183 	GLU	C	Protein	B	2
FT	#SUB	55	2073 	PRO	B	165	3183 	GLU	C	Protein	B	2
FT	#SUB	55	2073 	PRO	B	168	3186 	ARG	C	Protein	B	2
FT	#SUB	56	2074 	TRP	B	165	3183 	GLU	C	Protein	A	5
FT	#SUB	56	2074 	TRP	B	168	3186 	ARG	C	Protein	B	1
FT	#SUB	57	2075 	SER	B	168	3186 	ARG	C	Protein	A	4
FT	#SUB	57	2075 	SER	B	306	3324 	ASP	C	Protein	S	2
FT	#SUB	57	2075 	SER	B	307	3325 	GLY	C	Protein	S	3
FT	#SUB	58	2076 	PHE	B	305	3323 	ILE	C	Protein	S	2
FT	#SUB	58	2076 	PHE	B	306	3324 	ASP	C	Protein	S	2
FT	#SUB	58	2076 	PHE	B	307	3325 	GLY	C	Protein	S	3
FT	#SUB	58	2076 	PHE	B	311	3329 	LEU	C	Protein	S	1
FT	#SUB	60	2078 	LYS	B	165	3183 	GLU	C	Protein	S	6
FT	#SUB	67	2085 	PRO	B	260	3278 	THR	C	Protein	S	1
FT	#SUB	93	2111 	LYS	B	259	3277 	THR	C	Protein	S	1
FT	#SUB	94	2112 	LEU	B	259	3277 	THR	C	Protein	B	1
FT	#SUB	95	2113 	SER	B	263	3281 	VAL	C	Protein	S	1
FT	#SUB	97	2115 	ASP	B	260	3278 	THR	C	Protein	S	4
FT	#SUB	97	2115 	ASP	B	262	3280 	ALA	C	Protein	S	1
FT	#SUB	273	2291 	GLU	B	257	3275 	LYS	C	Protein	S	1
FT	#HET	16	2034 	LEU	B	8	279 	NAG	B	S	1
FT	#HET	34	2052 	GLY	B	9	282 	SIA	B	B	5
FT	#HET	46	2064 	ARG	B	11	385 	SO4	B	S	1
FT	#HET	60	2078 	LYS	B	9	282 	SIA	B	A	4
FT	#HET	61	2079 	ASN	B	9	282 	SIA	B	A	23
FT	#HET	64	2082 	SER	B	9	282 	SIA	B	A	6
FT	#HET	75	2093 	ALA	B	14	112 	PLM	B	A	3
FT	#HET	96	2114 	GLU	B	11	385 	SO4	B	S	5
FT	#HET	123	2141 	GLY	B	13	4001 	F	B	B	2
FT	#HET	124	2142 	GLY	B	13	4001 	F	B	B	3
FT	#HET	124	2142 	GLY	B	14	112 	PLM	B	B	1
FT	#HET	125	2143 	GLY	B	13	4001 	F	B	B	2
FT	#HET	128	2146 	VAL	B	14	112 	PLM	B	S	1
FT	#HET	143	2161 	GLU	B	12	286 	SO4	B	S	1
FT	#HET	203	2221 	SER	B	13	4001 	F	B	A	4
FT	#HET	203	2221 	SER	B	14	112 	PLM	B	S	3
FT	#HET	204	2222 	ALA	B	13	4001 	F	B	A	3
FT	#HET	242	2260 	ASP	B	1	179 	NAG	A	S	3
FT	#HET	244	2262 	LYS	B	2	182 	SIA	A	S	2
FT	#HET	259	2277 	THR	B	2	182 	SIA	A	B	1
FT	#HET	266	2284 	HIS	B	4	284 	SO4	A	S	7
FT	#HET	266	2284 	HIS	B	10	285 	SO4	B	A	6
FT	#HET	269	2287 	ARG	B	10	285 	SO4	B	S	1
FT	#HET	272	2290 	THR	B	11	385 	SO4	B	A	4
FT	#HET	273	2291 	GLU	B	11	385 	SO4	B	B	3
FT	#HET	286	2304 	LEU	B	14	112 	PLM	B	S	3
FT	#HET	338	2356 	GLY	B	15	21 	HTQ	B	B	2
FT	#HET	339	2357 	TRP	B	15	21 	HTQ	B	S	2
FT	#HET	344	2363 	LEU	B	14	112 	PLM	B	S	4
FT	#HET	349	2368 	LEU	B	15	21 	HTQ	B	A	6
FT	#HET	350	2369 	SER	B	15	21 	HTQ	B	B	8
FT	#HET	351	2370 	GLU	B	15	21 	HTQ	B	B	2
FT	#HET	352	2371 	GLY	B	15	21 	HTQ	B	B	4
FT	#HET	395	2414 	LYS	B	15	21 	HTQ	B	S	3
FT	#HET	440	2459 	MET	B	15	21 	HTQ	B	A	2
FT	#HET	479	2498 	LYS	B	12	286 	SO4	B	S	1
FT	#MOD	61	2079 	ASN	B	8	279 	NAG	B	S
FT	DISORDER	1	2
FT	DISORDER	535	542
CC	SEQUENCE	532 AA (ATOM);
CC	SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA
CC	TSYPPMCTQD PKAGQLLSEL FTNRKENIPL KLSEDCLYLN IYTPADLTKK NRLPVMVWIH
CC	GGGLMVGAAS TYDGLALAAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW
CC	VQDNIASFGG NPGSVTIFGE SAGGESVSVL VLSPLAKNLF HRAISESGVA LTSVLVKKGD
CC	VKPLAEQIAI TAGCKTTTSA VMVHCLRQKT EEELLETTLK MKFLSLDLQG DPRESQPLLG
CC	TVIDGMLLLK TPEELQAERN FHTVPYMVGI NKQEFGWLIP MLMSYPLSEG QLDQKTAMSL
CC	LWKSYPLVCI AKELIPEATE KYLGGTDDTV KKKDLFLDLI ADVMFGVPSV IVARNHRDAG
CC	APTYMYEFQY RPSFSSDMKP KTVIGDHGDE LFSVFGAPFL KEGASEEEIR LSKMVMKFWA
CC	NFARNGNPNG EGLPHWPEYN QKEGYLQIGA NTQAAQKLKD KEVAFWTNLF AK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	ATOM   --SSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	         ************************************************
CC	SEQRES QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	ATOM   QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	       **************************************************
CC	SEQRES LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	ATOM   LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	       **************************************************
CC	SEQRES QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	ATOM   QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	       **************************************************
CC	SEQRES GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	ATOM   GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	       **************************************************
CC	SEQRES AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	ATOM   AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	       **************************************************
CC	SEQRES LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	ATOM   LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	       **************************************************
CC	SEQRES EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	ATOM   EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	       **************************************************
CC	SEQRES LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	ATOM   LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	       **************************************************
CC	SEQRES DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	ATOM   DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	       **************************************************
CC	SEQRES YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQ
CC	ATOM   YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAK--------
CC	       **********************************        
SQ	SEQUENCE	542 AA;      MW;         CN;
	HPSSPPVVDT VHGKVLGKFV SLEGFAQPVA IFLGIPFAKP PLGPLRFTPP QPAEPWSFVK
	NATSYPPMCT QDPKAGQLLS ELFTNRKENI PLKLSEDCLY LNIYTPADLT KKNRLPVMVW
	IHGGGLMVGA ASTYDGLALA AHENVVVVTI QYRLGIWGFF STGDEHSRGN WGHLDQVAAL
	RWVQDNIASF GGNPGSVTIF GESAGGESVS VLVLSPLAKN LFHRAISESG VALTSVLVKK
	GDVKPLAEQI AITAGCKTTT SAVMVHCLRQ KTEEELLETT LKMKFLSLDL QGDPRESQPL
	LGTVIDGMLL LKTPEELQAE RNFHTVPYMV GINKQEFGWL IPMLMSYPLS EGQLDQKTAM
	SLLWKSYPLV CIAKELIPEA TEKYLGGTDD TVKKKDLFLD LIADVMFGVP SVIVARNHRD
	AGAPTYMYEF QYRPSFSSDM KPKTVIGDHG DELFSVFGAP FLKEGASEEE IRLSKMVMKF
	WANFARNGNP NGEGLPHWPE YNQKEGYLQI GANTQAAQKL KDKEVAFWTN LFAKKAVEKP
	PQ
//
ID	2DQZC	STANDARD;	PRT;	542	AA.
DT	CONVERTED FROM PDB (SEQRES) 2DQZ
DE	Liver carboxylesterase 1
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.800
CC	R-Factor	0.193
FT	#SUB	40	3058 	PRO	C	166	1184 	HIS	A	Protein	S	1
FT	#SUB	40	3058 	PRO	C	262	1280 	ALA	A	Protein	S	1
FT	#SUB	42	3060 	LEU	C	262	1280 	ALA	A	Protein	S	1
FT	#SUB	42	3060 	LEU	C	266	1284 	HIS	A	Protein	S	2
FT	#SUB	43	3061 	GLY	C	266	1284 	HIS	A	Protein	B	2
FT	#SUB	54	3072 	GLU	C	165	1183 	GLU	A	Protein	B	1
FT	#SUB	55	3073 	PRO	C	165	1183 	GLU	A	Protein	B	1
FT	#SUB	55	3073 	PRO	C	168	1186 	ARG	A	Protein	B	3
FT	#SUB	56	3074 	TRP	C	165	1183 	GLU	A	Protein	S	1
FT	#SUB	56	3074 	TRP	C	168	1186 	ARG	A	Protein	B	2
FT	#SUB	57	3075 	SER	C	168	1186 	ARG	A	Protein	A	4
FT	#SUB	57	3075 	SER	C	306	1324 	ASP	A	Protein	S	2
FT	#SUB	57	3075 	SER	C	307	1325 	GLY	A	Protein	S	4
FT	#SUB	58	3076 	PHE	C	305	1323 	ILE	A	Protein	S	3
FT	#SUB	58	3076 	PHE	C	306	1324 	ASP	A	Protein	S	2
FT	#SUB	58	3076 	PHE	C	307	1325 	GLY	A	Protein	S	3
FT	#SUB	58	3076 	PHE	C	311	1329 	LEU	A	Protein	S	1
FT	#SUB	60	3078 	LYS	C	165	1183 	GLU	A	Protein	S	3
FT	#SUB	67	3085 	PRO	C	260	1278 	THR	A	Protein	S	1
FT	#SUB	94	3112 	LEU	C	259	1277 	THR	A	Protein	B	1
FT	#SUB	95	3113 	SER	C	263	1281 	VAL	A	Protein	S	1
FT	#SUB	97	3115 	ASP	C	260	1278 	THR	A	Protein	S	4
FT	#SUB	97	3115 	ASP	C	262	1280 	ALA	A	Protein	S	1
FT	#SUB	165	3183 	GLU	C	54	2072 	GLU	B	Protein	S	2
FT	#SUB	165	3183 	GLU	C	55	2073 	PRO	B	Protein	S	2
FT	#SUB	165	3183 	GLU	C	56	2074 	TRP	B	Protein	S	5
FT	#SUB	165	3183 	GLU	C	60	2078 	LYS	B	Protein	S	6
FT	#SUB	166	3184 	HIS	C	40	2058 	PRO	B	Protein	S	1
FT	#SUB	168	3186 	ARG	C	55	2073 	PRO	B	Protein	S	2
FT	#SUB	168	3186 	ARG	C	56	2074 	TRP	B	Protein	S	1
FT	#SUB	168	3186 	ARG	C	57	2075 	SER	B	Protein	S	4
FT	#SUB	257	3275 	LYS	C	273	2291 	GLU	B	Protein	S	1
FT	#SUB	259	3277 	THR	C	93	2111 	LYS	B	Protein	S	1
FT	#SUB	259	3277 	THR	C	94	2112 	LEU	B	Protein	S	1
FT	#SUB	260	3278 	THR	C	67	2085 	PRO	B	Protein	S	1
FT	#SUB	260	3278 	THR	C	97	2115 	ASP	B	Protein	S	4
FT	#SUB	262	3280 	ALA	C	40	2058 	PRO	B	Protein	S	1
FT	#SUB	262	3280 	ALA	C	42	2060 	LEU	B	Protein	B	1
FT	#SUB	262	3280 	ALA	C	97	2115 	ASP	B	Protein	S	1
FT	#SUB	263	3281 	VAL	C	95	2113 	SER	B	Protein	S	1
FT	#SUB	266	3284 	HIS	C	42	2060 	LEU	B	Protein	S	3
FT	#SUB	266	3284 	HIS	C	43	2061 	GLY	B	Protein	S	3
FT	#SUB	305	3323 	ILE	C	58	2076 	PHE	B	Protein	B	2
FT	#SUB	306	3324 	ASP	C	57	2075 	SER	B	Protein	B	2
FT	#SUB	306	3324 	ASP	C	58	2076 	PHE	B	Protein	B	2
FT	#SUB	307	3325 	GLY	C	57	2075 	SER	B	Protein	B	3
FT	#SUB	307	3325 	GLY	C	58	2076 	PHE	B	Protein	B	3
FT	#SUB	311	3329 	LEU	C	58	2076 	PHE	B	Protein	B	1
FT	#HET	34	3052 	GLY	C	17	382 	SIA	C	B	1
FT	#HET	42	3060 	LEU	C	3	184 	SO4	A	A	3
FT	#HET	43	3061 	GLY	C	3	184 	SO4	A	B	1
FT	#HET	46	3064 	ARG	C	18	185 	SO4	C	S	2
FT	#HET	60	3078 	LYS	C	17	382 	SIA	C	A	4
FT	#HET	61	3079 	ASN	C	17	382 	SIA	C	A	23
FT	#HET	96	3114 	GLU	C	18	185 	SO4	C	S	2
FT	#HET	100	3118 	TYR	C	17	382 	SIA	C	S	1
FT	#HET	123	3141 	GLY	C	20	4003 	F	C	B	2
FT	#HET	124	3142 	GLY	C	20	4003 	F	C	B	3
FT	#HET	125	3143 	GLY	C	20	4003 	F	C	B	2
FT	#HET	125	3143 	GLY	C	21	1 	COA	C	B	1
FT	#HET	203	3221 	SER	C	20	4003 	F	C	A	4
FT	#HET	203	3221 	SER	C	21	1 	COA	C	S	2
FT	#HET	204	3222 	ALA	C	20	4003 	F	C	A	3
FT	#HET	233	3251 	LEU	C	22	113 	PLM	C	B	2
FT	#HET	234	3252 	THR	C	22	113 	PLM	C	B	2
FT	#HET	235	3253 	SER	C	22	113 	PLM	C	A	12
FT	#HET	236	3254 	VAL	C	22	113 	PLM	C	B	1
FT	#HET	244	3262 	LYS	C	9	282 	SIA	B	S	2
FT	#HET	266	3284 	HIS	C	11	385 	SO4	B	S	5
FT	#HET	266	3284 	HIS	C	19	384 	SO4	C	A	6
FT	#HET	269	3287 	ARG	C	19	384 	SO4	C	S	8
FT	#HET	271	3289 	LYS	C	18	185 	SO4	C	B	2
FT	#HET	272	3290 	THR	C	18	185 	SO4	C	A	7
FT	#HET	273	3291 	GLU	C	18	185 	SO4	C	A	5
FT	#HET	338	3356 	GLY	C	23	31 	HTQ	C	B	8
FT	#HET	339	3357 	TRP	C	23	31 	HTQ	C	A	5
FT	#HET	344	3363 	LEU	C	21	1 	COA	C	S	1
FT	#HET	349	3368 	LEU	C	23	31 	HTQ	C	A	19
FT	#HET	350	3369 	SER	C	23	31 	HTQ	C	B	8
FT	#HET	352	3371 	GLY	C	23	31 	HTQ	C	B	2
FT	#HET	369	3388 	LEU	C	22	113 	PLM	C	B	3
FT	#HET	370	3389 	VAL	C	22	113 	PLM	C	B	3
FT	#HET	395	3414 	LYS	C	23	31 	HTQ	C	S	11
FT	#HET	396	3415 	ASP	C	23	31 	HTQ	C	S	1
FT	#HET	399	3418 	LEU	C	23	31 	HTQ	C	S	2
FT	#HET	405	3424 	VAL	C	22	113 	PLM	C	A	9
FT	#HET	406	3425 	MET	C	22	113 	PLM	C	B	1
FT	#HET	409	3428 	VAL	C	22	113 	PLM	C	S	1
FT	#HET	413	3432 	ILE	C	22	113 	PLM	C	S	3
FT	#HET	440	3459 	MET	C	23	31 	HTQ	C	B	1
FT	#HET	442	3461 	PRO	C	23	31 	HTQ	C	S	4
FT	#HET	445	3464 	VAL	C	23	31 	HTQ	C	S	3
FT	#HET	529	3548 	THR	C	22	113 	PLM	C	A	4
FT	#HET	532	3551 	PHE	C	22	113 	PLM	C	S	1
FT	#MOD	61	3079 	ASN	C	16	379 	NAG	C	S
FT	DISORDER	1	2
FT	DISORDER	535	542
CC	SEQUENCE	532 AA (ATOM);
CC	SSPPVVDTVH GKVLGKFVSL EGFAQPVAIF LGIPFAKPPL GPLRFTPPQP AEPWSFVKNA
CC	TSYPPMCTQD PKAGQLLSEL FTNRKENIPL KLSEDCLYLN IYTPADLTKK NRLPVMVWIH
CC	GGGLMVGAAS TYDGLALAAH ENVVVVTIQY RLGIWGFFST GDEHSRGNWG HLDQVAALRW
CC	VQDNIASFGG NPGSVTIFGE SAGGESVSVL VLSPLAKNLF HRAISESGVA LTSVLVKKGD
CC	VKPLAEQIAI TAGCKTTTSA VMVHCLRQKT EEELLETTLK MKFLSLDLQG DPRESQPLLG
CC	TVIDGMLLLK TPEELQAERN FHTVPYMVGI NKQEFGWLIP MLMSYPLSEG QLDQKTAMSL
CC	LWKSYPLVCI AKELIPEATE KYLGGTDDTV KKKDLFLDLI ADVMFGVPSV IVARNHRDAG
CC	APTYMYEFQY RPSFSSDMKP KTVIGDHGDE LFSVFGAPFL KEGASEEEIR LSKMVMKFWA
CC	NFARNGNPNG EGLPHWPEYN QKEGYLQIGA NTQAAQKLKD KEVAFWTNLF AK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES HPSSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	ATOM   --SSPPVVDTVHGKVLGKFVSLEGFAQPVAIFLGIPFAKPPLGPLRFTPP
CC	         ************************************************
CC	SEQRES QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	ATOM   QPAEPWSFVKNATSYPPMCTQDPKAGQLLSELFTNRKENIPLKLSEDCLY
CC	       **************************************************
CC	SEQRES LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	ATOM   LNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTI
CC	       **************************************************
CC	SEQRES QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	ATOM   QYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIF
CC	       **************************************************
CC	SEQRES GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	ATOM   GESAGGESVSVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQI
CC	       **************************************************
CC	SEQRES AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	ATOM   AITAGCKTTTSAVMVHCLRQKTEEELLETTLKMKFLSLDLQGDPRESQPL
CC	       **************************************************
CC	SEQRES LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	ATOM   LGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQEFGWLIPMLMSYPLS
CC	       **************************************************
CC	SEQRES EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	ATOM   EGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKKDLFLD
CC	       **************************************************
CC	SEQRES LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	ATOM   LIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHG
CC	       **************************************************
CC	SEQRES DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	ATOM   DELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEGLPHWPE
CC	       **************************************************
CC	SEQRES YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAKKAVEKPPQ
CC	ATOM   YNQKEGYLQIGANTQAAQKLKDKEVAFWTNLFAK--------
CC	       **********************************        
SQ	SEQUENCE	542 AA;      MW;         CN;
	HPSSPPVVDT VHGKVLGKFV SLEGFAQPVA IFLGIPFAKP PLGPLRFTPP QPAEPWSFVK
	NATSYPPMCT QDPKAGQLLS ELFTNRKENI PLKLSEDCLY LNIYTPADLT KKNRLPVMVW
	IHGGGLMVGA ASTYDGLALA AHENVVVVTI QYRLGIWGFF STGDEHSRGN WGHLDQVAAL
	RWVQDNIASF GGNPGSVTIF GESAGGESVS VLVLSPLAKN LFHRAISESG VALTSVLVKK
	GDVKPLAEQI AITAGCKTTT SAVMVHCLRQ KTEEELLETT LKMKFLSLDL QGDPRESQPL
	LGTVIDGMLL LKTPEELQAE RNFHTVPYMV GINKQEFGWL IPMLMSYPLS EGQLDQKTAM
	SLLWKSYPLV CIAKELIPEA TEKYLGGTDD TVKKKDLFLD LIADVMFGVP SVIVARNHRD
	AGAPTYMYEF QYRPSFSSDM KPKTVIGDHG DELFSVFGAP FLKEGASEEE IRLSKMVMKF
	WANFARNGNP NGEGLPHWPE YNQKEGYLQI GANTQAAQKL KDKEVAFWTN LFAKKAVEKP
	PQ
//