ID	2BRKA	STANDARD;	PRT;	536	AA.
DT	CONVERTED FROM PDB (SEQRES) 2BRK
DE	RNA-DIRECTED RNA POLYMERASE
OS	HEPATITIS C VIRUS
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.187
FT	#HET	37	  37 	VAL	A	3	1534 	CMF	A	S	2
FT	#HET	220	 220 	ASP	A	1	1532 	MN	A	S	3
FT	#HET	220	 220 	ASP	A	2	1533 	MN	A	S	3
FT	#HET	221	 221 	THR	A	1	1532 	MN	A	B	4
FT	#HET	318	 318 	ASP	A	1	1532 	MN	A	S	3
FT	#HET	318	 318 	ASP	A	2	1533 	MN	A	S	3
FT	#HET	319	 319 	ASP	A	2	1533 	MN	A	A	4
FT	#HET	392	 392 	LEU	A	3	1534 	CMF	A	A	4
FT	#HET	393	 393 	ALA	A	3	1534 	CMF	A	B	3
FT	#HET	395	 395 	ALA	A	3	1534 	CMF	A	A	3
FT	#HET	396	 396 	ALA	A	3	1534 	CMF	A	S	6
FT	#HET	424	 424 	ILE	A	3	1534 	CMF	A	S	1
FT	#HET	425	 425 	LEU	A	3	1534 	CMF	A	S	2
FT	#HET	428	 428 	HIS	A	3	1534 	CMF	A	S	8
FT	#HET	429	 429 	PHE	A	3	1534 	CMF	A	S	2
FT	#HET	492	 492 	LEU	A	3	1534 	CMF	A	A	3
FT	#HET	493	 493 	GLY	A	3	1534 	CMF	A	B	4
FT	#HET	494	 494 	VAL	A	3	1534 	CMF	A	S	5
FT	#HET	495	 495 	PRO	A	3	1534 	CMF	A	S	8
FT	#HET	500	 500 	TRP	A	3	1534 	CMF	A	S	3
FT	#HET	503	 503 	ARG	A	3	1534 	CMF	A	S	6
FT	DISORDER	22	35
FT	DISORDER	148	152
FT	DISORDER	532	536
CC	SEQUENCE	512 AA (ATOM);
CC	SMSYTWTGAL ITPCAAEESK LMVYATTSRS AGLRQKKVTF DRLQVLDDHY RDVLKEMKAK
CC	ASTVKAKLLS VEEACKLTPP HSAKSKFGYG AKDVRNLSSK AVNHIHSVWK DLLEDTVTPI
CC	DTTIMAKNEV FCVGRKPARL IVFPDLGVRV CEKMALYDVV STLPQVVMGS SYGFQYSPGQ
CC	RVEFLVNTWK SKKNPMGFSY DTRCFDSTVT ENDIRVEESI YQCCDLAPEA RQAIKSLTER
CC	LYIGGPLTNS KGQNCGYRRC RASGVLTTSC GNTLTCYLKA SAACRAAKLQ DCTMLVNGDD
CC	LVVICESAGT QEDAASLRVF TEAMTRYSAP PGDPPQPEYD LELITSCSSN VSVAHDASGK
CC	RVYYLTRDPT TPLARAAWET ARHTPVNSWL GNIIMYAPTL WARMILMTHF FSILLAQEQL
CC	EKALDCQIYG ACYSIEPLDL PQIIERLHGL SAFSLHSYSP GEINRVASCL RKLGVPPLRV
CC	WRHRARSVRA RLLSQGGRAA TCGKYLFNWA VK
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES SMSYTWTGALITPCAAEESKLPINALSNSLLRHHNMVYATTSRSAGLRQK
CC	ATOM   SMSYTWTGALITPCAAEESKL--------------MVYATTSRSAGLRQK
CC	       *********************              ***************
CC	SEQRES KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	ATOM   KVTFDRLQVLDDHYRDVLKEMKAKASTVKAKLLSVEEACKLTPPHSAKSK
CC	       **************************************************
CC	SEQRES FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCVQPE
CC	ATOM   FGYGAKDVRNLSSKAVNHIHSVWKDLLEDTVTPIDTTIMAKNEVFCV---
CC	       ***********************************************   
CC	SEQRES KGGRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	ATOM   --GRKPARLIVFPDLGVRVCEKMALYDVVSTLPQVVMGSSYGFQYSPGQR
CC	         ************************************************
CC	SEQRES VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	ATOM   VEFLVNTWKSKKNPMGFSYDTRCFDSTVTENDIRVEESIYQCCDLAPEAR
CC	       **************************************************
CC	SEQRES QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	ATOM   QAIKSLTERLYIGGPLTNSKGQNCGYRRCRASGVLTTSCGNTLTCYLKAS
CC	       **************************************************
CC	SEQRES AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	ATOM   AACRAAKLQDCTMLVNGDDLVVICESAGTQEDAASLRVFTEAMTRYSAPP
CC	       **************************************************
CC	SEQRES GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	ATOM   GDPPQPEYDLELITSCSSNVSVAHDASGKRVYYLTRDPTTPLARAAWETA
CC	       **************************************************
CC	SEQRES RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	ATOM   RHTPVNSWLGNIIMYAPTLWARMILMTHFFSILLAQEQLEKALDCQIYGA
CC	       **************************************************
CC	SEQRES CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	ATOM   CYSIEPLDLPQIIERLHGLSAFSLHSYSPGEINRVASCLRKLGVPPLRVW
CC	       **************************************************
CC	SEQRES RHRARSVRARLLSQGGRAATCGKYLFNWAVKTKLKL
CC	ATOM   RHRARSVRARLLSQGGRAATCGKYLFNWAVK-----
CC	       *******************************     
SQ	SEQUENCE	536 AA;      MW;         CN;
	SMSYTWTGAL ITPCAAEESK LPINALSNSL LRHHNMVYAT TSRSAGLRQK KVTFDRLQVL
	DDHYRDVLKE MKAKASTVKA KLLSVEEACK LTPPHSAKSK FGYGAKDVRN LSSKAVNHIH
	SVWKDLLEDT VTPIDTTIMA KNEVFCVQPE KGGRKPARLI VFPDLGVRVC EKMALYDVVS
	TLPQVVMGSS YGFQYSPGQR VEFLVNTWKS KKNPMGFSYD TRCFDSTVTE NDIRVEESIY
	QCCDLAPEAR QAIKSLTERL YIGGPLTNSK GQNCGYRRCR ASGVLTTSCG NTLTCYLKAS
	AACRAAKLQD CTMLVNGDDL VVICESAGTQ EDAASLRVFT EAMTRYSAPP GDPPQPEYDL
	ELITSCSSNV SVAHDASGKR VYYLTRDPTT PLARAAWETA RHTPVNSWLG NIIMYAPTLW
	ARMILMTHFF SILLAQEQLE KALDCQIYGA CYSIEPLDLP QIIERLHGLS AFSLHSYSPG
	EINRVASCLR KLGVPPLRVW RHRARSVRAR LLSQGGRAAT CGKYLFNWAV KTKLKL
//