ID	1XLZA	STANDARD;	PRT;	398	AA.
DT	CONVERTED FROM PDB (SEQRES) 1XLZ
DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4B
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.060
CC	R-Factor	0.210
FT	#SUB	162	 292 	GLU	A	183	 313 	LYS	B	Protein	S	4
FT	#SUB	162	 292 	GLU	A	186	 316 	GLN	B	Protein	S	4
FT	#SUB	164	 294 	ALA	A	205	 335 	ARG	B	Protein	B	2
FT	#SUB	165	 295 	LEU	A	179	 309 	ALA	B	Protein	B	2
FT	#SUB	165	 295 	LEU	A	186	 316 	GLN	B	Protein	S	1
FT	#SUB	165	 295 	LEU	A	205	 335 	ARG	B	Protein	A	4
FT	#SUB	166	 296 	MET	A	166	 296 	MET	B	Protein	S	5
FT	#SUB	166	 296 	MET	A	167	 297 	TYR	B	Protein	A	5
FT	#SUB	166	 296 	MET	A	179	 309 	ALA	B	Protein	B	1
FT	#SUB	167	 297 	TYR	A	166	 296 	MET	B	Protein	S	5
FT	#SUB	167	 297 	TYR	A	167	 297 	TYR	B	Protein	S	4
FT	#SUB	168	 298 	ASN	A	175	 305 	ASN	B	Protein	S	7
FT	#SUB	168	 298 	ASN	A	178	 308 	LEU	B	Protein	S	8
FT	#SUB	168	 298 	ASN	A	179	 309 	ALA	B	Protein	S	1
FT	#SUB	168	 298 	ASN	A	205	 335 	ARG	B	Protein	B	2
FT	#SUB	168	 298 	ASN	A	209	 339 	ILE	B	Protein	A	2
FT	#SUB	169	 299 	ASP	A	205	 335 	ARG	B	Protein	A	11
FT	#SUB	175	 305 	ASN	A	168	 298 	ASN	B	Protein	A	7
FT	#SUB	178	 308 	LEU	A	168	 298 	ASN	B	Protein	A	6
FT	#SUB	179	 309 	ALA	A	165	 295 	LEU	B	Protein	A	2
FT	#SUB	179	 309 	ALA	A	166	 296 	MET	B	Protein	S	1
FT	#SUB	179	 309 	ALA	A	168	 298 	ASN	B	Protein	B	1
FT	#SUB	183	 313 	LYS	A	162	 292 	GLU	B	Protein	S	4
FT	#SUB	186	 316 	GLN	A	165	 295 	LEU	B	Protein	S	3
FT	#SUB	205	 335 	ARG	A	164	 294 	ALA	B	Protein	S	2
FT	#SUB	205	 335 	ARG	A	165	 295 	LEU	B	Protein	S	4
FT	#SUB	205	 335 	ARG	A	168	 298 	ASN	B	Protein	S	2
FT	#SUB	205	 335 	ARG	A	169	 299 	ASP	B	Protein	S	11
FT	#SUB	209	 339 	ILE	A	168	 298 	ASN	B	Protein	S	2
FT	#HET	103	 233 	TYR	A	3	1003 	FIL	A	S	3
FT	#HET	108	 238 	HIS	A	1	1001 	ZN	A	S	3
FT	#HET	144	 274 	HIS	A	1	1001 	ZN	A	S	3
FT	#HET	145	 275 	ASP	A	1	1001 	ZN	A	S	3
FT	#HET	145	 275 	ASP	A	2	1002 	MG	A	S	3
FT	#HET	217	 347 	MET	A	3	1003 	FIL	A	S	2
FT	#HET	262	 392 	ASP	A	1	1001 	ZN	A	S	3
FT	#HET	265	 395 	ASN	A	3	1003 	FIL	A	S	2
FT	#HET	277	 407 	THR	A	3	1003 	FIL	A	A	3
FT	#HET	280	 410 	ILE	A	3	1003 	FIL	A	S	6
FT	#HET	281	 411 	MET	A	3	1003 	FIL	A	S	2
FT	#HET	284	 414 	PHE	A	3	1003 	FIL	A	S	4
FT	#HET	301	 431 	MET	A	3	1003 	FIL	A	S	2
FT	#HET	312	 442 	SER	A	3	1003 	FIL	A	A	4
FT	#HET	313	 443 	GLN	A	3	1003 	FIL	A	S	9
FT	#HET	316	 446 	PHE	A	3	1003 	FIL	A	S	18
FT	DISORDER	1	32
FT	DISORDER	356	398
CC	SEQUENCE	323 AA (ATOM);
CC	EDHLAKELED LNKWGLNIFN VAGYSHNRPL TXIMYAIFQE RDLLKTFRIS SDTFITYMMT
CC	LEDHYHSDVA YHNSLHAADV AQSTHVLLST PALDAVFTDL EILAAIFAAA IHDVDHPGVS
CC	NQFLINTNSE LALMYNDESV LENHHLAVGF KLLQEEHXDI FMNLTKKQRQ TLRKMVIDMV
CC	LATDMSKHMS LLADLKTMVE TKKVTSSGVL LLDNYTDRIQ VLRNMVHCAD LSNPTKSLEL
CC	YRQWTDRIME EFFQQGDKER ERGMEISPMC DKHTASVEKS QVGFIDYIVH PLWETWADLV
CC	QPDAQDILDT LEDNRNWYQS MIP
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHMSISRFGVNTENEDHLAKELEDLNKWGLNI
CC	ATOM   --------------------------------EDHLAKELEDLNKWGLNI
CC	                                       ******************
CC	SEQRES FNVAGYSHNRPLTXIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	ATOM   FNVAGYSHNRPLTXIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	       **************************************************
CC	SEQRES VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	ATOM   VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	       **************************************************
CC	SEQRES VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHXDIFMNLTKKQ
CC	ATOM   VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHXDIFMNLTKKQ
CC	       **************************************************
CC	SEQRES RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	ATOM   RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	       **************************************************
CC	SEQRES IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	ATOM   IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	       **************************************************
CC	SEQRES MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	ATOM   MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	       **************************************************
CC	SEQRES QSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHS
CC	ATOM   QSMIP-------------------------------------------
CC	       *****                                           
SQ	SEQUENCE	398 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH MSISRFGVNT ENEDHLAKEL EDLNKWGLNI FNVAGYSHNR
	PLTXIMYAIF QERDLLKTFR ISSDTFITYM MTLEDHYHSD VAYHNSLHAA DVAQSTHVLL
	STPALDAVFT DLEILAAIFA AAIHDVDHPG VSNQFLINTN SELALMYNDE SVLENHHLAV
	GFKLLQEEHX DIFMNLTKKQ RQTLRKMVID MVLATDMSKH MSLLADLKTM VETKKVTSSG
	VLLLDNYTDR IQVLRNMVHC ADLSNPTKSL ELYRQWTDRI MEEFFQQGDK ERERGMEISP
	MCDKHTASVE KSQVGFIDYI VHPLWETWAD LVQPDAQDIL DTLEDNRNWY QSMIPQSPSP
	PLDEQNRDCQ GLMEKFQFEL TLDEEDSEGP EKEGEGHS
//
ID	1XLZB	STANDARD;	PRT;	398	AA.
DT	CONVERTED FROM PDB (SEQRES) 1XLZ
DE	cAMP-specific 3',5'-cyclic phosphodiesterase 4B
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.060
CC	R-Factor	0.210
FT	#SUB	162	 292 	GLU	B	183	 313 	LYS	A	Protein	S	4
FT	#SUB	164	 294 	ALA	B	205	 335 	ARG	A	Protein	B	2
FT	#SUB	165	 295 	LEU	B	179	 309 	ALA	A	Protein	B	2
FT	#SUB	165	 295 	LEU	B	186	 316 	GLN	A	Protein	S	3
FT	#SUB	165	 295 	LEU	B	205	 335 	ARG	A	Protein	A	4
FT	#SUB	166	 296 	MET	B	166	 296 	MET	A	Protein	S	5
FT	#SUB	166	 296 	MET	B	167	 297 	TYR	A	Protein	A	5
FT	#SUB	166	 296 	MET	B	179	 309 	ALA	A	Protein	B	1
FT	#SUB	167	 297 	TYR	B	166	 296 	MET	A	Protein	S	5
FT	#SUB	167	 297 	TYR	B	167	 297 	TYR	A	Protein	S	4
FT	#SUB	168	 298 	ASN	B	175	 305 	ASN	A	Protein	S	7
FT	#SUB	168	 298 	ASN	B	178	 308 	LEU	A	Protein	S	6
FT	#SUB	168	 298 	ASN	B	179	 309 	ALA	A	Protein	S	1
FT	#SUB	168	 298 	ASN	B	205	 335 	ARG	A	Protein	B	2
FT	#SUB	168	 298 	ASN	B	209	 339 	ILE	A	Protein	A	2
FT	#SUB	169	 299 	ASP	B	205	 335 	ARG	A	Protein	A	11
FT	#SUB	175	 305 	ASN	B	168	 298 	ASN	A	Protein	A	7
FT	#SUB	178	 308 	LEU	B	168	 298 	ASN	A	Protein	A	8
FT	#SUB	179	 309 	ALA	B	165	 295 	LEU	A	Protein	A	2
FT	#SUB	179	 309 	ALA	B	166	 296 	MET	A	Protein	S	1
FT	#SUB	179	 309 	ALA	B	168	 298 	ASN	A	Protein	B	1
FT	#SUB	183	 313 	LYS	B	162	 292 	GLU	A	Protein	S	4
FT	#SUB	186	 316 	GLN	B	162	 292 	GLU	A	Protein	S	4
FT	#SUB	186	 316 	GLN	B	165	 295 	LEU	A	Protein	S	1
FT	#SUB	205	 335 	ARG	B	164	 294 	ALA	A	Protein	S	2
FT	#SUB	205	 335 	ARG	B	165	 295 	LEU	A	Protein	S	4
FT	#SUB	205	 335 	ARG	B	168	 298 	ASN	A	Protein	S	2
FT	#SUB	205	 335 	ARG	B	169	 299 	ASP	A	Protein	S	11
FT	#SUB	209	 339 	ILE	B	168	 298 	ASN	A	Protein	S	2
FT	#HET	103	 233 	TYR	B	6	1003 	FIL	B	S	4
FT	#HET	108	 238 	HIS	B	4	1001 	ZN	B	S	3
FT	#HET	144	 274 	HIS	B	4	1001 	ZN	B	S	3
FT	#HET	145	 275 	ASP	B	4	1001 	ZN	B	S	3
FT	#HET	145	 275 	ASP	B	5	1002 	MG	B	S	3
FT	#HET	174	 304 	GLU	B	5	1002 	MG	B	S	1
FT	#HET	217	 347 	MET	B	6	1003 	FIL	B	S	2
FT	#HET	262	 392 	ASP	B	4	1001 	ZN	B	S	3
FT	#HET	263	 393 	LEU	B	6	1003 	FIL	B	S	1
FT	#HET	265	 395 	ASN	B	6	1003 	FIL	B	S	2
FT	#HET	277	 407 	THR	B	6	1003 	FIL	B	A	3
FT	#HET	280	 410 	ILE	B	6	1003 	FIL	B	S	7
FT	#HET	281	 411 	MET	B	6	1003 	FIL	B	S	2
FT	#HET	284	 414 	PHE	B	6	1003 	FIL	B	S	2
FT	#HET	301	 431 	MET	B	6	1003 	FIL	B	S	2
FT	#HET	312	 442 	SER	B	6	1003 	FIL	B	A	4
FT	#HET	313	 443 	GLN	B	6	1003 	FIL	B	S	7
FT	#HET	316	 446 	PHE	B	6	1003 	FIL	B	S	13
FT	DISORDER	1	32
FT	DISORDER	356	398
CC	SEQUENCE	323 AA (ATOM);
CC	EDHLAKELED LNKWGLNIFN VAGYSHNRPL TXIMYAIFQE RDLLKTFRIS SDTFITYMMT
CC	LEDHYHSDVA YHNSLHAADV AQSTHVLLST PALDAVFTDL EILAAIFAAA IHDVDHPGVS
CC	NQFLINTNSE LALMYNDESV LENHHLAVGF KLLQEEHXDI FMNLTKKQRQ TLRKMVIDMV
CC	LATDMSKHMS LLADLKTMVE TKKVTSSGVL LLDNYTDRIQ VLRNMVHCAD LSNPTKSLEL
CC	YRQWTDRIME EFFQQGDKER ERGMEISPMC DKHTASVEKS QVGFIDYIVH PLWETWADLV
CC	QPDAQDILDT LEDNRNWYQS MIP
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MGSSHHHHHHSSGLVPRGSHMSISRFGVNTENEDHLAKELEDLNKWGLNI
CC	ATOM   --------------------------------EDHLAKELEDLNKWGLNI
CC	                                       ******************
CC	SEQRES FNVAGYSHNRPLTXIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	ATOM   FNVAGYSHNRPLTXIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSD
CC	       **************************************************
CC	SEQRES VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	ATOM   VAYHNSLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPG
CC	       **************************************************
CC	SEQRES VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHXDIFMNLTKKQ
CC	ATOM   VSNQFLINTNSELALMYNDESVLENHHLAVGFKLLQEEHXDIFMNLTKKQ
CC	       **************************************************
CC	SEQRES RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	ATOM   RQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTSSGVLLLDNYTDR
CC	       **************************************************
CC	SEQRES IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	ATOM   IQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEISP
CC	       **************************************************
CC	SEQRES MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	ATOM   MCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWY
CC	       **************************************************
CC	SEQRES QSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHS
CC	ATOM   QSMIP-------------------------------------------
CC	       *****                                           
SQ	SEQUENCE	398 AA;      MW;         CN;
	MGSSHHHHHH SSGLVPRGSH MSISRFGVNT ENEDHLAKEL EDLNKWGLNI FNVAGYSHNR
	PLTXIMYAIF QERDLLKTFR ISSDTFITYM MTLEDHYHSD VAYHNSLHAA DVAQSTHVLL
	STPALDAVFT DLEILAAIFA AAIHDVDHPG VSNQFLINTN SELALMYNDE SVLENHHLAV
	GFKLLQEEHX DIFMNLTKKQ RQTLRKMVID MVLATDMSKH MSLLADLKTM VETKKVTSSG
	VLLLDNYTDR IQVLRNMVHC ADLSNPTKSL ELYRQWTDRI MEEFFQQGDK ERERGMEISP
	MCDKHTASVE KSQVGFIDYI VHPLWETWAD LVQPDAQDIL DTLEDNRNWY QSMIPQSPSP
	PLDEQNRDCQ GLMEKFQFEL TLDEEDSEGP EKEGEGHS
//