ID	1VKGA	STANDARD;	PRT;	377	AA.
DT	CONVERTED FROM PDB (SEQRES) 1VKG
DE	Histone deacetylase 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.200
CC	R-Factor	0.237
FT	#SUB	32	  32 	ALA	A	32	  32 	ALA	B	Protein	A	4
FT	#SUB	32	  32 	ALA	A	33	  33 	LYS	B	Protein	B	1
FT	#SUB	33	  33 	LYS	A	33	  33 	LYS	B	Protein	A	10
FT	#SUB	36	  36 	LYS	A	87	  87 	ASP	B	Protein	S	3
FT	#SUB	87	  87 	ASP	A	36	  36 	LYS	B	Protein	A	4
FT	#SUB	204	 204 	SER	A	353	 353 	ARG	B	Protein	S	2
FT	#SUB	205	 205 	PRO	A	351	 351 	SER	B	Protein	B	2
FT	#SUB	205	 205 	PRO	A	352	 352 	CYS	B	Protein	S	10
FT	#SUB	205	 205 	PRO	A	353	 353 	ARG	B	Protein	A	7
FT	#SUB	206	 206 	GLY	A	271	 271 	GLY	B	Protein	B	1
FT	#SUB	206	 206 	GLY	A	275	 275 	CYS	B	Protein	B	2
FT	#SUB	207	 207 	PHE	A	275	 275 	CYS	B	Protein	A	4
FT	#SUB	275	 275 	CYS	A	206	 206 	GLY	B	Protein	S	3
FT	#SUB	275	 275 	CYS	A	207	 207 	PHE	B	Protein	S	2
FT	#SUB	351	 351 	SER	A	205	 205 	PRO	B	Protein	S	4
FT	#SUB	352	 352 	CYS	A	205	 205 	PRO	B	Protein	A	7
FT	#SUB	353	 353 	ARG	A	205	 205 	PRO	B	Protein	S	4
FT	#SUB	356	 356 	ARG	A	356	 356 	ARG	B	Protein	S	8
FT	#HET	142	 142 	HIS	A	3	402 	CRI	A	S	4
FT	#HET	143	 143 	HIS	A	3	402 	CRI	A	S	14
FT	#HET	151	 151 	GLY	A	3	402 	CRI	A	B	5
FT	#HET	152	 152 	PHE	A	3	402 	CRI	A	S	16
FT	#HET	177	 177 	LEU	A	2	401 	NA	A	B	3
FT	#HET	178	 178 	ASP	A	1	400 	ZN	A	S	3
FT	#HET	178	 178 	ASP	A	2	401 	NA	A	B	3
FT	#HET	178	 178 	ASP	A	3	402 	CRI	A	S	4
FT	#HET	180	 180 	HIS	A	1	400 	ZN	A	A	6
FT	#HET	180	 180 	HIS	A	3	402 	CRI	A	S	18
FT	#HET	200	 200 	LEU	A	2	401 	NA	A	A	3
FT	#HET	208	 208 	PHE	A	3	402 	CRI	A	S	21
FT	#HET	240	 240 	TYR	A	2	401 	NA	A	S	3
FT	#HET	267	 267 	ASP	A	1	400 	ZN	A	S	3
FT	#HET	267	 267 	ASP	A	3	402 	CRI	A	S	1
FT	#HET	268	 268 	THR	A	2	401 	NA	A	S	1
FT	#HET	273	 273 	PRO	A	6	402 	CRI	B	S	8
FT	#HET	274	 274 	MET	A	3	402 	CRI	A	S	3
FT	#HET	274	 274 	MET	A	6	402 	CRI	B	S	4
FT	#HET	277	 277 	PHE	A	2	401 	NA	A	S	1
FT	#HET	306	 306 	TYR	A	3	402 	CRI	A	S	10
FT	#HET	306	 306 	TYR	A	6	402 	CRI	B	A	14
FT	DISORDER	1	14
FT	DISORDER	89	103
CC	SEQUENCE	348 AA (ATOM);
CC	VPVYIYSPEY VSMCDSLAKI PKRASMVHSL IEAYALHKQM RIVKPKVASM EEMATFHTDA
CC	YLQHLQKVSQ EGDDATEGIF DYAAAIGGAT ITAAQCLIDG MCKVAINWSG GWHHAKKDEA
CC	SGFCYLNDAV LGILRLRRKF ERILYVDLDL HHGDGVEDAF SFTSKVMTVS LHKFSPGFFP
CC	GTGDVSDVGL GKGRYYSVNV PIQDGIQDEK YYQICESVLK EVYQAFNPKA VVLQLGADTI
CC	AGDPMCSFNM TPVGIGKCLK YILQWQLATL ILGGGGYNLA NTARCWTYLT GVILGKTLSS
CC	EIPDHEFFTA YGPDYVLEIT PSCRPDRNEP HRIQQILNYI KGNLKHVV
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYAL
CC	ATOM   --------------VPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYAL
CC	                     ************************************
CC	SEQRES HKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
CC	ATOM   HKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDD------------
CC	       **************************************            
CC	SEQRES DCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS
CC	ATOM   ---ATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS
CC	          ***********************************************
CC	SEQRES GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
CC	ATOM   GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
CC	       **************************************************
CC	SEQRES HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKE
CC	ATOM   HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKE
CC	       **************************************************
CC	SEQRES VYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
CC	ATOM   VYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
CC	       **************************************************
CC	SEQRES LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITP
CC	ATOM   LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITP
CC	       **************************************************
CC	SEQRES SCRPDRNEPHRIQQILNYIKGNLKHVV
CC	ATOM   SCRPDRNEPHRIQQILNYIKGNLKHVV
CC	       ***************************
SQ	SEQUENCE	377 AA;      MW;         CN;
	MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL HKQMRIVKPK
	VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI
	TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH
	HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY
	YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI
	LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH
	RIQQILNYIK GNLKHVV
//
ID	1VKGB	STANDARD;	PRT;	377	AA.
DT	CONVERTED FROM PDB (SEQRES) 1VKG
DE	Histone deacetylase 8
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.200
CC	R-Factor	0.237
FT	#SUB	32	  32 	ALA	B	32	  32 	ALA	A	Protein	A	4
FT	#SUB	33	  33 	LYS	B	32	  32 	ALA	A	Protein	S	1
FT	#SUB	33	  33 	LYS	B	33	  33 	LYS	A	Protein	A	10
FT	#SUB	36	  36 	LYS	B	87	  87 	ASP	A	Protein	S	4
FT	#SUB	87	  87 	ASP	B	36	  36 	LYS	A	Protein	S	3
FT	#SUB	205	 205 	PRO	B	351	 351 	SER	A	Protein	A	4
FT	#SUB	205	 205 	PRO	B	352	 352 	CYS	A	Protein	S	7
FT	#SUB	205	 205 	PRO	B	353	 353 	ARG	A	Protein	A	4
FT	#SUB	206	 206 	GLY	B	275	 275 	CYS	A	Protein	B	3
FT	#SUB	207	 207 	PHE	B	275	 275 	CYS	A	Protein	B	2
FT	#SUB	271	 271 	GLY	B	206	 206 	GLY	A	Protein	B	1
FT	#SUB	275	 275 	CYS	B	206	 206 	GLY	A	Protein	S	2
FT	#SUB	275	 275 	CYS	B	207	 207 	PHE	A	Protein	S	4
FT	#SUB	351	 351 	SER	B	205	 205 	PRO	A	Protein	S	2
FT	#SUB	352	 352 	CYS	B	205	 205 	PRO	A	Protein	A	10
FT	#SUB	353	 353 	ARG	B	204	 204 	SER	A	Protein	S	2
FT	#SUB	353	 353 	ARG	B	205	 205 	PRO	A	Protein	S	7
FT	#SUB	356	 356 	ARG	B	356	 356 	ARG	A	Protein	S	8
FT	#HET	142	 142 	HIS	B	6	402 	CRI	B	S	6
FT	#HET	143	 143 	HIS	B	6	402 	CRI	B	S	11
FT	#HET	151	 151 	GLY	B	6	402 	CRI	B	B	10
FT	#HET	152	 152 	PHE	B	3	402 	CRI	A	S	14
FT	#HET	152	 152 	PHE	B	6	402 	CRI	B	A	13
FT	#HET	176	 176 	ASP	B	5	401 	NA	B	A	5
FT	#HET	178	 178 	ASP	B	4	400 	ZN	B	S	3
FT	#HET	178	 178 	ASP	B	5	401 	NA	B	B	3
FT	#HET	178	 178 	ASP	B	6	402 	CRI	B	S	4
FT	#HET	180	 180 	HIS	B	4	400 	ZN	B	A	5
FT	#HET	180	 180 	HIS	B	5	401 	NA	B	B	2
FT	#HET	180	 180 	HIS	B	6	402 	CRI	B	S	22
FT	#HET	199	 199 	SER	B	5	401 	NA	B	S	1
FT	#HET	200	 200 	LEU	B	5	401 	NA	B	B	3
FT	#HET	201	 201 	HIS	B	5	401 	NA	B	A	2
FT	#HET	208	 208 	PHE	B	6	402 	CRI	B	S	19
FT	#HET	267	 267 	ASP	B	4	400 	ZN	B	S	3
FT	#HET	267	 267 	ASP	B	6	402 	CRI	B	S	1
FT	#HET	273	 273 	PRO	B	3	402 	CRI	A	S	11
FT	#HET	274	 274 	MET	B	3	402 	CRI	A	S	4
FT	#HET	274	 274 	MET	B	6	402 	CRI	B	S	3
FT	#HET	306	 306 	TYR	B	3	402 	CRI	A	A	16
FT	#HET	306	 306 	TYR	B	4	400 	ZN	B	S	1
FT	#HET	306	 306 	TYR	B	6	402 	CRI	B	S	7
FT	DISORDER	1	14
FT	DISORDER	89	103
CC	SEQUENCE	348 AA (ATOM);
CC	VPVYIYSPEY VSMCDSLAKI PKRASMVHSL IEAYALHKQM RIVKPKVASM EEMATFHTDA
CC	YLQHLQKVSQ EGDDATEGIF DYAAAIGGAT ITAAQCLIDG MCKVAINWSG GWHHAKKDEA
CC	SGFCYLNDAV LGILRLRRKF ERILYVDLDL HHGDGVEDAF SFTSKVMTVS LHKFSPGFFP
CC	GTGDVSDVGL GKGRYYSVNV PIQDGIQDEK YYQICESVLK EVYQAFNPKA VVLQLGADTI
CC	AGDPMCSFNM TPVGIGKCLK YILQWQLATL ILGGGGYNLA NTARCWTYLT GVILGKTLSS
CC	EIPDHEFFTA YGPDYVLEIT PSCRPDRNEP HRIQQILNYI KGNLKHVV
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MEEPEEPADSGQSLVPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYAL
CC	ATOM   --------------VPVYIYSPEYVSMCDSLAKIPKRASMVHSLIEAYAL
CC	                     ************************************
CC	SEQRES HKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDDDHPDSIEYGLGY
CC	ATOM   HKQMRIVKPKVASMEEMATFHTDAYLQHLQKVSQEGDD------------
CC	       **************************************            
CC	SEQRES DCPATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS
CC	ATOM   ---ATEGIFDYAAAIGGATITAAQCLIDGMCKVAINWSGGWHHAKKDEAS
CC	          ***********************************************
CC	SEQRES GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
CC	ATOM   GFCYLNDAVLGILRLRRKFERILYVDLDLHHGDGVEDAFSFTSKVMTVSL
CC	       **************************************************
CC	SEQRES HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKE
CC	ATOM   HKFSPGFFPGTGDVSDVGLGKGRYYSVNVPIQDGIQDEKYYQICESVLKE
CC	       **************************************************
CC	SEQRES VYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
CC	ATOM   VYQAFNPKAVVLQLGADTIAGDPMCSFNMTPVGIGKCLKYILQWQLATLI
CC	       **************************************************
CC	SEQRES LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITP
CC	ATOM   LGGGGYNLANTARCWTYLTGVILGKTLSSEIPDHEFFTAYGPDYVLEITP
CC	       **************************************************
CC	SEQRES SCRPDRNEPHRIQQILNYIKGNLKHVV
CC	ATOM   SCRPDRNEPHRIQQILNYIKGNLKHVV
CC	       ***************************
SQ	SEQUENCE	377 AA;      MW;         CN;
	MEEPEEPADS GQSLVPVYIY SPEYVSMCDS LAKIPKRASM VHSLIEAYAL HKQMRIVKPK
	VASMEEMATF HTDAYLQHLQ KVSQEGDDDH PDSIEYGLGY DCPATEGIFD YAAAIGGATI
	TAAQCLIDGM CKVAINWSGG WHHAKKDEAS GFCYLNDAVL GILRLRRKFE RILYVDLDLH
	HGDGVEDAFS FTSKVMTVSL HKFSPGFFPG TGDVSDVGLG KGRYYSVNVP IQDGIQDEKY
	YQICESVLKE VYQAFNPKAV VLQLGADTIA GDPMCSFNMT PVGIGKCLKY ILQWQLATLI
	LGGGGYNLAN TARCWTYLTG VILGKTLSSE IPDHEFFTAY GPDYVLEITP SCRPDRNEPH
	RIQQILNYIK GNLKHVV
//