ID	1SM2A	STANDARD;	PRT;	264	AA.
DT	CONVERTED FROM PDB (SEQRES) 1SM2
DE	Tyrosine-protein kinase ITK/TSK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.223
FT	#SUB	230	 586 	HIS	A	260	 616 	ALA	B	Protein	S	1
FT	#SUB	230	 586 	HIS	A	261	 617 	GLU	B	Protein	S	1
FT	#HET	13	 369 	ILE	A	1	301 	STU	A	A	7
FT	#HET	14	 370 	GLY	A	1	301 	STU	A	B	2
FT	#HET	21	 377 	VAL	A	1	301 	STU	A	S	3
FT	#HET	33	 389 	ALA	A	1	301 	STU	A	S	5
FT	#HET	35	 391 	LYS	A	1	301 	STU	A	S	4
FT	#HET	79	 435 	PHE	A	1	301 	STU	A	S	6
FT	#HET	80	 436 	GLU	A	1	301 	STU	A	B	3
FT	#HET	81	 437 	PHE	A	1	301 	STU	A	A	10
FT	#HET	82	 438 	MET	A	1	301 	STU	A	A	11
FT	#HET	85	 441 	GLY	A	1	301 	STU	A	B	4
FT	#HET	86	 442 	CYS	A	1	301 	STU	A	S	2
FT	#HET	130	 486 	ARG	A	1	301 	STU	A	B	6
FT	#HET	131	 487 	ASN	A	1	301 	STU	A	B	1
FT	#HET	133	 489 	LEU	A	1	301 	STU	A	S	9
FT	#HET	143	 499 	SER	A	1	301 	STU	A	S	1
FT	#HET	144	 500 	ASP	A	1	301 	STU	A	S	11
FT	DISORDER	147	164
FT	DISORDER	264	264
CC	SEQUENCE	245 AA (ATOM);
CC	VIDPSELTFV QEIGSGQFGL VHLGYWLNKD KVAIKTIREG AMSEEDFIEE AEVMMKLSHP
CC	KLVQLYGVCL EQAPICLVFE FMEHGCLSDY LRTQRGLFAA ETLLGMCLDV CEGMAYLEEA
CC	CVIHRDLAAR NCLVGENQVI KVSDFGPVKW ASPEVFSFSR YSSKSDVWSF GVLMWEVFSE
CC	GKIPYENRSN SEVVEDISTG FRLYKPRLAS THVYQIMNHC WKERPEDRPA FSRLLRQLAE
CC	IAESG
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEE
CC	ATOM   VIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEE
CC	       **************************************************
CC	SEQRES AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAA
CC	ATOM   AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAA
CC	       **************************************************
CC	SEQRES ETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF
CC	ATOM   ETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFG----
CC	       **********************************************    
CC	SEQRES VLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK
CC	ATOM   --------------PVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK
CC	                     ************************************
CC	SEQRES IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFS
CC	ATOM   IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFS
CC	       **************************************************
CC	SEQRES RLLRQLAEIAESGL
CC	ATOM   RLLRQLAEIAESG-
CC	       ************* 
SQ	SEQUENCE	264 AA;      MW;         CN;
	VIDPSELTFV QEIGSGQFGL VHLGYWLNKD KVAIKTIREG AMSEEDFIEE AEVMMKLSHP
	KLVQLYGVCL EQAPICLVFE FMEHGCLSDY LRTQRGLFAA ETLLGMCLDV CEGMAYLEEA
	CVIHRDLAAR NCLVGENQVI KVSDFGMTRF VLDDQYTSST GTKFPVKWAS PEVFSFSRYS
	SKSDVWSFGV LMWEVFSEGK IPYENRSNSE VVEDISTGFR LYKPRLASTH VYQIMNHCWK
	ERPEDRPAFS RLLRQLAEIA ESGL
//
ID	1SM2B	STANDARD;	PRT;	264	AA.
DT	CONVERTED FROM PDB (SEQRES) 1SM2
DE	Tyrosine-protein kinase ITK/TSK
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.300
CC	R-Factor	0.223
FT	#SUB	260	 616 	ALA	B	230	 586 	HIS	A	Protein	B	1
FT	#SUB	261	 617 	GLU	B	230	 586 	HIS	A	Protein	B	1
FT	#HET	13	 369 	ILE	B	2	621 	STU	B	A	9
FT	#HET	14	 370 	GLY	B	2	621 	STU	B	B	2
FT	#HET	21	 377 	VAL	B	2	621 	STU	B	S	8
FT	#HET	33	 389 	ALA	B	2	621 	STU	B	S	6
FT	#HET	35	 391 	LYS	B	2	621 	STU	B	S	5
FT	#HET	63	 419 	VAL	B	2	621 	STU	B	S	2
FT	#HET	79	 435 	PHE	B	2	621 	STU	B	S	5
FT	#HET	80	 436 	GLU	B	2	621 	STU	B	B	4
FT	#HET	81	 437 	PHE	B	2	621 	STU	B	A	5
FT	#HET	82	 438 	MET	B	2	621 	STU	B	A	13
FT	#HET	85	 441 	GLY	B	2	621 	STU	B	B	4
FT	#HET	86	 442 	CYS	B	2	621 	STU	B	S	1
FT	#HET	130	 486 	ARG	B	2	621 	STU	B	A	8
FT	#HET	131	 487 	ASN	B	2	621 	STU	B	A	2
FT	#HET	133	 489 	LEU	B	2	621 	STU	B	S	11
FT	#HET	143	 499 	SER	B	2	621 	STU	B	S	1
FT	#HET	144	 500 	ASP	B	2	621 	STU	B	A	5
FT	DISORDER	1	1
FT	DISORDER	146	164
FT	DISORDER	262	264
CC	SEQUENCE	241 AA (ATOM);
CC	IDPSELTFVQ EIGSGQFGLV HLGYWLNKDK VAIKTIREGA MSEEDFIEEA EVMMKLSHPK
CC	LVQLYGVCLE QAPICLVFEF MEHGCLSDYL RTQRGLFAAE TLLGMCLDVC EGMAYLEEAC
CC	VIHRDLAARN CLVGENQVIK VSDFPVKWAS PEVFSFSRYS SKSDVWSFGV LMWEVFSEGK
CC	IPYENRSNSE VVEDISTGFR LYKPRLASTH VYQIMNHCWK ERPEDRPAFS RLLRQLAEIA
CC	E
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VIDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEE
CC	ATOM   -IDPSELTFVQEIGSGQFGLVHLGYWLNKDKVAIKTIREGAMSEEDFIEE
CC	        *************************************************
CC	SEQRES AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAA
CC	ATOM   AEVMMKLSHPKLVQLYGVCLEQAPICLVFEFMEHGCLSDYLRTQRGLFAA
CC	       **************************************************
CC	SEQRES ETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDFGMTRF
CC	ATOM   ETLLGMCLDVCEGMAYLEEACVIHRDLAARNCLVGENQVIKVSDF-----
CC	       *********************************************     
CC	SEQRES VLDDQYTSSTGTKFPVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK
CC	ATOM   --------------PVKWASPEVFSFSRYSSKSDVWSFGVLMWEVFSEGK
CC	                     ************************************
CC	SEQRES IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFS
CC	ATOM   IPYENRSNSEVVEDISTGFRLYKPRLASTHVYQIMNHCWKERPEDRPAFS
CC	       **************************************************
CC	SEQRES RLLRQLAEIAESGL
CC	ATOM   RLLRQLAEIAE---
CC	       ***********   
SQ	SEQUENCE	264 AA;      MW;         CN;
	VIDPSELTFV QEIGSGQFGL VHLGYWLNKD KVAIKTIREG AMSEEDFIEE AEVMMKLSHP
	KLVQLYGVCL EQAPICLVFE FMEHGCLSDY LRTQRGLFAA ETLLGMCLDV CEGMAYLEEA
	CVIHRDLAAR NCLVGENQVI KVSDFGMTRF VLDDQYTSST GTKFPVKWAS PEVFSFSRYS
	SKSDVWSFGV LMWEVFSEGK IPYENRSNSE VVEDISTGFR LYKPRLASTH VYQIMNHCWK
	ERPEDRPAFS RLLRQLAEIA ESGL
//