ID	1R9OA	STANDARD;	PRT;	477	AA.
DT	CONVERTED FROM PDB (SEQRES) 1R9O
DE	Cytochrome P450 2C9
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.194
FT	#HET	80	  97 	ARG	A	1	500 	HEM	A	S	7
FT	#HET	91	 108 	ARG	A	2	501 	FLP	A	S	10
FT	#HET	95	 112 	ILE	A	1	500 	HEM	A	A	4
FT	#HET	96	 113 	VAL	A	1	500 	HEM	A	A	4
FT	#HET	96	 113 	VAL	A	2	501 	FLP	A	S	2
FT	#HET	97	 114 	PHE	A	2	501 	FLP	A	S	1
FT	#HET	103	 120 	TRP	A	1	500 	HEM	A	S	5
FT	#HET	107	 124 	ARG	A	1	500 	HEM	A	S	1
FT	#HET	187	 204 	ASN	A	2	501 	FLP	A	S	2
FT	#HET	188	 205 	ILE	A	2	501 	FLP	A	S	2
FT	#HET	188	 205 	ILE	A	3	502 	GOL	A	S	1
FT	#HET	191	 208 	LEU	A	2	501 	FLP	A	S	2
FT	#HET	220	 237 	VAL	A	2	501 	FLP	A	S	1
FT	#HET	223	 240 	MET	A	2	501 	FLP	A	S	1
FT	#HET	275	 292 	VAL	A	2	501 	FLP	A	S	2
FT	#HET	276	 293 	ASP	A	2	501 	FLP	A	A	4
FT	#HET	277	 294 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	279	 296 	GLY	A	2	501 	FLP	A	B	7
FT	#HET	280	 297 	ALA	A	1	500 	HEM	A	A	10
FT	#HET	280	 297 	ALA	A	2	501 	FLP	A	A	11
FT	#HET	281	 298 	GLY	A	1	500 	HEM	A	B	7
FT	#HET	283	 300 	GLU	A	3	502 	GOL	A	S	2
FT	#HET	284	 301 	THR	A	1	500 	HEM	A	S	8
FT	#HET	284	 301 	THR	A	2	501 	FLP	A	S	1
FT	#HET	285	 302 	THR	A	1	500 	HEM	A	A	3
FT	#HET	288	 305 	THR	A	1	500 	HEM	A	S	2
FT	#HET	339	 356 	GLN	A	1	500 	HEM	A	S	1
FT	#HET	344	 361 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	345	 362 	LEU	A	1	500 	HEM	A	S	4
FT	#HET	345	 362 	LEU	A	3	502 	GOL	A	S	1
FT	#HET	348	 365 	SER	A	1	500 	HEM	A	S	6
FT	#HET	349	 366 	LEU	A	1	500 	HEM	A	A	2
FT	#HET	349	 366 	LEU	A	2	501 	FLP	A	S	1
FT	#HET	351	 368 	HIS	A	1	500 	HEM	A	S	6
FT	#HET	374	 391 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	410	 427 	PRO	A	1	500 	HEM	A	B	3
FT	#HET	411	 428 	PHE	A	1	500 	HEM	A	A	11
FT	#HET	412	 429 	SER	A	1	500 	HEM	A	S	6
FT	#HET	416	 433 	ARG	A	1	500 	HEM	A	A	14
FT	#HET	418	 435 	CYS	A	1	500 	HEM	A	A	19
FT	#HET	419	 436 	VAL	A	1	500 	HEM	A	S	2
FT	#HET	420	 437 	GLY	A	1	500 	HEM	A	B	5
FT	#HET	423	 440 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	424	 441 	ALA	A	1	500 	HEM	A	S	2
FT	#HET	427	 444 	GLU	A	1	500 	HEM	A	S	1
FT	#HET	428	 445 	LEU	A	1	500 	HEM	A	S	1
FT	#HET	460	 477 	ALA	A	3	502 	GOL	A	S	2
FT	DISORDER	1	8
FT	DISORDER	21	25
FT	DISORDER	197	203
FT	DISORDER	476	477
CC	SEQUENCE	455 AA (ATOM);
CC	RGKLPPGPTP LPLQIGIKDI SKSLTNLSKV YGPVFTLYFG LKPIVVLHGY EAVKEALIDL
CC	GEEFSGRGIF PLAERANRGF GIVFSNGKKW KEIRRFSLMT LRNFGMGKRS IEDRVQEEAR
CC	CLVEELRKTK ASPCDPTFIL GCAPCNVICS IIFHKRFDYK DQQFLNLMEK LNENIKILSS
CC	PWIPIIDYFP GTHNKLLKNV AFMKSYILEK VKEHQESMDM NNPQDFIDCF LMKMEKEKHN
CC	QPSEFTIESL ENTAVDLFGA GTETTSTTLR YALLLLLKHP EVTAKVQEEI ERVIGRNRSP
CC	CMQDRSHMPY TDAVVHEVQR YIDLLPTSLP HAVTCDIKFR NYLIPKGTTI LISLTSVLHD
CC	NKEFPNPEMF DPHHFLDEGG NFKKSKYFMP FSAGKRICVG EALAGMELFL FLTSILQNFN
CC	LKSLVDPKNL DTTPVVNGFA SVPPFYQLCF IPIHH
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MAKKTSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTL
CC	ATOM   --------RGKLPPGPTPLP-----LQIGIKDISKSLTNLSKVYGPVFTL
CC	               ************     *************************
CC	SEQRES YFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG
CC	ATOM   YFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNG
CC	       **************************************************
CC	SEQRES KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPT
CC	ATOM   KKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPT
CC	       **************************************************
CC	SEQRES FILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICN
CC	ATOM   FILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWI----
CC	       **********************************************    
CC	SEQRES NFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCF
CC	ATOM   ---PIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCF
CC	          ***********************************************
CC	SEQRES LMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHP
CC	ATOM   LMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHP
CC	       **************************************************
CC	SEQRES EVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLP
CC	ATOM   EVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLP
CC	       **************************************************
CC	SEQRES HAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGG
CC	ATOM   HAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGG
CC	       **************************************************
CC	SEQRES NFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNL
CC	ATOM   NFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNL
CC	       **************************************************
CC	SEQRES DTTPVVNGFASVPPFYQLCFIPIHHHH
CC	ATOM   DTTPVVNGFASVPPFYQLCFIPIHH--
CC	       *************************  
SQ	SEQUENCE	477 AA;      MW;         CN;
	MAKKTSSGRG KLPPGPTPLP VIGNILQIGI KDISKSLTNL SKVYGPVFTL YFGLKPIVVL
	HGYEAVKEAL IDLGEEFSGR GIFPLAERAN RGFGIVFSNG KKWKEIRRFS LMTLRNFGMG
	KRSIEDRVQE EARCLVEELR KTKASPCDPT FILGCAPCNV ICSIIFHKRF DYKDQQFLNL
	MEKLNENIKI LSSPWIQICN NFSPIIDYFP GTHNKLLKNV AFMKSYILEK VKEHQESMDM
	NNPQDFIDCF LMKMEKEKHN QPSEFTIESL ENTAVDLFGA GTETTSTTLR YALLLLLKHP
	EVTAKVQEEI ERVIGRNRSP CMQDRSHMPY TDAVVHEVQR YIDLLPTSLP HAVTCDIKFR
	NYLIPKGTTI LISLTSVLHD NKEFPNPEMF DPHHFLDEGG NFKKSKYFMP FSAGKRICVG
	EALAGMELFL FLTSILQNFN LKSLVDPKNL DTTPVVNGFA SVPPFYQLCF IPIHHHH
//