ID	1DRFA	STANDARD;	PRT;	186	AA.
DT	CONVERTED FROM PDB (SEQRES) 1DRF
DE	DIHYDROFOLATE REDUCTASE
OS	Homo sapiens
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.000
CC	R-Factor	0.189
FT	#HET	7	   7 	ILE	A	3	187 	FOL	A	A	5
FT	#HET	8	   8 	VAL	A	3	187 	FOL	A	B	9
FT	#HET	9	   9 	ALA	A	3	187 	FOL	A	A	8
FT	#HET	22	  22 	LEU	A	3	187 	FOL	A	S	1
FT	#HET	30	  30 	GLU	A	3	187 	FOL	A	S	11
FT	#HET	31	  31 	PHE	A	3	187 	FOL	A	A	13
FT	#HET	32	  32 	ARG	A	3	187 	FOL	A	A	2
FT	#HET	34	  34 	PHE	A	3	187 	FOL	A	S	15
FT	#HET	35	  35 	GLN	A	3	187 	FOL	A	A	7
FT	#HET	53	  53 	GLY	A	2	614 	SO4	A	B	9
FT	#HET	54	  54 	LYS	A	1	613 	SO4	A	S	5
FT	#HET	54	  54 	LYS	A	2	614 	SO4	A	B	5
FT	#HET	55	  55 	LYS	A	2	614 	SO4	A	A	10
FT	#HET	56	  56 	THR	A	2	614 	SO4	A	A	7
FT	#HET	59	  59 	SER	A	3	187 	FOL	A	S	1
FT	#HET	60	  60 	ILE	A	3	187 	FOL	A	S	6
FT	#HET	61	  61 	PRO	A	3	187 	FOL	A	S	1
FT	#HET	64	  64 	ASN	A	3	187 	FOL	A	S	3
FT	#HET	67	  67 	LEU	A	3	187 	FOL	A	S	1
FT	#HET	70	  70 	ARG	A	3	187 	FOL	A	S	8
FT	#HET	75	  75 	LEU	A	1	613 	SO4	A	B	1
FT	#HET	76	  76 	SER	A	1	613 	SO4	A	A	8
FT	#HET	77	  77 	ARG	A	1	613 	SO4	A	A	6
FT	#HET	78	  78 	GLU	A	1	613 	SO4	A	A	5
FT	#HET	115	 115 	VAL	A	3	187 	FOL	A	B	5
FT	#HET	116	 116 	GLY	A	2	614 	SO4	A	B	3
FT	#HET	117	 117 	GLY	A	2	614 	SO4	A	B	7
FT	#HET	120	 120 	VAL	A	2	614 	SO4	A	S	1
FT	#HET	121	 121 	TYR	A	3	187 	FOL	A	S	2
FT	#HET	136	 136 	THR	A	3	187 	FOL	A	S	2
CC	Miss-SC	1
CC	SEQUENCE	186 AA (ATOM);
CC	VGSLNCIVAV SQNMGIGKNG DLPWPPLRNE FRYFQRMTTT SSVEGKQNLV IMGKKTWFSI
CC	PEKNRPLKGR INLVLSRELK EPPQGAHFLS RSLDDALKLT EQPELANKVD MVWIVGGSSV
CC	YKEAMNHPGH LKLFVTRIMQ DFESDTFFPE IDLEKYKLLP EYPGVLSDVQ EEKGIKYKFE
CC	VYEKND
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLV
CC	ATOM   VGSLNCIVAVSQNMGIGKNGDLPWPPLRNEFRYFQRMTTTSSVEGKQNLV
CC	       **************************************************
CC	SEQRES IMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLT
CC	ATOM   IMGKKTWFSIPEKNRPLKGRINLVLSRELKEPPQGAHFLSRSLDDALKLT
CC	       **************************************************
CC	SEQRES EQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPE
CC	ATOM   EQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPE
CC	       **************************************************
CC	SEQRES IDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
CC	ATOM   IDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
CC	       ************************************
SQ	SEQUENCE	186 AA;      MW;         CN;
	VGSLNCIVAV SQNMGIGKNG DLPWPPLRNE FRYFQRMTTT SSVEGKQNLV IMGKKTWFSI
	PEKNRPLKGR INLVLSRELK EPPQGAHFLS RSLDDALKLT EQPELANKVD MVWIVGGSSV
	YKEAMNHPGH LKLFVTRIMQ DFESDTFFPE IDLEKYKLLP EYPGVLSDVQ EEKGIKYKFE
	VYEKND
//