ID	1DDRA	STANDARD;	PRT;	159	AA.
DT	CONVERTED FROM PDB (SEQRES) 1DDR
DE	DIHYDROFOLATE REDUCTASE
OS	Escherichia coli
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.156
FT	#SUB	17	  17 	GLU	A	145	 145 	ALA	B	Protein	B	2
FT	#SUB	18	  18 	ASN	A	143	 143 	ALA	B	Protein	S	5
FT	#SUB	18	  18 	ASN	A	144	 144 	ASP	B	Protein	A	5
FT	#SUB	19	  19 	ALA	A	144	 144 	ASP	B	Protein	B	1
FT	#SUB	19	  19 	ALA	A	145	 145 	ALA	B	Protein	A	4
FT	#SUB	19	  19 	ALA	A	146	 146 	GLN	B	Protein	S	3
FT	#SUB	19	  19 	ALA	A	147	 147 	ASN	B	Protein	A	3
FT	#SUB	19	  19 	ALA	A	148	 148 	SER	B	Protein	A	4
FT	#SUB	20	  20 	MET	A	148	 148 	SER	B	Protein	B	2
FT	#SUB	21	  21 	PRO	A	21	  21 	PRO	B	Protein	B	3
FT	#SUB	21	  21 	PRO	A	148	 148 	SER	B	Protein	B	3
FT	#SUB	21	  21 	PRO	A	149	 149 	HIS	B	Protein	S	1
FT	#SUB	22	  22 	TRP	A	21	  21 	PRO	B	Protein	B	2
FT	#SUB	22	  22 	TRP	A	22	  22 	TRP	B	Protein	B	8
FT	#SUB	22	  22 	TRP	A	23	  23 	ASN	B	Protein	B	2
FT	#SUB	23	  23 	ASN	A	20	  20 	MET	B	Protein	S	2
FT	#SUB	23	  23 	ASN	A	22	  22 	TRP	B	Protein	S	4
FT	#SUB	48	  48 	GLU	A	145	 145 	ALA	B	Protein	B	1
FT	#SUB	48	  48 	GLU	A	146	 146 	GLN	B	Protein	B	1
FT	#SUB	49	  49 	SER	A	145	 145 	ALA	B	Protein	A	8
FT	#SUB	49	  49 	SER	A	146	 146 	GLN	B	Protein	B	3
FT	#SUB	51	  51 	GLY	A	146	 146 	GLN	B	Protein	B	1
FT	#SUB	143	 143 	ALA	A	18	  18 	ASN	B	Protein	A	7
FT	#SUB	144	 144 	ASP	A	18	  18 	ASN	B	Protein	B	6
FT	#SUB	144	 144 	ASP	A	19	  19 	ALA	B	Protein	B	4
FT	#SUB	145	 145 	ALA	A	19	  19 	ALA	B	Protein	B	3
FT	#SUB	145	 145 	ALA	A	49	  49 	SER	B	Protein	B	1
FT	#SUB	146	 146 	GLN	A	19	  19 	ALA	B	Protein	B	3
FT	#SUB	146	 146 	GLN	A	48	  48 	GLU	B	Protein	S	1
FT	#SUB	146	 146 	GLN	A	49	  49 	SER	B	Protein	S	1
FT	#SUB	147	 147 	ASN	A	19	  19 	ALA	B	Protein	B	2
FT	#SUB	148	 148 	SER	A	19	  19 	ALA	B	Protein	A	7
FT	#SUB	148	 148 	SER	A	20	  20 	MET	B	Protein	S	3
FT	#HET	5	   5 	ILE	A	2	200 	MTX	A	A	9
FT	#HET	6	   6 	ALA	A	2	200 	MTX	A	B	12
FT	#HET	7	   7 	ALA	A	2	200 	MTX	A	A	4
FT	#HET	27	  27 	ASP	A	2	200 	MTX	A	S	6
FT	#HET	28	  28 	LEU	A	2	200 	MTX	A	A	3
FT	#HET	31	  31 	PHE	A	2	200 	MTX	A	S	16
FT	#HET	32	  32 	LYS	A	2	200 	MTX	A	A	10
FT	#HET	43	  43 	GLY	A	1	201 	CL	A	B	2
FT	#HET	44	  44 	ARG	A	1	201 	CL	A	B	2
FT	#HET	44	  44 	ARG	A	3	211 	URE	A	S	6
FT	#HET	45	  45 	HIS	A	1	201 	CL	A	A	5
FT	#HET	45	  45 	HIS	A	3	211 	URE	A	S	1
FT	#HET	46	  46 	THR	A	2	200 	MTX	A	S	1
FT	#HET	49	  49 	SER	A	2	200 	MTX	A	S	1
FT	#HET	50	  50 	ILE	A	2	200 	MTX	A	S	2
FT	#HET	52	  52 	ARG	A	2	200 	MTX	A	S	4
FT	#HET	52	  52 	ARG	A	4	212 	URE	A	S	6
FT	#HET	54	  54 	LEU	A	2	200 	MTX	A	S	4
FT	#HET	57	  57 	ARG	A	2	200 	MTX	A	S	9
FT	#HET	63	  63 	SER	A	3	211 	URE	A	S	3
FT	#HET	64	  64 	SER	A	5	213 	URE	A	S	1
FT	#HET	65	  65 	GLN	A	3	211 	URE	A	S	2
FT	#HET	76	  76 	LYS	A	5	213 	URE	A	B	3
FT	#HET	94	  94 	ILE	A	2	200 	MTX	A	A	5
FT	#HET	100	 100 	TYR	A	2	200 	MTX	A	S	1
FT	#HET	113	 113 	THR	A	2	200 	MTX	A	S	1
CC	Miss-SC	1
CC	SEQUENCE	159 AA (ATOM);
CC	MISLIAALAV DRVIGMENAM PWNLPADLAW FKRNTLNKPV IMGRHTWESI GRPLPGRKNI
CC	ILSSQPGTDD RVTWVKSVDE AIAACGDVPE IMVIGGGRVY EQFLPKAQKL YLTHIDAEVE
CC	GDTHFPDYEP DDWESVFSEF HDADAQNSHS YCFEILERR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
CC	ATOM   MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
CC	       **************************************************
CC	SEQRES GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
CC	ATOM   GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
CC	       **************************************************
CC	SEQRES EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
CC	ATOM   EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
CC	       **************************************************
CC	SEQRES YCFEILERR
CC	ATOM   YCFEILERR
CC	       *********
SQ	SEQUENCE	159 AA;      MW;         CN;
	MISLIAALAV DRVIGMENAM PWNLPADLAW FKRNTLNKPV IMGRHTWESI GRPLPGRKNI
	ILSSQPGTDD RVTWVKSVDE AIAACGDVPE IMVIGGGRVY EQFLPKAQKL YLTHIDAEVE
	GDTHFPDYEP DDWESVFSEF HDADAQNSHS YCFEILERR
//
ID	1DDRB	STANDARD;	PRT;	159	AA.
DT	CONVERTED FROM PDB (SEQRES) 1DDR
DE	DIHYDROFOLATE REDUCTASE
OS	Escherichia coli
CC	EXPDTA	X-RAY DIFFRACTION
CC	RESOLU	2.450
CC	R-Factor	0.156
FT	#SUB	18	  18 	ASN	B	143	 143 	ALA	A	Protein	S	7
FT	#SUB	18	  18 	ASN	B	144	 144 	ASP	A	Protein	A	6
FT	#SUB	19	  19 	ALA	B	144	 144 	ASP	A	Protein	A	4
FT	#SUB	19	  19 	ALA	B	145	 145 	ALA	A	Protein	A	3
FT	#SUB	19	  19 	ALA	B	146	 146 	GLN	A	Protein	S	3
FT	#SUB	19	  19 	ALA	B	147	 147 	ASN	A	Protein	S	2
FT	#SUB	19	  19 	ALA	B	148	 148 	SER	A	Protein	A	7
FT	#SUB	20	  20 	MET	B	23	  23 	ASN	A	Protein	B	2
FT	#SUB	20	  20 	MET	B	148	 148 	SER	A	Protein	B	3
FT	#SUB	21	  21 	PRO	B	21	  21 	PRO	A	Protein	B	3
FT	#SUB	21	  21 	PRO	B	22	  22 	TRP	A	Protein	B	2
FT	#SUB	22	  22 	TRP	B	22	  22 	TRP	A	Protein	B	8
FT	#SUB	22	  22 	TRP	B	23	  23 	ASN	A	Protein	B	4
FT	#SUB	23	  23 	ASN	B	22	  22 	TRP	A	Protein	A	2
FT	#SUB	48	  48 	GLU	B	146	 146 	GLN	A	Protein	B	1
FT	#SUB	49	  49 	SER	B	145	 145 	ALA	A	Protein	S	1
FT	#SUB	49	  49 	SER	B	146	 146 	GLN	A	Protein	B	1
FT	#SUB	143	 143 	ALA	B	18	  18 	ASN	A	Protein	A	5
FT	#SUB	144	 144 	ASP	B	18	  18 	ASN	A	Protein	B	5
FT	#SUB	144	 144 	ASP	B	19	  19 	ALA	A	Protein	B	1
FT	#SUB	145	 145 	ALA	B	17	  17 	GLU	A	Protein	B	2
FT	#SUB	145	 145 	ALA	B	19	  19 	ALA	A	Protein	B	4
FT	#SUB	145	 145 	ALA	B	48	  48 	GLU	A	Protein	S	1
FT	#SUB	145	 145 	ALA	B	49	  49 	SER	A	Protein	A	8
FT	#SUB	146	 146 	GLN	B	19	  19 	ALA	A	Protein	B	3
FT	#SUB	146	 146 	GLN	B	48	  48 	GLU	A	Protein	S	1
FT	#SUB	146	 146 	GLN	B	49	  49 	SER	A	Protein	S	3
FT	#SUB	146	 146 	GLN	B	51	  51 	GLY	A	Protein	S	1
FT	#SUB	147	 147 	ASN	B	19	  19 	ALA	A	Protein	B	3
FT	#SUB	148	 148 	SER	B	19	  19 	ALA	A	Protein	A	4
FT	#SUB	148	 148 	SER	B	20	  20 	MET	A	Protein	S	2
FT	#SUB	148	 148 	SER	B	21	  21 	PRO	A	Protein	S	3
FT	#SUB	149	 149 	HIS	B	21	  21 	PRO	A	Protein	S	1
FT	#HET	5	   5 	ILE	B	8	200 	MTX	B	A	10
FT	#HET	6	   6 	ALA	B	8	200 	MTX	B	B	13
FT	#HET	7	   7 	ALA	B	8	200 	MTX	B	A	4
FT	#HET	27	  27 	ASP	B	8	200 	MTX	B	S	7
FT	#HET	28	  28 	LEU	B	8	200 	MTX	B	A	5
FT	#HET	30	  30 	TRP	B	8	200 	MTX	B	S	2
FT	#HET	31	  31 	PHE	B	8	200 	MTX	B	S	15
FT	#HET	32	  32 	LYS	B	8	200 	MTX	B	S	3
FT	#HET	43	  43 	GLY	B	6	202 	CL	B	B	4
FT	#HET	44	  44 	ARG	B	6	202 	CL	B	B	2
FT	#HET	45	  45 	HIS	B	6	202 	CL	B	A	5
FT	#HET	46	  46 	THR	B	6	202 	CL	B	B	1
FT	#HET	50	  50 	ILE	B	8	200 	MTX	B	S	4
FT	#HET	52	  52 	ARG	B	8	200 	MTX	B	S	5
FT	#HET	54	  54 	LEU	B	8	200 	MTX	B	S	4
FT	#HET	57	  57 	ARG	B	8	200 	MTX	B	S	7
FT	#HET	57	  57 	ARG	B	10	215 	URE	B	B	2
FT	#HET	58	  58 	LYS	B	10	215 	URE	B	B	2
FT	#HET	59	  59 	ASN	B	10	215 	URE	B	A	8
FT	#HET	71	  71 	ARG	B	10	215 	URE	B	B	5
FT	#HET	72	  72 	VAL	B	10	215 	URE	B	B	3
FT	#HET	73	  73 	THR	B	10	215 	URE	B	B	1
FT	#HET	94	  94 	ILE	B	8	200 	MTX	B	A	4
FT	#HET	100	 100 	TYR	B	8	200 	MTX	B	S	1
FT	#HET	111	 111 	TYR	B	8	200 	MTX	B	B	1
FT	#HET	113	 113 	THR	B	8	200 	MTX	B	S	1
FT	#HET	122	 122 	ASP	B	9	214 	URE	B	B	3
FT	#HET	123	 123 	THR	B	9	214 	URE	B	A	6
FT	#HET	124	 124 	HIS	B	9	214 	URE	B	A	8
FT	#HET	135	 135 	SER	B	7	203 	CA	B	B	1
CC	SEQUENCE	159 AA (ATOM);
CC	MISLIAALAV DRVIGMENAM PWNLPADLAW FKRNTLNKPV IMGRHTWESI GRPLPGRKNI
CC	ILSSQPGTDD RVTWVKSVDE AIAACGDVPE IMVIGGGRVY EQFLPKAQKL YLTHIDAEVE
CC	GDTHFPDYEP DDWESVFSEF HDADAQNSHS YCFEILERR
CC	!----
CC	ALIGNMENT OF SEQRES AND ATOMRES
CC	SEQRES MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
CC	ATOM   MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGRHTWESI
CC	       **************************************************
CC	SEQRES GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
CC	ATOM   GRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVY
CC	       **************************************************
CC	SEQRES EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
CC	ATOM   EQFLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHS
CC	       **************************************************
CC	SEQRES YCFEILERR
CC	ATOM   YCFEILERR
CC	       *********
SQ	SEQUENCE	159 AA;      MW;         CN;
	MISLIAALAV DRVIGMENAM PWNLPADLAW FKRNTLNKPV IMGRHTWESI GRPLPGRKNI
	ILSSQPGTDD RVTWVKSVDE AIAACGDVPE IMVIGGGRVY EQFLPKAQKL YLTHIDAEVE
	GDTHFPDYEP DDWESVFSEF HDADAQNSHS YCFEILERR
//