1	B43	4-amino-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-D]pyrimidin-7-yl-cyclopentane	1.000
2	VSF	5-(4-phenoxyphenyl)-7-(tetrahydro-2h-pyran-4-yl)-7h-pyrrolo[2,3-D]pyrimidin-4-amine	0.900
3	VSG	7-(1-methylpiperidin-4-yl)-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-D]pyrimidin-4-amine	0.871
4	A1BKW	3-(4-phenoxyphenyl)-1-[(3s)-piperidin-3-yl]-1h-pyrazolo[3,4-D]pyrimidin-4-amine	0.839
5	A1EKY	3-(4-phenoxyphenyl)-1-piperidin-4-yl-pyrazolo[3,4-D]pyrimidin-4-amine	0.839
6	W0O	1-(1-methylpiperidin-4-yl)-3-(4-phenoxyphenyl)pyrazolo[3,4-D]pyrimidin-4-amine	0.812
7	A1BJE	3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-D]pyrimidin-4-amine	0.759
8	1E8	1-{(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-D]pyrimidin-1-yl]piperidin-1-yl}prop-2-en-1-one	0.743
9	8E8	1-[(3~{R})-3-[4-azanyl-3-(4-phenoxyphenyl)pyrazolo[3,4-D]pyrimidin-1-yl]piperidin-1-yl]propan-1-one	0.743
10	A1H14	Ibrutinib (unbound form)	0.743
11	VSB	7-[cis-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-D]pyrimidin-4-amine	0.730
12	VSE	7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7h-pyrrolo[2,3-D]pyrimidin-4-amine	0.730
13	A1BI1	{(3r)-3-[4-amino-3-(4-phenoxyphenyl)-1h-pyrazolo[3,4-D]pyrimidin-1-yl]piperidin-1-yl}(cyclopropyl)methanone	0.722